Galeopterus variegatus (Sunda flying lemur): 103593677
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Entry
103593677 CDS
T08727
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr04062
Chemokine signaling pathway
gvr04151
PI3K-Akt signaling pathway
gvr04217
Necroptosis
gvr04550
Signaling pathways regulating pluripotency of stem cells
gvr04630
JAK-STAT signaling pathway
gvr04658
Th1 and Th2 cell differentiation
gvr04659
Th17 cell differentiation
gvr05161
Hepatitis B
gvr05162
Measles
gvr05166
Human T-cell leukemia virus 1 infection
gvr05169
Epstein-Barr virus infection
gvr05200
Pathways in cancer
gvr05203
Viral carcinogenesis
gvr05223
Non-small cell lung cancer
gvr05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
103593677 (JAK3)
04151 PI3K-Akt signaling pathway
103593677 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
103593677 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
103593677 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
103593677 (JAK3)
04659 Th17 cell differentiation
103593677 (JAK3)
04062 Chemokine signaling pathway
103593677 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103593677 (JAK3)
05203 Viral carcinogenesis
103593677 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
103593677 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103593677 (JAK3)
05161 Hepatitis B
103593677 (JAK3)
05162 Measles
103593677 (JAK3)
05169 Epstein-Barr virus infection
103593677 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
103593677 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gvr01001
]
103593677 (JAK3)
Enzymes [BR:
gvr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
103593677 (JAK3)
Protein kinases [BR:
gvr01001
]
Non-receptor tyrosine kinases
JAK family [OT]
103593677 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
Kinase-like
Kdo
ABC1
FERM_M
LRR_RI_capping
FERM_C_FAK1
SH2
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
103593677
NCBI-ProteinID:
XP_008574928
LinkDB
All DBs
Position
Unknown
AA seq
1104 aa
AA seq
DB search
MAPPSEETPLISQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVRAAKA
SSILPVYHSLFALAAEDLSCWFPPSHIFSVEDVGTQVLVYRLRFYFPNWLGLEKCHRFGL
RKDLASSILDLSVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQR
PAELLKTVSYKACLPPGLRDLIQGLSFVTRRRIRRTVSRALRRVASCQADRHSLMAKYIM
DLERLDPAGAAETFRVGLPGAAGGQDRPGLLRVAGDSGIAWSPGGQEILQPFCDFPEIVD
ISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHYFC
KEVAPPRLLEEVAEQCHGPITLDFAIDKLKTGGSLPGSYVLRRSPQDFDSFLLTVCVQTS
LGPDYKGCLIRRDPTGGFSLVGLSRPHSSLRELLAACWDGGLHIDGVTLNLTSCCTPRPK
EMSNLLVVRRGCSPSTSSPVQPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR
HEAVDGEARKTEVLLKVMDATHKNCTESFLEAASLMSQVSYQHLVLLHGVCMAGDSTMVQ
EFVHLGAIDTYLRKRGHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGA
DGSPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEAQMLGLEADKWGFGATVWEVFS
GVTMPISTLDPAKKLQFYEKRQQLPAPKWTELALLIQQCMAYEPGQRPSFRAVIRDLNSL
ITSDYELLSDPSPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR
YDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL
VMEYLPSGCLRDFLQRHRARLDASRLLLYASQICKGMEYLGSRRCVHRDLAARNILVENE
AHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL
FTYSDKSCSPSAEFLRMMGCERDAPALCRLLELLAEGQRLPAPPACPGEVHELMKLCWAP
NPQDRPSFSTLGPQLDALWSGSQG
NT seq
3315 nt
NT seq
+upstream
nt +downstream
nt
atggctcctccaagtgaagagacgcccctgatctctcagcgctcctgcagcctttcatcc
tcggaggctggcgccctgcatgtgctgctgcctcctcggggccctgggcccccccagcgc
ctatctttctcttttggggaccactcggcagaggaactgtgtgtgcgggctgccaaggcc
agcagcatcctgcccgtctaccattccctctttgctctggctgcggaggacctgtcctgc
tggtttcccccgagccacatcttctccgtggaggacgtgggcacccaagtcctggtgtac
aggctccggttttacttccccaactggttggggctggagaaatgccaccgcttcgggctc
cgcaaggatctggccagctccatccttgacttgtcagtcctggagcacctctttgcccag
caccgcagcgacctggtgagcgggcggctccccgtgggcctcagcctcaaggagcagggt
gagtgtctcagcctggcggttctggacttggcccggatggcccgtgagcaggcccagcgg
cccgcggagctgctgaagactgtcagttacaaggcctgcctgccccccggcctgcgcgac
ttgatccagggcctgagcttcgtgacgcgcaggcgtatccgaaggacagtgagccgcgcc
ctgcgccgcgtggcctcctgccaggccgaccggcactcgctcatggccaagtacatcatg
gacctggagcggctggatccggctggggccgctgagaccttccgcgtaggcctgccaggg
gctgctggtggccaggaccggccggggttgctccgcgtggctggtgacagcggaatcgcc
tggagcccgggaggacaggagatcctccagcccttctgcgactttccagaaatcgtggac
atcagcatcaagcaggccccgcgcgttggcccggctggggagcaccggctggtcactgtc
accaggacagacaaccagatcctggaggccgagttccctgggctgcccgaagcgctgtcc
ttcgtggcgctcgtggacggctacttccggctgaccaccgactctcagcactacttttgc
aaggaggtggcgccgccgcggctgctggaggaggtggccgagcagtgccatggccccatc
acactggactttgccatcgacaagcttaagactgggggctcacttcctggctcctacgtt
ctccgccgcagcccccaggacttcgacagcttccttctcactgtctgtgtccagacctcc
cttggccctgattacaagggctgcctcattcggcgtgaccccacgggaggcttctccctg
gttggcctcagccggccccacagtagtcttcgagagctcctggcagcctgctgggatggt
gggctgcacatagatggggtcacactgaacctcacctcctgctgcacccccagacctaaa
gaaatgtccaatctgcttgtggtccggaggggttgcagcccatccacgtcatctcctgtt
cagccccagtctcaatgccagctgagtcagatgacgttccataagatccccgctgacagc
ctggagtggcatgagaatctgggccatgggtccttcaccaagatttaccggggctgtcgc
cacgaagctgtggatggagaggcccgcaagaccgaggtgctgctgaaggttatggacgcc
acacacaaaaactgcacagagtcgttcctggaagcagcgagtttgatgagccaagtttcg
taccagcatctcgtgttgctccatggcgtgtgcatggccggagacagcaccatggtgcag
gaatttgtacacctgggagcaatagacacatatctgcgcaagcgtggccacctggtgcca
gccagctggaagctgcaggtggtcaaacagctggcctatgccctcaactatctggaggac
aaaggcctcccccatggcaatgtctcagctcggaaggtgctcctggctcgggagggggct
gatgggagcccaccctttatcaagctgagtgaccctggggtcagccctactgtgctgagc
ttggagatgctcaccgacaggatcccctgggtggcccctgagtgtcttcaggaggcccag
atgcttggcttggaagctgacaagtggggctttggtgccacggtctgggaggtgttcagc
ggagtcaccatgcccatcagcaccctggatcccgccaagaaactccagttttacgagaaa
cggcagcagctgccagcccccaagtggacagagctggccttgctgatccaacagtgcatg
gcctatgagccgggccagaggccatccttccgagctgtcatccgggacctcaacagcctc
atcacgtcagattatgagctcctttccgacccctcgccgggtgccctggcaccccgtgac
ggcctgtggaatggcgcacagctctatgcctgccaggaccccacgatcttcgaggagaga
cacctcaagtacatctcgcagctgggcaagggcaactttggcagtgtggagctgtgccgg
tatgacccactgggcgacaacacaggcgctctggtggccgtgaagcagctgcagcacagc
gggccagaccagcagagagacttccagagggaaatccagatcctcaaagcgctgcacagt
gactttatcgtcaagtaccgcggtgtcagctacggcccgggccgtcagagcctgcggctt
gtcatggagtacctgcccagcgggtgcctgcgcgacttcctgcagcggcatcgcgcgcgc
ctcgacgccagccgcctcctgctttacgcctctcagatttgcaagggcatggagtacctg
ggctcccgccgctgcgtgcaccgcgacctggccgcccggaacatcctcgtggagaatgag
gcgcatgtcaagatcgccgactttggcctagccaagctgctgcccctggacaaagactac
tacgtggtccgcgagccgggccagagccccatcttctggtacgcccccgagtccctgtca
gacaacatcttctcgcgccagtcagatgtctggagcttcggggtcgtcctgtacgagctc
ttcacctacagcgacaaaagctgcagcccctcggccgagttcttgcggatgatgggatgc
gagcgagacgcccccgccctctgccgcctcctggagctgttggccgagggccagaggctg
ccggcacctcctgcctgccccggtgaggttcacgagctcatgaagctgtgctgggcccct
aacccacaggaccggccatcattcagcaccttgggccctcagctggatgcactgtggagt
gggagccaggggtag
DBGET
integrated database retrieval system
