KEGG   Hyperoodon ampullatus (northern bottlenose whale): 307068151
Entry
307068151         CDS       T11951                                 
Symbol
GRB2
Name
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
hamp  Hyperoodon ampullatus (northern bottlenose whale)
Pathway
hamp01521  EGFR tyrosine kinase inhibitor resistance
hamp01522  Endocrine resistance
hamp04010  MAPK signaling pathway
hamp04012  ErbB signaling pathway
hamp04014  Ras signaling pathway
hamp04062  Chemokine signaling pathway
hamp04068  FoxO signaling pathway
hamp04072  Phospholipase D signaling pathway
hamp04150  mTOR signaling pathway
hamp04151  PI3K-Akt signaling pathway
hamp04380  Osteoclast differentiation
hamp04510  Focal adhesion
hamp04517  IgSF CAM signaling
hamp04540  Gap junction
hamp04550  Signaling pathways regulating pluripotency of stem cells
hamp04630  JAK-STAT signaling pathway
hamp04650  Natural killer cell mediated cytotoxicity
hamp04660  T cell receptor signaling pathway
hamp04662  B cell receptor signaling pathway
hamp04664  Fc epsilon RI signaling pathway
hamp04714  Thermogenesis
hamp04722  Neurotrophin signaling pathway
hamp04910  Insulin signaling pathway
hamp04912  GnRH signaling pathway
hamp04915  Estrogen signaling pathway
hamp04917  Prolactin signaling pathway
hamp04926  Relaxin signaling pathway
hamp04935  Growth hormone synthesis, secretion and action
hamp05034  Alcoholism
hamp05160  Hepatitis C
hamp05161  Hepatitis B
hamp05163  Human cytomegalovirus infection
hamp05165  Human papillomavirus infection
hamp05200  Pathways in cancer
hamp05203  Viral carcinogenesis
hamp05205  Proteoglycans in cancer
hamp05206  MicroRNAs in cancer
hamp05207  Chemical carcinogenesis - receptor activation
hamp05208  Chemical carcinogenesis - reactive oxygen species
hamp05210  Colorectal cancer
hamp05211  Renal cell carcinoma
hamp05213  Endometrial cancer
hamp05214  Glioma
hamp05215  Prostate cancer
hamp05220  Chronic myeloid leukemia
hamp05221  Acute myeloid leukemia
hamp05223  Non-small cell lung cancer
hamp05224  Breast cancer
hamp05225  Hepatocellular carcinoma
hamp05226  Gastric cancer
hamp05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hamp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    307068151 (GRB2)
   04012 ErbB signaling pathway
    307068151 (GRB2)
   04014 Ras signaling pathway
    307068151 (GRB2)
   04630 JAK-STAT signaling pathway
    307068151 (GRB2)
   04068 FoxO signaling pathway
    307068151 (GRB2)
   04072 Phospholipase D signaling pathway
    307068151 (GRB2)
   04151 PI3K-Akt signaling pathway
    307068151 (GRB2)
   04150 mTOR signaling pathway
    307068151 (GRB2)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    307068151 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    307068151 (GRB2)
   04540 Gap junction
    307068151 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    307068151 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    307068151 (GRB2)
   04660 T cell receptor signaling pathway
    307068151 (GRB2)
   04662 B cell receptor signaling pathway
    307068151 (GRB2)
   04664 Fc epsilon RI signaling pathway
    307068151 (GRB2)
   04062 Chemokine signaling pathway
    307068151 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    307068151 (GRB2)
   04912 GnRH signaling pathway
    307068151 (GRB2)
   04915 Estrogen signaling pathway
    307068151 (GRB2)
   04917 Prolactin signaling pathway
    307068151 (GRB2)
   04926 Relaxin signaling pathway
    307068151 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    307068151 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    307068151 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    307068151 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    307068151 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    307068151 (GRB2)
   05206 MicroRNAs in cancer
    307068151 (GRB2)
   05205 Proteoglycans in cancer
    307068151 (GRB2)
   05207 Chemical carcinogenesis - receptor activation
    307068151 (GRB2)
   05208 Chemical carcinogenesis - reactive oxygen species
    307068151 (GRB2)
   05203 Viral carcinogenesis
    307068151 (GRB2)
   05231 Choline metabolism in cancer
    307068151 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    307068151 (GRB2)
   05225 Hepatocellular carcinoma
    307068151 (GRB2)
   05226 Gastric cancer
    307068151 (GRB2)
   05214 Glioma
    307068151 (GRB2)
   05221 Acute myeloid leukemia
    307068151 (GRB2)
   05220 Chronic myeloid leukemia
    307068151 (GRB2)
   05211 Renal cell carcinoma
    307068151 (GRB2)
   05215 Prostate cancer
    307068151 (GRB2)
   05213 Endometrial cancer
    307068151 (GRB2)
   05224 Breast cancer
    307068151 (GRB2)
   05223 Non-small cell lung cancer
    307068151 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    307068151 (GRB2)
   05160 Hepatitis C
    307068151 (GRB2)
   05163 Human cytomegalovirus infection
    307068151 (GRB2)
   05165 Human papillomavirus infection
    307068151 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    307068151 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    307068151 (GRB2)
   01522 Endocrine resistance
    307068151 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hamp04131]
    307068151 (GRB2)
Membrane trafficking [BR:hamp04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    307068151 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 SH2_2 DUF5093 DUF7145 hSH3 SH3_4
Other DBs
NCBI-GeneID: 307068151
NCBI-ProteinID: XP_079581956
LinkDB
Position
19:19058488..19120909
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagccaccgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagag
ctcaatgggaaagacggcttcatccccaagaattacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcacgat
ggggcctttcttatccgagagagcgagagtgctcctggggatttctccctctctgtcaag
tttggaaatgatgtacagcacttcaaggtgctccgagacggggctggaaagtatttcctc
tgggtggtcaagttcaattctttgaacgagctggtagattatcacagatctacatccgtc
tccagaaaccagcagatatttctccgggacatagagcaggtgccacagcaaccgacgtac
gtccaagccctctttgactttgatccccaagaggatggagagctgggattccgtcgggga
gactttatccacgtcatggataactcagaccccaactggtggaagggggcttgccacggg
cagaccggcatgtttccacgcaattacgtcacccccgtgaaccggaacgtctaa

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