KEGG   Galeopterus variegatus (Sunda flying lemur): 103585463
Entry
103585463         CDS       T08727                                 
Symbol
PIK3R3
Name
(RefSeq) LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
gvr  Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr01521  EGFR tyrosine kinase inhibitor resistance
gvr01522  Endocrine resistance
gvr01524  Platinum drug resistance
gvr04012  ErbB signaling pathway
gvr04014  Ras signaling pathway
gvr04015  Rap1 signaling pathway
gvr04024  cAMP signaling pathway
gvr04062  Chemokine signaling pathway
gvr04066  HIF-1 signaling pathway
gvr04068  FoxO signaling pathway
gvr04070  Phosphatidylinositol signaling system
gvr04071  Sphingolipid signaling pathway
gvr04072  Phospholipase D signaling pathway
gvr04081  Hormone signaling
gvr04140  Autophagy - animal
gvr04150  mTOR signaling pathway
gvr04151  PI3K-Akt signaling pathway
gvr04152  AMPK signaling pathway
gvr04210  Apoptosis
gvr04211  Longevity regulating pathway
gvr04213  Longevity regulating pathway - multiple species
gvr04218  Cellular senescence
gvr04360  Axon guidance
gvr04370  VEGF signaling pathway
gvr04380  Osteoclast differentiation
gvr04510  Focal adhesion
gvr04550  Signaling pathways regulating pluripotency of stem cells
gvr04611  Platelet activation
gvr04613  Neutrophil extracellular trap formation
gvr04620  Toll-like receptor signaling pathway
gvr04625  C-type lectin receptor signaling pathway
gvr04630  JAK-STAT signaling pathway
gvr04650  Natural killer cell mediated cytotoxicity
gvr04660  T cell receptor signaling pathway
gvr04662  B cell receptor signaling pathway
gvr04664  Fc epsilon RI signaling pathway
gvr04666  Fc gamma R-mediated phagocytosis
gvr04668  TNF signaling pathway
gvr04670  Leukocyte transendothelial migration
gvr04722  Neurotrophin signaling pathway
gvr04725  Cholinergic synapse
gvr04750  Inflammatory mediator regulation of TRP channels
gvr04810  Regulation of actin cytoskeleton
gvr04910  Insulin signaling pathway
gvr04914  Progesterone-mediated oocyte maturation
gvr04915  Estrogen signaling pathway
gvr04917  Prolactin signaling pathway
gvr04919  Thyroid hormone signaling pathway
gvr04923  Regulation of lipolysis in adipocytes
gvr04926  Relaxin signaling pathway
gvr04929  GnRH secretion
gvr04930  Type II diabetes mellitus
gvr04931  Insulin resistance
gvr04932  Non-alcoholic fatty liver disease
gvr04933  AGE-RAGE signaling pathway in diabetic complications
gvr04935  Growth hormone synthesis, secretion and action
gvr04960  Aldosterone-regulated sodium reabsorption
gvr04973  Carbohydrate digestion and absorption
gvr05010  Alzheimer disease
gvr05017  Spinocerebellar ataxia
gvr05020  Prion disease
gvr05100  Bacterial invasion of epithelial cells
gvr05135  Yersinia infection
gvr05142  Chagas disease
gvr05146  Amoebiasis
gvr05160  Hepatitis C
gvr05161  Hepatitis B
gvr05162  Measles
gvr05163  Human cytomegalovirus infection
gvr05164  Influenza A
gvr05165  Human papillomavirus infection
gvr05166  Human T-cell leukemia virus 1 infection
gvr05167  Kaposi sarcoma-associated herpesvirus infection
gvr05168  Herpes simplex virus 1 infection
gvr05169  Epstein-Barr virus infection
gvr05170  Human immunodeficiency virus 1 infection
gvr05171  Coronavirus disease - COVID-19
gvr05200  Pathways in cancer
gvr05203  Viral carcinogenesis
gvr05205  Proteoglycans in cancer
gvr05206  MicroRNAs in cancer
gvr05207  Chemical carcinogenesis - receptor activation
gvr05208  Chemical carcinogenesis - reactive oxygen species
gvr05210  Colorectal cancer
gvr05211  Renal cell carcinoma
gvr05212  Pancreatic cancer
gvr05213  Endometrial cancer
gvr05214  Glioma
gvr05215  Prostate cancer
gvr05218  Melanoma
gvr05220  Chronic myeloid leukemia
gvr05221  Acute myeloid leukemia
gvr05222  Small cell lung cancer
gvr05223  Non-small cell lung cancer
gvr05224  Breast cancer
gvr05225  Hepatocellular carcinoma
gvr05226  Gastric cancer
gvr05230  Central carbon metabolism in cancer
gvr05231  Choline metabolism in cancer
gvr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
gvr05415  Diabetic cardiomyopathy
gvr05417  Lipid and atherosclerosis
gvr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:gvr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    103585463 (PIK3R3)
   04014 Ras signaling pathway
    103585463 (PIK3R3)
   04015 Rap1 signaling pathway
    103585463 (PIK3R3)
   04370 VEGF signaling pathway
    103585463 (PIK3R3)
   04630 JAK-STAT signaling pathway
    103585463 (PIK3R3)
   04668 TNF signaling pathway
    103585463 (PIK3R3)
   04066 HIF-1 signaling pathway
    103585463 (PIK3R3)
   04068 FoxO signaling pathway
    103585463 (PIK3R3)
   04070 Phosphatidylinositol signaling system
    103585463 (PIK3R3)
   04072 Phospholipase D signaling pathway
    103585463 (PIK3R3)
   04071 Sphingolipid signaling pathway
    103585463 (PIK3R3)
   04024 cAMP signaling pathway
    103585463 (PIK3R3)
   04151 PI3K-Akt signaling pathway
    103585463 (PIK3R3)
   04152 AMPK signaling pathway
    103585463 (PIK3R3)
   04150 mTOR signaling pathway
    103585463 (PIK3R3)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    103585463 (PIK3R3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103585463 (PIK3R3)
  09143 Cell growth and death
   04210 Apoptosis
    103585463 (PIK3R3)
   04218 Cellular senescence
    103585463 (PIK3R3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103585463 (PIK3R3)
   04550 Signaling pathways regulating pluripotency of stem cells
    103585463 (PIK3R3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103585463 (PIK3R3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103585463 (PIK3R3)
   04613 Neutrophil extracellular trap formation
    103585463 (PIK3R3)
   04620 Toll-like receptor signaling pathway
    103585463 (PIK3R3)
   04625 C-type lectin receptor signaling pathway
    103585463 (PIK3R3)
   04650 Natural killer cell mediated cytotoxicity
    103585463 (PIK3R3)
   04660 T cell receptor signaling pathway
    103585463 (PIK3R3)
   04662 B cell receptor signaling pathway
    103585463 (PIK3R3)
   04664 Fc epsilon RI signaling pathway
    103585463 (PIK3R3)
   04666 Fc gamma R-mediated phagocytosis
    103585463 (PIK3R3)
   04670 Leukocyte transendothelial migration
    103585463 (PIK3R3)
   04062 Chemokine signaling pathway
    103585463 (PIK3R3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103585463 (PIK3R3)
   04923 Regulation of lipolysis in adipocytes
    103585463 (PIK3R3)
   04929 GnRH secretion
    103585463 (PIK3R3)
   04915 Estrogen signaling pathway
    103585463 (PIK3R3)
   04914 Progesterone-mediated oocyte maturation
    103585463 (PIK3R3)
   04917 Prolactin signaling pathway
    103585463 (PIK3R3)
   04926 Relaxin signaling pathway
    103585463 (PIK3R3)
   04935 Growth hormone synthesis, secretion and action
    103585463 (PIK3R3)
   04919 Thyroid hormone signaling pathway
    103585463 (PIK3R3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    103585463 (PIK3R3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    103585463 (PIK3R3)
  09156 Nervous system
   04725 Cholinergic synapse
    103585463 (PIK3R3)
   04722 Neurotrophin signaling pathway
    103585463 (PIK3R3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103585463 (PIK3R3)
  09158 Development and regeneration
   04360 Axon guidance
    103585463 (PIK3R3)
   04380 Osteoclast differentiation
    103585463 (PIK3R3)
  09149 Aging
   04211 Longevity regulating pathway
    103585463 (PIK3R3)
   04213 Longevity regulating pathway - multiple species
    103585463 (PIK3R3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103585463 (PIK3R3)
   05206 MicroRNAs in cancer
    103585463 (PIK3R3)
   05205 Proteoglycans in cancer
    103585463 (PIK3R3)
   05207 Chemical carcinogenesis - receptor activation
    103585463 (PIK3R3)
   05208 Chemical carcinogenesis - reactive oxygen species
    103585463 (PIK3R3)
   05203 Viral carcinogenesis
    103585463 (PIK3R3)
   05230 Central carbon metabolism in cancer
    103585463 (PIK3R3)
   05231 Choline metabolism in cancer
    103585463 (PIK3R3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103585463 (PIK3R3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103585463 (PIK3R3)
   05212 Pancreatic cancer
    103585463 (PIK3R3)
   05225 Hepatocellular carcinoma
    103585463 (PIK3R3)
   05226 Gastric cancer
    103585463 (PIK3R3)
   05214 Glioma
    103585463 (PIK3R3)
   05221 Acute myeloid leukemia
    103585463 (PIK3R3)
   05220 Chronic myeloid leukemia
    103585463 (PIK3R3)
   05218 Melanoma
    103585463 (PIK3R3)
   05211 Renal cell carcinoma
    103585463 (PIK3R3)
   05215 Prostate cancer
    103585463 (PIK3R3)
   05213 Endometrial cancer
    103585463 (PIK3R3)
   05224 Breast cancer
    103585463 (PIK3R3)
   05222 Small cell lung cancer
    103585463 (PIK3R3)
   05223 Non-small cell lung cancer
    103585463 (PIK3R3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103585463 (PIK3R3)
   05170 Human immunodeficiency virus 1 infection
    103585463 (PIK3R3)
   05161 Hepatitis B
    103585463 (PIK3R3)
   05160 Hepatitis C
    103585463 (PIK3R3)
   05171 Coronavirus disease - COVID-19
    103585463 (PIK3R3)
   05164 Influenza A
    103585463 (PIK3R3)
   05162 Measles
    103585463 (PIK3R3)
   05168 Herpes simplex virus 1 infection
    103585463 (PIK3R3)
   05163 Human cytomegalovirus infection
    103585463 (PIK3R3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103585463 (PIK3R3)
   05169 Epstein-Barr virus infection
    103585463 (PIK3R3)
   05165 Human papillomavirus infection
    103585463 (PIK3R3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    103585463 (PIK3R3)
   05100 Bacterial invasion of epithelial cells
    103585463 (PIK3R3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    103585463 (PIK3R3)
   05142 Chagas disease
    103585463 (PIK3R3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103585463 (PIK3R3)
   05017 Spinocerebellar ataxia
    103585463 (PIK3R3)
   05020 Prion disease
    103585463 (PIK3R3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103585463 (PIK3R3)
   05418 Fluid shear stress and atherosclerosis
    103585463 (PIK3R3)
   05415 Diabetic cardiomyopathy
    103585463 (PIK3R3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    103585463 (PIK3R3)
   04932 Non-alcoholic fatty liver disease
    103585463 (PIK3R3)
   04931 Insulin resistance
    103585463 (PIK3R3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103585463 (PIK3R3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103585463 (PIK3R3)
   01524 Platinum drug resistance
    103585463 (PIK3R3)
   01522 Endocrine resistance
    103585463 (PIK3R3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:gvr04131]
    103585463 (PIK3R3)
Membrane trafficking [BR:gvr04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    103585463 (PIK3R3)
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 SH2_1 Transcrip_act
Other DBs
NCBI-GeneID: 103585463
NCBI-ProteinID: XP_008564658
LinkDB
Position
Unknown
AA seq 482 aa
MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVTNGMKDSSVTL
QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKN
LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
IERFRREGNEKEIERIMINYDKLKSRLGEIHDSKMRLEQDLKKQALDNREIDKKMNSIKP
DLIQLRKIRDQHLVWLNHKGVRQKRLNAWLGIKNEDADETYFINEEDENLPHYNEKTWFV
EDINRVQAEDLLYGKPDGSFLIRESSKKGCYACSVVADGEVKHCVIYNTARGYGFAEPYN
LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSFCRXRGSGKRGGSPAFFSTVFI
RL
NT seq 1449 nt   +upstreamnt  +downstreamnt
atgtacaatacggtgtggagtatggaccgcgatgacgcagactggagggaggtgatgatg
ccctattcgacagaactgatattttatattgaaatggatcctccagctcttccaccaaag
ccacctaagccaatgacttcagcagttacaaatggaatgaaggacagctctgttactctt
caggatgcagaatggtactggggggatatttcaagggaggaagtaaatgacaaattacgg
gacatgccagatggtactttcttggttcgagatgcctcaacaaaaatgcagggagattat
actttgactttgcggaagggaggcaataataagttaataaagatttatcatcgggatggt
aaatatggcttttctgatcctctgacatttaattctgtggtggagctcattaaccactat
catcatgaatctcttgctcagtacaatcccaaacttgatgtgaagctgatgtacccagtg
tccagataccaacaggatcagttggtaaaagaagataacattgatgcagtaggtaaaaac
ttgcaggagtaccactctcagtatcaggaaaagagtaaagagtatgataggctatatgaa
gaatataccagaacatcccaggaaatacagatgaagagaactgcaattgaagcttttaat
gaaacaattaaaatatttgaggagcagtgtcacacacaagaacaacatagcaaagaatat
attgagcgatttcgcagagaaggaaatgaaaaggagattgaacgaattatgataaattat
gataaattgaaatcacgtctgggtgagattcatgacagcaaaatgcgtctagagcaggat
ttgaagaaacaagctttggacaaccgggaaatagataaaaaaatgaatagtatcaaacct
gacctgattcagctgcgcaagatccgagatcagcaccttgtatggctcaatcacaaagga
gtgagacagaaacgcctgaatgcctggctgggaatcaagaatgaggatgctgatgagacc
tattttatcaatgaggaagatgaaaacctgccccattacaatgagaaaacctggtttgtt
gaggatatcaatcgagtacaagcagaggatttgctttatgggaaacctgacggttcattc
ttaattcgtgaaagtagcaagaaaggatgctatgcttgctctgtggttgctgatggggaa
gtgaagcactgtgtgatctacaacactgctcgcggctacggctttgcagagccctacaac
ttgtacagctcactgaaggagctggtgctccattaccagcagacatccttggttcagcac
aatgactccctcaacgtcaggcttgcctaccctgtccatgcacagatgccctcgttctgc
agataaagagggagtgggaaaagaggtggctctccagcattcttttctacagtttttatt
agactatga

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