KEGG   Halioglobus maricola: EY643_10070
Entry
EY643_10070       CDS       T06250                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
halc  Halioglobus maricola
Pathway
halc00270  Cysteine and methionine metabolism
halc00450  Selenocompound metabolism
halc00670  One carbon pool by folate
halc01100  Metabolic pathways
halc01110  Biosynthesis of secondary metabolites
halc01230  Biosynthesis of amino acids
halc04980  Cobalamin transport and metabolism
halc04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:halc00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    EY643_10070 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    EY643_10070 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    EY643_10070 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    EY643_10070 (metH)
   04980 Cobalamin transport and metabolism
    EY643_10070 (metH)
Enzymes [BR:halc01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     EY643_10070 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding SUZ ComA
Other DBs
NCBI-ProteinID: QFU75981
UniProt: A0A5P9NJG9
LinkDB
Position
2231755..2235438
AA seq 1227 aa
MSSTPSNALLQALQQRILVIDGAMGTMIQAEGLEEKDYRGERFAEHGTDLKGNNDILCMT
RPDIVGKIHRAYLEAGADIIETCNFNATSIGQEDYNLGAVAYELNLASARVARKVADEVT
AETPDKPRFVAGVLGPTPKTASISPDVNDPGARSITFEQLRQSYLEATLALIEGDVDLIL
IETIFDTLNAKAAVFAVKDAFAQAGVELPIMISVTFPDVSGRVLSGQNPEAFYNAIAHAK
PLIVGSNCGRRYKEIRPFLEDLSNAAECYFSAHLNAGLPNAFGDFDETPEIMHEDFADFA
ERGFLNLAGGCCGTTPEHIRAISQAVADKAPRQIPQRSKAARLSGLEPFNITADSLFVNV
GERCNVTGSARFKRLVLEGDYETALDVARTQVEDGAQIIDVNMDEGMLDAKEAMVTFLNL
IASEPDIARVPIMVDSSKWEVIEAGLQCIAGKAIVNSISLKAGEEEFLEQARLCLKYGAA
VVVMAFDEDGQADNLERRKQICKRSYDLLVNDVGMSPNDIIFDPNIFAVATGIEEHNNYA
VDFIEGTRYIKQELPGALVSGGVSNVSFSFRGNNAVREAIHSVFLYHAIRAGMDMGIVNA
GQLAVYDELADDLREAVEDVVLNRREDGTERLLDIAERYRDSGGGAARVEDLSWREEDVA
KRLEYALVKGINTYIVEDAEAARQTFERPIQVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLQPYIEDAKESGNSSNGKILMATVKGDVHDIGKNIVGVVLQCNNFEVID
LGVMVPCEEILRVAKEEDVDIIGLSGLITPSLDEMVHVAAEMQRQEFDVPLLIGGATTSN
AHTAVKIDPQYDRDLVTYVPDASRSVSVATQLMGDGKASFVEERRENYEKVRERIANREP
RNRQLSYEAAIQRAPEIDWAGYQAPKPAFTGVRVFDDFPLQDLVDTIDWTPFFITWELAG
KFPAILEDDKVGEQASDLFRDAQAMLKRIVDEKLLTARAAIGFWPAQRKGADDVALYTDE
SRSTELATLHHMRQQTEKPGDKPNLSLADYVAPVDSGVADYVGGFCVTTGLGVDELAAQY
EADHDDYNSILLKALADRLAESFAEYLHRHVRTELWGYAPDEALANEDLIRERYQGIRPA
PGYPACPDHTEKATLFSLLEAEKNCGVKLSESYAMTPAASVSGFYYSHPDARYFAVGKIG
RDQLESIAARKGESVDTMERWLRPNLN
NT seq 3684 nt   +upstreamnt  +downstreamnt
atgagcagtacccctagcaatgccctcctccaggctctccagcagcgcatccttgttatc
gatggcgccatgggcaccatgattcaggctgaaggccttgaggaaaaggactatcgcggg
gagcgatttgccgagcacggtactgacctcaagggcaataacgacattctctgcatgact
cgcccggatatcgtcggcaagatccaccgcgcctacctcgaagctggcgcagatatcatc
gagacctgtaatttcaatgccacctcgatcggccaggaagactataacctgggcgctgtg
gcgtatgaattgaacctggcctccgcccgggtggcgcgcaaagtggcagacgaggtcact
gcagaaaccccggacaagccacgatttgtcgctggggtgcttggccctacaccaaagact
gcatcgatatcaccagacgttaacgacccgggtgcccgcagcattacctttgagcaactg
cgccagagctacctcgaagccacgctcgcactcattgaaggcgacgtcgatctgattctg
atcgaaaccatttttgacaccctgaacgcaaaagcggccgtgttcgcagtcaaagatgcg
ttcgcccaggctggcgtcgaactgcccatcatgatctcggtgacctttcccgacgtcagt
gggcgcgtattgtccggccagaaccccgaggccttctacaacgcgattgcccatgccaag
ccgcttatcgtcggcagcaactgtggccgccgctacaaggaaattcggccgttcctggag
gatctgtcgaacgccgccgaatgctacttcagtgcccacctgaatgccgggctcccaaac
gcctttggggacttcgacgaaacgcctgaaatcatgcatgaagacttcgcggattttgcc
gagcgtggatttctcaacctcgcgggcggttgctgcggcacaacgccggagcacattcgc
gccatcagccaggctgttgccgacaaagccccccgccagattccacagcgcagtaaagcc
gcgcgcctgagtggccttgagccctttaatattaccgctgacagcctgttcgttaacgtt
ggcgagcgctgtaacgtgaccggttctgcgcggtttaagcgcctggtccttgaaggtgac
tatgaaaccgcactggatgtggcgcgcacccaggttgaagacggcgcccagatcatcgat
gtgaacatggatgaaggcatgctcgatgccaaagaagccatggtcacgttcctcaatctc
atcgcgtccgaacccgatatcgcccgggtccccattatggtcgattcgtcgaagtgggaa
gtgatcgaggcagggctgcagtgtatcgcgggtaaggccattgttaattccatcagcctc
aaggctggcgaagaggaattcctggagcaagcgcgtctctgcctcaagtatggcgcggct
gtggtggtgatggcattcgacgaagacggtcaggccgacaacctggagcgtcgcaaacag
atctgtaagcgttcctacgatctgttggtcaacgatgtcggcatgtcgccgaacgacata
attttcgatcccaacatttttgctgtggctaccggtatcgaagagcacaacaattacgcg
gtggatttcatcgagggcacgcgctatatcaagcaggaactgcccggtgcgctagtctcc
ggcggagtctcgaacgtgtccttctcgttccgcggcaacaacgcggttcgcgaggctatt
cactcagtattcctgtaccacgctattcgcgcagggatggacatgggcatcgttaacgcg
ggccagttggcggtatatgacgagttggcagacgacctgcgagaggccgttgaagatgtg
gttctcaatcgccgcgaggatggaaccgaacgcctgctggatatcgcagagagatatcga
gacagtggcggtggcgcggctcgcgttgaagacctgagttggcgtgaggaagacgttgcg
aagcgcctggaatatgccctggtaaaaggcataaacacctacattgttgaagatgctgaa
gccgcgagacaaacattcgaacgcccgattcaggtgatcgaaggcccattgatggacggc
atgaatgtggtcggcgacctgtttggcgagggcaaaatgttcctgccacaagtcgtgaaa
agtgctcgcgtgatgaagcaggccgtcgcctacctgcagccctacattgaggatgccaaa
gagtccggcaattccagcaacggcaagattctcatggccacggtgaaaggcgacgtccat
gacatcggcaaaaatattgttggggtggtgcttcagtgtaacaattttgaagtgattgac
ctgggcgtaatggtgccctgtgaagaaattctgcgtgtagctaaggaagaagacgtcgac
atcatcggcctcagtggcctgatcacgccatcgctagacgaaatggtgcacgtcgcagca
gaaatgcagcgccaggaatttgacgttcccctgctcatcggtggcgccaccacatcgaac
gcccacaccgcggtaaaaatagacccgcaatatgatcgcgatctggttacctacgtgccc
gacgcatcgagaagtgtttccgtcgctacccaattgatgggtgatggcaaagccagcttt
gtagaagagcgtcgcgaaaactatgagaaagtccgtgagcgtattgcaaaccgcgagcct
cgcaaccgccagttaagttatgaagcggcgatacagcgcgctcccgaaatagactgggcg
ggataccaggccccgaagccggcgttcactggtgtgcgcgttttcgacgatttcccgctg
caagacctcgtagacactattgattggacgccctttttcatcacctgggaactcgccgga
aaatttcctgccattctcgaggacgacaaggtcggcgaacaggccagcgacctgttccgt
gatgcgcaagccatgctcaagcgcattgtcgatgaaaaactgctaaccgcacgtgccgct
attggcttctggccagcgcagcgcaaaggagcggatgatgtcgcactctataccgatgaa
agtcgttctaccgagctggcgacgctgcaccatatgcgccagcagaccgagaagcccggc
gacaaacccaacctgagcctggccgactatgtagcgcccgttgacagcggcgtcgcggac
tatgtgggcggcttttgcgtcaccactggccttggcgtagacgagctggctgcgcagtat
gaagctgaccacgatgactacaacagcattctgctgaaggccctggcagatcggctggct
gaatcctttgctgagtacctgcatcgccatgtacgcaccgaactatggggttacgcaccg
gatgaagcgctggccaacgaagacttgatccgcgagcgctaccagggaatacgccccgcc
cctggctaccccgcctgtcccgaccatactgaaaaagcgaccttgttcagtttgctggaa
gcggagaaaaattgtggtgtgaagctctccgagagctatgcgatgacgccggctgcctcc
gttagcggtttctactactcccatcccgacgcgcggtacttcgccgttggcaaaattggg
cgcgaccagcttgaaagtatcgccgcccgcaagggggaatcggtggacaccatggagcgc
tggttgcgccccaacctgaattaa

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