KEGG   Halomonas chromatireducens: LOKO_01911
Entry
LOKO_01911        CDS       T04292                                 
Symbol
metH
Name
(GenBank) Methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
hco  Halomonas chromatireducens
Pathway
hco00270  Cysteine and methionine metabolism
hco00450  Selenocompound metabolism
hco00670  One carbon pool by folate
hco01100  Metabolic pathways
hco01110  Biosynthesis of secondary metabolites
hco01230  Biosynthesis of amino acids
hco04980  Cobalamin transport and metabolism
hco04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:hco00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    LOKO_01911 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    LOKO_01911 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    LOKO_01911 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    LOKO_01911 (metH)
   04980 Cobalamin transport and metabolism
    LOKO_01911 (metH)
Enzymes [BR:hco01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     LOKO_01911 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding MtrH Radical_SAM
Other DBs
NCBI-ProteinID: AMD00979
UniProt: A0A125R045
LinkDB
Position
2022754..2026455
AA seq 1233 aa
MAAVPSALTTTLTEQLGQRILMLDGGMGTMLQNAELDEADFRGDRFHDWPSDLKGNNDLL
ALTCPDLVTRIHRQYLEAGADIIETNTFNSTRLSQSDYGMEELVPELNRESARLAREVCD
AVASETGVPRYVAGVLGPTSRTASLSPDVNDPAKRNVTFDALRENYYQAAEALIEGGADL
IMIETIFDTLNAKAAIFALEELFADRGERLPVMISGTITDASGRTLSGQTTEAFWNSVRH
AEPLSIGLNCALGAAELRPYLEELSTKADTFVSAHPNAGLPNEFGEYDQTPEEMAAIVAE
FAESGLVNIIGGCCGSTPEHIAAIHAAIEGMAPRQVPERPRACRLSGLEPFNIEKDSLFV
NVGERTNVTGSARFKRLIVDEDYNTALEVALEQVENGAQVIDINMDEGMLESEEAMVRFL
NLIAGEPDIARVPIMIDSSKWEIIEAGLKCVQGKAVVNSISMKEGEDAFREQATLCRRYG
AAVVVMAFDEQGQADTFARKTEICQRAYEILVDEVGFPPEDIIFDPNIFAIATGIEEHNN
YAVDFIEATRWIREHLPHAMVSGGVSNVSFSFRGNNPVREAIHSAFLYHAIRAGLSMGIV
NAGQLAVYDDLPAELRDAVEDVVLNRRPDGTERLLDIADRYKGDGSGPAKKEDLEWRSWE
VEKRISHALVKGITVYIEEDTEEARQRASRPIEVIEGPLMDGMNVVGDLFGAGKMFLPQV
VKSARVMKQAVAYLIPYIEAEKTEDTKAKGKIVMATVKGDVHDIGKNIVGVVLQCNNYDV
VDLGVMVSAEKILQTARAENADIIGLSGLITPSLDEMVHVAKEMQRQGFDLPLLIGGATT
SKAHTAVKIEPGYEHPVIYVADASRAVGVAGKLLSPALKPSYVAEIRAEYDQVRERNARR
RPKASDLSYAEARERKLPIDWASYTPPRPAVTGLKVFDSYDIEELIKRIDWTPFFMSWEL
AGKYPKILDDKVVGEAARSLFADAQEMLRKLIDEKHIQARGVIGLWPANSVDDDVIEVYA
DESRTQVVERLHHIRQQTTKNRDGVCYSLADFVAPKASGKPDWIGGFAVTTGHGVEALAE
RYKAAGDDYSAIMVQALTDRMAEAFAERMHERVRKEFWGYVPDERLDNVELIAEKYQGIR
PAPGYPACPDHTEKSTLFRLLDASANAGIDLTENFAMWPAAAVSGWYFSHPQSKYFSTGK
ITRDQVEALAERKQMSLEELERWLSPVLSYDPA
NT seq 3702 nt   +upstreamnt  +downstreamnt
atggccgccgttccctctgccttgaccaccaccctcaccgaacaactcggtcagcgtatc
ctgatgctcgatggtggcatgggtaccatgctgcagaatgctgaactcgatgaggccgac
ttccgcggtgaccgtttccacgactggccctcggacctgaagggcaataacgacctgctg
gccctgacctgccccgacctggtaacgcggattcatcgccagtacctggaggcaggcgcc
gacatcatcgaaaccaacaccttcaacagcacacgcctctcccagtccgactatggcatg
gaggaactggtccccgagctcaaccgggagtcggcgcggttggcccgtgaggtatgcgac
gccgtggccagcgaaaccggcgtgccacgctacgtggcaggcgtgctggggccaacctcc
cgcaccgcctcgctgtcgccggacgtcaatgacccggccaagcgcaacgtcaccttcgac
gcgctgcgtgaaaattactatcaagcggccgaagcgctgatcgaaggcggcgccgatctg
atcatgatcgaaaccatcttcgacaccctcaatgccaaggcggcgatcttcgctctggag
gaactgtttgccgatcgcggcgagcgcctgccggtcatgatctcgggcaccatcaccgat
gcctcggggcgcaccctttccggccagaccaccgaggcattctggaattcggtgcgacat
gccgagccgctctccatcgggctgaactgcgccctgggtgccgcagagcttcgcccctat
ctggaagaactctccaccaaggccgataccttcgtctccgcgcaccccaacgccggcctg
cccaacgagttcggtgaatacgaccagacgcccgaggagatggccgccatcgtcgccgag
ttcgccgaaagcggcctggtcaatatcatcggtggctgctgtggctccacgccggagcac
attgccgccatccacgccgcgatcgagggcatggccccgcggcaggtgcccgagcgccct
cgagcgtgccgcctgtccggcctcgagcccttcaacatcgagaaggattcactgttcgtc
aacgtcggcgagcgtaccaatgtcaccggctcggcccgcttcaagcgcctgatcgtcgac
gaggactacaacaccgccctggaggtggcactggagcaggtggagaacggtgcccaggtc
atcgacatcaacatggacgagggcatgctggagtccgaggaagccatggtgcgctttctc
aacctgatcgccggggagcccgacatcgcccgggtgccgatcatgatcgattcctcaaag
tgggagatcatcgaggccggtctcaaatgcgtccagggcaaggcggtggtcaattccatc
tccatgaaggagggtgaggacgcctttcgggagcaggctaccctgtgtcggcgctacggt
gccgccgttgtggtcatggccttcgacgagcagggccaggcagataccttcgcccgcaag
acggagatctgtcagcgggcctacgagatcctggtcgacgaggtggggttcccgccggaa
gacatcatcttcgatcccaacattttcgccatcgccaccggcatcgaagagcacaacaac
tatgcggtcgatttcatcgaggccacccgctggatacgcgagcacctgcctcacgccatg
gtctcgggcggcgtctccaacgtctcgttctcgtttcgcggcaacaatccggtgcgcgag
gcgatccattcggccttcctctatcacgccattcgcgccggcctgagcatgggcatcgtc
aatgccggccagttggccgtgtatgacgatctgccggccgaactgcgcgacgcggtggag
gacgtggtcctgaaccggcgccccgacggcaccgaacgactgctggatatcgccgatcgc
tacaagggcgatggcagcggccccgccaagaaggaggatctggagtggcgcagctgggag
gtcgagaaacgcatctcccacgccctggtcaaggggatcaccgtctatatcgaggaggac
acagaggaggcgcgccagcgggccagccgccccatcgaggtgatcgaagggccgctgatg
gatggcatgaacgtggttggcgacctgttcggggccggcaagatgttcctgccccaggtg
gtcaagtcagcacgggtcatgaagcaggcggtggcctatctgatcccctatatcgaagcg
gagaagaccgaggataccaaggccaagggcaagatcgtcatggccacggtgaagggcgac
gtccacgatatcggcaagaacatcgtcggcgtggtcctgcagtgcaacaactacgatgtg
gtcgatctcggcgtcatggtgtcggcggagaagatcctgcagacggccagggccgagaat
gccgacatcatcggcctgtcgggcctgatcaccccttccctcgacgagatggtgcatgtg
gccaaggagatgcagcgacagggcttcgacctgccgctgctgatcggtggagccaccacc
tccaaggcgcataccgcggtgaagatcgagcccggctacgagcacccggtgatctacgtg
gcggatgcctcccgcgccgtgggcgtggccggcaagctgctgtcgccggcgctgaagccg
agctatgtggccgagattcgcgcagagtatgatcaggtgcgcgaacgcaatgcccggcgc
cgccccaaggcgtccgacctgagctatgctgaggcccgcgaacgcaagttgcccatcgac
tgggccagctacaccccgccgcgccccgccgtcaccgggctgaaggtattcgacagctac
gatatcgaggagctgatcaagcgcatcgactggacccccttcttcatgagctgggagctg
gcgggcaagtatccgaagatcctcgatgacaaggtggtcggcgaagccgcccgcagcctc
ttcgccgatgcccaggagatgctgcgcaagctgatcgacgagaagcacatccaggcgcgc
ggcgtgatcgggctgtggccggccaacagcgtcgacgatgatgtcatcgaggtctacgcc
gacgagtcgcgtacccaggtggtcgagcggctgcaccacatccgccagcagaccaccaag
aaccgcgacggggtctgctacagcctcgccgacttcgtggcgcccaaggcgtcgggcaag
ccggactggatcggcggtttcgccgtgaccaccgggcatggtgtcgaggcactggccgag
cgctacaaggccgccggcgacgactacagcgcaatcatggtgcaggccttgaccgaccgc
atggccgaggccttcgccgaacgcatgcacgagcgggtgcgcaaggaattctggggctat
gtgccggacgaacgcctggacaacgtcgagctgatcgccgagaagtaccagggcatccgg
cccgcgccggggtatcccgcctgccccgaccacaccgagaagagcaccctgttccgtctg
ctcgatgcctccgcgaatgccggcatcgatctcaccgagaacttcgccatgtggccggcg
gcagcggtttccggctggtatttctcgcacccgcagtcgaagtacttctccaccggcaag
atcacccgggaccaggtggaagccctggctgagcgcaagcagatgagcctggaggagctg
gagcgctggctgtcgccagtgctctcctacgaccccgcatga

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