Halomonas sp. GFAJ-1: BB497_06805
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Entry
BB497_06805 CDS
T05375
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
hag
Halomonas sp. GFAJ-1
Pathway
hag00010
Glycolysis / Gluconeogenesis
hag00020
Citrate cycle (TCA cycle)
hag00620
Pyruvate metabolism
hag00785
Lipoic acid metabolism
hag01100
Metabolic pathways
hag01110
Biosynthesis of secondary metabolites
hag01120
Microbial metabolism in diverse environments
hag01200
Carbon metabolism
hag01210
2-Oxocarboxylic acid metabolism
Module
hag_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hag00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
BB497_06805
00020 Citrate cycle (TCA cycle)
BB497_06805
00620 Pyruvate metabolism
BB497_06805
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
BB497_06805
Enzymes [BR:
hag01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
BB497_06805
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AVI62434
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Position
1490718..1493390
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AA seq
890 aa
AA seq
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MSLETREDLDTVETTEWLDSLESVLDREGEDRARYLMTRLADRLRRDGMKVPFSVTTPHR
NTIPVHREAPMPGDLFMERRIRSLIRYNAIAQVIRNNRANPGLGGHIASFMSSATLYDVG
FNHFFRAAKDDFAGDLIYIQGHVAPGIYARSYLEGRLSEEQMDKFRREVDGDGLSSYPHP
WLMPDYWQFPTVSMGLGPIQAIYQAHVMKYLHHRELKDMHDRKIWCFMGDGECDEPESLG
AISLAGRENLDNLIFVINCNLQRLDGPVRGNSRVMDEFEGVFRGAGWNVIKVVWGRHWDP
LFEKDKKGVLQKRMDEAVDGEYQNYKANGGSYTREHFFGKYPETEEMVKDLSDEDIWKLN
RGGHDPFKVYAAYHEAVNQTNGKPTVILAHTVKGYGMGSGDGEAANEAHQVKSMEYEALR
KFRDRFGIPLTDEQLKDVPYYKPEEDSPELKYMHLQRERLNGYLPSRRSDFDALEIPALE
DKTFASQMGGSKGREVSTTMAFVRILNGLVKDKALGKLVVPIIPDEARTFGMEGMFRQLG
IYTAEGQKYEPVDKGQIMYYREDQKGQVLEEGITEAGAMSAWIAAATSYSNNHVTLLPFY
IYYSMFGFQRIGDLAWAAGDLQARGFMVGGTAGRTTLNGEGLQHQDGHSLIQASTIPNCR
SYDPTYAHEVAVIVQDGLKRMFTDKENCFYYLTVMNENYEHPALENVPADDIVKGMYLLN
ETQGDKGRVQLLGSGTILREVEAAAELLANDWGIGADIWSVTSFNELRREALLLEREAFL
NPDDEAAKPHVTKCLEGRDGPVIASTDYMKLYADQVRAWVPGDYTVLGTDGFGRSDTREK
LRYFFEVDRYFVTVAALKALADRGELDRKHVGEALKKYGIDANKPNPLTS
NT seq
2673 nt
NT seq
+upstream
nt +downstream
nt
atgagtctggagacaagagaagatctcgatacagtcgaaaccacggagtggctggactcc
ctggaatcggtactggatcgtgagggcgaagatcgtgcccgttacctgatgacccgcctg
gcggatcgcctgcgccgggatgggatgaaggtacccttctcggtgacgaccccgcaccgc
aacacgattccggttcaccgcgaagcgcccatgcctggcgatttgttcatggagcgtcgt
atccgctctttgattcgctacaacgccatcgcccaggtgattcgtaacaaccgcgctaac
ccgggtctgggtggccacattgccagcttcatgtcatcagcaacgctttatgacgttggc
tttaaccactttttccgcgccgctaaggatgactttgcgggcgacctgatttacatccag
gggcacgtggcgccgggcatctatgcgcgctcctacctggaagggcgcctgtcggaagag
cagatggacaagttccgccgcgaagttgacggcgatggcctctcctcgtacccgcacccg
tggctaatgccggactactggcagttccccaccgtctccatgggccttggccccattcag
gcgatctaccaagcccacgtgatgaagtacctgcatcaccgtgagctgaaagacatgcac
gaccgcaagatctggtgcttcatgggcgacggcgagtgcgacgagccggaatctctaggc
gcgatttccctggccggccgtgagaacctcgacaacctgatcttcgtgatcaactgtaac
ctgcagcgcctggacggcccggtccgcggtaactcccgcgtgatggacgagttcgaaggc
gtgttccgcggcgccggttggaacgtgatcaaggtggtctggggccgtcactgggacccg
ctgttcgagaaggacaaaaagggcgtcctgcaaaaacgcatggacgaagcggtcgacggc
gagtaccagaactacaaggccaacggcggctcctacacccgtgaacacttcttcggcaag
taccccgaaaccgaagaaatggtcaaagacctctccgatgaggatatctggaagctcaac
cgtggtggccacgacccgttcaaggtctacgcggcctaccatgaagcggttaaccagacc
aacggcaaacccacggtcattctggcgcacaccgttaaaggctacggtatgggcagcggc
gatggcgaagcagccaacgaagcgcaccaggttaaaagtatggagtacgaggcgctgcgt
aaattccgcgatcgctttggcattccgctcaccgatgaacagcttaaagacgtgccctac
tacaagccggaagaggactcccccgagcttaagtacatgcacctgcagcgtgagcgcttg
aatggctacctgccaagccgccgtagtgattttgacgcgctggaaataccggcccttgaa
gataaaacgtttgcctcgcaaatgggcggctccaaaggccgtgaagtctccaccaccatg
gcgtttgtgcggattctcaatggcttggtgaaggataaggcccttggcaagctggtcgtg
ccgatcatccctgatgaagcgcgtacttttggtatggaaggcatgttccgtcagttaggt
atttataccgctgaaggccagaagtatgagccggtggataaaggccagatcatgtactac
cgcgaggaccagaaaggtcaggtccttgaagagggtattactgaagcgggcgccatgtct
gcctggatcgctgcggcgacctcctacagcaacaaccacgtgacgctgctgccgttctac
atctactactcgatgtttggcttccagcgcattggtgatttggcctgggccgccggcgac
ctgcaggcccgtggctttatggtcggtggcactgccgggcgcaccacgctcaacggtgaa
ggcctgcagcaccaggatggtcacagcctgattcaggcatcgaccatccccaactgccgc
agctacgacccgacctatgctcatgaagtggcggttatcgttcaggatggtctgaagcgc
atgttcactgacaaagagaactgcttctactacctgacggtgatgaacgaaaactacgag
caccccgcactggaaaacgtacccgccgacgatatcgtcaaaggtatgtacctgctcaac
gaaacccagggtgacaaaggtcgcgttcaactgctgggctccggcactatcctgcgcgaa
gtcgaagcggccgccgagcttctggccaacgactggggcattggtgctgacatttggagc
gtcaccagctttaacgagctgcgccgcgaagcgctgctgctggagcgcgaagccttcttg
aaccccgatgacgaggccgccaagccccacgtcacgaagtgcctggaaggccgcgatggc
ccggtcattgcctccaccgactacatgaagctgtatgcggatcaggtgcgcgcttgggta
ccgggtgactacactgttttgggtaccgatggctttggtcgttcggatacccgcgagaag
ctgcgttacttcttcgaagttgaccgctacttcgtaacggtagcagcactgaaggcgctg
gctgatcgtggcgagcttgatcgcaagcacgtcggcgaggcgctgaagaagtacggcatt
gatgccaacaagcccaacccgctgaccagctaa
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