Heterocephalus glaber (naked mole-rat): 101717565
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Entry
101717565 CDS
T02812
Symbol
Ret
Name
(RefSeq) ret proto-oncogene
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04010
MAPK signaling pathway
hgl04020
Calcium signaling pathway
hgl04151
PI3K-Akt signaling pathway
hgl05200
Pathways in cancer
hgl05216
Thyroid cancer
hgl05223
Non-small cell lung cancer
hgl05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101717565 (Ret)
04020 Calcium signaling pathway
101717565 (Ret)
04151 PI3K-Akt signaling pathway
101717565 (Ret)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101717565 (Ret)
05230 Central carbon metabolism in cancer
101717565 (Ret)
09162 Cancer: specific types
05216 Thyroid cancer
101717565 (Ret)
05223 Non-small cell lung cancer
101717565 (Ret)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hgl01001
]
101717565 (Ret)
Enzymes [BR:
hgl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101717565 (Ret)
Protein kinases [BR:
hgl01001
]
Receptor tyrosine kinases (RTK)
RET family
101717565 (Ret)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD4
RET_CLD3
RET_CLD1
Pkinase
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
ABC1
Motif
Other DBs
NCBI-GeneID:
101717565
NCBI-ProteinID:
XP_004874148
LinkDB
All DBs
Position
Un
AA seq
1140 aa
AA seq
DB search
MAKATSGAVGLWLLLLLPLLGEAPLGLYFPRDAYWERLYLDQPAHTPLLYVHALQDMPGE
VPRFHVGQHLYGVYHKPLHKNDWIRVEDTGLLYLNRSLDRDSWEQLSLRNGGFPLLTIFL
HVFLSYPPLREGECHWPGCTRVYFSFINTSFPACSSLSLREICFPENGLSFRIRENRPSG
TFHQFRLLPVHFLCPNISVAYRLLQGDGGPFRCAPDSLKVSTQRVLDREHRERFDLVATC
TMRSGAHEDEVREPFLVTVYDEDDSAPSVSGVGDTANAEVAFRRKEGTVVATLRVFDADV
VPASSELARRYTGTLLPRDPWAQEHFRLEHVPNETRVAAEGGGTVRATVHDFKLVLNQSL
PISESRALQLDVLVNDSTFQGPGSGVLLLHFNVSVLPIHLRLTSTYSFSVSRKAHRYAQV
GKVCVEHCWELSGVRVQYKLQPSGVNCSALGVLSSAKDTSGTLFVNDTEALQRPECDELQ
YTVVATDQETHAQAQAALLVTVEGTYVAEAAGCPLSCAVSKRHPDCEECGGLGALSGRCE
WRQGDGKGISRNFSTCSPSTRTCPDGHCDVVENQDPHICPQDCLRGSIVGGYEPGERRGI
RAGHGTCSCFPEEKKCFCEPEDSQAPLCDDLCRTVIAAAVLFSFIVSVLLSTFCVHRYHK
HAHKPPIASAEMTFCRPAQAFPISYSSAGARRPSLDSMENQVSVDTVKIQEDPKWEFPRK
DLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRDLMSEFNLLKQV
NHPHVIRLYGACSQDGPGCAWPPDGPTQPRTAGHCHRFSSESTRPLLLIVEYAKYGSLRG
FLRDSRKVGPGYVGNGGSRNSGTLDHPDERALTMGDLISFAWQISRGMQYLAEMKLVHRD
LAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDV
WSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMDRPDNCSEEMYRLMLQCWKQEPDK
RPTFADISKDLEKMMVKSRDYLDLAASTPSDSLLYDDGLSEEETPLVDCSSTPVPRALPS
TWIENKLYGMSDPSWPGESPVPLPRADDTNTGFPRYANDSVYANWMVSPAAAKLMDTPDS
NT seq
3423 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaggcgacgtccggcgccgtggggctgtggctcttgctgctgctgccactgctc
ggcgaagcccccctgggcctctacttcccgagggacgcctactgggagcggctgtacttg
gaccagccggcccacacaccactgctctatgtgcacgctctacaagacatgcctggggag
gtcccccgtttccacgtgggccagcacctctatggcgtctaccacaagccactgcacaag
aacgactggatccgtgtggaggacactggtcttctctacctcaaccgaagcctggaccgt
gactcctgggagcagctcagcctgcggaacggcggcttccccctgctgaccatcttcctg
catgtcttcctgtcgtacccgcccctgagagaaggcgagtgccactggccggggtgcacc
cgagtatatttctccttcatcaacacctccttccctgcctgcagctccctttcactccgg
gagatttgcttcccggagaacgggctgtccttccgcatccgtgagaacaggccgtccggc
accttccaccagttccgtctgctgcccgtgcacttcctgtgccccaacatcagtgtggcc
tacaggctcctgcagggtgacggtggccccttccgctgtgccccggacagcctgaaggtg
agcacgcagcgcgtgctggaccgggagcaccgggagcgctttgacctggtggccacatgc
accatgcgctctggcgcacatgaggacgaggtgcgggagcccttcctggtcacagtgtac
gacgaggacgactcggcgcccagcgtgtcgggggtgggggacacggccaatgccgaggtg
gctttccggcgcaaggagggcacagtggtggccacactacgcgtgttcgacgcggatgtg
gtgcctgcctcgtcggagctggcccggcgctacactggcacactgctgccgcgggatccc
tgggcgcaggagcacttccgcctggagcacgtgcccaatgagacccgcgtggccgcggag
ggtggcggcaccgtgcgcgccacagtgcacgacttcaagctggtgctcaaccagagcctg
cccatctccgagagccgagccctgcagctggatgtgctggtcaacgactccaccttccag
ggcccaggctcaggcgtcctcctcctccacttcaacgtgtcagtgctgcccatccacctg
cgcctgaccagcacctactctttctccgtgagcaggaaggcgcaccgttatgcccaggtc
ggcaaggtctgtgtggagcactgctgggaactcagcggtgtccgtgtccagtacaagctg
cagccatctggtgtcaactgcagtgccctgggggtgctcagctcagccaaggacacctca
gggaccctgttcgtgaacgacacggaagctttacagcggcctgagtgtgatgagctgcag
tacacagtggtggccaccgaccaggagacccacgctcaggcccaggctgcactgctggtc
actgtggaggggacatacgtggctgaggcagcgggctgccccctatcctgtgcagtcagc
aagaggcacccggactgtgaggagtgcggtggcctgggtgccctgtccggccggtgcgag
tggcggcagggtgatggcaaagggatctccaggaacttctccacctgctcccccagcacc
aggacctgccctgatggccactgcgatgtcgtggagaaccaggacccccacatctgcccc
caggactgcttgcggggcagcattgttggagggtatgagcctggggagcgccgggggatt
agagccggacatggtacctgtagctgctttccagaggagaagaagtgcttctgcgagccc
gaggacagccaggcccccctttgtgatgacctatgtcgcacggtgatcgcagcagctgtg
ctcttctccttcatcgtctcggtgctgctgtccactttctgtgtccaccgctaccacaag
catgcacacaagcctcccatcgcgtccgcagagatgaccttctgccgtcctgcccaggcc
ttccccatcagctactcctcagcgggagcccgccggccctcactggactccatggagaac
caggtctctgtggacaccgtcaagatccaggaggacccaaagtgggaattccctcgaaag
gacctggttctcgggaagaccctgggagagggcgagtttgggaaggtggtaaaggccacg
gccttccgcttgaagggcagagctggctacaccacagtggccgtgaagatgctgaaagag
aatgcatcccagagtgagcttcgggacctgatgtccgagttcaatctcctgaagcaggtc
aaccacccgcacgtcatcaggctatacggggcctgcagccaggatggccctgggtgtgca
tggcctccagatggcccaacccagccccgcacggcaggacactgtcaccgtttctcatcc
gagagtacacgcccgctcctcctcatcgtggagtacgccaagtatgggtccctgcggggt
ttcctccgggatagccgcaaggtagggcctggctacgtgggcaatggaggcagccgaaac
tctggcaccctggaccatccggacgagcgggcactgaccatgggcgacctgatctccttc
gcctggcagatctccagggggatgcagtacctggctgagatgaagcttgtgcaccgggac
ctggcagccaggaacatcctggtggccgaggggcgaaagatgaagatctcagacttcggg
ctgtcccgagacgtatatgaagaggactcctacgtgaagaggagcaagggccggattcct
gtcaagtggatggcaatcgagtccctgttcgaccatatctacaccacccagagtgacgtg
tggtccttcggggtcctgctgtgggagattgtgaccctggggggcaatccataccccggg
attcctcccgagcggctcttcaacctcctgaagacaggccaccgcatggacaggccggac
aactgcagtgaagagatgtaccgcctcatgctgcagtgctggaagcaggaaccagacaag
cggcccacgtttgcggacatcagcaaagacctggagaagatgatggtcaagagcagagac
tatctggatctcgcagcatctaccccatcagactcactgctgtacgacgatggtctctcg
gaggaggagacaccactggtggactgcagcagcacccccgtccctcgcgccctcccctcc
acatggattgaaaacaaactctatggcatgtcagacccgagctggcctggagagagtcct
gtaccactcccgagagccgatgacactaacactgggtttccaagatatgcaaatgatagt
gtatatgctaactggatggtttcacccgcagcggcaaagttaatggacacacctgatagt
taa
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