Helicobacter felis: HFELIS_02250
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Entry
HFELIS_02250 CDS
T01375
Symbol
ispDF
Name
(GenBank) putative bifunctional enzyme ispD/ispF, IspDF
KO
K12506
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:
2.7.7.60
4.6.1.12
]
Organism
hfe
Helicobacter felis
Pathway
hfe00900
Terpenoid backbone biosynthesis
hfe01100
Metabolic pathways
hfe01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
hfe00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
HFELIS_02250 (ispDF)
Enzymes [BR:
hfe01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.60 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HFELIS_02250 (ispDF)
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
HFELIS_02250 (ispDF)
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Gene cluster
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Motif
Pfam:
YgbB
IspD
NTP_transf_3
EGF2_RECK
Motif
Other DBs
NCBI-ProteinID:
CBY82309
UniProt:
E7AD44
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All DBs
Position
complement(192122..193348)
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AA seq
408 aa
AA seq
DB search
MPKLKETKLKEIDFSVFKGMGVSLILAAAGQGRRFVEGLEGLENLKKQWILVHGMPLWQR
VYEQFARLGCFERIVIVVSNPVERVFVQQRLPSACVVVGGESRQESVQNALVHVESHFVV
VSDVARFGLDLRVLFNLFDTMQKQTLDGVAPAMPPSDTLVCGTPPWTLNRQEVRCVQTPQ
ICLTSSLKKAYGLGKFTDESSALLHLGARVEFIEGSAHLHKLTHRWDFAILAPLIDPPTQ
HTGMGFDTHAFELHKPLKLGGILIESADCQNLGLKAHSDGDVLLHALSDAILGAIKGGDI
GMYFSDQDPRFKNMDSAIMLQEIYALLQNMGYIVQSVDLNLLTEIPKIAPYRERICQNVA
NLLRIHPHQVNLKATTLEGLGFIGRKEGMGAQAVVQITSRPIDLHEKS
NT seq
1227 nt
NT seq
+upstream
nt +downstream
nt
atgccaaaattaaaagagacaaaattaaaagagatagattttagtgtttttaaaggcatg
ggagtctcgctaatcctagcagctgcaggacagggcaggcgttttgtggagggcctagag
ggcttagaaaacctcaaaaagcaatggattttagtgcacggcatgcccttgtggcagaga
gtgtatgagcaatttgcccgtttggggtgttttgagcgcattgttatcgtggtgagtaat
cctgtagagcgggtttttgtgcaacaacgcctacctagtgcctgcgtggtggtgggcgga
gaaagccgtcaagagagcgtgcaaaatgccctagtgcatgtagaaagccattttgtggtg
gtgagtgatgtcgcccgttttggactagatttgcgtgtgctgttcaatctttttgacacc
atgcaaaaacaaaccttagatggcgttgccccggctatgcctcctagcgatactcttgtt
tgtgggacacccccatggacactgaacagacaagaggtccgctgtgtgcagaccccccaa
atttgcttgacttctagcctgaaaaaagcctatggactaggaaaatttaccgatgagagc
agtgctttattgcacttgggcgcgcgggtagaattcatagagggaagcgcgcacctgcac
aaactcacccatcgttgggattttgctatattggccccccttatcgatccgccaactcag
catactggcatgggttttgacacgcacgctttcgagttgcacaaacccctcaagcttggc
ggaatcctcattgaatctgcagattgtcaaaatttaggactcaaagcccatagtgatggg
gatgttttattgcacgcgctcagtgatgcgatcttgggcgcgatcaagggaggggatatt
gggatgtattttagcgatcaagaccctcgttttaaaaatatggattcggcgatcatgctc
caagaaatttatgctctcttgcaaaacatgggctatattgtgcaaagtgtggatctcaat
ctcttgactgaaattccaaagatcgctccctatagagagcgtatctgtcaaaatgtcgct
aatttgttgcgcatacacccccatcaggttaatcttaaagccactactttggagggcttg
ggattcataggaagaaaggaaggcatgggcgcgcaggctgtggtgcaaatcacgagtcgc
cctatcgatctgcatgaaaaaagttga
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