Galeopterus variegatus (Sunda flying lemur): 103594929
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Entry
103594929 CDS
T08727
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck isoform X1
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr04064
NF-kappa B signaling pathway
gvr04380
Osteoclast differentiation
gvr04517
IgSF CAM signaling
gvr04650
Natural killer cell mediated cytotoxicity
gvr04658
Th1 and Th2 cell differentiation
gvr04659
Th17 cell differentiation
gvr04660
T cell receptor signaling pathway
gvr05135
Yersinia infection
gvr05166
Human T-cell leukemia virus 1 infection
gvr05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
gvr05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
103594929 (LCK)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
103594929 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
103594929 (LCK)
04660 T cell receptor signaling pathway
103594929 (LCK)
04658 Th1 and Th2 cell differentiation
103594929 (LCK)
04659 Th17 cell differentiation
103594929 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
103594929 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103594929 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103594929 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
103594929 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
103594929 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gvr01001
]
103594929 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
gvr03036
]
103594929 (LCK)
Enzymes [BR:
gvr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
103594929 (LCK)
Protein kinases [BR:
gvr01001
]
Non-receptor tyrosine kinases
SRC family
103594929 (LCK)
Chromosome and associated proteins [BR:
gvr03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
103594929 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
SH2_1
Haspin_kinase
Kdo
DUF7251
SH3_16
SH3_3
Motif
Other DBs
NCBI-GeneID:
103594929
NCBI-ProteinID:
XP_008576441
UniProt:
A0ABM0R750
LinkDB
All DBs
Position
Unknown
AA seq
520 aa
AA seq
DB search
MWAWELTISGNMGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKATLPIRNGSDVRDPLV
TYQGSNPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEG
FIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRD
FDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKP
QKPWWEDEWEVPRETLKLVERLGSGQFGEVWMGYYNGHTKVAVKSLKQGSMSPNAFLAEA
NLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPAGIKLTINKLLDMAAQIA
EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP
EAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVQPDNCPEEL
YHLMMLCWKERPEDRPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgtgggcctgggagctgacaatctcagggaacatgggctgtagctgcagctcaaaccct
gaagatgactggatggagaacatcgatgtgtgtgagaactgccactaccccatagtccca
ctggatggcaaggccacgctgcccatccggaatggctctgacgtgcgggacccactggtc
acctaccagggctccaatccccctgcctccccactgcaagataatctggttatcgcgctg
cacagctatgagccctctcacgacggagacctgggcttcgagaagggagaacaactccgc
atcctggagcagagcggcgagtggtggaaggcgcagtccctaacaacgggccaggaaggc
ttcatccccttcaacttcgtggccaaagcgaacagcctggagcccgaaccctggttcttc
aagaacctgagccgcaaggacgcggagcggcagctcctggctcccgggaacacgcacggc
tccttcctgatccgggagagcgagagcaccgcgggatcgttttcactgtcggtccgggac
ttcgaccagaaccagggagaggtggtgaaacattacaagatccgtaacctggacaacggc
ggcttctacatctcccctcgcatcacttttcccggcctgcacgaactggtccgccactac
accaatgcttcggatgggctgtgtacgcgactgagccgcccgtgccagacccagaagccc
cagaagccttggtgggaggacgagtgggaggttcccagggagacgctgaagctggtggag
cggctggggagcggccagttcggggaggtgtggatggggtactacaatgggcacacgaaa
gtggcggtgaagagcctgaagcagggaagcatgtcccccaacgccttcctggctgaggcc
aacctaatgaagcaactgcaacaccagcggctggtccggctttacgcggtggtcacccag
gagcccatctacatcatcaccgaatacatggagaacggaagcctggtggattttctcaag
acccccgcaggcatcaaattgaccatcaacaaactcttggacatggcagcccaaattgca
gagggcatggcattcatcgaagagcggaattatatccaccgtgacctgcgggctgccaac
atcctggtgtctgacaccctgagctgcaagattgctgactttggtctcgcacgcctcatt
gaggacaatgagtacacagccagggagggggccaagtttcccattaagtggacagcacca
gaagccattaactacgggacattcaccatcaagtcggatgtgtggtcttttgggattctg
ctgacggagattgtcacccatggccgcatcccttacccagggatgaccaatcctgaggtg
attcagaacctggagcgtggctaccgcatggtgcaacctgacaactgtccagaggaactg
taccacctcatgatgctgtgctggaaagaacgccctgaggaccggcccacctttgactac
ctgcgcagtgtgctggaggacttcttcacggccacggagggccagtaccagccccagcct
tga
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