Geotrypetes seraphini (Gaboon caecilian): 117347178
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Entry
117347178 CDS
T09159
Symbol
HSD11B1
Name
(RefSeq) 11-beta-hydroxysteroid dehydrogenase 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
gsh
Geotrypetes seraphini (Gaboon caecilian)
Pathway
gsh00140
Steroid hormone biosynthesis
gsh00980
Metabolism of xenobiotics by cytochrome P450
gsh01100
Metabolic pathways
Module
gsh_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
gsh00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
117347178 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
117347178 (HSD11B1)
Enzymes [BR:
gsh01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
117347178 (HSD11B1)
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GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
NAD_binding_2
DUF1776
Shikimate_DH
NmrA
2-Hacid_dh_C
Epimerase
Motif
Other DBs
NCBI-GeneID:
117347178
NCBI-ProteinID:
XP_033773613
UniProt:
A0A6P8PFX7
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All DBs
Position
13:5912687..5929913
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AA seq
299 aa
AA seq
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MALLSRKLLIPLLGLVLALYFYSGGDEFKPELLKGKRIIVTGASSGIGEQMAYHLAQMGS
HVLITARREEKLKKVVAKCLELGAPSAHYIAGSMDDMVFAKSVVKKAEKLFGGLDMLILN
HMGDSYYNFFNGKVDHVRKLMEINYLSFVTMTVEAFPMLKSTNGSIVVVSSIAGKIGQAF
VVPYSATKFALDGFFSSLRQEFILKNVNISITLCILSLINTDTAVNAVGDVLRMPAAPQE
ECALEIIKGGALRLREVYYKYELTKIPILFRDWVPELLDSIMRSGFIVENLKNDSSLFS
NT seq
900 nt
NT seq
+upstream
nt +downstream
nt
atggctctgttgtcccgaaagcttctcattcccctgctgggacttgttctggccttgtac
ttctactcaggtggtgatgagttcaaaccagagctgctgaaagggaagcggatcattgtc
actggtgccagctctggaattggtgagcagatggcatatcacctggcccagatgggctcc
catgttctgataacagcacgaagagaggaaaagcttaaaaaggtcgtggcaaagtgttta
gagctgggagctccatccgctcactatatcgcaggaagcatggatgacatggtctttgcc
aagagtgtggtgaaaaaggctgaaaagctattcggtggtctggacatgctgatcctcaac
cacatgggagattcttactacaatttctttaatggaaaggttgaccacgtacggaagctc
atggagattaattatctcagctttgtgaccatgacagtagaggcttttcccatgttgaag
agcaccaatgggagcatcgttgtggtctcttcaattgcagggaaaattggtcaagcattt
gtcgttccgtactctgcaactaagtttgccctagatggatttttcagctccttgaggcag
gaatttatcctgaagaatgtcaatatctccataacattatgcattctcagcttaatcaat
acagacacagctgtgaatgctgtgggggatgtgctccgtatgccagcagcaccccaggag
gagtgcgctctagagatcatcaaaggaggagcccttcgccttcgggaggtttactacaag
tatgagttgactaaaatcccgatcttgtttcgtgactgggttccagagctcctggactca
ataatgaggagcggtttcattgtggaaaacctcaaaaatgatagcagcttattttcataa
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