Heterocephalus glaber (naked mole-rat): 101703312
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Entry
101703312 CDS
T02812
Symbol
Alk
Name
(RefSeq) anaplastic lymphoma receptor tyrosine kinase
KO
K05119
anaplastic lymphoma kinase [EC:
2.7.10.1
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl05200
Pathways in cancer
hgl05223
Non-small cell lung cancer
hgl05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101703312 (Alk)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101703312 (Alk)
09162 Cancer: specific types
05223 Non-small cell lung cancer
101703312 (Alk)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hgl01001
]
101703312 (Alk)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
hgl04090
]
101703312 (Alk)
Enzymes [BR:
hgl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101703312 (Alk)
Protein kinases [BR:
hgl01001
]
Receptor tyrosine kinases (RTK)
ALK family
101703312 (Alk)
CD molecules [BR:
hgl04090
]
Proteins
101703312 (Alk)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
MAM
ALK_LTK_GRD
Ldl_recept_a
FXa_inhibition
Motif
Other DBs
NCBI-GeneID:
101703312
NCBI-ProteinID:
XP_004839304
UniProt:
A0AAX6NXV7
LinkDB
All DBs
Position
Un
AA seq
1615 aa
AA seq
DB search
MGALGLLWLLLLLSAAARGSGQRAGSPAAGPPLQPREPLSYSRLQRKSLAVDFVVPSLFR
VYARDLLLPPPPPPAGPRTGRPEARGWLALDCAPLLRLLGPLPGLPRTAGHPSPSPAAAP
ALSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPPEGAAAGLLQFNLSELFSWWIHHG
EGRLRIRLMPEKKASELGRVGRLSSAIRASQPRLLFQIYRTGHSTLESPTNMPSSPDYFL
WNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHDLGNQSWSWRRVPSEEASQMD
LLDGPEAERSKEMPRGSFLLLNTSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYI
AQLLPHNEASREILLVPTPGKHGWTVLHGRVGRPENPFRVALEYISSGNRSLSAVDFFAL
KNCSEGTSPGSKMALQSSFACWNGTVVQLGQACDFHRDCAQGEDEGQLCNQLPAGFYCNF
EDGFCGWTQGTLSPHAPQWQVGTLKDARSWDHQDHALLLSTTDVPSPESATVTSATFPAP
IKNSPCELRMSWLIRGVLRGNVSLVLVENKTGKEQSRMVWHEATNEGLSLWQRTVLPLLN
VSDRFWLQMVAWWGQGSRATVAFDNISISLDCYLTISGEDKVPQTEEPKSRNLFERNISK
EPKSWENIPRQTPIFDPTVHWLFTTCGASGPHGPTQTQCHNAYQNSNLSVTVGSEGPLKG
IQIWKVPATDTYSISCYGAAGGKGGKNTMIRSHGVSVLGIFNLEKDDTLYILVGQQGEDA
CPSTNQLIQRVCIGESNVIEEEIRVNRSVREWAGGGGGGGGATYVFKMKDGVPVPLIIAA
GGGGRAYGAKTDTFHPERLENNSSVLGLNGNSGAAGGGGGWDDNTSLLWAGKSLLEGATG
GHACPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEMDGEDGVSFISPL
GVLYTPALKVMEGHGEVNIKHYLNCSHCEVDECHLDPESHKVICFCDHGTVLAEDGVSCI
VSPTPEPHLPLSLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQSPEYKLSK
LRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDP
SPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAGG
DLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGS
GRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEI
FSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILER
IEYCTQDPDVINTALPVEYGPPVEEEEKVPVRPEDPEGMPPLLLSPGQAPRGEERVPVPA
VPPPAPASSSGKAVRKPAATRGPAAGGGHVNMAFSQANPPPELRRIQGSRNKPTSLWNPT
YGSWFTEKPAKKNSAPAKKEPHQRGGLGSEGSCTVPAASSAAGRLPGASLLLEPSSLPAS
VKEVPLFRLRHFPCGNVNYGYQQQGLPLEVTTAPGAGHYEDAILKNKSNASQPGP
NT seq
4848 nt
NT seq
+upstream
nt +downstream
nt
atgggcgccctcgggctcctgtggctcctgctgctcctatcggcggccgcccggggctcc
ggccagcgcgcggggtccccggccgcagggccgccactgcagccccgggagccgctcagc
tactcgcgcctgcagaggaagagtctggcggtggacttcgtggtgccctcgctcttccgc
gtctacgcccgcgacctgctgctgccgccgccgccgccccccgcggggcccaggactggc
cggcccgaggcgcgcggctggctggccttggactgcgccccgctgctcaggcttctgggg
ccgctgcccgggctcccccggacagcaggccacccctcgccgtcccccgccgcggcgccg
gcgctgtccagggtgctgaagggcggctcagtccgtaaactccggcgcgccaagcagctg
gtgctggagctgggcgaggaggcgatcctggagggctgtgtcgggcctccagagggagcg
gctgccggactgctccagttcaacctcagcgagctgttcagctggtggattcaccacggc
gaagggcgactgagaatccgcctaatgcccgagaagaaggcgtcggaactgggcagagtg
gggaggctgtcctcggcgatccgcgcctcccagccccgccttctcttccagatctaccgg
accggtcatagcaccttggagtcaccaacaaacatgccttcttctcctgattattttttg
tggaatctgacctggataatgaaagactccttccctttcctgtctcatcgcagccgatat
ggtttggagtgtagctttgacttcccctgtgagctggaatattctcctccactgcatgac
cttgggaaccagagctggtcctggcgccgtgtgccctctgaggaggcctcccagatggac
ttgttggatggacctgaggcagaacgttctaaggagatgcccagaggctctttcctcctc
ctcaacacctcagcagactccaaacacaccattctcagcccatggatgaggagcagcagt
gagcactgtacgctggctgtctctgtgcacaggcacctgcagccgtctgggaggtacatc
gcccagctgctgccccacaatgaggcctcgagagagattctcctggtacccacaccaggg
aagcacggctggacagtgctgcacggaagagtcgggcgcccagagaaccccttccgagtg
gccctggaatacatctccagtggaaaccgaagtctgtctgcagtggacttttttgccctg
aagaactgcagtgaaggaacgtccccaggctccaagatggccctgcagagttccttcgcc
tgttggaatgggacagtcgtccagctcgggcaggcctgcgacttccaccgggactgcgcc
cagggagaagatgagggccagctgtgcaatcaacttcctgctggcttctactgcaacttt
gaggatggtttctgtggctggacccaaggcaccctctcgccccatgcgccccagtggcag
gtcgggaccctgaaggatgcccggtcctgggaccaccaagaccatgccctgttgctcagc
accaccgatgtccccagtcctgaaagtgctaccgtgaccagtgccacatttcctgcaccg
ataaagaactctccgtgtgagctcagaatgtcctggctcatccgtggagtcttaagggga
aacgtgtccttggtgctggtggagaacaaaacagggaaggagcaaagcaggatggtctgg
cacgaggccaccaatgaaggcttgagcttgtggcagcggacagtgcttcccctcctcaat
gtgtctgacaggttctggctgcagatggtcgcatggtgggggcaaggatccagagccacc
gtggcttttgacaatatctccatcagtctggactgctacctcaccatcagtggggaggac
aaggtgccccagactgaagaacccaaatcaagaaatctgtttgagagaaacataagcaag
gagccaaagtcctgggaaaacataccaaggcagactcccatcttcgaccctacagttcac
tggctgttcaccacatgcggggcaagcgggccccacggccccactcagacccagtgccac
aacgcctaccagaactccaacctgagcgtgacggtggggagcgaagggcccttgaagggc
atccagatctggaaagtgccagccaccgacacctacagcatctcatgctatggagccgct
ggcgggaaaggagggaagaacaccatgatacggtcccacggcgtgtctgtgctgggcatc
ttcaacctggagaaggacgacacgctgtacattctcgtcgggcagcagggagaggatgcc
tgccctagtaccaaccaattaatccagagagtctgtattggagagagcaatgtgatagaa
gaagaaattcgtgtgaacagaagcgtgcgtgagtgggcaggaggaggaggaggcggaggt
ggagccacttacgtgtttaagatgaaggatggggtgcccgtgcccctcattattgcagcc
ggaggtggcggcagagcctatggggccaagacagacacgttccacccggagagactggag
aataactcctctgtcctagggctgaatggcaactctggagccgcaggtggtggaggtggc
tgggatgataacacttccttgctctgggccggaaaatctttgttggagggtgctaccgga
ggacatgcctgcccccaggccatgaagaagtgggggtgggagacaagagggggtttcgga
gggggtggcggggggtgctcctcaggtggaggaggcggaggatatataggtggcaatgca
gcctcaaacaatgaccccgaaatggatggggaagatggggtttccttcatcagtcccctg
ggcgtcctgtacacaccggctttaaaagtgatggagggccacggggaagtgaacattaag
cattacctaaactgcagtcactgtgaggtagacgaatgtcatttggaccctgagagccac
aaggtcatctgcttctgtgaccatggcacagtgctggctgaggatggcgtctcctgcatt
gtgtcacccaccccagaaccccacttgcctctctcgctgatcctctccgtggtgacctct
gccctggtggccgcccttgtcctggctttctcaggcatcatgatagtgtaccgccggaag
caccaggagctgcaagccatgcagatggagctgcagagccctgagtacaagctgagcaag
ctccgcacctccaccatcatgaccgactacaaccccaattactgttttgccggcaagacc
tcctccatcagtgacctaaaagaggtgcctcggaaaaacatcaccctcattcggggtctg
ggccacggcgcatttggggaggtgtacgaaggccaggtgtccggaatgcccaacgacccg
agccccctgcaagtggctgtgaagacgctgccggaagtgtgctcagagcaggacgaacta
gacttcctcatggaagccctgatcatcagcaaattcaaccaccagaacatcgtgcgctgt
atcggggtgagcctgcaagccctgccccgcttcatcctgctagagctcatggcgggcgga
gacctcaagtccttcctccgggagacgcgccctcggccaagtcagccctcctccctggcc
atgctggaccttctgcatgtggctcgggacattgcctgtggctgtcagtatctagaggaa
aaccacttcatccaccgggacattgctgccaggaactgcctcttgacctgtcctggtagt
ggaagaatagcgaaaattggagactttggcatggcccgagacatctatagagccagctac
tacagaaagggaggctgtgctatgctgcccgtcaaatggatgcctcctgaggccttcatg
gaaggaatatttacttctaagacagacacatggtccttcggcgtgctgctgtgggaaatc
ttctctctggggtacatgccataccccagcaagagcaaccaggaggttctggagttcgta
accagtggaggacggatggacccacctaagaactgccccggacctgtataccggataatg
actcagtgctggcaacaccagcctgaagacaggcccaattttgccataattttggagagg
atcgaatactgcacacaggatccggatgtcatcaacacggccctgcccgtggagtacggc
ccgcccgtggaggaggaggagaaagtgcccgtgcggcccgaagaccctgaggggatgccg
cctctgctgctgtctcccgggcaggctccgcggggcgaggagcgcgtcccggtgcccgcg
gtgccgccgcccgcgcccgcctcgtcctccggcaaggctgtgaggaagcccgcagctacc
aggggcccggccgcgggcgggggacacgtgaacatggctttctcccaggccaacccgccg
cccgagctgcgcaggatccaggggtccagaaacaagccgaccagcttgtggaacccgact
tacggctcctggtttaccgagaaacctgccaaaaagaacagtgctccagcaaagaaggag
ccacaccagcggggcggcctgggcagcgaggggagctgcaccgtcccggccgcctccagc
gccgccggcagattgcccggcgcctccctgctgctagagccgtcctccctgccggccagc
gtgaaggaggtgccgttgttccggctgcgtcacttcccctgtgggaatgtcaactacggc
taccagcagcagggcctgcctctggaggtcaccaccgccccgggagctggacactacgag
gacgccattctgaagaacaagagcaacgccagccagcccgggccctga
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integrated database retrieval system
