KEGG   Helicobacter pylori F16: HPF16_0752
Entry
HPF16_0752        CDS       T01910                                 
Symbol
hefC
Name
(GenBank) cytoplasmic pump protein of the hefABC efflux system HefC
  KO
K18138  multidrug efflux pump
Organism
hef  Helicobacter pylori F16
Pathway
hef01501  beta-Lactam resistance
hef01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:hef00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    HPF16_0752 (hefC)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    HPF16_0752 (hefC)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hef02000]
    HPF16_0752 (hefC)
   01504 Antimicrobial resistance genes [BR:hef01504]
    HPF16_0752 (hefC)
Transporters [BR:hef02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   HPF16_0752 (hefC)
Antimicrobial resistance genes [BR:hef01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    HPF16_0752 (hefC)
SSDB
Motif
Pfam: ACR_tran MMPL Patched
Other DBs
NCBI-ProteinID: BAJ55349
LinkDB
Position
complement(776759..779839)
AA seq 1026 aa
MYKTAINRPITTLMFALAIVFFGTMGFKKLSVALFPKIDLPTVVVTTTYPGASAEIIESK
VTDKIEEAVMGIDGIKKVTSTSSKNVSIVVIEFELEKPNEEALNDVVNKISSVRFDDSNI
KKPSINKFDTDSQAIISLFVSSSSVPATTLNDYAKKTIKPMLQKIDGVGGVQLNGFRERQ
IRIYADPTLMNKYNLTYADLFNTLKAENVEIDGGRIVNSQRELSILVNANSYSVADVEKI
QVGNHVRLGDIAKIEIGLEEDNTFASFKDKPGVILEIQKIAGANEIEIVDRVYEALKHIQ
AISPNYEIRPFLDTTGYIRTSIEDVKFDLVLGAILAVLVVFAFLRNGTITLVSAISIPIS
VMGTFALIQWMGFSLNMLTMVALTLAIGIIIDDAIVVIENIHKKLEMGMNERKASYEGVR
EIGFALVAISAMLLSVFVPIGNMKGIIGRFFQSFGITVALAIALSYVVVVTIIPMVSSVV
VNPRHSRFYVWSEPFFKALESRYTKLLQWVLNHKLIIFIAVVLVFVGSLFVASKLGMEFM
LKEDRGRFLVWLKAKPGVSIDYMTQKSKIFQKAIEKHAEVEFTTLQVGYGTTQNPFKAKI
FVQLKPLKERKKEHELGQFELMSALRKELKSMPEAKGLENINLSEVSLIGGGGDSSPFQT
FVFSHSQEAVDKSVANLKKFLLESPELKGKIEGYHTSTSESQPQLQLKILRQNANKYGVS
AQTIGSVVSSAFSGTSQASVFKEDGKEYDMIIRVPDNKRVSVEDIKRLQVRNKYDKLMFL
DALVEITETKSPSSISRYNRQRSVTVLAQPKAGISLGEILTQVSKNTKEWLVEGANYRFT
GEADNAKETNGEFLIALATAFVLIYMILAALYESILEPFIIMVTMPLSFSGAFFALGLVH
QPLSMFSMIGLILLIGMVGKNATLLIDVANEERKKGLNIQEAILFAGKTRLRPILMTTIA
MVCGMLPLALASGDGAAMKSPIGIAMSGGLMISMVLSLLIVPVFYRLLAPIDDKIKRFYQ
NQKTLE
NT seq 3081 nt   +upstreamnt  +downstreamnt
atgtataaaacagcgattaatcgtcctattacgaccttgatgtttgctttggcgattgtc
ttttttgggactatgggttttaaaaaattgagcgtggcgcttttccctaaaattgatctg
cctacggtggtggttactacgacttatcctggagctagcgctgaaatcatagagagtaag
gtaaccgataagattgaagaagcggtgatggggattgatgggatcaaaaaggttacttcc
acgagttctaaaaatgtgagtattgttgtcattgaatttgagttagaaaagcctaatgaa
gaagccttaaacgatgtggttaataaaatttcttcggtgcgttttgatgattccaacatt
aaaaaaccctctatcaataaatttgataccgacagccaagccattatttcgttattcgtg
agcagttcaagcgtgcctgctacaacccttaatgactacgctaaaaaaaccattaaaccc
atgctccaaaaaatcgatggggtagggggcgtgcaactcaacggctttagggaacgccag
attaggatttatgcagatcccactttgatgaataaatacaacctcacttatgcggatctt
ttcaacacgcttaaagcggagaatgtggaaattgatggggggcgcattgtcaatagccaa
agggaattgtctattttagtgaatgcgaatagttacagcgtggcggatgtggaaaagatt
caagtgggtaatcatgtgcgtcttggcgatattgcaaagattgaaatcggcttggaagaa
gacaacacttttgcgagctttaaagacaaacccggtgtgattttagaaatccaaaagatt
gccggagcgaatgaaattgaaatcgtagatagggtgtatgaagctttaaaacacattcaa
gccattagccctaactatgaaatcagaccctttttagacaccacgggctatatccgcacc
tctattgaagatgtgaaatttgacttagttttaggggcgattttagcggttttagtggtg
tttgcgttcttgcgtaacggcacaatcactctcgtttcagcgatctctatccctatttct
gtcatggggacttttgcacttattcaatggatgggcttttcattaaacatgctcaccatg
gtggctttaacgctagcgatagggattatcattgatgatgcgatcgtggtgattgaaaac
atccataaaaagctagaaatgggcatgaacgaacggaaagcgagttatgagggggtgaga
gaaattggctttgctctagtggcgatttcagcgatgctgctctctgtttttgtgcctata
gggaacatgaaaggcattatcgggcgctttttccaaagctttgggatcacggtggcttta
gcgatcgctctatcgtatgtggtggtcgttacgattatccccatggtaagctcagtcgtg
gtcaatcctaggcattctcgtttttatgtgtggagtgagcctttttttaaggctttagaa
tctcgttataccaaactactccaatgggtgttaaaccacaagctcattatctttatagcg
gtggttttggtgtttgtgggttcgctttttgtggcttctaaattgggtatggagttcatg
ctgaaagaagataggggaaggtttttagtgtggcttaaggctaaaccgggcgtgagcata
gattacatgacacaaaagagtaagatctttcaaaaagcgattgaaaagcatgctgaggtg
gaatttaccaccttgcaagtgggttatggtaccacacaaaacccttttaaggctaaaatt
tttgtgcaactcaagcctttaaaagagcgcaaaaaagagcatgaattggggcaatttgag
ttgatgagcgctttaaggaaggagttaaaaagcatgcctgaagctaaaggtttagagaac
attaatctttctgaagtctctcttatagggggcggtggggatagttcgcccttccaaacc
tttgtgttttcccattctcaagaagcggtggataaaagcgtggcgaatttgaaaaaattc
ttattggaaagccctgaattaaaaggcaagatcgaaggctaccatacaagcacgagcgaa
tcgcaaccgcaactgcaactgaaaatcttaagacaaaacgccaacaaatacggcgtgagc
gctcaaactattggctcagtggtgagctctgctttctctgggacttctcaagcgagcgtg
ttcaaagaagatggtaaagaatacgacatgattattagagtgcctgataacaagcgcgtt
tctgtagaggacatcaaacgcttgcaagtgcgtaacaaatacgataaattgatgttttta
gacgctttagtggaaatcacagaaactaaaagcccgtccagcatttctcgctataaccgc
caacgcagcgttacggtgctcgctcagcctaaagcaggtatctctttaggggaaatttta
acgcaagtgagtaaaaacactaaagagtggctggttgaaggggcgaattacagatttacc
ggtgaagcggataacgctaaagagaccaatggggagtttttgatcgctctagcgacagcg
tttgtgttgatttatatgattttagcggcgttgtatgagtccattttagagccttttatt
atcatggttaccatgcctttaagcttttcaggggcgttttttgctctaggtttagtccat
cagcctttgagcatgttctctatgataggtttgatcttgctcattggtatggtgggtaaa
aacgccacgcttttaattgatgtggcgaatgaagagcgtaaaaaaggtttgaatatccaa
gaagccattttgtttgccggcaaaacccgtctgagaccgattttgatgacgaccattgcg
atggtttgcggcatgctgcctttagcgttggcgagtggggatggagcggcgatgaaatcc
cctatagggattgcgatgagtgggggcttaatgatttctatggtcttaagcttactcatt
gtgccggtgttttatcgccttctcgctcccatagacgacaaaatcaagcggttttatcaa
aaccaaaaaactttagaatga

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