Hipposideros armiger (great roundleaf bat): 109389600
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Entry
109389600 CDS
T04661
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
hai
Hipposideros armiger (great roundleaf bat)
Pathway
hai04120
Ubiquitin mediated proteolysis
hai04144
Endocytosis
hai04330
Notch signaling pathway
hai04668
TNF signaling pathway
hai04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
hai00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
109389600 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
109389600 (ITCH)
04668 TNF signaling pathway
109389600 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
109389600 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
109389600 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hai04131
]
109389600 (ITCH)
04121 Ubiquitin system [BR:
hai04121
]
109389600 (ITCH)
Enzymes [BR:
hai01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
109389600 (ITCH)
Membrane trafficking [BR:
hai04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
109389600 (ITCH)
Ubiquitin system [BR:
hai04121
]
Ubiquitin ligases (E3)
HECT type E3
109389600 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
109389600
NCBI-ProteinID:
XP_019510821
UniProt:
A0A8B7SBY4
LinkDB
All DBs
Position
Unknown
AA seq
876 aa
AA seq
DB search
MVQRVCRPIGGMSDSGLELGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDG
QSKKTEKCNNTNSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSN
NMKLEEVVVTLQLVGDKEPTETIGDLSVCLDGLQLDSEVVTNGETTCSENVKGTSQNDDG
SRSKDETRVNTNGSDDPEDAGSGENRRVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRP
ASVNGSPSATSESDGSSTGSLPPTNANSNTSEAAASGLIIPLTISGGSGPRPLNPVPQAP
LPPGWEQRVDQHGRVYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQ
RPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEYDPLGPLPPGWEKR
TDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYI
DPRTGKSALDNGPQIAYVRDFKAKFQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMS
FSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPA
SYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNS
LIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLS
RGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHTIYRHYTRTSK
QIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPR
SHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2631 nt
NT seq
+upstream
nt +downstream
nt
atggtgcagagggtttgccgtcctattggtggtatgtctgacagtggattagagcttggt
tcaatgggtagcctgaccatgaaatcacaacttcagatcactgtcatttcagcaaaactt
aaagaaaataaaaagaattggtttggaccaagtccctacgtagaagtcacggtagatgga
cagtcaaagaagacagaaaaatgcaacaatacgaacagtcccaaatggaagcaacccctt
acagttatcgtcacccctgtgagtaaattacattttcgtgtgtggagtcaccagacactg
aaatctgatgttttgttgggaactgctgcattagatatctatgaaacattaaagtcaaac
aatatgaaacttgaggaagtggttgtgactttacagcttgtaggtgataaagagccaaca
gagactataggagacttgtcagtttgtcttgatgggctgcagttagactctgaagttgtt
acaaatggtgaaactacatgttcagaaaatgttaaaggtacttcacagaatgatgatggc
tccagatccaaggatgaaacaagagtgaacacaaatggatcagatgaccctgaggatgca
gggtctggtgaaaataggagggtcaatgggaataattctccatcactctcaaatggcggt
tttaaaccttctaggcctccaagaccttcacgaccacctccacctaccccacgtagacca
gcttctgtcaatggttcaccttctgccacttctgaaagtgatggatctagtacaggttct
ctgccaccaacaaatgcaaattcaaatacatctgaagcagcagcatctggattaataatt
cctcttacaatatctggaggctcaggccctaggccattgaatcctgtacctcaagctccc
ctaccacctggttgggagcagagagtggaccagcatgggcgagtttactatgtagatcat
attgagaaaagaacaacgtgggatagaccagagcctctacctcctgggtgggaacggcgg
gtcgacaacatgggacgtatttattatgttgaccatttcacaagaacaacaacgtggcag
aggccaacattggaatccgtccgtaactatgaacagtggcagctccaacgtagtcaactt
cagggcgcaatgcagcagtttaaccagagattcatttatggaaatcaagatttgtttgct
acatcacaaaataaagaatatgatccccttggccccctgccacctggatgggagaagaga
acagacagcaatggtagagtatattttgtcaaccacaacactcgtattacacaatgggag
gatcccagaagtcaaggtcagttaaatgaaaaacccttacctgaaggttgggaaatgaga
ttcacagtggatggaattccatattttgtggaccacaatagaagaacaacaacctatata
gatccccgaacaggaaaatctgccctagacaatggaccccagatagcctatgtacgggac
ttcaaagcaaagtttcagtatttccggttctggtgtcagcaactggccatgccacagcac
ataaagattacagtgacaagaaaaacattgtttgaggattcctttcagcagataatgagc
ttcagtccccaagatctgcgaagacgtttgtgggtgatttttccaggagaagaaggttta
gattatggaggtgtagcaagagaatggttctttcttttgtcacatgaggtgttgaaccca
atgtattgcctgtttgaatatgcagggaaggataactactgcttgcagataaaccctgct
tcttacatcaacccagatcacctgaaatattttcgttttattggaaggtttattgccatg
gctctgttccacgggaaattcatagacacaggcttttctttgccattctataagcgtatc
ttgaacaaaccagttggactcaaggatttagaatctattgatccagaattttacaattct
ctcatctgggttaaagaaaacaatattgaggaatgtggattggaaatgtacttctcagtc
gataaagaaattttaggtgaaatcaagagtcacgatttgaaacctaatggtggcaatatt
cttgtaacagaagaaaacaaagaagaatatatcagaatggtagctgaatggaggttgtcc
cgaggtgttgaagaacagacacaagctttctttgagggctttaatgaaattcttccccag
cagtatttgcaatacttcgatgcaaaggagttagaggtccttttatgtggaatgcaagag
attgatttgaatgactggcaaagacataccatctaccgtcattacactaggacaagcaaa
caaatcatgtggttttggcagtttgttaaagaaatcgataatgagaagagaatgagactt
ctacagtttgttactggaacctgccgattgccagttggaggatttgctgacctcatgggg
agcaatggaccacagaaattctgcattgaaaaagttgggaaagaaaattggttacccaga
agtcatacctgttttaaccgcctggacctgccaccctacaagagctatgagcaactgaaa
gaaaagctgttatttgccattgaagaaacagaaggatttggacaagagtaa
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