Hipposideros armiger (great roundleaf bat): 109395752
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Entry
109395752 CDS
T04661
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
hai
Hipposideros armiger (great roundleaf bat)
Pathway
hai01524
Platinum drug resistance
hai03440
Homologous recombination
hai03460
Fanconi anemia pathway
hai04120
Ubiquitin mediated proteolysis
hai04151
PI3K-Akt signaling pathway
hai05206
MicroRNAs in cancer
hai05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
hai00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
109395752 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
109395752 (BRCA1)
03460 Fanconi anemia pathway
109395752 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
109395752 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
109395752 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
109395752 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
109395752 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hai01009
]
109395752 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hai04121
]
109395752 (BRCA1)
03036 Chromosome and associated proteins [BR:
hai03036
]
109395752 (BRCA1)
03400 DNA repair and recombination proteins [BR:
hai03400
]
109395752 (BRCA1)
Enzymes [BR:
hai01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
109395752 (BRCA1)
Protein phosphatases and associated proteins [BR:
hai01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
109395752 (BRCA1)
Ubiquitin system [BR:
hai04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
109395752 (BRCA1)
Multi subunit type E3
BRCC complex
109395752 (BRCA1)
Chromosome and associated proteins [BR:
hai03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
109395752 (BRCA1)
DNA repair and recombination proteins [BR:
hai03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
109395752 (BRCA1)
BRCA1-A complex
109395752 (BRCA1)
BRCA1-B complex
109395752 (BRCA1)
BRCA1-C complex
109395752 (BRCA1)
BRCA complex
109395752 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
109395752 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-RING_2
zf-C3HC4_3
zf-RING_5
RING_XB3-XBAT31
zf-RING_6
BRCT_2
zf-ANAPC11
zf-Nse
zf-RING_10
zf-rbx1
Prok-RING_4
Baculo_IE-1
Motif
Other DBs
NCBI-GeneID:
109395752
NCBI-ProteinID:
XP_019522579
UniProt:
A0A8B7TBW5
LinkDB
All DBs
Position
Unknown
AA seq
754 aa
AA seq
DB search
MDLCVDRVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNDITKRSLQESTRFSQLVEELLKTIHAFELDTGLQFTNSYNFSKKEINSPEKLNE
DISIIQSLGYRNRVKRLRQSEPENPTLQETRLNVQLSNLEIVRSLRTKQQIQPQKKSVYI
ELGSDSSEDTVKENYFSVRDHELQITPQGARAEASLNPAKKDNAACEFSEAITNIKHHES
SNKDLTTTEKHATEKHPEKYQDDAAPEYEREACLSEDGSELSSQNVILTTQQKDTMQDNL
IKLQQEMAELEAVLEQHGSQTSNSSPSIIADSCASEDLLNPEQNMSEKAVLTSENSGKHL
ISQNPESLFADKFQESLDSSTNKSKEPGVERSFPSQSQLLDNGWHVGSHLPSLQNGNRPS
QVTDVEGQQLTQSEAQDLTERSDLPKQDLEGTPYLESEISLFSDDPEFDPSEDRAPEPAH
VCSMPTSTSALKLPQFQVEEPAKSPAAAHTTNTAEYNVREKSVSREKPEVISSAQRVNKR
ISMVASGLTPKEIALVRKFARKHHIVLTDLITEETTHVIMKTDVEFVCERTLKYFLGIAG
GKWVVSYFWVTQSTKERKILDECDFEVRGDVVNGRNHEGPKRARESQHRKIFRGLEICCY
GPFTNMPTDQLEWMVQLCGATVVKEPSLFTFGKGTYPVVVVQPDAWTEDSGLHAIGQVCE
APVVTREWVLDSVALYQCQELDTYLIPQISQSCC
NT seq
2265 nt
NT seq
+upstream
nt +downstream
nt
atggatttatgtgtggatcgcgttgaagaagtacaaaatgtccttaatgctatgcagaaa
atcttagagtgcccaatctgtctggagttgatcaaagagcctgtttccacaaaatgtgac
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccttcacag
tgtcctttgtgtaagaatgatataaccaaaagaagcctacaagaaagtacaagatttagt
caacttgttgaagagctattgaaaaccattcatgcttttgagcttgacacgggattgcag
tttacaaacagttataacttttcaaaaaaggaaattaactcccctgagaaactaaatgag
gacatttctatcatccaaagtttgggctaccgaaaccgtgtcaaaagacttcgacagagt
gaacctgaaaatcctaccttgcaggaaacgcgtcttaatgtccagctctctaaccttgaa
attgtgagatcactgaggacaaagcaacagatacaacctcagaagaagtctgtctacatt
gaattgggatccgattcttctgaagatacagttaaagaaaattatttcagtgtgagagat
cacgaattacaaatcacccctcaaggagccagggctgaagccagtttgaatcctgcaaaa
aaggataatgctgcttgtgagttttctgaggccataacaaatattaagcatcatgaatcc
agtaataaagatttgaccaccacagagaagcatgcaactgagaagcatccagaaaagtat
caggatgatgcagcacctgagtatgagcgtgaagcctgcctctctgaagatggttcagag
ctgtcctctcagaatgttattttaaccactcagcagaaggataccatgcaagataacctg
ataaagctccagcaggaaatggccgaactggaagcggtgttagagcagcatgggagtcag
acttctaacagctccccttccatcatagctgattcttgtgcctcagaggacttgctaaat
ccggaacaaaacatgtcagaaaaagcagtattaacgtcagagaacagtggtaaacatctt
attagtcagaatccagaaagcctttttgcagacaagtttcaagaatctctggatagttcc
accaataaaagtaaagaaccaggagtggaaaggtctttcccttctcaatcccagttgtta
gacaatgggtggcatgtgggcagccacttgccaagtcttcagaacggaaaccgcccgtct
caagttactgacgtggaggggcaacagctgacacagtcggaggcccaggatttaacggag
cggtctgatttgccaaaacaagatctagagggaaccccttacctagaatctgaaatcagc
ctcttctcggatgaccctgagtttgatccctctgaagacagagctccagagccggctcat
gtttgcagcatgccaacttcaacctctgccttgaaattaccccaatttcaagttgaagaa
cctgccaagagtccagctgctgctcatactactaatactgctgaatataatgtgagggag
aaaagcgtgagcagggagaagccagaagtgatatcttcagcacaaagagtcaacaaaaga
atatctatggtggcatcaggcttgaccccaaaagaaattgcgcttgtgcgcaagtttgcc
agaaaacaccacatcgttttaactgatctaattaccgaagagactactcatgtcattatg
aaaacagatgttgagtttgtatgtgaacggacactgaaatattttctgggaattgcagga
ggaaaatgggtagttagctatttctgggtgacccagtctacgaaagaaagaaagattcta
gatgagtgtgattttgaggtcagaggagatgttgtcaacggaaggaaccacgaaggtcca
aagcgagcaagagaatcccagcacagaaagatcttcaggggcctagaaatctgttgctat
gggccctttaccaacatgcctacagatcagctagagtggatggtgcagctctgtggggct
actgtggtgaaggagccttcgttgttcaccttcggcaagggtacttacccagttgtggtt
gtgcagccagatgcctggacagaggacagtggcctccatgcgattgggcaggtgtgtgag
gcacctgtggtgacccgagagtgggtattggacagcgtagccctctaccagtgccaggag
ctggacacctacctgataccccagatctcccagagctgctgctga
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