KEGG   Herminiimonas arsenicoxydans: HEAR0124
Entry
HEAR0124          CDS       T00490                                 
Symbol
metH
Name
(GenBank) Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase) (Methionine synthase, vitamin-B12 dependent) (MS)
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
har  Herminiimonas arsenicoxydans
Pathway
har00270  Cysteine and methionine metabolism
har00450  Selenocompound metabolism
har00670  One carbon pool by folate
har01100  Metabolic pathways
har01110  Biosynthesis of secondary metabolites
har01230  Biosynthesis of amino acids
har04980  Cobalamin transport and metabolism
har04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:har00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    HEAR0124 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    HEAR0124 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    HEAR0124 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    HEAR0124 (metH)
   04980 Cobalamin transport and metabolism
    HEAR0124 (metH)
Enzymes [BR:har01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     HEAR0124 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: CAL60360
UniProt: A4G1H3
LinkDB
Position
118780..122538
AA seq 1252 aa
MKRDAISPTETLLRDLMARRILILDGAMGTMIQQYKLTEEDYRGTRFADFAVPGKEVFVK
GNNELLSLTQPHVISEIHEKYLAAGADLIESNTFGATTVAQDDYHMGHLAYEMNVASARL
ARAACDKYSTPDKPRFVAGALGPTPKTASISPDVNDPAARNVTFDQLVASYLEQTRGLVE
GGADVLLVETIFDTLNCKAALFAIDQFFEESGQRLPIMISGTVTDASGRILSGQTVPAFW
HSIRHARPLTVGLNCALGAALMRPYAEELSKIADTFVCIYPNAGLPNPMSDTGFDETPDV
TSSLLKDFAESGFVNIAGGCCGTTPDHIKAIADTVANIAPRIVPTIEPTMKLSGLEPFII
DDNSLFVNVGERTNVTGSKAFARLIINEKYDEALTVARQQVENGAQIIDINMDEAMLDSE
AAMTRFLNSVASEPDIARVPIMIDSSKWSVIEAGLKCVQGKAIVNSISMKEGEEKFLHDA
KLCRRYGAAVIVMAFDEKGQADTFERKIEICERAYWLLVNEVDFPPEDIIFDPNIFAIAT
GIEEHNNYAVDFINSVRWIKENLPHAKISGGVSNVSFSFRGNDPAREAIHTVFLYHAIKA
GMTMGIVNAGMVGVYDNLPAELKECVEDVVLNRREDATERMIEIAATLKAGDKKEEATLE
WRSGTVQQRLAHALVQGITQWIVEDTEEARQELLKNGGRPIHVIEGPLMDGMNIVGDLFG
QGKMFLPQVVKSARVMKQAVAHLIPFIEEEKRLLQEQTGIVSKPKGKIVIATVKGDVHDI
GKNIVSVVLQCNNFEVVNMGVMVPCSEILARAKAENADIIGLSGLITPSLEEMAYVAKEM
QRDEYFRGLKTPLLIGGATTSRAHTAVKIAHNYDGPVVYVPDASRSVSVAQSLLTPESRD
QYIADIATDYERIRVQHANKKTLPMLSLEQARANKMQVEFTGKYAPVKPKFIGRRVFKNV
DLATIAQYIDWGPFFQTWDLAGPYPAILTDEVVGDAATKVFAEGQALLKKIIEGRWLTAN
GVIALLPANTVNDDDIEVYTDETRTQVAFTYYGVRQQTVKPIIDGVQRPNQCLADFIAPK
SSGIADYIGLFAVTAGLGIEKYEKRFEDAYDDYSSIMLKSLADRLAEAFAEQLHERVRTD
LWGYVPDEALSNEAMIKEEYLGIRPAPGYPACPEHTVKAEMFKTLQAEEIGMMLTDSFAM
FPGAAVSGFYFAHPEAKYFVVGKIGEDQVKDMVLRRGVSQEDIERWLAPNLS
NT seq 3759 nt   +upstreamnt  +downstreamnt
atgaaacgcgacgctatttctccgaccgaaaccctcttgcgcgacctgatggcgcgccgc
atcctgattctggatggcgcgatggggacgatgattcagcaatacaagctgacagaagaa
gattatcgcggcacgcgtttcgccgacttcgcggtgcccggcaaggaagttttcgtcaag
ggcaataacgaattattgtcgctgacccagccgcatgtgatcagcgaaattcacgaaaag
tatctggcggccggtgccgatctgatcgaaagcaatacctttggcgctactacggtagcg
caggacgattaccacatgggtcatctggcctatgaaatgaacgtggcctcggcgcgcctg
gcgcgcgctgcctgcgacaagtattcgacgccggacaagccgcgcttcgtggccggcgca
ctcggccccacgccgaagaccgcctcgatctcgccggacgtcaacgatccggcggcacgc
aatgtgaccttcgatcagttggtcgcttcgtatctggaacagacgcgcggcctggtggaa
ggcggcgccgacgtgctgctggtcgaaaccattttcgatacgctcaactgcaaagccgca
ttattcgcaatcgatcaattttttgaagagtcgggccagcgtttgcccatcatgatctct
ggcactgtgaccgatgcctcgggccgcattctgtccggccaaacggtgccggcattctgg
cattcgattcgccatgccagaccgctgacggtgggcttgaactgcgcactcggtgcggcg
ctgatgcgtccgtatgcggaagaattgtcgaagatcgccgataccttcgtctgtatttat
ccgaatgccggcttgcccaatccgatgagtgacaccggtttcgacgagacgccggatgtg
acctcctccttgctgaaggattttgccgaaagcggcttcgtcaatatcgccggcggttgc
tgcggcaccacgccggatcacatcaaggcgatcgccgatacggtcgcgaatattgcaccg
cgcatcgtccccacgatagaaccaacgatgaaactgtcgggcctggaacccttcatcatc
gatgacaactctctgtttgttaacgtcggcgaacgtaccaacgtcaccggctccaaagca
tttgcgcgcctgatcatcaatgaaaaatacgatgaagcgctgaccgttgcacggcaacag
gtagaaaacggcgcgcagatcatcgacatcaatatggatgaggcgatgctcgattcagag
gcggcgatgacgcgcttcctgaattcggtggcatccgagccggacatcgcacgcgtgcct
atcatgatcgattcgtcgaaatggtcggtcattgaagccggtttgaaatgcgtgcagggc
aaggcgatcgtcaactcgatttcgatgaaggaaggcgaggaaaaattcctgcatgacgcg
aagttgtgccgtcgttatggcgcggccgtgatcgtgatggccttcgatgaaaaaggtcag
gccgatactttcgaacgcaagatagaaatttgcgagcgcgcgtattggctgctggtcaat
gaagtcgatttcccgccggaagacatcattttcgatccgaacattttcgcgattgcgacc
ggtatcgaagaacacaataactacgccgtcgactttatcaattcggtgcgctggatcaag
gagaatttgccgcacgcaaaaatcagcggcggcgtatccaacgtcagcttctcgttccgc
ggcaacgatccggcgcgcgaagcgatccataccgtgttcctgtatcacgccatcaaggcc
ggcatgacgatgggtatcgtcaacgccggcatggtcggcgtgtacgacaatctgccggca
gagttgaaagaatgcgtcgaagacgtggtgctgaatcgtcgtgaagacgccaccgagcgc
atgatcgaaattgccgccaccctgaaagccggcgacaagaaggaagaagccacgctggaa
tggcgcagcggtaccgtgcagcagcgtctggcgcatgcgctggtacagggcatcacgcaa
tggatcgttgaagacaccgaagaagcgcgacaggaattgctgaaaaatggcggtcgtccc
atccatgtgatcgaaggtccgctgatggatggcatgaacatcgtcggcgatctgttcggc
cagggcaaaatgtttttgccgcaggtggtcaaatctgcgcgcgtgatgaagcaggcggtt
gcgcatctgatcccgttcatcgaggaagaaaaacgtctgttgcaggaacaaaccggtatc
gtcagcaaaccgaagggcaagatcgtcatcgctaccgtaaagggtgatgtgcatgacatc
ggcaagaacatcgtatcggtggtcctgcaatgcaataacttcgaagtcgtcaacatgggc
gtgatggtgccatgttcggaaattctcgcgcgcgccaaagccgagaatgccgacatcatc
ggcctctccggattgatcacgccgtcgctggaagaaatggcttacgtcgcgaaggaaatg
cagcgcgacgaatacttccgtggcttgaaaacgccactgctgatcggcggtgcgaccacc
agccgtgcgcataccgccgtcaagatcgcgcacaactacgatggtccggtcgtgtatgta
ccggatgcctcgcgttcggtatcggttgcgcaatccctgctgacgccggaaagtcgcgat
caatacattgccgatatcgcgaccgattacgagcgcatacgcgtacagcatgcgaacaag
aagaccttgccgatgctgagcctggagcaggcgcgcgccaacaagatgcaggtggaattc
accggcaaatatgcgccggtcaaaccgaagttcatcggccgtcgcgtgttcaagaatgtc
gatctggcgacgattgcgcaatatatcgattggggcccgttcttccagacctgggatctg
gccggcccctaccctgcgattctgacggatgaagtggtgggcgatgccgcgaccaaggtg
tttgccgaagggcaggccttgctgaaaaaaatcattgaaggtcgctggctgaccgccaac
ggcgtgattgcattgctgccggccaataccgtcaatgacgacgacatcgaggtgtacacc
gatgaaacgcgcactcaggttgctttcacctattacggtgtgcgccagcaaaccgtcaag
ccgatcatcgatggcgtgcagcgtcccaatcagtgtctggccgatttcattgcaccgaaa
tcatccggcattgccgattacatcggcctgtttgcagtgacggcagggctgggtattgaa
aaatacgagaagcgctttgaagatgcgtacgacgattattcttccatcatgctgaagtcg
ctggcggatcgtctggcggaagcgttcgccgaacagctgcatgaacgcgtgcgtaccgat
ttgtggggttatgtgccggatgaagccttgagcaatgaagcaatgatcaaggaagaatac
ctgggcatacgccctgctcccggctatccggcgtgccccgaacatacggtcaaggctgag
atgttcaagaccttgcaggcggaagaaatcggcatgatgctgaccgattcgtttgcgatg
ttcccgggtgcggcggtatctggtttttatttcgcccatccggaagcaaaatactttgtg
gtcggcaaaatcggcgaggatcaggtcaaggacatggtgctgcgacgcggcgtttcgcag
gaagatatcgaacgctggctggcgcctaacctgtcttga

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