Heterocephalus glaber (naked mole-rat): 101702123
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Entry
101702123 CDS
T02812
Symbol
Alox12
Name
(RefSeq) arachidonate 12-lipoxygenase, 12S type
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl00590
Arachidonic acid metabolism
hgl01100
Metabolic pathways
hgl01523
Antifolate resistance
hgl04726
Serotonergic synapse
hgl04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
101702123 (Alox12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
101702123 (Alox12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101702123 (Alox12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101702123 (Alox12)
Enzymes [BR:
hgl01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
101702123 (Alox12)
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Paralog
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Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
101702123
NCBI-ProteinID:
XP_004857402
UniProt:
G5B660
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All DBs
Position
Un
AA seq
663 aa
AA seq
DB search
MGRYRIRVATGAWLFSGSHNRVRLWLVGTLGEVELEPQLRLARGEEEEFDLEVPEDLGPL
QFVRLCKQHSLVDDAWFCDRITVQGPGACTEAAFPCYCWVQGEGVLSLPEGTARLAGDNT
LDVFQKHREKELKERQQIYRWATWKKGLPLTIAADCKDDLPPNMKFHEDKRLDFECTLKA
RVAEMVLKRVYTLLSHWNRLEDFDQIFWGQKSALAEKVHQCWQDDELFGYQFLNGANPMM
LRRTTSLPTRLVLPSGTEELQAQLEKELQNGSLFEADFILLDGIPANVIRGEKQYLAAPL
VMLKMEPSGKLLPMVIQIQPPNSSSPTPALFLPSDPPLAWLLAKSWVRNADFQLHQLQYH
LLNTHLVAEVIAVATMRCLPGLHPIYKLLIPHIRYTMEINTRARTQLISENGIFDQAVNT
GGGGHVQLLHQAMAQLTYSSLCPPNDLADRGLLGIPSALYAHDALRLWEIIARYVEGIVH
VFYQRDDVVRADPELQAWCREITEVGLCKAQDRGFPISFQSQDELCHFLTMCIFTCTAQH
GAINQGQLDWYSWVPNAPCTMRMPPPTIKEDVTMATVMGSLPDVQQSCLQMTITWHLGRL
QPDMVPLGHHKENYFSGPKAKAVLRQFQTDLKNLENEITARNEQLDLPYEYLKPSHIENS
ITI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcattcgcgtggccactggggcctggctcttctctgggtcgcacaac
cgcgtgcggctctggctggtcgggacgctcggggaggtggagctggagccacagctgcgg
ctggcgcggggtgaggaggaggagtttgacctcgaggttcctgaggacttggggccgctg
cagttcgtgaggttgtgcaaacagcactcgctggtggacgacgcgtggttctgcgaccgc
atcacggtgcagggcccgggagcctgtacggaggccgccttcccgtgctactgctgggtg
cagggtgagggcgtcctgagcctgcccgagggcaccgcccgcctggcaggagacaacacc
ttggatgtcttccagaagcatcgagagaaggaactgaaggaaagacaacagatctaccgc
tgggccacctggaagaaagggttacccctgacaatagctgcagactgtaaggatgatcta
cctccaaatatgaaattccatgaggacaagaggctggactttgaatgcacactgaaggca
agggttgcggagatggtcctcaaacgtgtttacaccctcttgagccactggaaccgccta
gaagactttgatcaaatcttctggggccagaagagtgccctggctgagaaggttcaccag
tgctggcaggatgatgagctttttgggtaccagttcctcaatggcgcaaaccccatgatg
ttgagacgcaccacctctctgcccaccaggctggtgctgccctcagggacagaggagctt
caggcccagttggagaaagaactccagaatggttccctgtttgaggctgactttatccta
ctggatggaattccagccaatgtgatccgaggggagaagcagtacctggctgcccccctt
gtcatgctgaagatggagcccagtgggaagctgctacccatggtcatccagattcagcct
cccaattccagctctccaaccccagcactgttcctgccctcagatcctccacttgcctgg
ctcctggccaagtcctgggtccgaaatgcagatttccaactgcaccagctccaatatcat
ttgctgaacactcatctggtggctgaggttattgccgttgccactatgaggtgcctccca
ggactgcaccctatctacaagctcctgatccctcatatccgctacactatggaaatcaac
acgagggcccggacccaactcatatcagagaatggaatatttgaccaggcagtaaacaca
ggtggagggggccatgtgcagttgctccatcaggcaatggctcagctgacctacagctcc
ctctgtcctcctaatgacctggctgaccggggcctgctgggaatcccaagtgctctctat
gcccacgatgctttacggctttgggagatcattgcccggtatgtagaggggattgtccat
gtcttctaccagagggatgacgttgtgagggcggaccctgagctgcaagcgtggtgtcgg
gaaatcactgaggtggggctgtgcaaagctcaggaccgaggtttccctatctccttccag
tcccaggatgaactctgccatttcctaaccatgtgtatcttcacatgcactgcccagcac
ggggccatcaaccaggggcagctggactggtattcctgggtccctaatgccccatgcaca
atgcggatgcccccacctaccatcaaggaagatgtgacaatggccactgtgatggggtca
ctacctgatgtccagcagtcctgtcttcaaatgaccatcacatggcatctgggtcgcctt
cagccagatatggtacctctggggcatcacaaagaaaactatttctcaggtcccaaagcc
aaagctgtgctaaggcaattccaaacagatctgaaaaacctggaaaatgagattacagcc
cggaatgaacaacttgacctgccttatgaatacctaaaacccagccacatagagaacagt
atcaccatctaa
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