KEGG   Geobacillus stearothermophilus: GT50_11035
Entry
GT50_11035        CDS       T04043                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
gse  Geobacillus stearothermophilus
Pathway
gse03030  DNA replication
gse03410  Base excision repair
gse03420  Nucleotide excision repair
gse03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:gse00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    GT50_11035 (ligA)
   03410 Base excision repair
    GT50_11035 (ligA)
   03420 Nucleotide excision repair
    GT50_11035 (ligA)
   03430 Mismatch repair
    GT50_11035 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:gse03032]
    GT50_11035 (ligA)
   03400 DNA repair and recombination proteins [BR:gse03400]
    GT50_11035 (ligA)
Enzymes [BR:gse01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     GT50_11035 (ligA)
DNA replication proteins [BR:gse03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     GT50_11035 (ligA)
DNA repair and recombination proteins [BR:gse03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     GT50_11035 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     GT50_11035 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     GT50_11035 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      GT50_11035 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden OB_DNA_ligase HHH_2 HHH_5 BRCT DNA_ligase_ZBD HHH PTCB-BRCT Nlig-Ia RNA_pol_A_CTD HHH_3 BRCT_2 Gly_reductase
Other DBs
NCBI-ProteinID: ALA70651
LinkDB
Position
2065493..2067505
AA seq 670 aa
MDRQQAERRAAELRELLHRYGYEYYVLDRPSVPDAEYDRLMQELMAIEEQYPELKTSDSP
TQRIGGPPLEAFRKVTHVVPMMSLANAFDEGDLRDFDRRVRQEVGEAAYVCELKIDGLAV
SVRYEDGYFVQGATRGDGTTGEDITENLRTIRSLPLRLKEPVSLEARGEAFMPKASFLRL
NEERKARGEELFANPRNAAAGSLRQLDPKVAASRQLDLYVYGLANAEELGIESHSEALDY
LQALGFKVNPERRRCANIDEVIAFVNEWHEKRPQLPYEIDGIVIKVDSFAQQRELGATAK
SPRWAIAYKFPAEEVVTTLIGIEVNVGRTGVVTPTAILEPVRVAGTTVQRATLHNEDFIR
EKDIRIGDAVIIKKAGDIIPEVVGVVVDRRDGDETPFVMPTHCPECESELVRLDGEVALR
CLNPKCPAQLRERLIHFASRAAMNIEGLGEKVVTQLFNAGLVHDVADLYRLTKEQLIGLE
RMGEKSATNLLAAIEASKQNSLERLLFGLGIRYVGAKAAQLLAEHFETMERLEKATKEEL
MAVPEIGEKMADSIIAFFSQPEAAELLHELRLYGVNMAYKGPKRAAEAPADSAFAGKTVV
LTGKLASMSRNEAKEEIERLGGRVTGSVSRSTDIVIAGEDAGSKLEKAQQLGIEIWDESR
FLQEISRGKR
NT seq 2013 nt   +upstreamnt  +downstreamnt
atggaccgccaacaagccgaacggcgcgcggccgagctgcgcgaactgctgcaccgctat
ggctacgaatattatgtgctcgaccggccgtccgtcccggacgccgagtatgaccggctc
atgcaagagttgatggccatcgaggaacagtatccggaattgaaaacgagcgactcgccg
acccagcgcatcggcggccctccgcttgaggcgtttcgcaaagtgacgcatgttgttccc
atgatgagtctcgcgaacgcgtttgacgaaggggatttgcgtgattttgaccgccgcgtc
cgccaagaggtcggcgaagcagcgtacgtatgcgagttgaaaatcgatggcctcgccgtc
tccgtccgctatgaagacggttatttcgtccaaggggcgacgcgcggcgacggaacgacc
ggcgaggacattacggaaaatttgagaacgatccgttcactgccgcttcggctgaaggag
ccggtgtcgctggaggcgcgcggcgaggcgttcatgccgaaagcgtcgtttttgcgcttg
aatgaggagcgaaaagcccgaggcgaggagctgtttgccaacccgcgcaacgctgcggct
ggctcgctccgccagctcgacccgaaagtggcggcgtcgcgccagctcgatttgtacgtt
tatggtttggccaatgccgaagagcttggcattgagtcgcacagcgaggcgctcgactac
ttacaggcgcttgggtttaaagtgaatcccgagcggcggcgctgcgccaacatcgatgag
gtgatcgccttcgtcaacgagtggcacgaaaaacggccgcagctgccgtacgagatcgac
ggcatcgtcattaaagtcgactcgttcgcccaacagcgggagcttggtgcgacggcaaaa
agcccgcgctgggcgatcgcctacaaattcccagccgaggaagtggtgacgacgctcatc
ggcattgaggtgaacgtcggccgcacgggcgtcgtcactccgacagcgattcttgagccg
gtccgcgtcgccggcacgaccgtgcagcgcgccactcttcataatgaagattttatacgg
gaaaaagacattcgcatcggcgatgcggtcatcattaaaaaagcgggcgacatcatcccg
gaagtggtcggcgtcgtcgtcgaccggcgcgacggggatgaaacgccgtttgtgatgccg
acgcattgtccggaatgcgaaagcgagctcgtccgcctagatggagaagtggcgctccgt
tgcttaaacccgaaatgcccggcccagctgcgcgaacggctcatccattttgcctcaaga
gcagcgatgaacattgaagggttgggcgaaaaagtcgtcacccaactgtttaacgctggc
ctcgtccacgatgtcgccgatttgtaccggctgacgaaagaacagctcatcggtttggaa
cggatgggcgaaaagtcagcaaccaacttgcttgcagcgattgaggcatcgaagcaaaac
tcgctcgagcggttgctgttcggccttggcatccgctacgtcggagcgaaagccgcccaa
cttttggctgagcattttgaaacgatggagcggctggaaaaagcgacgaaagaggaattg
atggccgtgccggaaattggcgagaaaatggcggactcgatcatcgccttcttttcccag
ccagaagcggccgagctgctccatgagctgcggctttacggcgtcaacatggcatacaaa
gggccgaagcgggcggctgaagcgcctgctgactccgccttcgccggcaaaacggtcgtc
ttgaccggcaaactcgcgtcgatgtcgcgcaatgaggcaaaagaagagattgaacggctc
ggcgggcgcgtcaccggcagcgtcagccgcagcaccgacatcgtcatcgccggtgaggac
gccggatcgaagctggagaaagcccagcagcttggcattgagatttgggacgaatcacga
tttttgcaagagatcagcagggggaaacgatga

DBGET integrated database retrieval system