Heterocephalus glaber (naked mole-rat): 101708954
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Entry
101708954 CDS
T02812
Symbol
Ryr1
Name
(RefSeq) ryanodine receptor 1
KO
K04961
ryanodine receptor 1
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04020
Calcium signaling pathway
hgl04371
Apelin signaling pathway
hgl04713
Circadian entrainment
hgl04730
Long-term depression
hgl04921
Oxytocin signaling pathway
hgl05017
Spinocerebellar ataxia
hgl05020
Prion disease
hgl05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
101708954 (Ryr1)
04020 Calcium signaling pathway
101708954 (Ryr1)
09150 Organismal Systems
09152 Endocrine system
04921 Oxytocin signaling pathway
101708954 (Ryr1)
09156 Nervous system
04730 Long-term depression
101708954 (Ryr1)
09159 Environmental adaptation
04713 Circadian entrainment
101708954 (Ryr1)
09160 Human Diseases
09164 Neurodegenerative disease
05017 Spinocerebellar ataxia
101708954 (Ryr1)
05020 Prion disease
101708954 (Ryr1)
05022 Pathways of neurodegeneration - multiple diseases
101708954 (Ryr1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hgl01009
]
101708954 (Ryr1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hgl04147
]
101708954 (Ryr1)
04040 Ion channels [BR:
hgl04040
]
101708954 (Ryr1)
Protein phosphatases and associated proteins [BR:
hgl01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
101708954 (Ryr1)
Exosome [BR:
hgl04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
101708954 (Ryr1)
Ion channels [BR:
hgl04040
]
Voltage-gated cation channels
Ryanodine receptor
101708954 (Ryr1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RYDR_Jsol
RYDR_ITPR
RyR
RR_TM4-6
SPRY
Ins145_P3_rec
MIR
RIH_assoc
Ion_trans
EF-hand_7
DNA_pol_phi
Motif
Other DBs
NCBI-GeneID:
101708954
NCBI-ProteinID:
XP_004859110
UniProt:
A0AAX6PUX3
LinkDB
All DBs
Position
Un
AA seq
5039 aa
AA seq
DB search
MGDGGEGEDEVQFLRTDDEVILQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPP
DLAICCFILEQSLSVRALQEMLANTVEAGVESSQGGGHRTLLYGHAILLRHAHSGMYLSC
LTTSRSMTDKLAFDVGLQEDATGEACWWTTHPASKQRSEGEKVRVGDDLILVSVSSERYL
HLSTASGELQVDASFMQTLWNMNPICSCCEEGYVTGGHVLRLFHGHMDECMTISPADSDD
QRRLVYYEGGSVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLALTEDQGLV
VVDASKAHTKATSFCFRISKEKLDVAPKRDVEGMGPPEIKYGESLCFVQHMASGLWLTYA
APDPKALRLGVLKKKAMLHQEGHMDDALSLTRCQQEESQAARMIHSTAALYNQFIKGLDS
FSGKPRGSGPPAGSALPIEGVILSLQDLIGYFEPPSEELQHEEKQSKLRSLRNRQSLFQE
EGMLTLVLNCIDRLNVYTTAAHFAEFAGEEAAESWKEIVNLLYELLASLIRGNRTNCALF
STNLDWVVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVL
DVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGTTQYG
KWYFEVMVDEVAPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLH
LWTGHVARLVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLDGLFFPV
VSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLHLEPIKEYRREGSRGPHLV
GPSRCLSHTDFVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDN
KRLHPCLVDFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLPKTYM
MSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVGQGWSYSAVQDIPARRNPR
LVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSQVESQSRWDRVRIFRAEKS
YVVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADDLAYVFNGHRGQRWHLGSEPFG
RPWQPGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIGDGFLPVCSLGPGQVG
HLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPLDHPHYEVSRM
DGTVDTPPCLRLTHRTWGSQNSLVEMLFLRLSLPVQFYQHFRCTAGATPLAPPGLQPPAE
DEARAAEPDPDYENLRRSAGGWGEAEGGKEGTAKEGPPGGTSPAGVEAQPARAENEKDAT
TEKNKKRGFLFKAKKAAMMTQPPATPTLPRLPRDVVPTDNRDDPEIILNTTTYYYSMRVF
AGQEPSCVWVGWVTPDYHQHDMNFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGDF
VSPGQQGRISHMDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTNQN
VIQFELGKQKNIMPLSAAMFMSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVDTRRA
GERLGWAVQCQEPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLSLYRAVCALGNNR
VAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTS
ETRAITLFPPCHSSEDGSRHHGLPGVGVTTSLRPPHHFSPPCFVMALPLSGAAEAPARLS
PAIPLEALRDKALRMLGEAVRDGGQQARDPVGGSVEFQFVPVLKLVSTLLVMGVFSNEDV
KQILKMIEPEVFKEEEEEEEEEGEEEEEEDQEEKEEDEEEGAQEKEDEEKEEEEAVEEEK
EDLEEGLLQMKLPESVKLQMCHLLEYFCDQDLQHRVESLAAFAERYVDKLQSNQRDRYGL
LMKAFTMTAAETARRTREFRSPPQEQINMLLQFKDSADEEDCPLPEDIQQDLQDFHQDLL
AHCGIQLEGEEEEPEEETTLGSRLMSLLEKVRLVKKKEEKPEEELPAEEPKPQSLQELVS
HMVVRWAQEDFVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISVSSVEDTMSLLECL
GQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGE
SKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAAS
VIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPGGGERYLDFLRFAV
FVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPARDGPGVRR
DRRREHFGEEAHEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRS
LVPLDDLVGIISLPLQIPTLGKDGALIQPKMSASFVPDHKASMVLFLDRVYGIENQDFLL
HVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMV
DSMLHTIYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKM
PLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRMA
MPCLCAIAGALPPDYVDASYSSKAEKKATVDAEGNFDPRPVETLNVIIPEKLDSFINKFA
EYTHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAW
EWTIEKAREGEEEKTEKKKTRKISQSAQTYDPREGYNPQPPDLSGVTLSRELQAMAEQLA
ENYHNTWGRKKKQELEAKGGGSHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTR
GLKDMELDTSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSGRVEKSPHEQEIKFFA
KILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGT
DAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQAR
PQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTR
NPYVEKLRPALGECLARLAAAMPVAFLEPQLNEYNACSVYTTKSPRERAILGLPNSVEEM
CPDIPVLEQLMADIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAG
APPPCTAVTSDHLNSLLGNILRIIVNNLGIDEALWMKRLAVFAQPIVSRARPELLHSHFI
PTIGRLRKRAGKVVAEEEQLRLEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNN
RAHWLTEPNPNAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADNKSKMA
KAGDVQSGGSDQERTKKKRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQELITLAKAR
YALKDTDEEVREFLQNNLNLQGKVEGSPSLRWQMALYWGVPGREEDADDPEKIVRRVQEV
SAVLYHLDQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKA
AWLLSEDHSFEDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDED
YLYIAYADIMAKSCHLEEGGENGEAQEEEGEVSFEEKEMEKQKLLYQQSRLHNRGAAEMV
LQMISACKGETGTMVSSTLKLGISILNGGNADVQQKMLDYLKDKKEVGFFQSIQALMQTC
SVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDF
QNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAK
QVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDL
QKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQD
YVTDPRGLISKKDFQKAMDSQKQFSGPEIQFLLSCSEADENEMINCEEFANRFQEPARDI
GFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISE
TNRAQWEMPQVKESKRQFIFDVVNEGGESEKMELFVSFCEDTIFEMQIAAQISEPEGEPE
EDEDEGAAEAGAEAVEEGAGVAEGAASTAAAGAKARLAAAAARALRGLSYRSLRRRVRQL
RKLTARGAATAVVTLIWAVLACAGAAGVGAAVGALRLLWGSLFGGGLVDSAKKVTVTELL
AGMPDPTGDEVHGEQPVGPGGDAGGEGTGEGEGEAAEGAGDEEVASDEAGTGRAEGAVAV
AEGSPFRPEGAGGLGDMGDTTPVEPPTPEGSPILKRKLGVDGEEEALPPDPEPEPEPKPE
KADAENGEKEEVPEPPPEPPKKTAPPPPPPKKEEAGGTGLEFWGELEVQRVKFLNYLSRN
FYTLRFLALFLAFAINFILLFYKVSDSPPGEDDMESSAAGDISGAGSGGGSGWGSGAGEE
AEGDEDENMVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELA
RKLEFDGLYITEQPEDDDVKGQWDRLVLNTPSFPRNYWDKFVKRKVLDKHGDIFGRERIA
ELLGMDLATLEITAHNERKPNPPPGLLTWLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVM
SLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNF
FRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDI
TFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETH
TLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS
NT seq
15120 nt
NT seq
+upstream
nt +downstream
nt
atgggtgacggaggagagggagaggatgaggtccagttcctccggacggacgatgaggtg
atcctgcaatgcagcgccaccgtactcaaggagcagctcaagctctgcctcgcagctgag
ggcttcggcaaccgcctctgcttcctggagcctaccagcaacgcgcagaatgtgcccccc
gacctggccatctgctgctttatcctggagcagtccctgtcagtccgagccctgcaggag
atgctggccaacacagtggaggccggtgtggagtcatcccagggcgggggacacaggaca
ctcctgtatggccatgccatcctactccgacatgcacacagcggcatgtatctgagttgt
ctcaccacctcccgctccatgactgacaagctggccttcgatgtgggactgcaggaggat
gcgacaggagaagcttgttggtggacaacacacccggcctctaagcagaggtctgaagga
gagaaggtccgtgttggagatgacctcatccttgtcagtgtctcctctgagcgctacctg
cacctgtcaactgccagtggggagctccaggttgatgcttccttcatgcagacactatgg
aacatgaaccccatctgctcctgctgcgaagagggatatgtgacagggggccacgtcctc
cgcctttttcatggacacatggatgagtgtatgaccatttcacctgctgacagtgatgac
cagcgcagacttgtctactatgagggagggtctgtgtgcacccacgcccgctccctctgg
aggctggagccactgagaatcagctggagtgggagtcaccttcgctggggccagccactg
cgcatccgacatgtcactactgggcggtacctggccctcactgaggaccagggcctggtg
gtggtggatgccagcaaggcccacactaaggccacctccttctgcttccgtatctccaag
gagaagctggatgtggcccccaagcgggatgtggagggcatgggccctcctgagatcaag
tatggggagtcactgtgctttgtgcagcacatggcctcaggcctgtggctcacctatgct
gccccagatcccaaggccctgaggcttggtgtactcaaaaagaaggccatgctgcaccag
gaaggccacatggatgacgcgctgtcactgacccgctgtcagcaggaggagtcccaggct
gcccgcatgatccacagcacagccgccctgtacaaccagttcatcaaaggcctggatagc
ttcagtgggaagccgcggggctcgggaccaccagctggctcggcgctgcccatcgaaggc
gtcatcctgagcctgcaggacctcattggctacttcgagccgccctctgaggagctacag
cacgaggagaagcagagcaagctgcgaagtctgcgcaaccgccagagcctcttccaggag
gaggggatgctcaccctggtcctgaattgcattgaccgcctaaatgtctacaccaccgct
gcccactttgccgaatttgcaggagaggaggcagctgagtcctggaaggagattgtgaac
ctgctctatgaactcctggcctctcttatccgtggcaatcgtaccaactgtgccctcttc
tccacaaatctggactgggtggtcagcaagctggatcggttggaggcctcatctggcatc
ctagaggtgctgtactgtgtcctgattgagagtcctgaggtcctgaacatcatccaggag
aaccacatcaaatccatcatctctcttctggacaagcatgggaggaaccacaaggtcctg
gacgtgctgtgctccctgtgtgtgtgcaatggtgtggctgtgcgctccaaccaagatctc
atcactgaaaacttgctccctggccgcgagcttctgctgcagacaaatctcatcaactat
gtcaccagtatccgccccaacatctttgtgggccgagcagagggcaccacacagtacggc
aaatggtactttgaggtgatggtggatgaggtggctccatttctgacagcgcaggccacc
cacctacgggtgggctgggccctcactgagggctacagcccttaccctgggggtggcgag
ggctggggcggcaacggggtcggcgatgacctctactcctacggctttgatgggctgcat
ctctggacaggacatgtggcacgcctagtgacttctccaggacagcacctcctggcccct
gaagatgtagtcagctgctgcctggacctcagtgtgccatccatctccttccgcatcaat
ggctgtcctgtgcagggtgtctttgaggccttcaacctcgatgggctcttcttccctgtt
gtcagcttttcagctggcatcaaggtgcggttcctccttggtggccgccatggtgaattc
aagttcctccccccgcctggctatgccccctgccacgaggcagtgcttcctcgggagcgg
ctccatcttgaacctatcaaggagtatcgacgggaagggtcccggggaccccacctggtg
ggccccagtcgctgcctttcacacacggactttgtgccctgccctgtggacactgtccag
attgtcctgcccccgcacctggagcgcattcgggagaagctggccgagaatatccatgag
ctgtgggcgctgacgcgcatcgagcagggctggacctatggcccggttcgagatgacaac
aagagactgcacccgtgccttgtggacttccacagcctcccagagcctgagagaaactac
aacctgcagatgtccggggagacgctcaagactctgctggcactgggctgccatgtgggc
atggcagacgagaaggcggaggacaacctgaagaagacaaagcttcccaagacgtatatg
atgagcaatgggtacaagccagctcccctggacctgagccatgtgcgactgacacctgca
cagaccacattggtggatcggctggccgagaatgggcacaatgtgtgggcaagagaccgt
gtgggtcagggctggagctacagcgctgtgcaggacatccctgcacgcagaaacccccgc
ctcgtgccctaccgcctgctggatgaggccaccaagcgcagcaaccgagacagcctctgc
caggccgtgcgcaccctgctgggatatggctacaacattgagccacctgaccaggagccc
agtcaggtggagagccagtctcgctgggaccgggtgcgcatcttcagggcagagaaatcc
tatgtggtacagagtggccgctggtacttcgagtttgaggcagttaccacaggcgagatg
cgagtgggctgggcaaggcctgagctgcggcctgatgtggagctgggagctgatgatctg
gcctatgtcttcaatgggcaccgaggccagcgctggcatttgggcagtgagccattcggg
cgtccctggcagccgggtgatgtcgttggctgcatgattgatctcactgagaacaccatt
atcttcaccctcaacggcgaggtcctcatgtctgactcaggctctgagacagccttccgg
gagattgagatcggagatggtttcctacctgtctgcagcttgggaccaggccaggtgggt
cacctgaacctgggccaggatgtgagctccctgcggttctttgccatctgcggcctccag
gaaggctttgagccattcgccatcaacatgcagcggccggtcaccacctggttcagcaaa
agccttccgcaatttgagccggtgccccttgaccatccccactatgaggtgtctcgcatg
gatggcaccgtggatacacccccctgcctgcgcctcacccaccgtacctggggctcacag
aacagcctggtggagatgctctttctccggctaagccttcctgtccagttctaccagcac
ttccgctgcaccgcaggggccacacccctggcacctcctggactgcagccccccgctgag
gacgaggctcgggcagcagaacctgaccccgactatgaaaacctccgccgctcagctggg
ggttggggcgaggctgaagggggcaaggaagggactgccaaagaggggccacctgggggc
acttctccagctggggtagaggcccagcctgccagggctgagaatgagaaggatgctacc
acagagaagaacaagaagagagggtttttattcaaggccaagaaggccgccatgatgacc
caaccaccagccacccctactctgccccgactccctcgagatgtggtgcccactgacaat
cgcgatgaccctgaaatcatcctcaacacaaccacgtactattactccatgagggtcttt
gccggccaggaacccagctgtgtgtgggtgggctgggtcacccctgactaccatcagcac
gatatgaacttcgacctcagcaaggtccgggcagtgaccgtgaccatgggggacgaacag
ggcaacgtccacagcagcctcaagtgcagcaactgctacatggtgtggggtggggacttc
gtgagccccgggcagcagggccggatcagccacatggaccttgtcattggatgcctggta
gacttggccactggcttaatgacctttacagccaatggcaaagagagcaacaccttcttc
caggtggaacccaacacgaagctgtttcctgctgtcttcgtcctgcccaccaaccagaat
gtcatccagtttgaattggggaagcagaagaacatcatgccactgtccgctgctatgttc
atgagcgagcgcaagaacccagccccgcagtgcccaccgaggctggaggtgcagatgctg
atgccagtctcctggagccgcatgcccaaccacttcctgcaggtggacacgcggcgtgct
ggcgagcggctcggctgggccgtgcagtgccaggagccgctgaccatgatggcgttgcac
atccccgaggagaacaggtgcatggatatcctggagctgtctgagcgcctggacctgcag
cgtttccactcacacaccctatccctctaccgtgcagtgtgtgccctgggcaacaaccgc
gtggctcatgctctgtgcagccacgtggaccaggcacagctgctgcatgcgctggaggac
gcacacctgccgggccctctgcgtgcaggctactatgacctcctcatcagcatccacctt
gaaagtgcctgccgcagccgccgctccatgctttcggaatacatcgtgcccctcacatcc
gagactcgtgccatcacactcttcccgccttgtcacagctccgaagatggttcccgccac
catggccttccaggcgttggagtcaccacctccctgaggcccccgcaccatttctcaccc
ccctgttttgtgatggctctaccgttgtctggggcagcagaagctccagcccgcctcagc
cctgctatccctctggaggccctgagggacaaggccctgagaatgctgggtgaggctgta
cgagatggtgggcaacaagcacgagaccctgtcgggggctccgtggagttccagttcgtg
cccgtactcaagcttgtgtccaccctgctggtgatgggtgtctttagcaatgaggatgtg
aaacagatcttgaagatgattgagcctgaagtattcaaagaggaagaagaggaagaggag
gaggaaggagaggaggaagaagaagaagatcaagaggagaaggaggaggatgaggaggaa
ggggcacaagagaaggaagatgaagaaaaagaggaagaggaggcagtagaagaggagaaa
gaagacttggaggagggactgctgcagatgaagcttccagagtctgtgaagttacagatg
tgccacctgctagagtatttctgtgaccaagatctgcagcaccgcgtggagtccctggca
gcctttgcagagcgctatgtggacaagctccagagcaaccagcgggaccgctatggcctt
ctcatgaaagccttcaccatgaccgcagctgagactgctagacgcacccgggagttccgc
tccccgccgcaagaacagatcaacatgctattgcaattcaaagacagtgcagatgaggag
gactgtcccctccctgaagacatccaacaggatttgcaggactttcatcaagacttgctg
gcccattgtggaattcagctggagggggaggaggaggaaccagaggaggagaccactctg
ggcagccgactgatgagcctgttggagaaggtgcggctggtgaagaagaaggaggagaag
ccggaggaggagctgcctgcagaggagcccaaacctcagtctctgcaggaactggtgtcc
cacatggtggtccgctgggcccaggaggacttcgtgcagagccccgagctggtccgggcc
atgttcagtctcctgcaccgacagtacgatgggcttggcgagctgctgcgtgccttgccg
cgggcatacaccatctcagtgtcctctgtggaggacaccatgagcctgctcgagtgcctg
ggccagatccgctcactgcttattgtgcagatgggcccccaggaggagaacctcatgatc
cagagcatcgggaacatcatgaacaacaaagtcttctaccaacaccccaacctaatgagg
gcactgggcatgcatgagacagtcatggaagtcatggtgaacgtccttgggggcggcgaa
tccaaggagatccgcttccccaagatggtgacgagctgctgccgcttcctctgctacttc
tgccggatcagccggcagaatcaacgctccatgtttgaccacctgagctacctgttggaa
aacagcggcattggcctgggcatgcagggctccacacccctggacgtggccgctgcctct
gtcatcgacaacaatgagctggccttggcgctgcaggagcaggacctggagaaggtcgtg
tcctatctggcaggctgtggcctccaaagctgccccatgctgctggccaaagggtaccct
gacataggctggaaccccggtggcggtgagcgctacctggatttccttcgctttgctgtc
ttcgtcaatggtgagagcgtggaggagaatgccaacgtggtggtgcggctgctcatccga
aagcccgagtgcttcgggccagcccttcggggtgagggaggctcagggctgctagctgcc
attgaagaggccatccgaatctctgaggaccctgcaagggacggcccaggtgtccgcagg
gacaggcggcgtgagcactttggtgaggaggcccatgaggaaaaccgggtgcacttggga
cacgccatcatgtccttctatgcggccttgatcgacctgctgggacgctgtgctccagag
atgcatctaatccaagccggcaagggtgaggccctgcggatccgggccatccttcgatcc
ctcgtgcccctggatgaccttgtgggcatcatcagtctcccgctgcaaatccccaccctg
ggcaaagatggggccctgatacagccaaaaatgtcagcctctttcgtgccggaccacaag
gcatccatggtgctcttcctggaccgtgtctatggcattgagaaccaggacttcctgtta
cacgtgctggatgtgggcttccttcctgacatgagggcagcagcctcgctggacacagcc
actttcagtaccacagagatggcgctggcgctgaaccgctacctttgcctggcggtgctg
ccgctcatcaccaagtgtgcaccactctttgcgggaaccgagcaccgcgccatcatggtg
gactccatgcttcacaccatttaccgcctgtcccgcggccgctcactcactaaggcgcag
cgtgatgtcatcgaggactgcctcatggcgctgtgcaggtacatccgcccatccatgctc
cagcacctgctgcggcgcctggtgttcgacgtgcccatcctgaacgagttcgccaagatg
ccgctcaagctcctcaccaaccattatgagcgctgctggaagtactactgcctccccact
ggctgggccaactttggggtcacctcggaagaagagctgcacctcacacgcaaactcttc
tggggcatctttgactccctggcacataagaaatatgaccaggagctgtaccgcatggcc
atgccctgcctgtgcgccatcgcaggggccctgcctcctgactatgtggatgcttcatac
tcttccaaggcagagaagaaggccacagtggacgctgaaggcaactttgatccccgacct
gtggagacactcaacgtaatcatcccagagaagctcgactccttcattaacaagtttgcg
gagtacacacatgagaagtgggccttcgacaagatccagaacaactggtcctatggagag
aacatagacgaggaattgaagactcaccccatgctgaggccatacaagaccttttcagaa
aaggacaaggagatttaccgctggcccatcaaggagtccttgaaggccatgattgcttgg
gaatggaccatagagaaggccagggagggtgaggaggagaagacggaaaagaagaagaca
cggaagatatcccaatctgcccagacctacgatcctcgagaaggctacaacccccagccc
cccgacctcagcggagttaccctgtcccgggagcttcaggccatggcggaacaactggca
gaaaattaccacaacacgtgggggcggaagaagaagcaagagctggaggccaagggcggt
gggtctcatcccctgctggtcccctacgacacgctcacggctaaggagaaggcacgagat
cgggagaaggcccaggagctgctcaagttcctacagatgaacggctacgcggtcaccaga
ggccttaaggacatggaactggacacgtcttccattgagaagcggtttgcttttggtttc
ctgcagcagctgctgcgctggatggacatttcccaggagttcattgcccacctcgaggct
gtggtcagcagtggacgcgtggaaaaatccccacatgaacaggagattaaattctttgcc
aagatcctgctccctttgatcaaccagtacttcaccaaccactgcctctatttcctgtcc
acaccagccaaagtgctgggcagtggtggccacgcctccaacaaggagaaggaaatgatc
accagcctcttctgcaaacttgccgctcttgtccgacaccgagtctctctcttcgggact
gatgccccagctgtggtcaactgtctccacatcttggcacgctccctggatgccaggact
gtgatgaagtcagggcctgagattgtgaaggctggcctccgctccttctttgagagcgcc
tcagaggacatcgagaagatggtagagaacctgcggctaggcaaggtgtctcaggcgcgc
ccgcaggtgaaaggcgtgggccagaacctcacttacaccacggtggccctgttgcctgtc
cttaccaccctcttccagcacatcgcccagcaccagttcggggacgacgtcatcctggat
gatgtccaggtctcttgctaccgaacgctgtgcagtatctactctctgggaaccaccagg
aacccctacgtggaaaagctgcggccagccctcggcgagtgcctggcccggctggcagca
gccatgccggtggcgttcctggagccacagctgaatgagtacaatgcatgctctgtctac
accaccaagtctccccgggagcgggccatcctggggctccccaacagcgtggaggaaatg
tgtcctgacatcccagtgctggagcagctcatggcagatattgggggcctggctgagtca
ggggcccgctacacagagatgccacacgtcattgagatcacactgcccatgctgtgcagc
tacctgccccgctggtgggagcgcgggcccgaggcgcccccacctgccctgcctgctggt
gcccccccgccctgcacagctgtcacctctgaccacctcaactccttgctggggaatatc
ctgcgcatcattgtcaacaacctgggcattgatgaggccttgtggatgaagcggcttgct
gtgtttgcccagcccattgtgagccgtgcgaggcctgagctcctgcactcccacttcatc
cctaccatcgggcggctgcgcaagcgggctgggaaagtggtggctgaggaggagcagctg
cgtctggaggccaaggcggaagccgaggagggtgagcttctggtgcgagatgagttctcc
gtgctctgccgggacctgtacgccctctacccactgctcatccgatacgtggacaacaac
agggcacactggctgacggaacccaaccccaacgccgaggagctgttcaggatggtgggg
gagatcttcatctactggtccaagtcccacaatttcaaacgtgaggagcagaacttcgtg
gtccagaacgagatcaacaacatgtcctttctgactgctgacaacaagagcaaaatggcc
aaggcgggagacgtacagtcaggtggctcagaccaggaacgcaccaagaagaagcgccgg
ggggaccggtactctgtgcagacgtccctgatcgtggccacactcaagaagatgctgccc
atcggtctgaacatgtgtgctcccactgaccaggagctcatcacactggccaaggcccgc
tatgccctgaaagacacagatgaggaggtccgggaatttctgcagaacaaccttaacctt
cagggaaaggtcgagggctcgccatccctgcgctggcagatggctctgtactggggcgtc
ccgggccgcgaggaggatgccgacgaccccgagaaaattgtgcgcagagtccaggaagta
tcggcagtgctctaccacctggaccagaccgagcacccttacaagtccaagaaggccgtg
tggcacaagctcttgtccaagcagcgtcggcgggcggtcgtggcttgtttccgcatgacg
cctctatacaacctgcccacacaccgggcatgtaacatgttcctagaaagctacaaggct
gcctggctcctgagtgaggaccacagttttgaggatcgcatgatagatgacctttcaaaa
gctggggagcaagaggaggaggaggaggaagtggaagagaagaagccagatccccttcac
cagctggtcctgcactttagccgtactgccctgactgaaaaaagcaaactagatgaggat
tacctgtacatagcatatgcggatatcatggcaaagagctgccacctggaggagggtgga
gagaatggggaagctcaagaagaggagggtgaggtgtccttcgaggagaaggagatggag
aagcagaagctgctctaccagcagtcgcggctgcacaaccggggagctgctgagatggtg
ctccagatgatcagtgcctgcaagggagagactggcaccatggtgtcctccaccctgaag
ttgggcatctccatcctcaatggaggcaatgctgacgtgcagcagaaaatgctggattat
ctgaaggacaagaaggaagtgggtttcttccagagcatccaggcgctgatgcaaacatgc
agcgtcctggatctcaatgccttcgagagacagaacaaggcagaggggctgggcatggtg
aacgaggacggcaccgtcatcaatcgccagaacggagagaaggtcatggcagatgatgaa
tttacacaagacctgttccgattcctgcaattgctgtgtgagggacacaataatgatttc
caaaactatctaaggacacagacagggaacacgaccactattaacatcatcatctgcaca
gtggactacctcctacggctgcaggaatccatcagcgacttctactggtactactcgggc
aaggacgtcattgaggagcaaggcaagaggaacttctccaaggccatgtcggtggctaag
caagtgttcaacagcctcactgagtacatacagggcccctgcaccgggaaccagcagagc
ctggcgcacagccgcctctgggacgccgtcgtgggattcctgcatgtgtttgcccacatg
atgatgaagcttgctcaggactcaagccagatcgagctgttgaaggagctgctggatctg
cagaaggacatggtggtgatgctgctgtcgttactagaagggaacgtggtgaatggcatg
attgcccggcagatggtggacatgctcgtggaatcctcatccaacgtggaaatgatcctc
aagttcttcgacatgttcctgaagctcaaggacattgtgggctccgaggccttccaggac
tatgtcaccgacccccgtggcctcatctccaagaaagacttccagaaggccatggacagc
cagaagcagttcagtggaccagagattcagttcctgctttcgtgctccgaagcggatgag
aacgagatgatcaactgtgaggagtttgccaatcgtttccaggagccagcccgcgacatc
ggcttcaacgtggcggtgctgctaactaacctgtcagagcacgtgccgcacgatccgcgc
ctgcgcaacttcctggagctggcggagagcatccttgagtacttccggccctacctgggg
cgcatcgagatcatgggtgcctcgcgccgcattgagcgcatctacttcgagatctcagaa
accaaccgcgcgcagtgggagatgccccaggtgaaggagtccaagcgccagttcatcttc
gacgtggtgaacgagggcggcgagtcggagaagatggagctcttcgtgagcttctgcgag
gacaccatcttcgagatgcagatcgctgcgcagatctcagagcccgagggcgagcccgag
gaggacgaggatgagggcgcggccgaggcgggcgcagaggccgtggaggagggcgcgggg
gttgcggagggcgcggcgagcacggcggcggcgggggccaaggcgcggctggcggcggcg
gcagcgcgggcgctgcgcggcctcagttaccgcagcctgcggcggcgcgtgcggcagcta
cggaagctcacggcgcgcggggcggccaccgcggtcgtcacgctgatctgggcagtgctg
gcgtgcgccggggcggcaggagtgggagcggcggtgggcgcgctgcgcctgctctggggc
tcgctcttcggcggcggcctggtggacagtgccaagaaggtgaccgtgaccgagctgttg
gcgggcatgcccgaccccaccggcgacgaggtgcacggcgagcagccggtggggcccggc
ggcgacgcgggcggcgagggcaccggcgaaggcgagggcgaggctgccgagggtgccggc
gacgaggaggtggcatctgacgaagctgggacgggccgcgctgagggggcggtggcggtg
gccgaggggagcccctttcggcccgaaggggctggcggccttggggacatgggtgacaca
acgccggtggagccacccacgcccgagggctccccaatactcaagaggaagctgggggtg
gatggagaagaggaggcactgcctccagatccagaacctgagcctgagcctaagccagag
aaagcagatgccgagaatggggagaaggaagaagtccctgagcccccaccagagcctccc
aagaagacagcacctcctccgccccctccaaagaaggaggaagctggagggacaggcctg
gaattctggggggaactggaagtgcagagggtgaagttcttgaactacctgtcccggaac
ttttacacgctgcgattcctggccctcttcttggcgtttgccatcaacttcatcttgctg
ttttataaggtctcagactctccaccaggggaggatgacatggagagctcggcagctggg
gacatatcgggtgcaggatctggtggcggctcaggttggggctcaggtgctggtgaggaa
gcagagggcgacgaggacgagaacatggtgtactacttcctggaggagagcaccggctat
atggagcccgcactgcggtgcctgagcctgctgcacacgctggtggcctttctgtgcatc
attggctacaactgcctcaaggtgcccctggtgatctttaagcgggaaaaggagctggcc
cgaaagctggagtttgatggcctctacatcactgagcagcctgaggatgatgatgtgaag
gggcagtgggaccgcctggtgctcaacacgccgtccttccccagaaactactgggacaag
tttgtcaagcggaaggtcctggacaaacatggggacatcttcgggcgggagcggattgca
gagctgctgggcatggatctggccaccctggagatcacagcgcacaacgagcgcaagcct
aaccctccaccagggctgctgacctggctcatgtccatagatgtcaagtaccaaatctgg
aagttcggagtcattttcacagacaattctttcctgtacctgggctggtacatggtgatg
tctctcctgggacactacaacaacttcttcttcgctgcccacctcctggacattgccatg
ggcgtcaagacgcttcgcaccatcctctcgtctgttacccacaatgggaagcagctggtg
atgaccgtgggcctcctggcggtggtggtctacctgtacactgtggtggccttcaacttc
ttccgcaagttctacaacaagagcgaagatgaggatgagccggacatgaagtgtgacgac
atgatgacgtgttacctgttccacatgtatgtgggtgtccgagccggtggaggcattggg
gatgagattgaggacccagcaggcgatgaatatgagctctaccgagtggtctttgacatc
accttcttcttctttgtcattgtcatcctgctggccatcatccagggtctgattatcgac
gcttttggtgagctccgagatcaacaagaacaagtgaaggaagatatggagaccaagtgc
ttcatctgcggcataggcagtgactattttgatacgacacctcatggatttgaaacccac
acgctagaggagcacaacctggccaattatatgttcttcctaatgtatttgataaacaaa
gatgagacagaacacacgggtcaggagtcgtatgtctggaagatgtaccaagagagatgt
tgggatttcttcccagctggtgactgtttccgcaagcagtatgaggaccagctaagctga
DBGET
integrated database retrieval system
