Geotrypetes seraphini (Gaboon caecilian): 117354054
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Entry
117354054 CDS
T09159
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
gsh
Geotrypetes seraphini (Gaboon caecilian)
Pathway
gsh04012
ErbB signaling pathway
gsh04148
Efferocytosis
gsh04370
VEGF signaling pathway
gsh04510
Focal adhesion
gsh04810
Regulation of actin cytoskeleton
gsh05100
Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:
gsh00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
117354054 (PTK2)
04370 VEGF signaling pathway
117354054 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
117354054 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
117354054 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
117354054 (PTK2)
09160 Human Diseases
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
117354054 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gsh01001
]
117354054 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
gsh01009
]
117354054 (PTK2)
Enzymes [BR:
gsh01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
117354054 (PTK2)
Protein kinases [BR:
gsh01001
]
Non-receptor tyrosine kinases
FAK family
117354054 (PTK2)
Protein phosphatases and associated proteins [BR:
gsh01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
117354054 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Haspin_kinase
Kinase-like
FERM_F2
Motif
Other DBs
NCBI-GeneID:
117354054
NCBI-ProteinID:
XP_033786725
UniProt:
A0A6P8QJ12
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All DBs
Position
2:21895186..22674358
Genome browser
AA seq
1115 aa
AA seq
DB search
MLLELEGQVGLKQAGAICMEKKGCSPFPICWSKEYDGHLASRKNMATAYLDPNLNHTPVS
SAKSRLSTGMERSPGAMERVLKVFHFFETNSEPTTWASIIRHGDATDVRGIIQKIVDSHK
VKNVACYGLRLSHLSSEEIYWLHMDMGVSHVREKYELGHPAEEWKYELRVRYLPKGFLNQ
FTEDKPTLNFFYQQVKNDYMLEIADQVDQEIALKLGCLEIRRSYGEMRGNALEKKSNYEV
LEKDVGLKRFFPKSLLESVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGSNPTHLTDFNQVQTIQYSASEDKDKKGML
QLKIAGAPEPLTVTAPSLTIAENMADLVDGYCRLVNGATDSFIIRPLKEGERALPSIPKL
TNNEKQGVRTHTVSVSGFPPSYYGHGDEISGDETDDYAEIIDEEDTYTMPSTRDYEIQRD
RIELGRCIGEGQFGDVHQGVYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDH
AHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK
RFVHRDIAARNVLVSSTDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFT
SASDVWMFGVCKWEILMYGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA
YDPSRRPRFTELKAQLSTILEEERQQQEERMRMESRRQVTVSWDSGGSDEAPPKPSRPGY
PSPRSSEGFYPSPQHVVQPNHYQVSGYPGSHSIPSMQGSIYPGQTSVLDHPDSWNHRTQD
ISVWQPSMEDSGPLDIRGLGQVLPTHLMEERLIRQQQEMEDDQRWLEKEERFLKPDVRLS
RGSIDREDGALQGPAGNQHIYHPVGKPDHPAPPKKPPRPGAPSHLGSLASLNSPVDSYNE
GVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPDEYVPMVKGV
GLALRTLLATVDETIPVLPASMHREIEMAQKLLNSDLAELINKMKLAQQYVMTSLQQEYK
KQMLTAAHALAVDAKNLLDVIDQARLKMIGQSRPH
NT seq
3348 nt
NT seq
+upstream
nt +downstream
nt
atgttgttggaactggaaggccaagtgggcctgaaacaagcaggtgctatctgtatggag
aaaaaggggtgtagccctttcccaatatgctggtctaaagaatatgacggacacctagca
tctagaaaaaatatggccactgcttaccttgatccaaacttaaaccatacaccagtctct
agtgcaaaatcacgccttagtactggtatggaacgatccccaggcgctatggaacgtgta
ttgaaagtctttcatttttttgaaactaacagtgagccaacaacttgggctagtattatt
cgacatggagatgctactgatgtcaggggtataattcagaagatagtagatagccacaaa
gtgaagaatgtggcttgttatgggttgcgtctcagtcatctctcttcggaggagatttat
tggctgcacatggacatgggcgtatcgcatgtgagggagaaatacgaactaggtcatcca
gcagaggaatggaaatatgaacttagagtacgctacctaccaaaaggatttttaaaccag
ttcactgaggataaaccaacattaaatttcttctaccaacaggtaaaaaatgattacatg
ttagaaatagcagatcaggtggaccaagaaattgctttgaagttgggctgtctcgaaatt
cggagatcatatggggaaatgaggggaaatgcactagaaaagaagtccaactatgaagta
ttagagaaagatgttggattgaaacgatttttcccaaagagtttattggagtctgtcaag
gccaaaacactgcgaaaactgatccaacaaacgtttcgacaatttgctaaccttaacaga
gaagaaagtattttaaaattcttcgaaattctttcgcctgtgtatagatttgataaggag
tgcttcaaatgtgctcttggatcaagctggattatttccgtggagctagcaattgggcct
gaagaaggaattagctaccttactgacaaaggctctaatcctactcatttaacagacttc
aatcaggttcagactattcagtattcagctagtgaagacaaggacaaaaaaggaatgctg
cagctcaaaattgcaggtgctcctgagcctctcacagtgacagcaccatccttaaccatt
gctgagaatatggctgacttagtagatggatattgtcggttggtgaatggagctacagac
tcatttattatcaggcccctgaaagaaggtgaaagagcgttgccgtctataccaaagctg
accaacaacgaaaagcagggagtaagaacacacacagtgtctgtgtcaggtttccctcca
tcatactatggacatggagatgaaattagtggggacgaaacagatgactatgcagaaata
atagatgaggaagatacctacactatgccctctaccagggattatgagattcagagggac
agaattgaactgggacgctgcattggtgaaggacagtttggtgatgtacatcaaggagtt
tacatgagtcctgaaaacccagctttggctgttgcaattaaaacatgtaaaaactgcact
tctgacagcgtgagagaaaagttcctgcaggaagctttaactatgcgccagtttgatcac
gcacacattgtgaagctgattggagttataacagaaaatccagtgtggataatcatggaa
ctctgcacacttggcgagctccgttcatttttgcaagtaagaaagtacagtttggatcta
gcatctttgattctctatgcttaccagctcagcacagcacttgcctacctggagagcaaa
agatttgtgcatagggatatcgctgctagaaatgtattggtttcatcaactgattgtgtg
aaactaggagactttggtttgtcccggtatatggaagacagcacatactacaaagcttcc
aaagggaaattgcctatcaaatggatggctccagaatcaataaattttaggcgttttacc
tcagctagtgatgtatggatgtttggtgtttgtaagtgggaaattttaatgtatggtgtg
aagccttttcaaggcgtgaagaacaatgatgtgattggtcgaattgagaatggtgagcgg
ttaccaatgcctccaaactgtcctcccaccctctacagcctcatgacaaagtgttgggct
tatgaccccagcagaagaccaagattcactgaacttaaagcacaacttagtacaatactg
gaagaagagaggcaacagcaggaagagcgaatgagaatggaatcaagacgacaggtcaca
gtatcttgggattctggaggatctgatgaagctccccctaagcccagcagaccaggttat
cccagtccaagatcaagtgaaggtttttatccaagtcctcaacatgtagtacagcccaac
cattaccaggtttctggctatcctggttctcatagcattccatccatgcaaggtagtata
tatccagggcaaacatctgttttagatcatccggattcctggaatcatcggactcaggat
atttcagtgtggcaacccagtatggaggattcaggacccttggatattcgaggattgggt
caggttctaccaacacatttgatggaggaaagattaataagacaacaacaagaaatggaa
gatgatcagcgctggcttgaaaaagaggagagattcctgaaacccgatgtgaggctttcc
agaggcagcatcgacagagaagacggcgctctccaaggcccagctggtaaccagcatata
taccatcctgtgggaaaaccagatcatccagctccaccaaagaaaccacctcggcctgga
gcccccagccatcttggtagtttggccagtcttaacagtcctgttgacagctacaatgaa
ggagtaaagccatggcggcttcagccccaagaaattagccctccccctactgccaatttg
gatcgttccaatgacaaagtatatgagaatgtaactggattggtgaaagctgtcattgaa
atgtccagtaagatccagccagcacctccagatgaatatgtacccatggtgaagggtgtt
ggtctggctctaagaacattattggcaacagtagatgaaaccattccagtacttccagca
agcatgcacagagagattgagatggcacagaagctgttgaactctgatttggctgagctg
atcaacaaaatgaaattagcacagcagtatgtaatgaccagtctccaacaggaatacaaa
aaacagatgcttacagctgctcatgctttggccgtagatgccaaaaacttactggatgtt
attgaccaagctagactgaaaatgattgggcagtcaagaccacattaa
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