Heterocephalus glaber (naked mole-rat): 101713561
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Entry
101713561 CDS
T02812
Symbol
Eif2ak3
Name
(RefSeq) eukaryotic translation initiation factor 2 alpha kinase 3
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04137
Mitophagy - animal
hgl04140
Autophagy - animal
hgl04141
Protein processing in endoplasmic reticulum
hgl04210
Apoptosis
hgl04932
Non-alcoholic fatty liver disease
hgl05010
Alzheimer disease
hgl05012
Parkinson disease
hgl05014
Amyotrophic lateral sclerosis
hgl05020
Prion disease
hgl05022
Pathways of neurodegeneration - multiple diseases
hgl05160
Hepatitis C
hgl05162
Measles
hgl05168
Herpes simplex virus 1 infection
hgl05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101713561 (Eif2ak3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101713561 (Eif2ak3)
04137 Mitophagy - animal
101713561 (Eif2ak3)
09143 Cell growth and death
04210 Apoptosis
101713561 (Eif2ak3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
101713561 (Eif2ak3)
05162 Measles
101713561 (Eif2ak3)
05168 Herpes simplex virus 1 infection
101713561 (Eif2ak3)
09164 Neurodegenerative disease
05010 Alzheimer disease
101713561 (Eif2ak3)
05012 Parkinson disease
101713561 (Eif2ak3)
05014 Amyotrophic lateral sclerosis
101713561 (Eif2ak3)
05020 Prion disease
101713561 (Eif2ak3)
05022 Pathways of neurodegeneration - multiple diseases
101713561 (Eif2ak3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101713561 (Eif2ak3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101713561 (Eif2ak3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hgl01001
]
101713561 (Eif2ak3)
Enzymes [BR:
hgl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101713561 (Eif2ak3)
Protein kinases [BR:
hgl01001
]
Serine/threonine kinases: Other
PEK family [OT]
101713561 (Eif2ak3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
PQQ_2
Kdo
PQQ
ABC1
Motif
Other DBs
NCBI-GeneID:
101713561
NCBI-ProteinID:
XP_004844604
UniProt:
A0AAX6P673
LinkDB
All DBs
Position
Un
AA seq
1110 aa
AA seq
DB search
MERANRPGPLARALLMFQLLLGLATGTVAAGRARNLPAPTAEAAFGLGAAAAPTSAARRP
AAGAVAAAEVTVEDAEALPAASGEQETRGADRDDDDAELRPRGRSLVIISTLDGRIAALD
AENHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPFTVE
SLLESSYKFGDDVVLVGGKSLTTYGLSAYNGKVRYICSALGCRRWDSDEMEEEEDILLLQ
RTQKTVRAVGPRSGTEKWNFSVGHFELRYIPDMETRAGFIESTFKPSENKEESKIISDVE
EQEATMLDTVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLLRDGKVIPISLFDDT
SYGSNEEVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPTSPKALESSEN
AIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYY
LPYYKRERNKRSTQITVRFFDNPNYKSIRKKDPVLLLHWWKEIVGTILFCIIATTFIVRR
LFHPQPHRQRKESETQCQTENKYDSVRGEASDSSWNDIKSSGYVSRYLTDFEPIQCMGRG
GFGVVFEARNKVDDCNYAIKRIQLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEAP
PEKWQEKMDEIWLKDESTDWPLSSLSPMDAPSVKIRRVDPFSTKEHIEIIAPSPQRSRSF
SVGISRGQTSSSESQFSPLELSGTDHGDSSGSADAANNLQDSCLTDCDMEDGTMDANDEG
YSFELCPSEASPYVRSRETSSSIVFEDSGCDNASSKEEPKTNRVHIGNHCANKLTALKYS
SSRSSEATLSVSPPRPTTLSLDLTKNTTEKLQPSSPKVYLYIQMQLCRKENLKDWMNQRC
TLEERERGVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTVDDVVKVGDFGLVTAMDQ
DEEEQTVLTPMPATHTGQVGTKLYMSPEQIQGNNYSHKVDIFSLGLILFELLYPFSTQME
RVRTLTDVRNLKFPPLFTQKYPREYVMVQDMLSPSPVDRPEATNIIENALFEDLELPGKA
VLRQRSRSLSSSGAKHSRLPSTSGSPAPSS
NT seq
3333 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccaaccgcccggggccgctggcgcgggcgctgctgatgttccagctgctg
ctgggactcgcgacgggaacggtggccgcggggcgcgcccgaaacctcccagccccgact
gcagaggcggcgttcggcctgggggctgccgccgcccccacttcggccgcgcgaaggccg
gcggctggggcggtggccgcggctgaagtgacggtggaggacgccgaggcgctgccggcg
gcgtcgggcgagcaggagacccggggagcggaccgcgacgacgacgacgccgagctgcgg
ccgcgcggccgatcattagtaattatcagcactttagatggacgaattgctgccttggat
gctgagaatcatggtaaaaagcagtgggacttggacgtgggatctggttccttggtttca
tccagccttagcaagccagaggtatttgggaataagatgattattccttccctggatgga
gacctcttccagtgggaccgagaccgggagagcatggaaaccgttcctttcactgttgaa
tcccttcttgaatcttcttataaatttggagatgatgttgttttagttggaggaaaatct
ctcactacatatggactcagtgcgtacaatggaaaggtgaggtacatctgctctgccttg
ggttgtcgccggtgggacagcgatgagatggaagaggaagaggacatcctgcttctgcag
cgcacgcagaagactgtcagagccgtcgggcctcggagtggcactgagaagtggaatttc
agtgttggccactttgaacttcggtatattccagacatggaaactagagctggatttatt
gaaagcacctttaagcccagtgaaaacaaagaagaatctaaaattatttcagatgtggaa
gaacaggaagctaccatgctggatacagtcataaaagtctcagtcgctgattggaaggtt
atggcattcagtaagaagggaggacatctggaatgggaataccagttttgtactccaatt
gcatctgcctggttgcttagggatggaaaggtcatccccatcagtctttttgatgacaca
agttatggatctaatgaggaagttttggaagatgaagaagacattgtagaagctgcccga
ggagcaacagagaacagcgtgtacttgggaatgtatagaggccagctgtatctgcagtca
tcagtcagaatttcagaaaagtttcctacaagccccaaggccttggaatctagtgaaaat
gcaattattcctttgccaaccatcaaatggaagcccttaattcattctccttccagaact
ccagtcttggtagggtctgatgaatttgacaaatgtcttagtaatgataagttttctcat
gaagaatacagtaatggggcactttcgatcttacagtatccatatgataacggttattat
ctaccatactacaagagggaaaggaacaaacggagcacacagatcacagtcagattcttt
gacaacccaaattacaagagtatccgcaaaaaggatccagttctcctcttacattggtgg
aaagaaatagttggaaccattttgttttgtatcattgcaacaactttcattgtgcgcaga
ctttttcatcctcagcctcacagacaaaggaaggaatctgaaactcagtgtcaaactgaa
aataaatatgattctgtaagaggtgaagccagtgacagtagctggaatgacatcaaaagc
tctggatatgtctcacgatacctaacagattttgaaccaattcagtgcatgggtcgtggt
ggctttggagttgtctttgaagctagaaacaaagtagatgactgcaattatgctatcaag
aggatccagctgcccaacagagaattggctcgggaaaaggtcatgcgagaagttaaagcc
ttagccaaacttgaacacccaggaattgtgagatatttcaatgcctggctggaagcacca
ccagagaagtggcaagaaaagatggacgaaatttggctgaaagatgaaagcacagactgg
cctctcagctctcttagccccatggatgcaccatccgttaaaatacgcagggtggatcca
ttctccaccaaagaacatattgaaatcatagctccttcgccacagagaagcaggtctttt
tctgtggggatttcccgtggccagacaagctcctctgagagccagttctctcctctggag
ctgtcaggaacagaccatggagacagcagtgggtcagcggatgcagcaaacaacctgcag
gacagttgcctcacagactgtgacatggaagatggcactatggacgccaatgatgagggt
tactcctttgaactttgtccttctgaagcttctccctacgtgaggtcaagggagacctcc
tcttccatagtgtttgaagattctggctgtgataatgcatccagtaaagaagagcccaaa
actaaccgagtgcatattggcaaccattgtgctaataaactcactgccttgaagtactcc
agcagcagatcttcagaagccaccttgtctgtttctccgccaagaccaaccactttaagt
ttagatctcactaagaacactacagagaaactccagcccagctcaccaaaggtgtatctt
tacattcaaatgcagctgtgcagaaaagaaaacctcaaagactggatgaaccagcggtgt
acgctggaggagcgggagcggggcgtgtgtctgcacatcttcctgcagatcgctgaggcg
gtggagttcctgcacagcaaagggctcatgcacagggacctcaagccttccaatatattc
ttcacagtggacgacgtggtcaaggttggagactttgggctagtgaccgccatggaccag
gatgaggaggagcagacagttctgacccccatgccagccacacacacaggacaagtgggg
accaaactgtacatgagcccagagcagatccaaggaaacaactactctcataaagtggac
atcttttccttaggcctgattctatttgaactgctgtacccattcagcactcagatggaa
agagtccggaccttgactgatgtaagaaatctcaaatttccaccactgttcactcagaaa
tatcctcgtgagtatgtgatggttcaagacatgctctctccctcccccgtggatcgacct
gaagccacgaacatcattgaaaatgctctgtttgaggacttggagttgccagggaaagcg
gtgctcagacagcggtctcgctccctgagctcgtcaggcgcgaagcactcgagactgccc
agcacctccggcagccctgcgcccagcagttag
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