Heterocephalus glaber (naked mole-rat): 101697947
Help
Entry
101697947 CDS
T02812
Symbol
Ikbke
Name
(RefSeq) inhibitor of nuclear factor kappa B kinase subunit epsilon
KO
K07211
inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:
2.7.11.10
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04620
Toll-like receptor signaling pathway
hgl04621
NOD-like receptor signaling pathway
hgl04622
RIG-I-like receptor signaling pathway
hgl04623
Cytosolic DNA-sensing pathway
hgl04625
C-type lectin receptor signaling pathway
hgl04657
IL-17 signaling pathway
hgl04936
Alcoholic liver disease
hgl05160
Hepatitis C
hgl05161
Hepatitis B
hgl05162
Measles
hgl05164
Influenza A
hgl05165
Human papillomavirus infection
hgl05167
Kaposi sarcoma-associated herpesvirus infection
hgl05168
Herpes simplex virus 1 infection
hgl05169
Epstein-Barr virus infection
hgl05171
Coronavirus disease - COVID-19
hgl05207
Chemical carcinogenesis - receptor activation
hgl05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
101697947 (Ikbke)
04621 NOD-like receptor signaling pathway
101697947 (Ikbke)
04622 RIG-I-like receptor signaling pathway
101697947 (Ikbke)
04623 Cytosolic DNA-sensing pathway
101697947 (Ikbke)
04625 C-type lectin receptor signaling pathway
101697947 (Ikbke)
04657 IL-17 signaling pathway
101697947 (Ikbke)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
101697947 (Ikbke)
09172 Infectious disease: viral
05161 Hepatitis B
101697947 (Ikbke)
05160 Hepatitis C
101697947 (Ikbke)
05171 Coronavirus disease - COVID-19
101697947 (Ikbke)
05164 Influenza A
101697947 (Ikbke)
05162 Measles
101697947 (Ikbke)
05168 Herpes simplex virus 1 infection
101697947 (Ikbke)
05167 Kaposi sarcoma-associated herpesvirus infection
101697947 (Ikbke)
05169 Epstein-Barr virus infection
101697947 (Ikbke)
05165 Human papillomavirus infection
101697947 (Ikbke)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101697947 (Ikbke)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101697947 (Ikbke)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hgl01001
]
101697947 (Ikbke)
Enzymes [BR:
hgl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
101697947 (Ikbke)
Protein kinases [BR:
hgl01001
]
Serine/threonine kinases: Other
IKK family [OT]
101697947 (Ikbke)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
ABC1
Kinase-like
Pkinase_fungal
APH
RH_dom
Motif
Other DBs
NCBI-GeneID:
101697947
NCBI-ProteinID:
XP_012934112
LinkDB
All DBs
Position
Un
AA seq
783 aa
AA seq
DB search
MQSTGNYLWHTDDLLGQGATASVYKARDKKSGELVAVKVFNTASYLRPREVQVREFEVLR
KLSHQNIVKLFAVEETVGAPWSGSGHRQPAGRGRDGTRGAERASGRRRPCGPRQGQQQRW
PESRAPLRVGGSSPSKPCVPPQGPGRQKVLVMEYCSGGSLLSVLESPENAFGLPEAEFLV
LLRCVVAGTNHLRENGVVHRDIKPGNIMRLVGEQGQSIYKLTDFGAARELDEDEKFVSVY
GTEEYLHPDMYERAVLHKPQQKAFGVTVDLWSIGVTLYHAATGTLPFVPFGGPRRNKEIM
YRIITEKPVGAIAGAQRRENGPLEWSHSLPITCQLSMGLQSQLVPILANILEVEEAKCWG
FDQFFAETSNILQRVVVHVFSLSQFILHHVYVHAHNTIAIFLEAVYEQTNVAPQHQEYLF
EGHFCVFDPSLSARHIGHTTARSPLTLFSTASDTPKGLTFRDPALDIPKFVPKVDPQADY
STAKGVLGASHQALRLARALLSGQELALRGLHWVMELLQATCRQTLEVIRIALLFLSSSL
ATERSSSMARMPEMPEIWELQRATELRSKLQTLATVLTKCSQDVAETQVSLSHLSLELAK
TRDQVHEDRSTQQIQSCLDKMYLIYKQFKKSRMRPGLGYNEEQIHKLDKVNFSHLAKRLL
QVFQEECVQKYQASLVAHCRWMREVQKARNQLRLAGWSVTTCNTEAQGAQENLSEILRRL
LQDRTKGAEASPSDPSPHPSAAPKDLVAHMQELCEEVKLLAFDLQDNNRVIERLSGVPAP
ADV
NT seq
2352 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcacaggcaactacctgtggcacacagatgacctgctggggcagggggccacg
gccagcgtgtacaaggcccgcgacaagaagtcgggtgagctagtggccgtgaaggtcttc
aacaccgccagctacctgcggccgcgcgaggtgcaggtgagggagtttgaggtcctgcgg
aagctcagccaccagaatatcgtcaagctcttcgcggtggaggagacggtgggtgcccct
tggtcagggtctggtcaccggcagccagcaggcagagggagggatggcacgcgcggagca
gagagggcttccgggaggaggcggccttgtgggccccggcagggacagcagcagaggtgg
ccggagagcagagcccctcttcgggttgggggctcctctccttccaagccttgcgtgcct
ccgcaggggcccggccggcagaaggtgctggtgatggagtactgctccggcgggagtctg
ctgagcgtgctggagagccccgagaacgccttcgggctgcctgaggccgagttcctggtg
ctgctgcgctgtgtggtggccggcacaaaccacctgcgggagaacggcgtcgtgcaccga
gacatcaagccagggaacatcatgcgcctggtcggggagcaggggcagagcatctacaaa
ctgacggacttcggggccgcgcgggagctggatgaggacgagaagttcgtgtctgtctac
gggacggaggagtacctgcacccggacatgtatgagcgggcggtgctgcacaagccccag
cagaaggcgtttggggtgacagtggacctctggagcatcggggtgaccctgtaccacgcg
gccactggcaccttgcccttcgtcccctttggtgggccgcgacgcaacaaggagatcatg
taccggatcatcacggagaagccggtgggggccatcgcaggggctcagaggcgggaaaac
ggaccactggagtggagccacagcctccccatcacctgccagctgtccatggggctgcag
agccagctggtgcccatcctggccaacatcctggaggtggaagaggccaagtgctggggc
ttcgatcagttctttgcggagacgagtaacatcctgcagcgggtcgtggtccacgtcttc
tccctgtcacagttcatcctgcaccacgtctatgtccacgcgcacaacacgatcgccatc
tttctggaggctgtgtatgagcagaccaacgtggccccccagcaccaagagtacctcttc
gagggtcacttttgtgtcttcgaccccagcctctcagcacggcacatcggccacacgact
gccagaagccccctgactctgttcagcacggccagcgacacccccaagggtctgaccttc
agggaccccgccttggacatccccaagttcgtccccaaagtggacccgcaggcagactac
agcactgccaagggcgtgctcggcgccagtcaccaggcactgcggctggctcgggccctg
ctcagcgggcaggagctggcccttcgtgggctgcactgggtcatggagctgctccaggcc
acatgcaggcagaccctggaggtcatcaggattgccctcctcttcctcagcagcagcctg
gccaccgagcggtccagcagcatggccaggatgcctgagatgcccgagatctgggaactg
cagagggctacagagctgaggtccaagctacagactttggctacagttctcaccaaatgt
tcccaagatgttgcagagacccaggtgagcctgagccacctgagcttggagctggcgaag
acccgggatcaggtacatgaagacagaagtacccagcagattcagagctgcttggacaag
atgtacctcatctacaaacagttcaagaaatctaggatgaggccagggctcggctacaat
gaggagcagatccacaagctggataaggtgaatttcagccatttagccaagaggctcctg
caggtgttccaggaagagtgtgtgcagaagtatcaggcgtccttggtcgcgcactgcagg
tggatgagagaggtgcagaaggcccggaaccagctgcgcctggccggctggtctgtgacc
acctgcaacacagaagcgcagggagcccaggagaacctgagcgagatccttcggcggctc
ctccaggacaggacgaagggggccgaggcctcaccatccgacccgtctcctcaccccagc
gctgctcccaaagacctggtcgcgcacatgcaggagctctgcgaggaggtgaagctgctg
gcctttgatctccaggacaacaaccgcgtcatcgaacggttgagtggagtcccagctcct
gctgatgtctga
DBGET
integrated database retrieval system
