Geobacillus thermodenitrificans: GTNG_0621
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Entry
GTNG_0621 CDS
T00496
Symbol
metH
Name
(GenBank) 5-methyltetrahydrofolate S-homocysteine methyltransferase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
gtn
Geobacillus thermodenitrificans
Pathway
gtn00270
Cysteine and methionine metabolism
gtn00450
Selenocompound metabolism
gtn00670
One carbon pool by folate
gtn01100
Metabolic pathways
gtn01110
Biosynthesis of secondary metabolites
gtn01230
Biosynthesis of amino acids
gtn04980
Cobalamin transport and metabolism
gtn04981
Folate transport and metabolism
Module
gtn_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
gtn00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
GTNG_0621 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
GTNG_0621 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
GTNG_0621 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
GTNG_0621 (metH)
04980 Cobalamin transport and metabolism
GTNG_0621 (metH)
Enzymes [BR:
gtn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
GTNG_0621 (metH)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Met_synt_B12
Pterin_bind
B12-binding
B12-binding_2
CdhD
His_biosynth
Motif
Other DBs
NCBI-ProteinID:
ABO66003
UniProt:
A4IKZ9
LinkDB
All DBs
Position
complement(691246..694656)
Genome browser
AA seq
1136 aa
AA seq
DB search
MANITLEQQLQRKILVIDGAMGTMIQSANLSASDFGGEAYEGCNEYLTLTAPHVIRHIHE
AYLEAGADIIETNTFGATRIVLDEYGLGHLALELNIEAAKLAKQAAELFSTPDWPRFVAG
SMGPTTKTLSVTGGATFDELVTAYEEQARGLLLGGVDLLLLETCQDTLNVKAGFIGISKA
FEAVGRRVPLMISGTIEPMGTTLAGQAIDSFFISIRHMNPIAVGLNCATGPEFMTDHLRT
LSTLADTAVSCYPNAGLPDEEGHYHETPDMLAEKIRRFAEKGWINIVGGCCGTTPDHIRA
IAEAVRDLPPRVIPSSFDIHAVSGIEALMYDETMRPLFVGERTNVIGSRKFKRLIAEGKY
EEAAEIARAQVKNGAHVIDICLADPDRDERYDMEQFVRHVIKKVKVPLVIDSTDERVIEC
ALTYSQGKAIINSINLEDGEERFAKIAPLLHQYGAAVVVGTIDEQGMAITAERKLEIALR
SYDLLVNRYGVPAQDIIFDPLVFPVGTGDEQYIGAAKETIEGIRLIKERLPDCLTMLGIS
NVSFGLPPAGREVLNSVFLYHCTQAGLDYAIVNTEKLERFASIPENEVRMAEALLFDTSD
ETLNAFIEFYRSKITTAKPVETNLSLEERLARYVIEGSKDGLIPDLEQALETYSDPLSII
NGPLMAGMDEVGRLFNNNQLIVAEVLQSAEVMKAAVAFLEPYMEKKEGSTKGKVLLATVK
GDVHDIGKNLVDIILSNNGYEVVDLGIKVAPQQLIEAARQHEPDIIGLSGLLVKSAQQMV
VTAQDLRQAGISTPILVGGAALTRKFTENKIAPEYDGIVLYAKDAMDGLALANQIQQGTI
DYMKKERVENEPARAVGAATAVKSNVSTDVPVYIPADLDRHVLRDVPLGHVLPYVNWQMV
LGHHLGLKGKVKRLLEEKDEKALALKAVVDELLAEVQERGWIQPAGVYRFFPAQSDGNRV
YIYDPVDRQTVLETFDFPRQPRAPFLCLADYLKSKESGEIDYVGFFAVTAGGGIRELAQR
WKDEGEFLKSHAIQALALEIAEGFAERIHQIMRDRWGFPDDPDFTMEERFAAKYQGQRYS
FGYPACPNLEDQEKLFRLLHPEDIGIRLTDGYMMEPEASVSAIVFAHPEARYFNVL
NT seq
3411 nt
NT seq
+upstream
nt +downstream
nt
atggctaacatcaccttagaacagcaactacagcgaaaaattcttgtcatcgacggcgcc
atggggacgatgatccaaagcgccaacctatcagcatctgattttggcggcgaggcgtac
gaagggtgcaacgaatatttgaccctcaccgccccgcatgtcatccgccatattcatgaa
gcgtacttggaagctggcgccgacataatcgaaacgaacacgttcggggcaacacgcatc
gtgcttgacgaatacggccttgggcatttagcgctcgaactgaacatcgaggccgcgaaa
ctggcgaaacaagcggccgaattgttctcgacgccggactggccgcgttttgtcgccggc
tcgatgggaccgacgacaaagacgttatcagtgacgggcggagcgacgtttgacgaactt
gttaccgcctatgaagaacaggcacgcggactattgttaggcggtgtcgaccttctactt
ttggaaacgtgccaagatacactgaacgtcaaagcgggattcatcggcatttccaaagcg
tttgaagccgtcggccgccgcgtaccgcttatgatttctggaacgattgaaccgatgggc
acgacgcttgccgggcaggcgatcgattcgtttttcatctccatccgccatatgaatccg
atcgctgtcggcttaaactgcgcgaccggtccggaatttatgaccgaccatttgcgcacg
ctctccacgctcgccgacacagcggtcagctgctatccaaatgctggtctgccggacgaa
gaagggcattaccatgaaacgccggacatgttggcagagaaaattcgccgttttgctgaa
aaaggctggatcaacattgtcggcggttgttgcggcacgacaccggaccatattcgcgcc
attgccgaagcggtgcgcgatcttccgccgcgagtcatcccgtcttcgtttgacatacac
gctgtctccggcatcgaggcgctcatgtacgatgaaacgatgcgcccgctctttgtcggc
gaacggacgaacgtcatcggctcgcgcaaatttaagcgtctcatcgccgaaggcaagtac
gaagaggcggcagaaatcgcccgcgcccaagtaaaaaacggtgctcatgtcatcgacatt
tgccttgccgacccagaccgcgacgaacggtacgatatggaacaattcgtccgccacgtg
atcaaaaaagtgaaagtgccgcttgtcatcgactcgaccgatgagcgcgtcatcgagtgc
gctctcacctattcgcaagggaaagcgatcatcaactcgatcaacctcgaagacggcgaa
gagcggtttgcgaaaatcgcaccgctgcttcaccaatacggcgctgccgttgtcgtcggg
acgatcgatgaacaagggatggccatcaccgccgaacgaaagcttgagatcgccttgcgc
tcgtatgacttgctcgtgaaccgctacggcgttccggcgcaagacatcattttcgacccg
cttgtttttccagtcggcaccggtgatgagcagtacatcggtgcagcaaaagaaacgatc
gaaggcatccgtctcattaaagagcggctgcctgactgtttaacgatgctcggcatcagc
aacgtctcgttcggcttgccgccagccgggcgcgaagtgctaaactctgtctttttatac
cattgcacacaagctggtttggattatgccatcgtcaacaccgagaagcttgagcgattc
gcctcgattccagaaaacgaagtgcggatggccgaggcgctcctgtttgacacaagtgac
gaaacgttaaatgcatttatcgaattttaccgaagcaaaatcacaaccgccaaaccggta
gagacgaacttgagcttggaagagcgactcgcccgctacgtcatcgagggatcgaaagac
gggcttattcctgatttggaacaagcacttgaaacgtactccgacccgctgtcgatcatc
aacggcccgctcatggccggcatggacgaagtcggacggttgttcaacaacaaccagctc
atcgtcgccgaagtcctacaaagtgcggaagtgatgaaagcggctgtcgcctttttagaa
ccatatatggaaaagaaagaaggaagcacaaaaggaaaagtgctgcttgccactgtcaaa
ggtgatgtgcatgacatcggtaaaaacttagtcgacattattttaagcaacaatggctac
gaggtggtcgatcttggcattaaagtcgccccgcagcaactgatcgaggcggcgcgccaa
cacgagccagacattatcgggctatcaggcttgcttgtcaaatccgcccaacagatggtc
gttaccgcccaagatttgcgtcaagccggcatttcgaccccgattttagtcggcggcgcc
gctttgacgcgcaagtttacagaaaacaaaatcgcgccggaatatgatggcatcgtcttg
tacgcgaaagacgccatggacgggcttgcccttgccaaccaaatccaacaaggtacgatc
gattatatgaaaaaagaaagggtagagaacgaaccggcacgggcggttggtgccgccaca
gctgtcaaatccaacgtctcgaccgatgtcccggtctatatcccagccgacctcgaccgc
cacgtgctgcgtgatgtaccgcttgggcacgtgttgccgtacgtcaactggcaaatggtg
ctcggccatcatctcggtttgaaaggaaaagtgaagcggctgttagaagaaaaagacgaa
aaagcgctcgccttaaaagcagttgtcgatgaattgctcgctgaagtgcaggagcgcggc
tggattcagcccgcaggcgtctatcgctttttcccggcacaaagcgacggtaaccgcgtt
tatatttacgatcctgtcgaccggcaaaccgtgcttgagacgtttgacttcccgcgccag
ccgcgggcgccgttcctttgtcttgccgattatttgaaatcaaaagaaagtggggaaatc
gactatgtcggcttctttgctgtcaccgccgggggcggcatccgtgaactcgcccagcgc
tggaaagacgaaggcgaatttttgaaaagccatgctatccaagcattggcgctcgagatc
gccgaagggttcgctgaacgcatccaccaaattatgcgcgaccgttggggcttcccggat
gacccggacttcacgatggaagagcgcttcgccgccaaataccaaggccagcgctactcg
ttcggctatccggcctgcccgaacttggaagatcaagaaaaactgttccgtctccttcac
ccggaagatatcggtatccgtctaactgacggctatatgatggagccggaagcatctgtc
tcagcaattgtcttcgcccatccggaagcaaggtatttcaatgtgttataa
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