Galeopterus variegatus (Sunda flying lemur): 103589303
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Entry
103589303 CDS
T08727
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr04120
Ubiquitin mediated proteolysis
gvr04144
Endocytosis
gvr04330
Notch signaling pathway
gvr04668
TNF signaling pathway
gvr04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
103589303 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
103589303 (ITCH)
04668 TNF signaling pathway
103589303 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
103589303 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
103589303 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
gvr04131
]
103589303 (ITCH)
04121 Ubiquitin system [BR:
gvr04121
]
103589303 (ITCH)
Enzymes [BR:
gvr01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
103589303 (ITCH)
Membrane trafficking [BR:
gvr04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
103589303 (ITCH)
Ubiquitin system [BR:
gvr04121
]
Ubiquitin ligases (E3)
HECT type E3
103589303 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
103589303
NCBI-ProteinID:
XP_008569471
LinkDB
All DBs
Position
Unknown
AA seq
859 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCSNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLVGDKEPTDTIGDLSICLDGLQLDSEVVTNGETTFSESASQNDDGSRPKDETRMNTNGS
DDPEDAGSGENRRVNGSNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNTNTSEGAASGLIIPLTISGGSGPRPLNPITQAPLPPGLHKIAATRLR
RVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDLF
ATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEM
RFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQQLAMPQ
HIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLN
PMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKR
ILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKPNGGN
ILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQ
EIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLM
GSNGPQKFCIEKVGKENWLPRSHTWEASVTGSYRLLPLLFVSGKLQFVYTVEWVEKTRKI
YSGEIGFGTYVEDDVGRDH
NT seq
2580 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacaacttggttcaatgggtagtctgaccatgaaatcacaactt
cagatcactgtcatctcagcaaaacttaaagaaaataaaaagaattggtttggtccaagt
ccttatgtggaagtcacagtagatggacagtcaaagaagactgaaaaatgcagtaataca
aacagtcccaaatggaagcaacctcttacagttatcgttacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacgctgaaatctgatgttttgttgggaactgctgcatta
gatatttatgaaacattaaagtcaaacaatatgaaacttgaggaagtggttgtgactttg
cagcttgtaggtgacaaagagccaacagatactataggagatttgtcaatttgtcttgat
gggctgcagttagactctgaagttgttactaatggtgaaactacattttcagaaagtgct
tcccagaatgatgatggctccagacccaaggatgaaacaagaatgaacacaaatggatca
gatgaccctgaggatgcagggtctggtgaaaacaggagagtcaatgggagtaattctccg
tcactctcaaatggcggttttaaaccttctaggcctccgagaccttcacgaccacctcca
cccaccccacgtagacctgcatctgtcaatggttcaccatctgccacttctgaaagtgat
ggatctagtacaggctctctaccaccaacaaatacaaatacaaatacatctgaaggagca
gcatccggattaataattcctctcactatatctggaggctcaggccctaggccattaaat
cctataactcaagctcccctcccacctggtcttcacaaaattgcagcgacaagattaagg
cgggttgacaacatgggacgtatttattatgttgaccatttcacaagaacaacaacatgg
cagaggccaacgctggaatccgtccggaactatgaacagtggcagctacaacgtagtcaa
cttcaaggagcaatgcagcagtttaaccagcgattcatttatgggaatcaagatttgttt
gctacatcacaaaataaagaatttgatccccttggtcctttgccacctggatgggagaag
agaacggacagcaatggtagagtatactttgtcaaccacaacactcgaattacgcaatgg
gaagaccccagaagtcaaggtcaattaaatgaaaagcccttacctgaaggctgggaaatg
agattcacagtggacggaattccatattttgtggaccacaatagaagaacaaccacctat
atagatccccgcacaggaaaatctgccctagacaatggaccccagatagcctatgttcgg
gacttcaaggcaaaggttcagtatttccggttctggtgtcagcaactggctatgccacag
cacataaagattacagtaacaagaaaaacattgtttgaggattcctttcaacagataatg
agcttcagtccccaagatctgcgaagacgtttgtgggtgatttttccaggagaagaaggt
ttagattatggaggtgtagcaagagaatggttctttcttttgtcacatgaagtgttgaac
ccaatgtattgcctgtttgaatatgcaggaaaggataactactgcttgcagataaacccc
gcttcttatatcaatccagatcacctgaaatactttcgttttattggcagatttattgcc
atggctctgttccatgggaaattcatagacacgggtttttctttaccattctataagcgt
atcttgaacaaaccagttggactcaaggatttagaatctattgatccagaattttacaat
tctctcatctgggttaaagaaaacaatattgaggaatgtggtttggaaatgtacttctcc
gttgataaagaaatcctaggtgaaattaagagtcatgacttgaaacccaatggtggcaat
attcttgtaacagaagaaaataaagaggaatacatcagaatggtagctgaatggaggttg
tctcgaggtgttgaagaacagacacaagctttctttgagggctttaatgaaatacttccg
cagcagtatttgcaatactttgatgcaaaggaattagaggtccttttatgtggaatgcaa
gaaattgacttgaatgactggcaaagacatgccatctaccgtcattacactaggacgagc
aagcagattatgtggttttggcagttcgttaaagaaatcgataatgagaagagaatgaga
cttctgcagtttgttactggaacctgccgattaccagtaggaggatttgctgacctcatg
gggagcaatggaccacagaaattctgcattgaaaaagttgggaaagaaaattggttgccc
agaagtcatacctgggaagcctctgtgactgggtcatatagacttctgccactgcttttt
gtaagtggcaaattacagtttgtctatactgtggagtgggtagaaaaaactagaaagatc
tactcaggtgagattggatttggtacctatgttgaagatgatgtcggcagggaccactga
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