KEGG   Hyperoodon ampullatus (northern bottlenose whale): 307067082
Entry
307067082         CDS       T11951                                 
Symbol
MMP2
Name
(RefSeq) 72 kDa type IV collagenase
  KO
K01398  matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
Organism
hamp  Hyperoodon ampullatus (northern bottlenose whale)
Pathway
hamp01522  Endocrine resistance
hamp04670  Leukocyte transendothelial migration
hamp04912  GnRH signaling pathway
hamp04915  Estrogen signaling pathway
hamp04926  Relaxin signaling pathway
hamp04933  AGE-RAGE signaling pathway in diabetic complications
hamp05200  Pathways in cancer
hamp05205  Proteoglycans in cancer
hamp05219  Bladder cancer
hamp05415  Diabetic cardiomyopathy
hamp05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hamp00001]
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    307067082 (MMP2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    307067082 (MMP2)
   04915 Estrogen signaling pathway
    307067082 (MMP2)
   04926 Relaxin signaling pathway
    307067082 (MMP2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    307067082 (MMP2)
   05205 Proteoglycans in cancer
    307067082 (MMP2)
  09162 Cancer: specific types
   05219 Bladder cancer
    307067082 (MMP2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    307067082 (MMP2)
   05415 Diabetic cardiomyopathy
    307067082 (MMP2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    307067082 (MMP2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    307067082 (MMP2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hamp01002]
    307067082 (MMP2)
Enzymes [BR:hamp01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.24  gelatinase A
     307067082 (MMP2)
Peptidases and inhibitors [BR:hamp01002]
 Metallo peptidases
  Family M10
   307067082 (MMP2)
SSDB
Motif
Pfam: Peptidase_M10 fn2 Hemopexin PG_binding_1 Reprolysin_3 Reprolysin_5 Peptidase_M66
Other DBs
NCBI-GeneID: 307067082
NCBI-ProteinID: XP_079580496
LinkDB
Position
18:complement(30037697..30059879)
AA seq 584 aa
MQKFFGLPQTGELDQSTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLD
PETVDDAFARAFRVWSGVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFA
PGPGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYTSCTDTGRSDGF
LWCSTTYNFDRDGKYGFCPHEALFTMGGNADGQPCKFPFRFQGTSYDSCTTEGRTDGYRW
CGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKHESCTSAGRSDGKLWCA
TTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSEDPGALMAPIYTYTKNFRLSHD
DIKGIQELYGASPDIDIGTGPTPTLGPITPEICKQDIVFDGISQIRGEIFFFKDRFIWRT
VTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWVYSASTLERGYPKPL
TSLGLPPDVQKVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDN
LDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
NT seq 1755 nt   +upstreamnt  +downstreamnt
atgcagaagttcttcgggctaccccagacaggtgaactggaccagagcaccatcgagacc
atgcggaagccgcgctgcggcaaccccgacgtggccaactacaacttcttcccccgcaag
cccaagtgggacaagaaccagatcacctacaggatcatcggctacacccctgatctggac
cccgagacagtggacgacgccttcgctcgtgccttccgagtctggagtggtgtaactcca
ctgcggttttctcggatccatgatggagaagctgacatcatgatcaactttggccgctgg
gagcatggagatgggtacccttttgacggcaaagacgggcttctggctcacgccttcgcc
ccaggccctggcgttgggggagactctcactttgacgacgatgagctgtggaccctggga
gaagggcaagtggtccgcgtgaagtatgggaacgccgacggggagtactgcaagttcccc
ttcctgttcaacggcaaggagtacaccagctgcacggacacgggccgcagcgacggcttc
ctctggtgttccaccacctacaacttcgacagggacggcaagtacggcttctgcccccat
gaagccctgttcaccatgggtggcaacgccgacggacagccctgcaagttcccgttccgc
ttccagggtacatcctatgacagctgcaccacggagggccgtaccgatggctaccgctgg
tgtggcaccaccgaggactatgaccgcgacaagaagtacggcttctgccccgagaccgcc
atgtccactgtgggcgggaactcggaaggtgccccctgtgtcttccccttcaccttcctg
ggcaacaagcacgagagctgcaccagcgccggccgcagcgatgggaagttgtggtgtgcg
accacggccaactacgacgatgaccgcaagtggggcttctgccccgaccaagggtacagc
ctgttccttgtggcagcccatgagtttggccatgcaatggggctggagcactcagaggat
cccggagccctaatggcccccatttacacctacaccaagaacttccgcctgtcacatgat
gacatcaagggcattcaagagctctatggggcctcccctgacattgacattggcaccggc
cccacgcccacgctgggccccatcactcctgagatctgcaaacaggacatcgtctttgat
ggcatctctcagatccgtggggagatcttcttcttcaaggaccggttcatttggcgaaca
gtgacaccacgtgacaagcccatggggcccctgctggtggccacattctggcctgagctc
ccggaaaagatcgatgctgtatacgaggccccacaggaggagaaagctgtgttctttgca
gggaatgaatactgggtctattcagccagcaccctggagcgagggtaccccaagccactg
accagcctggggcttccccctgatgtccaaaaagtggatgctgcctttaactggagcaag
aacaagaagacatacatcttcgctggagacaagttctggagatacaatgaggtgaagaag
aaaatggatcctggcttccccaagctcatcgcagatgcctggaacgccatccctgataac
ctggatgccgtggtggacctgcagggcgggggtcacagctacttcttcaagggtgcgtat
tacctgaagttggagaaccaaagtctgaagagcgtgaagttcggaagcatcaagtccgac
tggctgggctgctga

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