Galeopterus variegatus (Sunda flying lemur): 103607308
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Entry
103607308 CDS
T08727
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr00140
Steroid hormone biosynthesis
gvr01100
Metabolic pathways
gvr04913
Ovarian steroidogenesis
gvr04925
Aldosterone synthesis and secretion
gvr04927
Cortisol synthesis and secretion
gvr04934
Cushing syndrome
Module
gvr_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
gvr_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
gvr_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
gvr_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
103607308
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
103607308
04925 Aldosterone synthesis and secretion
103607308
04927 Cortisol synthesis and secretion
103607308
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103607308
Enzymes [BR:
gvr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
103607308
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
103607308
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Ortholog
Paralog
GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
Polysacc_synt_2
GDP_Man_Dehyd
NAD_binding_4
NAD_binding_10
NmrA
KR
Sacchrp_dh_NADP
adh_short
Motif
Other DBs
NCBI-GeneID:
103607308
NCBI-ProteinID:
XP_008590047
LinkDB
All DBs
Position
Unknown
AA seq
234 aa
AA seq
DB search
MTGWSCLVTGGGGFLGQRIVRLLVEEKELQEIRVLDKVFRPKVREEFSKLQNKTKLTVLE
GDILDEQCLKRACQGISVVIHTASIISVTDITYREAIINVNVKGTVARGDGARWENEDYD
TPHQSYDNLNYTLSREWGLSLDSRMSLPLSLKYWIAFLLEIVSFLLSPIYKYQPPFNRHL
VTLSNSVFTFTYKKAQRDLGYEPLFSWEEAKQKTTEWIGSLVEQHKETLKTKTQ
NT seq
705 nt
NT seq
+upstream
nt +downstream
nt
atgacaggatggagctgccttgtgacaggaggaggaggatttctgggtcagaggatcgtc
cgcttgttggtggaggagaaagagctgcaggaaatcagggtcctggacaaggtcttcaga
ccgaaagtgagggaggaattttctaagctccagaacaagaccaagctgacagtgctggaa
ggggacattctggatgagcagtgcctgaagagagcttgccagggcatctcggtcgtcatc
cacacggcctccatcatcagcgtcacagatatcacttacagagaggccatcataaatgtg
aatgtgaaaggtacagtagcccggggagatggagcaaggtgggaaaatgaggactatgac
acacctcaccaaagctatgataacttgaattacactctgagcagagaatggggccttagc
cttgattccagaatgagcctccctttatctctgaagtattggattgccttcctactggaa
atagtgagcttcctgctgagtccaatttacaaatatcaaccccctttcaaccgccactta
gtgacattgtcaaatagtgtgttcaccttcacctacaagaaagctcagcgagatctggga
tacgagcccctcttcagttgggaggaagccaagcagaaaaccacggagtggattggttcc
ctggtggagcagcacaaggagaccctgaaaaccaagactcagtaa
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