Hemicordylus capensis (graceful crag lizard): 128345684
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Entry
128345684 CDS
T08891
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1-like isoform X1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
hcg
Hemicordylus capensis (graceful crag lizard)
Pathway
hcg00140
Steroid hormone biosynthesis
hcg01100
Metabolic pathways
Module
hcg_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
hcg_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
hcg_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
hcg_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
hcg00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
128345684
Enzymes [BR:
hcg01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
128345684
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
128345684
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
Polysacc_synt_2
NAD_binding_4
NAD_binding_10
RmlD_sub_bind
NmrA
NAD_binding_7
KR
Motif
Other DBs
NCBI-GeneID:
128345684
NCBI-ProteinID:
XP_053153978
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Position
2:162138086..162157349
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AA seq
440 aa
AA seq
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MGVVGGSWATLILKDLHSCKAVAAETETLSIPNTWLPPPPLSLPCCKKQGLPVQAAPEHN
CTAMSLAGLKCLVTGAGGFLGRRIVCQLLEEEEGLAEVRVLDKTISSELLQNFAKRKNKT
LLTVMQGDIRDGKFLHTAVKGVSLVIHTACIIDPLGLVEQQTLWDVNVRGTQLLLETCIF
YDVPHFIYTSSLEVAGPNCRGDPIYDGDEDTVYQSTTGFLYAETKRAAEKYVLDLDGLQL
KNGTSLVTCALRSMYIFGEGSTFLLQHLDECILNNNVFLRNSRKEAFVNPVYVGNIAWAH
IQLAKAMRDPEKVERIRGQFYYISDDTPHVSYADFNYELAKELGFGIEPKLPMPLMMFYC
YALLLEIVSFLLWPFVRYIPVINRQLLTLLNTPFTFSYKKARRDFGYRPRYTWEEAKQQT
SQWIAEVAPLRAAYLKNKTL
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgggagtggtgggggggagctgggcaaccttgattctgaaggatttgcacagttgcaaa
gctgtggctgctgagactgagactctgagcatccctaacacatggttgccccccccccct
ctctctctcccttgctgtaagaaacaggggctgcccgtgcaagctgctcctgagcacaac
tgcacagctatgtctctggcaggactgaagtgtctggtaacaggagctggtgggttcctt
ggtcgaaggattgtttgccagttgctggaagaagaagagggcctggccgaggtccgagtc
ctggacaaaacaatcagttctgagttgctccagaattttgcaaaacgaaagaataaaact
ctcttgacagtgatgcaaggggatatccgggatgggaaatttcttcacacagctgtcaag
ggtgtctcgcttgtcatccacacggcttgcatcattgaccccttgggactggtagagcag
cagacactctgggatgtcaatgtcagaggtacgcagctgctgctggagacctgcattttc
tacgacgtcccacactttatctataccagcagccttgaagtggctggtccaaactgcaga
ggtgaccccatctatgatggcgatgaagacacagtgtaccagagcaccacaggattcctt
tatgctgaaacgaagagagcagcagagaaatatgtgctggacttggatggcctgcaactg
aagaacggcaccagcctagtgacatgtgctctgaggtccatgtatatttttggagaagga
agtactttccttctgcaacatcttgatgagtgcatcttaaacaataatgtctttctgagg
aactccaggaaggaggcttttgtaaatccagtctatgtggggaatattgcttgggctcat
atccagttggctaaagccatgagggatccagaaaaggtcgagcggatcagaggacaattc
tattatatctcagatgatactccccatgtcagctatgcagacttcaattacgagttggct
aaagagctggggtttggcatcgaacccaagctaccaatgcctctaatgatgttttactgt
tatgccctgttgctggagattgtgagcttcctgctctggccctttgtcaggtacatccct
gtcatcaatcgtcagcttctgactttgcttaatactccgtttaccttttcttacaagaag
gcacgcagggattttggctacaggcctcgctacacgtgggaagaagccaagcagcagacc
agccagtggattgccgaggtagcaccactgagggcagcctacctgaaaaacaagactctc
taa
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