Heterocephalus glaber (naked mole-rat): 101724195
Help
Entry
101724195 CDS
T02812
Symbol
Rock2
Name
(RefSeq) Rho associated coiled-coil containing protein kinase 2
KO
K17388
Rho-associated protein kinase 2 [EC:
2.7.11.39
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04022
cGMP-PKG signaling pathway
hgl04024
cAMP signaling pathway
hgl04062
Chemokine signaling pathway
hgl04071
Sphingolipid signaling pathway
hgl04270
Vascular smooth muscle contraction
hgl04310
Wnt signaling pathway
hgl04360
Axon guidance
hgl04510
Focal adhesion
hgl04519
Cadherin signaling
hgl04520
Adherens junction
hgl04530
Tight junction
hgl04611
Platelet activation
hgl04670
Leukocyte transendothelial migration
hgl04810
Regulation of actin cytoskeleton
hgl04921
Oxytocin signaling pathway
hgl05132
Salmonella infection
hgl05135
Yersinia infection
hgl05163
Human cytomegalovirus infection
hgl05200
Pathways in cancer
hgl05205
Proteoglycans in cancer
hgl05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
101724195 (Rock2)
04071 Sphingolipid signaling pathway
101724195 (Rock2)
04024 cAMP signaling pathway
101724195 (Rock2)
04022 cGMP-PKG signaling pathway
101724195 (Rock2)
09133 Signaling molecules and interaction
04519 Cadherin signaling
101724195 (Rock2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101724195 (Rock2)
04520 Adherens junction
101724195 (Rock2)
04530 Tight junction
101724195 (Rock2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101724195 (Rock2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101724195 (Rock2)
04670 Leukocyte transendothelial migration
101724195 (Rock2)
04062 Chemokine signaling pathway
101724195 (Rock2)
09152 Endocrine system
04921 Oxytocin signaling pathway
101724195 (Rock2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
101724195 (Rock2)
09158 Development and regeneration
04360 Axon guidance
101724195 (Rock2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101724195 (Rock2)
05205 Proteoglycans in cancer
101724195 (Rock2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
101724195 (Rock2)
09171 Infectious disease: bacterial
05132 Salmonella infection
101724195 (Rock2)
05135 Yersinia infection
101724195 (Rock2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101724195 (Rock2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hgl01001
]
101724195 (Rock2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hgl03036
]
101724195 (Rock2)
Enzymes [BR:
hgl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
101724195 (Rock2)
Protein kinases [BR:
hgl01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
101724195 (Rock2)
Chromosome and associated proteins [BR:
hgl03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
101724195 (Rock2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH_MRCK
PH
C1_1
APH
Pkinase_C
Motif
Other DBs
NCBI-GeneID:
101724195
NCBI-ProteinID:
XP_004870001
LinkDB
All DBs
Position
Un
AA seq
1388 aa
AA seq
DB search
MSRAPPPGKMPGDPEEAGPGDGAADRRRKLDALLRDPRSPINVDSLLDGLNSLVLDLDFP
ALRKNKNIDNFLNRYEKVVKKVRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQNVYAM
KLLSKFEMIKRSDAAFFWEERDIMAFANSPWVVELFCAFQDDKYLYMVMEYMPGGDLVNL
MSNYDVPEKWAKFYTAEVVLALDVIHSMGLIHRDVKPDNMLLDRHGHLKLADFGTCMKMD
ETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLV
GTYSKIMDHKNSLSIPEDAEISKHAKNLICAFLTEREVRLGRNGVEEIKQHPFFKNDQWN
WDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRDDL
LLSDSPPCRESDSVQSRKNEESQEIQKKLYSLEERFNSELQAKEELEQKCKSINTRLEKT
AKELEEEITLRKNVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQL
EDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNR
DLQDKNCLLETARLKLEKEFINLQSALESERRDWTHRSEIISDLQGRISGLEEDLKNGKI
LLAKVELEKRQLQEKLTDLEKEKSNMEIDMTYQLKVIQQSFEQEEAEHKATKARLADKNK
IYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLESEKKCSMLDCDLKQSQQKLNELLK
QKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLVEMKLS
LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLCKELQQK
KQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
LTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDAQEQLSRLKDEELSATAVKAQF
EKQLLTERTLKTQAVNKLAEIMNRKEPIKRGSDTDVRRKEKENRKLHMELKSEREKLTQQ
MIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
DTEAEDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVL
DIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKG
HEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHLDRKEEIIAPCKVYYD
ISTAKNLLLLANSTEEQQRWVSRLVKKIPKKPPAPDPFARSSPRTSMKIPQNQSVRRPSR
QLAPNKPS
NT seq
4167 nt
NT seq
+upstream
nt +downstream
nt
atgagcagggccccgccgcccgggaagatgcctggcgaccccgaggaggccgggcccggg
gacggggccgccgaccgccgcaggaagctggacgcgctgcttcgggacccgcgctcacct
atcaacgtggacagcctgctggatggcttaaattccttggtccttgatttggattttcca
gccttgaggaaaaataagaatatagataatttcttaaatagatatgagaaagttgtgaaa
aaagtccgaggcctgcagatgaaggcggaagactatgatgttgtaaaagtcatcgggaga
ggagctttcggtgaagtgcagttggttcgtcataaggcatcacagaatgtgtatgccatg
aagctgcttagtaagtttgaaatgatcaaaagatcagatgctgcttttttctgggaagaa
agagatattatggcctttgccaatagtccctgggtggttgagctcttctgcgccttccaa
gatgataagtatctatatatggtcatggaatacatgcctggtggggaccttgtaaacctg
atgagtaactacgatgtgcctgagaagtgggccaagttctacactgcagaagtggttctg
gctctggatgtgattcactccatgggtctgatccacagggatgtcaagcctgacaacatg
ctgctggataggcatgggcacctgaagctggcagactttggcacctgtatgaagatggat
gagacaggcatggtgcactgtgacacagcggtcggaaccccagactacatatcaccagag
gttctgaaatcgcaagggggcgacggttattacgggagagagtgtgactggtggtctgtc
ggggttttcctttttgaaatgctagtgggagatactccgttttatgcagattcacttgta
ggaacttacagcaaaattatggatcataaaaattcactatctatccccgaagatgcagaa
atttctaaacatgcaaagaatctcatctgtgccttcttaacagaaagggaggtacgcctt
gggagaaatggggtagaagaaatcaaacagcatcctttctttaagaatgatcaatggaat
tgggataacataagagagacggcagctcctgtagtgcctgagctcagcagtgacatagac
agcagcaacttcgatgatattgaggatgataaaggagatgtcgaaaccttcccaattcct
aaagcttttgtgggaaatcagctgccctttataggatttacctactatagagacgatttg
ttgttaagcgactctccgccttgcagagaaagtgactcagtacaatcaaggaaaaatgaa
gaaagtcaagagattcagaaaaaactgtatagcttagaagaacgctttaacagtgagcta
caagccaaagaggagctcgagcagaagtgcaaatctatcaatactcgcctagagaaaaca
gcaaaggagctagaagaagagattaccttacggaaaaatgtggaatcagcattaagacaa
ttagaaagagaaaaggcgcttcttcagcacaaaaatgcagaatatcaaaggaaagctgat
cacgaagcagacaagaaacgaaatttagaaaatgatgtcaacagcttaaaagatcaactt
gaagatttgaaaaaaagaaaccagaactctcaaatatctaccgagaaagtgaaccagcta
cagagacagctggatgaaacgaatgctttgctgcgaacagaatctgatactgcagcccgg
ttgagaaagacccaggcggaaagttccaaacagattcaacagctggaatccaacaacaga
gatctgcaggataaaaactgcctgctagagactgccaggttaaaactggaaaaggagttt
atcaatcttcagtctgctctggagtcagaaaggagggactggacccacagatcagagatc
atcagtgacttacaaggtagaatatctggcctagaagaagatttaaagaatggcaaaatc
ttactagcaaaagtagaactggagaagagacaactgcaggagaagcttactgatttggaa
aaggaaaagagcaacatggaaatagacatgacataccagctcaaagttatccagcagagc
ttcgagcaggaagaagctgagcacaaggccacgaaagcgcggctcgcagacaaaaataag
atctacgaatccattgaggaagctaaatcggaagccatgaaagaaatggaaaagaagctg
ttggaagaaaggactttaaaacagaaggtagagaacctgctgctggagtcggagaagaag
tgctccatgctggactgcgacctgaagcagtcgcagcagaagctgaacgagctcctcaag
cagaaggacgtgctcaacgaggatgttagaaacttgacgttaaagatagagcaggaaact
cagaagcgctgcctcacacagaatgacctgaagatgcagacacagcaggtgaacacactg
aagatgtcagagaaacagctgaaacaggagaacaaccacctggtggagatgaagctgagc
ttggagaagcagaacgccgagctccgaaaagaacggcaggatgcagatgggcagatgaaa
gagctgcaagatcagcttgaagcagagcagtatttctccaccctctataaaacccaagtt
agggaacttaaagaagaatgcgaagaaaagaccaaactttgtaaagagttacagcagaag
aagcaggagctccaggatgaaagggactccttggccgcccagctggagatcaccttgacc
aaggcggactccgaacagctggctcgctcaattgctgaagaacagtattccgatttggaa
aaggagaagatcatgaaagagctggagatcaaggagatgatggccagacataaacaggag
ctcactgagaaggacgccaccattgcctcgcttgaagaaacaaacaggacactaactagt
gatgttgccaatcttgccaacgagaaagaagaattaaataacaaattgaaagatgctcaa
gagcagctatcaaggctgaaagacgaggagctaagtgccacagctgttaaagcacagttt
gagaaacagctgttgacagagagaacgctcaagactcaggctgtgaataagttggctgag
atcatgaatcgaaaagaacctatcaagcgtggcagtgacacagacgtgcgaaggaaagag
aaggagaatagaaagctgcacatggaactgaagtctgagcgagaaaaattgacccagcag
atgatcaagtaccagaaggaactgaatgaaatgcaggctcaaatagctgaggagagccag
attcgaattgaactgcagatgacactagacagtaaggacagcgacatcgagcagctgcgg
tcgcagctccaggccctgcacattggcctggacagctccagcatcggcagtgggccaggg
gacacggaggcagaggacgggtttccagagtcaagattagaaggatggctttcgttacct
gtgcgaaacaacacgaagaaatttggatgggttaagaagtacgtgattgtgagcagtaag
aagattcttttctatgacagtgaacaagataaagagcagtctaacccttacatggtttta
gatatagacaaattatttcatgtccgaccggttacacagacggatgtctatagagcagat
gctaaagaaattccaaggatattccagatcctgtatgccaatgaaggagagagcaagaag
gaacaggagtttccagtggaaccagtgggagagaaatcgaattacatctgccacaaaggg
catgagttcatccccaccctgtaccacttcccgaccaactgcgaggcctgcatgaagcca
ctgtggcacatgttcaagccccctcccgctctggagtgccgccgctgccacatcaaatgt
cacaaagaccacttggacagaaaggaagagatcatagcgccgtgcaaagtgtattacgac
atatccacggcaaagaatctgctgttactcgccaactccacagaggagcagcagaggtgg
gtgagccgcctggtgaagaagatccctaagaagcccccagcacccgacccctttgcgcgt
tcgtcacccaggacctccatgaagatcccgcagaaccagtcggtccggcggcccagccgg
cagcttgcccccaacaagcccagctaa
DBGET
integrated database retrieval system
