Heterocephalus glaber (naked mole-rat): 101723930 Help Entry 101723930         CDS       T02812                                  Symbol Shc2 Name (RefSeq) SHC adaptor protein 2   KO K17447   SHC-transforming protein 2 Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl01521   EGFR tyrosine kinase inhibitor resistance hgl01522   Endocrine resistance hgl04012   ErbB signaling pathway hgl04014   Ras signaling pathway hgl04062   Chemokine signaling pathway hgl04072   Phospholipase D signaling pathway hgl04370   VEGF signaling pathway hgl04510   Focal adhesion hgl04650   Natural killer cell mediated cytotoxicity hgl04722   Neurotrophin signaling pathway hgl04910   Insulin signaling pathway hgl04915   Estrogen signaling pathway hgl04917   Prolactin signaling pathway hgl04926   Relaxin signaling pathway hgl04935   Growth hormone synthesis, secretion and action hgl05034   Alcoholism hgl05100   Bacterial invasion of epithelial cells hgl05214   Glioma hgl05220   Chronic myeloid leukemia hgl05224   Breast cancer hgl05225   Hepatocellular carcinoma hgl05226   Gastric cancer Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     101723930 (Shc2)    04014 Ras signaling pathway     101723930 (Shc2)    04370 VEGF signaling pathway     101723930 (Shc2)    04072 Phospholipase D signaling pathway     101723930 (Shc2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     101723930 (Shc2)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     101723930 (Shc2)    04062 Chemokine signaling pathway     101723930 (Shc2)   09152 Endocrine system    04910 Insulin signaling pathway     101723930 (Shc2)    04915 Estrogen signaling pathway     101723930 (Shc2)    04917 Prolactin signaling pathway     101723930 (Shc2)    04926 Relaxin signaling pathway     101723930 (Shc2)    04935 Growth hormone synthesis, secretion and action     101723930 (Shc2)   09156 Nervous system    04722 Neurotrophin signaling pathway     101723930 (Shc2)  09160 Human Diseases   09162 Cancer: specific types    05225 Hepatocellular carcinoma     101723930 (Shc2)    05226 Gastric cancer     101723930 (Shc2)    05214 Glioma     101723930 (Shc2)    05220 Chronic myeloid leukemia     101723930 (Shc2)    05224 Breast cancer     101723930 (Shc2)   09171 Infectious disease: bacterial    05100 Bacterial invasion of epithelial cells     101723930 (Shc2)   09165 Substance dependence    05034 Alcoholism     101723930 (Shc2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101723930 (Shc2)    01522 Endocrine resistance     101723930 (Shc2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PID SH2 DUF7063 Motif Other DBs NCBI-GeneID:  101723930 NCBI-ProteinID:  XP_004866085 UniProt:  A0AAX6Q5R6 LinkDB All DBs Position Un AA seq 581 aa AA seqDB search MTQGPGGRAPPAGPEPEAPTTFCALLPRMPQWKFAAPAGFLGRGPAAGATRTAGATGAEG AAGTGDPRTEHAGPALAAVLGACEPRCAAPCPLPALSRCRASGARGPRGARGLAGPPDAL ADEWERKSGFIHKPAHGWLHPDARVLGPGVSYIVRYMGCIEVLRSMRSLDFSTRTQVTRE AINRLHEAVPGVRGSWKKKAPNKALASILGKSNLRFAGMSISVNISIDGLNLLVPATRQV IASHHMQSISFASGGDTDMTDYVAYVAKDPINQRACHILECCEGLAQSVISTVGQAFELR FKQYLHSPPKAVVPPERLTGLEESAWGDEEEVEGHNYYNSIPGKEPPPGGLVDSRLAITQ PCGLAALGQGASPFRRDARSLQWDQSSSGSAPPGDGYVQADARGPRDYEEHLYVNTQGLD APEPEDLVPPQPEESPKKDLFDMRPFEDALRLHECAAGIAEDQWPSPPTRRAPVAPTEEQ LRQEPWYHGRMSRRAAERLLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVV RTKDVLFESISHLIDYHLQNGQPIVAAESELHLRGVVAREH NT seq 1746 nt NT seq  +upstreamnt  +downstreamnt atgacgcagggtccgggcgggcgggcgccccccgcgggccccgagcccgaggcgcccacc accttctgcgcgctgctgccgcgcatgccgcagtggaagttcgcggcacccgccggcttc ttgggccgcgggccagctgcgggggcgacgcggacggctggggccacgggggccgagggc gcggcgggcacgggcgacccccggacggagcacgcaggccccgcgctggccgccgtgcta ggcgcctgcgagccgcgctgcgccgcgccctgcccgctgcctgcgctcagccgctgccgg gcctcgggggcgcgcgggccgcggggcgcgcggggtttggccgggcccccagacgccttg gccgacgagtgggagcgcaagagcggcttcatccacaagcccgcgcacggctggctgcac cccgatgccagggtgctggggcccggggtctcctacatcgtccggtacatgggctgcatt gaggtgctcagatccatgcgctccctggacttcagcactcggacccaggtgaccagggag gccatcaatcggctccacgaggccgtgccaggcgtcaggggctcctggaagaagaaggcg cccaacaaggcgctggcctctatcctgggcaaaagcaacctgcgcttcgcgggcatgagc atttccgtgaatatttctatcgatggcctcaacctcttggtgcccgccacgcgtcaggtc atcgccagccatcacatgcagtccatctcctttgcgtcgggcggtgacacggacatgacg gattacgtggcctatgtcgccaaggaccccatcaaccagagagcctgtcacatcctggag tgctgcgagggcctggcgcagagtgtcatcagcaccgtgggccaagccttcgagttgcgc ttcaagcagtacctgcacagcccccccaaggcagtcgtgcctcccgaaaggctgactggg ctggaggagtcggcctggggggacgaggaggaggtcgaaggacacaactactacaacagc atcccggggaaggagccgccgcctggcgggctggtggactccaggctggccatcacgcag ccctgcggccttgcagcccttggccagggagcatctccctttcgaagagacgcccgcagc ctgcagtgggaccagagctcttctggctcagccccgccgggggatggctatgtgcaggcg gatgctcgggggcctcgggactatgaggagcacctgtacgtcaacacgcagggtctggat gccccggagcctgaagacctggtgcctccgcagcctgaggagagccccaagaaggacctg ttcgacatgcgacccttcgaggacgccctgaggctgcatgagtgtgctgcaggcatagca gaggaccagtggcccagtcctcccacccgtcgggctcccgtcgcccccactgaagagcag ctgcggcaggaaccctggtaccatggccgcatgagccgcagggccgccgagaggctgctg cgagctgatggggacttcctggtacgagatagcgtcaccaaccccgggcagtacgtcctc acaggcatgcacgccggacagcccaagcacctgctgctggtggaccccgagggtgtggtg cgaacgaaggatgtgctgttcgagagcatcagccacctcatcgattaccacctgcagaac gggcagcccatcgtggctgctgagagcgagctgcacctgcgtggcgtggttgcgcgggag cactga

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