Heterocephalus glaber (naked mole-rat): 101698314
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Entry
101698314 CDS
T02812
Symbol
Fasn
Name
(RefSeq) fatty acid synthase
KO
K00665
fatty acid synthase, animal type [EC:
2.3.1.85
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl00061
Fatty acid biosynthesis
hgl01100
Metabolic pathways
hgl01212
Fatty acid metabolism
hgl04152
AMPK signaling pathway
hgl04910
Insulin signaling pathway
hgl04936
Alcoholic liver disease
Module
hgl_M00082
Fatty acid biosynthesis, initiation
hgl_M00083
Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
101698314 (Fasn)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
101698314 (Fasn)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
101698314 (Fasn)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101698314 (Fasn)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
hgl01004
]
101698314 (Fasn)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hgl04147
]
101698314 (Fasn)
Enzymes [BR:
hgl01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.85 fatty-acid synthase system
101698314 (Fasn)
Lipid biosynthesis proteins [BR:
hgl01004
]
Fatty acid synthase
Animal type
101698314 (Fasn)
Exosome [BR:
hgl04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
101698314 (Fasn)
Exosomal proteins of breast milk
101698314 (Fasn)
Exosomal proteins of colorectal cancer cells
101698314 (Fasn)
Exosomal proteins of bladder cancer cells
101698314 (Fasn)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Acyl_transf_1
ketoacyl-synt
Thioesterase
KR
KAsynt_C_assoc
Ketoacyl-synt_C
FAS_pseudo-KR
ADH_zinc_N
ADH_zinc_N_2
PKS_DH_N
PP-binding
Methyltransf_12
adh_short
Methyltransf_23
Methyltransf_31
Methyltransf_11
PS-DH
Thiolase_N
DUF7080
Methyltransf_25
ACP_syn_III
Motif
Other DBs
NCBI-GeneID:
101698314
NCBI-ProteinID:
XP_004861077
UniProt:
A0A0N8EUW9
LinkDB
All DBs
Position
Un
AA seq
2506 aa
AA seq
DB search
MEEVVIAGMSGKLPESDNLDEFWANLVGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSKF
DASFFGVHPKQAHTMDPQIRLLLEVTYEAIVDAGINPALLRGTNTGVWVGVSGSEASEAL
SRDPETLVGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLMALQNAYEAIRSGQC
PAAIVGGINVLLKPNTSVQFMKLGMLSPEGMCKSFDETGSGYCRSEAVVAVLLTKKSLAR
RVYATILNAGTNTDGSKEQGVTFPSGEAQEQLIRSLYLPAGLAPESLEYIETHGTGTKVG
DPQELNSITRALCASRQDPLLIGSTKSNMGHPEPASGLAALAKVLLCLEHGLWAPNLHFH
TPNSEIPALSDGRLQVVDRPLPVHGGIVSINSFGFGGSNVHVILQPHTKQPSPPAPHAAL
PRLLRVSGRTLEAAQSLLDQGCQHSQDLTFVSMLNDIMATSLSTMPFRGYAVLGVEGGAQ
EVQQVPSSKRPLWFICSGMGTQWYGMGVSLMHLGGFRDSILRSDEALKPVGLKVSDLLLS
TKKNTFDDIVHAFVSLTAIQIALLDLLTSMGLRPDGIIGHSLGEVACAYADGCVSQEEAV
LAAYWRGQCVKEASLPSGTMAAVGLSWEECKQRCPSGIVPACHNSEDTVTISGPQAAVSK
FVEQLKQEGVFAKEVQTGGIAFHSYFMEAIAPALLQALKKVIKEPRPRSARWLSTSIPEA
QWQGGLAHTFSAEYNVNNLVSPVLFQEALWHIPEHAVVVEIAPHALLQAVLKRGLKSSCT
IVPLMKRDHKNNLEFFLTNIGKLHLAGIDTNPDALFPPVEFPAPRGTPLISPHIKWDHSQ
TWDVPTAEDFPNGSGSSSATVYNIDTTPESPDHYLVDHCIDGRVLFPATGYLVLVWRTLA
RSLGLPLEQTPVVFEGVTLHQATILPNTGTVALEVRLLEAACTFEVSHNGNLIVSGKVYQ
WEDPDRKLFDHPEGLGPMEPVPTSCLSPADVYKELRLRGYNYGPHFQGIFEASLRGERGK
LLWRDNWVTFMDTMLQAAILGKSQRILSLPTRVTDMRIDPAVHLQKVHMLQDSTQVVDFV
VSSALSRIVAGGVHILQLHTTSAPRRQQEHTMPILERFCFTPHVEAGCLSESAALQEELQ
LCRGLARTLQAKAAQQGLKMVVPELDGARAPQEPPQQGLPRLLAAACRLQLNGNLQQALA
QERALLPEDPLLSGLLNSPVFKACLDTALENLPSPKMKVVEVLAGDGHLYSRVSALLNTH
PMLQLDYTATDRHPQALEAAQDKLKQHDVAQGQWDPADPVPSSLGAADLLVCNSAVASLG
DPALALTNMAAALREGGFLLLHTVLRGHTLGETLAFLTSEPYSGPTLLRQDEWESLFSKT
ALHLVGLKTSFYGSAIFLCRRPAPQDSPIFLPVEDTSFRWVDSLKNILAEVSPRPVWLTA
LGCPTSGVVGMVNCLRKEPGGHRIRCILLSNLSSTSRVPKMDPGSAELQKVLEKDLVMNV
YRDGAWGAFRHFLLGQDKPEEQTTHAFVNVLTRGDLSSIRWVCSPLKYAQPTSPETQLCT
VYYASLNFRDIMLATGKLSADAIPGKSLNRDCLLGMEFSGRDALGRRVMGLVPSEGLATS
VLVPSAFLWDVPSSWTLEEAGSVPVVYSTAYYALVVRGRLRHGESVLIHSGSGGVGQAAI
AVALSLGCRIFTTVGSAEKRAYLQSRFPQLDETSFANSRDTSFEQHVMLHTGGKGVDVVL
NSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHPLGMAIFLKNVTFHGILLDALMEEDNP
QWREVFGLLQAGIRDGVVQPLKCTVFPRAKVEDAFRYMAQGKHIGKVLVQVQEEERESGL
QGAQPAPVAAISKTFCPPHKTYVIAGGLGGFGLELAQWLLQRGARKLVLTSRSGIRTGYQ
AKQVSEWRSRGVQVLVSTRDASSLEGARALLSEAAQLGPVGGVFNLAVVLRDAMLEGQTP
EQFQDVSRPKYSGTLNLDRVTREACPQLDHFVAFSSVSCGRGNMGQSSYGFANSAMERIC
EQRRHDGLPGLAVQWGAIGDVGILLDVMGGDDIVVGGTVPQRIASCLEVLDLFLQQPHAV
LSSFVLAEKAAALRDSKGQLDLMQAVAHILGIRDLAGMNLDISLADLGLDSLMSVEVRQT
LEREYDLVLSMREVRQLTLRKLQELSSRPSPDRELASPKAKDGSQVRPQAQLNLSTLLVN
PEGPTLTRLNLVQNTERPLFLVHPIEGSTTVFQNLAAKLSVPTYGLQCTQAAPLDSIQSL
AAYYIDCIKQVQPEGPYRLAGYSYGACVAFEMCSQLQAQQGPAPAHHSLFLFDGSHTYVL
AYTQSYRAKMTPGCEAEAEAEAVCFFVQQFTDAEHGRVMEALLPLRSLEERVAAAVDLIT
QSHQGLGRRELSFAALSFYHKLRAIEQYTPKAKYHGNVTLLRAKTGGAYGEDLGADYNLS
QVCDGKVSVHVIEGDHRTLLEGSGLESIINIIHSSLAEPRVSVREG
NT seq
7521 nt
NT seq
+upstream
nt +downstream
nt
atggaggaggtagtgattgctggtatgtccgggaagctgcccgagtcagacaacttggat
gagttctgggccaacctcgtcggtggcgtggacatggtcacagacgacgaccggcgatgg
aaggccgggctttatggcctgccccggcggagcggcaagctgaaggacctatccaagttc
gatgcttccttcttcggtgtccaccccaagcaggcgcacacaatggacccccagatccgg
ctgctgttagaagtcacctatgaggccattgtggacgcaggtatcaacccagccttgctc
cgagggacaaacaccggtgtctgggtgggtgtgagtggctcagaggcttcagaggccctg
agccgagatcccgagacacttgtcggctacagcatggtgggctgtcagcgcgcaatgatg
gccaaccgcctctccttcttctttgacttcaaagggcccagcatcgccctggacacagcg
tgctcctccagcctgatggccctgcagaatgcctacgaggccatccgcagcgggcagtgc
ccagctgccatcgtgggtggtatcaatgtgttgctcaagcccaacacctccgtgcagttc
atgaagttgggcatgcttagccccgaaggcatgtgcaagtccttcgacgaaacagggagt
ggatactgccgttcagaggctgtagtcgctgtcttgctgaccaagaagtccctggcccgg
cgggtgtatgccactatcctgaatgctggcaccaacacagatggctccaaggaacaaggt
gtgaccttcccctctggagaggcccaggagcagctcatccgctccctgtacctgccggct
gggctggcaccggagtccctggagtacattgaaacccatggcacgggcaccaaggtgggc
gacccccaggagctgaatagcatcaccagggccctgtgcgcctcccgccaggacccgctg
ctgattgggtccaccaagtccaacatggggcaccccgagcctgcctcagggcttgcagct
ctggccaaggtgctgctgtgcctggagcatgggctctgggcccccaacctgcacttccat
accccgaactctgagatcccagccctgagtgacgggcggctgcaggtggtagaccggccc
ctgcctgttcatggtggcattgtgagcatcaattcctttggcttcggagggtccaacgtg
cacgtcatcctccagccccacacgaagcagccctcaccacctgccccccatgctgccctg
ccccgcctgctgcgggtcagtgggcgtaccctcgaggctgcgcagagcctgctggaccag
ggttgccagcacagccaggacctaaccttcgtgagcatgctcaatgacatcatggccact
tcactgtcaaccatgcccttcaggggctatgccgtgctgggtgtggagggcggtgcccag
gaagtgcagcaggtgccttccagcaagcgcccgctctggttcatttgctcagggatgggc
acacagtggtacggaatgggagtgagccttatgcatctgggtggcttccgtgactccatc
ctgcgctctgatgaggccctgaagccagttggactgaaggtgtccgacctgctgctgagc
acaaagaaaaacacctttgatgacattgtccatgccttcgtgagcctcaccgccatccag
attgctctcttagacctgctgacttccatgggcctgagacctgacgggatcattgggcac
tccctgggggaggtggcctgtgcctatgccgatggctgtgtctcccaggaggaggctgtg
cttgcagcctactggagaggccagtgtgtcaaggaggccagcctcccgtcaggcaccatg
gctgctgtgggcttgtcctgggaggagtgtaaacagcgctgcccttctggcattgtgccc
gcctgccacaactccgaggacacagtgaccatctcgggacctcaggctgcagtgagcaag
ttcgtggagcagctgaagcaggagggagtgttcgccaaggaggtgcagaccggcggcata
gccttccactcctacttcatggaggccattgcacctgcactgctgcaggctctcaagaag
gtgatcaaggagcctcggccgcgctccgcccgctggctcagcacttccattcctgaggcc
cagtggcagggcggcctggcccacaccttctccgctgagtacaacgtcaacaacctggtg
agcccagtgctgttccaggaggccctgtggcacatccctgagcatgccgtggttgtggag
atcgcaccccacgccctgctgcaggctgtcctgaagcggggcctgaagtccagctgcacc
attgtgcccctgatgaagcgggaccacaagaacaacctcgagttcttccttaccaacatc
ggcaagctccacctcgcaggcatcgacaccaaccctgatgccttattcccacctgtggag
ttcccagcgccccgaggaacgcccctcatctccccccacatcaagtgggaccacagccag
acctgggacgtgccaaccgcagaggatttcccgaatggctcaggctcttcctccgccacc
gtttataacattgacaccactcccgagtcccctgaccactacttggtggaccactgcatc
gatggccgcgtgctcttccctgccaccggctacctggttcttgtctggaggacgctggct
cgaagcctgggcctgcctttagagcagacccccgtggtgttcgagggtgtgacgctgcac
caggccaccatcctgcccaacacagggaccgtggccctggaggtgcggttgctggaggcc
gcctgcactttcgaagtgtctcataacggcaacctgatcgtgagtgggaaggtgtaccag
tgggaggaccccgaccgcaagctcttcgatcacccagaaggcctgggtcccatggagcct
gtgcctacttcctgtctgtccccggcggacgtgtataaggagctgcggctgcgtggctat
aactacggcccccacttccagggcatcttcgaggccagtctcagaggtgagcggggcaag
cttctctggagagacaactgggtgacgttcatggacaccatgctgcaggcggccatcctg
ggcaagagccagcgcatcctgagcctgcccacccgtgtcactgatatgcgcatcgacccc
gccgtccacctgcagaaggtgcacatgctgcaggacagcacccaagtggtcgacttcgtg
gtgagctccgctctgagcagaatagtggctggcggggtccacatcttgcagctccacacg
acgtcagccccacggcggcagcaggagcacacgatgcccatcctggagaggttctgcttc
acgccccacgtggaggcggggtgcctgtctgagagcgcggccctgcaggaggagctgcag
ctgtgcaggggcctggcacggacactgcaggccaaggcggcccagcaggggctgaagatg
gtggtgcctgagctggatggggcccgggcgccccaggaacccccacagcagggcctgccc
cgtctgctggcggctgcctgtcggctgcagctgaatggaaacttgcagcaggcactggcc
caggagagagccctgctgcctgaggaccccctactcagcggcctcctgaactccccagtg
ttcaaggcctgcttggacacagccctggagaacctgcccagcccgaagatgaaggtggtg
gaggtgctcgctggcgacggtcacctgtattcccgcgtctcagccctgctaaacacccac
cccatgctgcagctggactacacagccactgaccgtcacccccaggccctggaggccgcc
caggacaagctgaagcagcatgacgttgctcagggccagtgggaccctgcggaccctgtc
cccagcagtctgggcgcagcagacctcctggtgtgcaacagcgctgtggccagcctgggg
gacccggccctggccctgaccaacatggcagctgccctcagggagggcggctttctgctg
ctgcacactgtgctcagagggcacaccctcggggagaccctggccttcctcacctcggag
ccgtacagcgggcccacgctcctaagacaggatgagtgggagagtctcttctccaagacg
gcactgcacctcgtgggcctaaaaacttccttctacggctctgcgatcttcttgtgccgc
cggcccgccccacaggacagccctatcttcctgccggtggaggacaccagcttccgatgg
gtggactctctgaagaacattctggctgaggtgtccccccgccccgtgtggctgacagcc
ctgggctgccccacctcgggtgtggtgggcatggtgaactgtctccggaaggagcccggc
gggcaccggatccggtgcatcctgctgtccaacctcagcagcacgtctcgtgtccccaag
atggaccctggctctgcagagctgcagaaggtgctggagaaggatctggtgatgaatgtg
taccgggatggcgcctggggtgccttccgccatttcctcctggggcaggacaagcctgag
gagcagacaacgcacgccttcgtgaatgtcctcactcgtggggacctctcctccatccgc
tgggtctgctccccgctgaagtacgcgcagcccacgagccctgaaacacagctctgcact
gtttactatgcctcactcaacttccgggacatcatgctggccacgggcaagctgtccgcc
gatgccatcccagggaagtcactcaaccgggactgcctgctgggcatggagttctcaggt
cgtgatgctctgggccggcgtgtgatggggctggtgccctctgaaggcctggccacctct
gtcctggtgccgtcagccttcctctgggatgtgccctccagctggacactggaggaggcg
ggctccgtgcctgtggtctacagcaccgcctactacgcgctcgtggtgcggggccgccta
aggcacggggagtctgtgctcatccactcgggctcaggcggggtaggccaggccgccatc
gctgtcgccctcagcctgggctgccgcatcttcaccaccgtgggctcggctgagaagcgg
gcctacctccagtccaggttcccccagctggacgagaccagcttcgccaattcgagggac
acgtctttcgaacagcatgtgatgctgcacacgggcgggaaaggcgttgatgtggtcctc
aactccctggcggaagagaagctgcaggccagcgtgaggtgcctggcccagcacggccgc
tttctggagattggcaaatttgacctttccaacaaccacccgcttggcatggccatcttc
ctgaagaacgtcactttccacgggatcctgctggacgcactcatggaggaggacaacccc
cagtggcgagaggtgtttggcctcctgcaggctggcatccgcgacggagtggtgcagccc
ctcaagtgcaccgtgttccccagggccaaggtggaggatgccttccgctacatggcccag
gggaagcacattggcaaagtccttgtccaggtacaagaggaagagcgagagtccgggctg
caaggagcacagccagcccccgtggctgccatctccaagactttctgtccgccgcacaag
acctacgtcatcgcagggggcctgggcggcttcggcctcgagctggcccagtggctgctg
cagcggggggcccggaagcttgtgctgacctctcgctctggcatccgcacaggctaccag
gccaagcaggtcagcgagtggaggagccggggcgtgcaggtgctggtgtccacccgagac
gccagctcgctggagggggcccgtgccctcctgtccgaggccgcacagcttgggccggtc
ggaggagtctttaacctggctgtggtcctgagggacgccatgctggagggccagactcca
gagcagttccaggacgtcagcaggcccaagtacagcggcacgctcaacctggacagggtg
acccgagaagcctgcccgcagctggaccacttcgtggccttctcctcggtgagctgcggg
cgtggcaacatgggtcagagcagctacggcttcgccaactccgccatggagcgcatctgt
gagcagcgccggcacgatggcctcccaggcctcgccgtgcagtggggcgccattggcgac
gtgggcattttgctggacgtgatgggtggcgacgatatcgtcgtgggcggcacggtgccc
cagcgcattgcctcttgcctggaggtgctggacctcttcctgcagcagccccacgccgtc
ctgagcagcttcgtgctggccgagaaggctgcggccctcagggacagcaaaggccagctc
gacctgatgcaggccgtggcccacatcctgggcatccgagacttggctggaatgaacctg
gacatctcactggcggacctgggcctggactcgctcatgagcgtagaggtgcgccagacc
ctggagcgggagtatgacctggtgctgtccatgcgtgaggtgcgacagctcacactgcgg
aagctgcaggagctgtcctccaggcccagcccagacagagagctggcatcccccaaggcc
aaggatggcagccaggtgcggccacaggcccagctgaacctgagcacactgctggtgaac
cccgagggccccaccctgactcggctcaacttagtccagaacacggaacggccactcttc
ctggtgcaccccattgagggctccaccaccgtgttccaaaacctggccgccaagctgagc
gtgcccacctacggcctgcagtgcacccaggctgccccactggacagcatccagagcctg
gccgcctactacatcgactgcatcaagcaggtgcagcccgaagggccctaccgcctggcc
ggctactcctacggggcctgcgtggccttcgagatgtgctcccagctgcaggcccagcag
ggcccggcccctgcccaccacagcctcttcctgtttgacggctcgcacacctacgtgctg
gcctacacccagagctaccgcgccaagatgacccctggctgcgaggccgaggccgaggcg
gaggctgtgtgcttcttcgtgcagcagttcaccgacgcggagcacggcagggtgatggag
gcgctgctgcccctgaggagcctggaggagcgcgtggctgccgccgtggacctcatcacc
cagagccaccagggcctgggccggcgggagctgagctttgctgccctgtccttctaccac
aagctgcgcgccatcgagcagtacacgccgaaggccaagtaccacgggaacgtgacgctg
ctgcgggccaagacgggaggggcctacggcgaggacctgggcgccgactacaacctctcg
caggtgtgtgacgggaaggtgtccgtgcatgtcatcgagggcgaccaccgcacactgctg
gagggcagcggcctggagtccatcatcaacatcatccacagctctctggccgagcctcga
gtgagcgtgcgggaagggtag
DBGET
integrated database retrieval system
