Halarcobacter ebronensis: AEBR_0268
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Entry
AEBR_0268 CDS
T06616
Symbol
metH
Name
(GenBank) cobalamin-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
hebr
Halarcobacter ebronensis
Pathway
hebr00270
Cysteine and methionine metabolism
hebr00450
Selenocompound metabolism
hebr00670
One carbon pool by folate
hebr01100
Metabolic pathways
hebr01110
Biosynthesis of secondary metabolites
hebr01230
Biosynthesis of amino acids
hebr04981
Folate transport and metabolism
Module
hebr_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
hebr00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
AEBR_0268 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
AEBR_0268 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
AEBR_0268 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
AEBR_0268 (metH)
04980 Cobalamin transport and metabolism
AEBR_0268 (metH)
Enzymes [BR:
hebr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
AEBR_0268 (metH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
CdhD
Motif
Other DBs
NCBI-ProteinID:
QKF80784
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Position
251428..254898
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AA seq
1156 aa
AA seq
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MIEKIKEIIENRVLIIDGAMGTQLQIADIKNESWQYEGKDLEGCNELLNLTAPNILEGIH
DAYAIAGADLITTNTFGSMPWVLEEYGIAKTSYELSKLGAQLVKKSCEKFSTKEKPRFVL
GSIGPGTKLPSLGHITYDEMFEGYKIMAQGLVDGGCDIFLLETCQDPLQIKAALHALKEV
SPQTPIMVSVTIELSGTMLIGTDAMTIAAIMAPFNILSLGFNCGTGPKQVHKHVKALSEV
CRFPISVHSNAGLPQNRGGVTYYPMQPKEFTELSIEFLEFNGVSFLGGCCGTTPAHIEAL
AKEASKIKPKKPSGFLKASLASLFNVVPLKQDPAPLLIGERSNATGSKAFRELLKANDYE
GTLSVGQQQVRAGAHVIDVSVGFAGRDEREDMNKVVSLYSQKVALPLMPDSTQLPALEEA
LKQIGGRPIINSVNLEDGEEKFDAVCNLAKKFGAALVCLVIDEVGMAKTKNRKLEVAERI
YDLCVNRHGFNPDDLVFDMLTFTIGSGDDEYRTAGMETLEAIREFQLRHPEVGTTLGLSN
ISFGLSINARIYLNSIYLDHCVKAGLTSAIVNVKHILPLNKISDEDRKACDNLIFNNHEN
GDPLFAFIDHFSNVESQEDKSDEEYEKLESIDKVKKLLLDGDKERMLPLVEELRHSVNPE
IIVNEWLIDGMKVIGELFGSGQMQLPFVLQSAETMKATVDALNPYLPKEEKASETVLVLG
TVKGDVHDVGKNLVDIILSNNGFKVINIGIKADLNDFIIAVKEHKAQAIGMSGLLVKSTA
VMKDNLEELQKQGIDIPVLLGGAALTKSFVNDYCRPIYDGPIFYCRDAFDGVVSMQRIES
GELDNTTLAADLIDEDAIAKNEEQEIIVKESDVELPEESTFTFPPLWGRVAQNKNMINKE
LSFKWINHRVLFRQRWGYKRAKQSSEEFLKHEKEVVEPLYEKLKEQFISKGLFAPIAIYA
YFPCIAKENKLYIFSEEYAFHSLEEAKKVPPLEKAIKVFEFPRQKRKPHRCIADFFANNR
LDVVAFSLASAGVKLSPYEAKLYKESKFTEYYQVHGLGVELAEALAEVIHKQVRLDLDIV
PKEGHTLNDVQMKQYVGCRYSPGYAACPELELSKDIFDLLKPEEFGITLSETFQIDPEQS
TCAIIVPHHKANYYNI
NT seq
3471 nt
NT seq
+upstream
nt +downstream
nt
atgattgaaaaaataaaagaaataatagaaaatagagtcttaattatagatggtgcaatg
ggaacccaacttcaaattgcagatattaaaaatgaatcttggcaatatgaaggtaaagat
ttagaagggtgtaatgaattattaaacttaactgcaccaaatatcttagagggaattcat
gatgcttatgctattgcaggggctgatttaatcactacaaatacttttggttctatgcct
tgggtattagaagagtatggaatagcaaaaacctcttatgagctttcaaaactgggtgca
caacttgtaaaaaaaagttgtgagaagtttagtactaaagagaaacctagatttgtttta
ggttcaattggtcctggaacaaaacttcctagtcttggacatataacttatgatgagatg
tttgaagggtataagattatggctcaaggtcttgttgatggaggatgtgacatcttctta
cttgagacttgccaagatcctcttcaaataaaagctgcacttcatgctttaaaagaggtt
tctccacaaactcctattatggtttctgtaaccattgagttaagtggaacaatgcttatt
gggacagatgcaatgacaattgcagctattatggctccttttaatattttatctttaggg
tttaactgtggaacaggaccaaaacaggtacataaacatgtaaaagctctaagtgaagtt
tgcagattcccgatatcagttcactcaaatgcaggtcttcctcaaaatagaggtggagta
acttattatccaatgcagccaaaagagtttaccgagcttagtattgagtttttagagttt
aatggagtctcttttttaggtggttgttgtggaacaacaccagcacacattgaagctttg
gcaaaagaggcttcaaagataaaaccaaaaaaaccaagtggctttttaaaagcttcattg
gcatcactgtttaatgtagttcccctaaaacaagatccagcaccgcttctaataggggag
agatctaatgcaacaggaagtaaagcctttagagaacttctaaaagcaaatgattatgag
ggaacattatctgttggtcaacaacaagtaagagcaggagcacatgtaattgatgtttct
gtcggatttgctggacgtgatgaaagagaagatatgaataaagttgtatctttatattct
caaaaagttgcacttccacttatgccagactcaacgcaacttccagctcttgaagaggct
ttaaaacagattggtggaagaccaataattaactcagttaatcttgaagatggggaagag
aaatttgatgcagtttgtaatttagccaaaaagtttggtgcagcacttgtttgtttagtt
attgatgaagttggaatggcaaaaacaaagaatagaaaacttgaagttgcagaaagaatc
tatgatttatgtgtaaatagacatggctttaatccagatgatttagtttttgatatgctt
acgtttactattggttcaggggatgatgagtatagaacagcaggaatggaaacccttgaa
gcaatcagagagtttcaactgcgtcatccagaagtgggtaccactttaggactatcaaat
atctcttttggattatcaataaatgcaagaatatatttaaactcaatctatcttgatcac
tgtgtaaaagcagggcttacaagtgctattgtaaatgtaaaacatattttgccactaaat
aaaataagtgatgaagatagaaaagcttgtgataatctaatttttaataaccatgaaaat
ggtgacccactttttgcttttattgatcacttttcaaatgtggagtcgcaagaagacaaa
agtgatgaagagtatgagaagttggagtcaatagataaggtaaaaaaacttcttttagat
ggggataaagagagaatgcttccccttgttgaagagcttagacatagtgttaaccctgag
ataatagttaatgaatggcttattgatggaatgaaagtaataggagaactttttggaagt
ggtcaaatgcaacttccttttgtacttcaaagtgctgagactatgaaagcaacagttgat
gctttaaatccatatttaccaaaagaggaaaaagcaagtgaaaccgtacttgtattagga
actgtaaaaggagatgttcatgatgttggtaaaaaccttgtggatattattctttcaaat
aatggtttcaaagtaataaatattggaataaaagctgatctaaatgactttataattgct
gtaaaagagcataaagcccaagcaattggaatgagtggattgcttgtaaaaagtaccgct
gtaatgaaagacaatcttgaagagcttcaaaaacaaggaatagatattcctgtactttta
ggaggagctgcccttacaaaaagttttgtaaatgattattgcagacctatctatgatggt
ccaattttctattgtagagatgcttttgatggtgttgtatctatgcaaagaattgaaagt
ggcgagttagataacaccactttagcagcagatttaatagatgaagatgcaatagcaaaa
aatgaagagcaagagattattgtaaaagagtctgatgttgaacttcctgaagagtctact
tttacttttcctcctctttggggaagagttgcacaaaataaaaatatgataaataaagag
cttagttttaaatggataaatcatagggttttatttagacaaagatggggatataaaaga
gcaaaacaatctagtgaagagtttttaaaacatgaaaaagaggtagttgagccgctatat
gaaaaactaaaagagcagtttatttctaaaggtttgtttgctccaatagcaatatatgca
tatttcccttgtattgcaaaagagaataagctttatatttttagtgaagagtatgctttt
cattcccttgaagaggcaaaaaaagtaccacctttggaaaaagcaataaaagtttttgag
ttcccaaggcaaaaaagaaaaccacatagatgtattgctgatttctttgcgaataataga
cttgatgtggttgccttttcacttgcaagtgcaggagtaaaattaagcccttatgaagct
aagctttataaagagagtaaatttacggaatattatcaagttcatggattaggagttgag
ctagctgaagctttggctgaggtgattcataaacaagtaagacttgatttggatattgtt
ccaaaagaaggacatacgctaaatgatgtacagatgaaacaatatgtagggtgtagatac
tctccaggatacgctgcttgtccagagttagaattaagcaaagatatttttgatttatta
aaacctgaagagtttggaataactctaagtgagactttccaaattgatccagaacagagt
acttgcgccataatagtgccacatcacaaagccaactactacaacatctag
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