Halomonas sp. M1: P8S55_02040
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Entry
P8S55_02040 CDS
T10932
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
hamz Halomonas sp. M1
Pathway
hamz00270
Cysteine and methionine metabolism
hamz00450
Selenocompound metabolism
hamz00670
One carbon pool by folate
hamz01100
Metabolic pathways
hamz01110
Biosynthesis of secondary metabolites
hamz01230
Biosynthesis of amino acids
hamz04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
hamz00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
P8S55_02040 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
P8S55_02040 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
P8S55_02040 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
P8S55_02040 (metH)
04980 Cobalamin transport and metabolism
P8S55_02040 (metH)
Enzymes [BR:
hamz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
P8S55_02040 (metH)
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Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
WFE71880
UniProt:
A0AAX3SBX9
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Position
complement(456808..460503)
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AA seq
1231 aa
AA seq
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MAASDLTASLTQRLTQRILILDGGMGTMLQNAELSEEDFRGDRFSDWPSDLKGNNDLLAL
TCPDVVARIHRDYLEAGADILETNTFNSTRLSQADYDMEELVPELNRESARLAREVCDAV
AAETDIPRYVAGVLGPTSRTASLSPDVNDPAKRNVTFDELRENYYEAASCLIEGGADLIM
IETIFDTLNAKAAIYALEELFDDLGRRLPVMISGTITDASGRTLSGQTTEAFWNSVRHAQ
PLSVGLNCALGAEELRPYIEELSTKANTFVSAHPNAGLPNEFGEYDQTPEEMAAIVSEFA
ASGLVNIIGGCCGSTPEHIRAIADAVRPMTPRQVPKRDHACRLSGLEPFNIQADSLFVNV
GERTNVTGSARFKRLIVEEDFTTALEVALEQVENGAQIIDINMDEGMLESQEAMVRFLNL
IAGEPDIARVPIMIDSSKWDIIEAGLKCVQGKAVVNSISLKEGEAAFREQATKCRRFGAA
IVVMAFDEEGQADTFARKTEICERAYRLLVDDIGFPAEDIIFDPNIFAIATGIDEHNNYA
VDFIEATQWIRDNLPHAMISGGVSNVSFSFRGNNPVREAIHSVFLYHAIRAGLSMGIVNA
GQLAVYDDLPAELRDAVEDVVLNRRSDGTERLLELADKYKGDGSGAAKKEDLEWRSWPVN
KRIEHALVKGVTAFIEEDTEQARAEAARPIEVIEGPLMDGMNVVGDLFGAGKMFLPQVVK
SARVMKQAVAYLIPYIEAEKSEETQAKGKIVMATVKGDVHDIGKNIVGVVLQCNNYEVID
LGVMVPTEKILQAAIDHNADIIGLSGLITPSLDEMVHVAKEMQRRGMSLPLLIGGATTSK
AHTAVKIEPQYEHPVIYVTDASRAVGVAGKLLAPNLKPAYVAEIREEYEKVRERNAKRRP
KAADLDYTQARKRRFRTDWNTLTPAKPNTLGLITFDDYDLEELVERIDWTPFFMSWQLAG
KYPKILEDDIVGEAARNLFADAKVMLRKLIDEKRVQARGVIGLWPANSVDDDVIEVYADE
SRTEVVEHLHHIRQQTTKGRDGICYSLADFIAPKESGKADWIGGFAVTTGHGVDELSKAY
EAAGDDYNAILVQALTDRLAEAFAERMHERVRKEFWGYVPEETLDNDALIAEKYQGIRPA
PGYPACPDHTEKATLFRLLNAPENTGLTLTENFAMWPAAAVSGWYFAHPQSKYFSTGKIT
RDQVEAIAERKQMPLAEMERWLSPVLSYDPS
NT seq
3696 nt
NT seq
+upstream
nt +downstream
nt
atggctgctagtgatttgactgcctccctcacccaacgccttacccaacgcatcctgatt
cttgatggcggtatgggcaccatgctgcagaatgctgaactcagcgaggaggattttcgc
ggtgaccggttcagtgactggccgtctgacctaaaaggtaacaatgacttattagcgctt
acctgccccgatgtcgttgcacgtattcatcgcgactatttggaagcgggcgctgatatt
cttgaaactaatacgtttaacagcacccggttgtctcaggccgattatgacatggaagag
ctggtaccagaactcaaccgtgagtcggcacgtttggctcgggaagtatgcgatgcagta
gccgccgaaactgacatcccgcgctacgtcgcgggcgtgcttggcccaacatcgcgcact
gcctccctctcaccggatgtaaacgatcccgctaaacgtaatgtcacctttgatgagctg
cgtgaaaactactatgaagcggccagctgtttaattgagggtggcgccgatctcatcatg
atcgaaaccatcttcgatacgctcaacgccaaagcggccatctatgcgcttgaagagctc
ttcgatgatttaggacggcgcctgccggtgatgatttctggcactattaccgacgcttcc
ggccgcacgctttctggccaaacgaccgaagcgttctggaactccgttcgccatgcccag
ccgctttccgtggggttgaactgtgccctcggcgccgaagagctgcgtccttacattgaa
gagctttctactaaagctaatacctttgtttctgcccaccccaacgctggcctgcctaat
gagtttggtgaatatgaccaaacgccggaagagatggccgcgatagtcagcgagttcgcc
gcgagcgggctggttaacatcatcggtggttgctgtgggtcaacgcctgaacatatccgt
gctattgctgacgccgtgcgccccatgacgccacgccaagtgcccaagcgtgatcacgct
tgccgcctatcggggctagagccttttaacatccaagcggattcgctgtttgtaaacgtg
ggtgagcggaccaacgtcactggctccgcacgctttaaacgcttgatcgtcgaggaagat
ttcactactgccttagaggtagcgcttgagcaggtggagaacggcgcacagatcatcgac
atcaacatggatgagggcatgcttgagtcccaggaagccatggtgcgctttctgaactta
attgccggtgagcctgatattgctcgtgtgccgattatgatcgactcctctaaatgggac
atcatcgaagcgggcctaaagtgcgttcaaggtaaggcggttgtgaactcgatctcactg
aaagagggcgaagccgcattccgcgaacaagccaccaagtgccgccgcttcggtgcagcg
attgtcgtcatggcgtttgacgaagagggccaagcggatacctttgcccgcaaaactgag
atctgtgaacgcgcctaccgcctgctagttgatgacattggcttccctgcagaagacatc
attttcgatcccaatattttcgccatcgccaccggcattgacgagcacaataactacgca
gtcgattttattgaggcgacacagtggatacgtgacaacctgccccatgcgatgatttcc
ggtggtgtgtctaacgtctcgttctctttccggggcaataacccggtacgtgaagccatc
cactcggtatttctataccacgctattcgcgctggccttagcatggggattgtcaacgca
gggcagcttgcggtctatgatgacttgcccgctgagcttcgcgatgctgtagaagatgtg
gtactcaaccgtcgaagcgacggcaccgagcgattgcttgagcttgccgataagtacaag
ggcgacggcagcggcgctgccaaaaaggaggacctggagtggcgcagctggccagtcaac
aagcgcattgaacatgcactggtaaaaggtgttaccgcgtttattgaagaagataccgag
caagcccgtgccgaagcggcccgccccatcgaggtcattgaaggcccattaatggatggc
atgaacgtggtgggcgacctctttggcgcgggcaaaatgttcttgcctcaggtggttaag
tcagcgcgggttatgaagcaggccgttgcctacttgattccttatatcgaagccgagaaa
agtgaagagacccaggccaagggtaaaattgttatggccacggtcaaaggggatgttcat
gacatcggcaaaaatatcgttggtgtggtgttgcagtgtaataactatgaagttatcgat
ctgggtgtgatggtacccactgaaaaaatcctgcaagccgctattgatcacaatgccgat
atcattggcctttccggcttaatcacgccctcgcttgatgaaatggtgcacgttgccaaa
gaaatgcagcgccgcgggatgagcctgccgctattaattggcggggcgaccacctccaaa
gcgcatacggcggttaaaattgagccacaatatgagcatccagtgatctacgtcaccgat
gcctcccgcgcagtgggcgttgctggcaagctgctagcacctaatttaaagcccgcctac
gtggcagagattcgtgaagagtatgaaaaagtgcgcgagcgtaacgccaaacgtcgcccg
aaagcggcggacttggactacacccaagcgcgtaagcgacgctttcgcaccgattggaac
accctcacgccggctaaacctaatacccttggtttaatcacctttgatgactacgatcta
gaagaactggtagagcggatcgattggacaccgttctttatgagctggcagctcgccggg
aagtaccccaaaattctcgaagatgacattgtcggcgaagcggcgcgtaacctctttgcc
gacgcaaaggttatgttgcgtaaacttatcgacgaaaagcgcgttcaagcccgaggggtt
atcggcttgtggccagcaaatagcgtagatgatgatgtcatcgaagtgtacgccgatgaa
agccgcaccgaggtggtggaacacttgcatcatattcgtcaacaaactaccaaaggccgc
gacggcatttgttatagccttgcagactttatcgcacccaaagagagcggcaaagccgac
tggattggtggcttcgccgtcacaactggccacggtgtggatgagctttccaaagcctac
gaagcggcgggtgacgactataacgccattttagtccaggcactgaccgaccggctggct
gaagcctttgctgaacgcatgcacgagcgggtgcgtaaagagttttggggctacgtgccg
gaagaaacgctagataacgatgcgctgattgccgagaagtatcagggtatccgccctgct
ccaggctaccctgcctgcccggatcataccgaaaaagccacgctcttccgcctgcttaat
gcgccggaaaacactgggcttacgctcacggaaaacttcgctatgtggcctgccgcagcg
gtttccggctggtatttcgcccacccgcagtcaaagtacttctctaccggaaaaatcacc
cgcgaccaagttgaggctatcgccgaacgtaaacagatgccgttagcagagatggagcgc
tggctatcccctgtactctcttacgaccctagctaa
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