Heterocephalus glaber (naked mole-rat): 101717035
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Entry
101717035 CDS
T02812
Symbol
Grb2
Name
(RefSeq) growth factor receptor bound protein 2
KO
K04364
growth factor receptor-bound protein 2
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl01521
EGFR tyrosine kinase inhibitor resistance
hgl01522
Endocrine resistance
hgl04010
MAPK signaling pathway
hgl04012
ErbB signaling pathway
hgl04014
Ras signaling pathway
hgl04062
Chemokine signaling pathway
hgl04068
FoxO signaling pathway
hgl04072
Phospholipase D signaling pathway
hgl04150
mTOR signaling pathway
hgl04151
PI3K-Akt signaling pathway
hgl04380
Osteoclast differentiation
hgl04510
Focal adhesion
hgl04540
Gap junction
hgl04550
Signaling pathways regulating pluripotency of stem cells
hgl04630
JAK-STAT signaling pathway
hgl04650
Natural killer cell mediated cytotoxicity
hgl04660
T cell receptor signaling pathway
hgl04662
B cell receptor signaling pathway
hgl04664
Fc epsilon RI signaling pathway
hgl04714
Thermogenesis
hgl04722
Neurotrophin signaling pathway
hgl04910
Insulin signaling pathway
hgl04912
GnRH signaling pathway
hgl04915
Estrogen signaling pathway
hgl04917
Prolactin signaling pathway
hgl04926
Relaxin signaling pathway
hgl04935
Growth hormone synthesis, secretion and action
hgl05034
Alcoholism
hgl05160
Hepatitis C
hgl05161
Hepatitis B
hgl05163
Human cytomegalovirus infection
hgl05165
Human papillomavirus infection
hgl05200
Pathways in cancer
hgl05203
Viral carcinogenesis
hgl05205
Proteoglycans in cancer
hgl05206
MicroRNAs in cancer
hgl05207
Chemical carcinogenesis - receptor activation
hgl05208
Chemical carcinogenesis - reactive oxygen species
hgl05210
Colorectal cancer
hgl05211
Renal cell carcinoma
hgl05213
Endometrial cancer
hgl05214
Glioma
hgl05215
Prostate cancer
hgl05220
Chronic myeloid leukemia
hgl05221
Acute myeloid leukemia
hgl05223
Non-small cell lung cancer
hgl05224
Breast cancer
hgl05225
Hepatocellular carcinoma
hgl05226
Gastric cancer
hgl05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101717035 (Grb2)
04012 ErbB signaling pathway
101717035 (Grb2)
04014 Ras signaling pathway
101717035 (Grb2)
04630 JAK-STAT signaling pathway
101717035 (Grb2)
04068 FoxO signaling pathway
101717035 (Grb2)
04072 Phospholipase D signaling pathway
101717035 (Grb2)
04151 PI3K-Akt signaling pathway
101717035 (Grb2)
04150 mTOR signaling pathway
101717035 (Grb2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101717035 (Grb2)
04540 Gap junction
101717035 (Grb2)
04550 Signaling pathways regulating pluripotency of stem cells
101717035 (Grb2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
101717035 (Grb2)
04660 T cell receptor signaling pathway
101717035 (Grb2)
04662 B cell receptor signaling pathway
101717035 (Grb2)
04664 Fc epsilon RI signaling pathway
101717035 (Grb2)
04062 Chemokine signaling pathway
101717035 (Grb2)
09152 Endocrine system
04910 Insulin signaling pathway
101717035 (Grb2)
04912 GnRH signaling pathway
101717035 (Grb2)
04915 Estrogen signaling pathway
101717035 (Grb2)
04917 Prolactin signaling pathway
101717035 (Grb2)
04926 Relaxin signaling pathway
101717035 (Grb2)
04935 Growth hormone synthesis, secretion and action
101717035 (Grb2)
09156 Nervous system
04722 Neurotrophin signaling pathway
101717035 (Grb2)
09158 Development and regeneration
04380 Osteoclast differentiation
101717035 (Grb2)
09159 Environmental adaptation
04714 Thermogenesis
101717035 (Grb2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101717035 (Grb2)
05206 MicroRNAs in cancer
101717035 (Grb2)
05205 Proteoglycans in cancer
101717035 (Grb2)
05207 Chemical carcinogenesis - receptor activation
101717035 (Grb2)
05208 Chemical carcinogenesis - reactive oxygen species
101717035 (Grb2)
05203 Viral carcinogenesis
101717035 (Grb2)
05231 Choline metabolism in cancer
101717035 (Grb2)
09162 Cancer: specific types
05210 Colorectal cancer
101717035 (Grb2)
05225 Hepatocellular carcinoma
101717035 (Grb2)
05226 Gastric cancer
101717035 (Grb2)
05214 Glioma
101717035 (Grb2)
05221 Acute myeloid leukemia
101717035 (Grb2)
05220 Chronic myeloid leukemia
101717035 (Grb2)
05211 Renal cell carcinoma
101717035 (Grb2)
05215 Prostate cancer
101717035 (Grb2)
05213 Endometrial cancer
101717035 (Grb2)
05224 Breast cancer
101717035 (Grb2)
05223 Non-small cell lung cancer
101717035 (Grb2)
09172 Infectious disease: viral
05161 Hepatitis B
101717035 (Grb2)
05160 Hepatitis C
101717035 (Grb2)
05163 Human cytomegalovirus infection
101717035 (Grb2)
05165 Human papillomavirus infection
101717035 (Grb2)
09165 Substance dependence
05034 Alcoholism
101717035 (Grb2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101717035 (Grb2)
01522 Endocrine resistance
101717035 (Grb2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hgl04131
]
101717035 (Grb2)
Membrane trafficking [BR:
hgl04131
]
Endocytosis
Clathrin-mediated endocytosis
Receptor tyrosine kinase (RTK) adaptor proteins
101717035 (Grb2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SH3_1
SH3_9
SH3_2
SH2
SH3_10
SH3_3
DUF7145
SH2_2
DUF5093
hSH3
SH3_4
DUF7063
Motif
Other DBs
NCBI-GeneID:
101717035
NCBI-ProteinID:
XP_004860721
UniProt:
G5BNB5
LinkDB
All DBs
Position
Un
AA seq
217 aa
AA seq
DB search
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq
654 nt
NT seq
+upstream
nt +downstream
nt
atggaagccatcgccaaatatgacttcaaagctactgcggacgatgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaattggtacaaggcagag
ctcaacggcaaggatggcttcatccccaagaactacatagagatgaagccacacccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcatgat
ggggcctttctaatccgggaaagtgagagcgctcctggggatttctccctctccgtcaag
tttggaaatgatgtgcagcacttcaaggtgctccgtgatggagccggaaagtatttcctc
tgggtggtgaagttcaattctttgaatgagctggtagattaccacagatcgacatccgtg
tccagaaaccagcagatattcctgcgggacatagaacaagtgccacagcagccgacatat
gtccaggccctctttgactttgacccccaggaggacggagagctgggcttccgccgggga
gacttcatccacgtcatggataactcagaccccaactggtggaagggggcttgccacggg
cagaccggcatgtttccccgcaactatgtcacccctgtgaaccggaacgtctaa
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