KEGG   Candidatus Hydrogenisulfobacillus filiaventi: R50_2705
Entry
R50_2705          CDS       T08923                                 
Name
(GenBank) 5,10-methylenetetrahydrofolate reductase / Homolog of homocysteine-binding domain
  KO
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Organism
hfv  Candidatus Hydrogenisulfobacillus filiaventi
Pathway
hfv00270  Cysteine and methionine metabolism
hfv00450  Selenocompound metabolism
hfv00670  One carbon pool by folate
hfv01100  Metabolic pathways
hfv01110  Biosynthesis of secondary metabolites
hfv01120  Microbial metabolism in diverse environments
hfv01230  Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:hfv00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    R50_2705
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    R50_2705
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    R50_2705
Enzymes [BR:hfv01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     R50_2705
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     R50_2705
SSDB
Motif
Pfam: S-methyl_trans MTHFR
Other DBs
NCBI-ProteinID: CAB1130194
UniProt: A0A6F8ZJS5
LinkDB
Position
1:2493351..2495252
AA seq 633 aa
MEPQATELEALLADPRRTLIGDGALGTWLAAAGVAPEDQPWLVLRDPDRILDLHLAYLQA
GARLLETATFLANRVKLAALGREDIDVYTVNRRAAQLARHARDTFGEPAWVLGSLGPLGP
RVVLPGEEAGPADLPYETAYAAYREAVSGLVAGGVDGFIVETLSDLGTARAAVAAIRAES
ALPVVVTFAFSLEGTTLYGLTPEAAAEGVLDLPGGPPAVVGANCGTGPSPLLDAVLRMAP
ILRGHGIRLAAIPNAGQPHLHGQALEYPASPDYMATLVPALKAAGCAVIGGCCGTTPAHI
AAMAAADRREAEPVSGRLELAGGEERPADGGGPQPSPLESRLQAGRFVISVELDPPRGAN
PARLLAAARTLAAAGVDAVNVADSPMARVRMSAMATGRLIREAAGLDIILHFTTRDRNLM
GLESDLLGAYALGMQNILCLTGDPPALGDYAASTAVYDLDSVGLVQVLQRFKAGEDSFGH
SIGQPLRFLAGVGANPNHPDLKEEAVRVRRKLEAGADFIMTQPLYDAGRYLAWLDAVGPL
PVPVLVGVMPLVSYRQAEYLHHEVPGIDIPEAVREAMRQAGQDGARVGMELALAFLEALP
GNLAGIYLVPSFNKVEPLLPLIEAARRRYSRAG
NT seq 1902 nt   +upstreamnt  +downstreamnt
atggaaccacaggcgaccgagctggaagcattgctagccgatccccgccgcacccttatc
ggggacggggccctcggcacctggctggcggccgccggcgtggcccccgaggaccagccc
tggctggtgctgcgggatccggaccgcatcctggacctgcatctggcctatctccaggcc
ggggcccggctgctggaaaccgccaccttcctggccaaccgcgtcaagctggcggctttg
ggccgggaggacatcgacgtctacaccgtcaaccgcagggccgcccagctggcccggcac
gcgcgggacacgttcggggagcctgcctgggtgctaggctcgttaggccccctggggcct
cgcgtggtcctgccgggagaggaggcgggcccggccgacctgccctacgagacggcctat
gcggcgtaccgggaggcggtttccgggctggtggcgggaggcgtggacggctttatcgtg
gagaccctctccgacctcggcaccgcccgcgcggcggtggccgccatccgtgctgaaagc
gccctgccggtggtggtgacctttgccttctccctggaaggcaccaccctttatgggctg
accccggaagccgcggccgaaggggtgctggacctgcccggcggcccgccggccgtggtc
ggggccaactgcggtaccggccccagccccttgttggatgccgtcttgcgcatggccccc
atcctgcgcgggcacggcatccgcttggccgccatccctaacgccggccagccccatctg
cacggccaggccctggagtaccccgccagcccggattacatggccaccctggtaccggcg
ttgaaggcggccggctgcgcggtcatcggcggctgctgcggcaccaccccggcccacatc
gccgccatggctgctgccgaccgccgggaagcggaaccggtcagcggccggctggagctg
gcgggcggagaggagcggcccgcggacggcggcggcccccagccgtccccgcttgaaagc
cgcctccaggccggccgttttgttatcagtgtggagctggacccgccgcggggggccaac
cccgcccgcctgctggccgctgcgcgcaccctggcggcggcgggggtggacgccgtcaac
gtggccgactcccccatggcccgggtgcggatgagcgccatggccaccggccgactgata
cgggaggcggcggggctggacatcatcctgcatttcaccacccgcgaccgcaacctgatg
ggtctggagagcgacctgctgggggcttatgccctggggatgcagaacatcctctgcctg
accggtgacccgcccgccttgggggactacgccgcctccaccgccgtgtatgacctcgac
tcggtcggcctggtgcaggtgttgcagcggttcaaggcaggcgaggacagtttcggccat
agcatcgggcagccgctacgcttcctggccggggtcggggccaatcccaaccaccccgac
cttaaggaggaggcggtccgggtccggcgcaagctggaggccggggccgatttcatcatg
actcagcccctgtatgatgccggccgctacctggcctggcttgacgcggtcgggcctctg
ccggtgccggtgctggtgggggtgatgccgctggtctcctaccggcaggcggaatacctg
caccacgaagtaccgggcatcgacatcccggaggccgtgcgggaggccatgcgccaggcc
ggccaggacggggcgcgggtgggcatggaattggccctcgcctttctggaggccctgccc
ggcaacttggccggcatttacctggtcccttccttcaataaggtggaacccctgctcccc
ctcatcgaagccgcccggcggcgctattcccgcgccgggtga

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