KEGG   Heterocephalus glaber (naked mole-rat): 101724587
Entry
101724587         CDS       T02812                                 
Symbol
Sqstm1
Name
(RefSeq) sequestosome 1
  KO
K14381  sequestosome 1
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl04137  Mitophagy - animal
hgl04140  Autophagy - animal
hgl04217  Necroptosis
hgl04218  Cellular senescence
hgl04380  Osteoclast differentiation
hgl05014  Amyotrophic lateral sclerosis
hgl05022  Pathways of neurodegeneration - multiple diseases
hgl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101724587 (Sqstm1)
   04137 Mitophagy - animal
    101724587 (Sqstm1)
  09143 Cell growth and death
   04217 Necroptosis
    101724587 (Sqstm1)
   04218 Cellular senescence
    101724587 (Sqstm1)
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101724587 (Sqstm1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101724587 (Sqstm1)
   05022 Pathways of neurodegeneration - multiple diseases
    101724587 (Sqstm1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101724587 (Sqstm1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hgl04131]
    101724587 (Sqstm1)
   03029 Mitochondrial biogenesis [BR:hgl03029]
    101724587 (Sqstm1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hgl04147]
    101724587 (Sqstm1)
Membrane trafficking [BR:hgl04131]
 Autophagy
  Mitophagy
   Cargo receptors
    101724587 (Sqstm1)
  Pexophagy
    101724587 (Sqstm1)
  Aggrephagy
    101724587 (Sqstm1)
  Xenophagy
    101724587 (Sqstm1)
  ER-phagy
   ER-phagy recepters
    101724587 (Sqstm1)
  Other autophagy associated proteins
   Midbophagy
    101724587 (Sqstm1)
Mitochondrial biogenesis [BR:hgl03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    101724587 (Sqstm1)
Exosome [BR:hgl04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   101724587 (Sqstm1)
SSDB
Motif
Pfam: UBA_5 PB1 ZZ
Other DBs
NCBI-GeneID: 101724587
NCBI-ProteinID: XP_004836787
UniProt: A0AAX6NTV6
LinkDB
Position
Un
AA seq 437 aa
MASLTVKAYLLGKEEAAREIRRFSFGFSPESQAEAEEAAAAPGPCERLLRRVAALFPGLR
PGGFQAHYRDEDGDLVAFSSDEELMMAMSYVKDDIFRIYIKEKKEYRREHRPHCAQEVPH
PMVHPNVICDGCDGPVVGTRYKCSVCPNYDLCGACEGKGIHREHNKLPLASPLEHFAEGF
AHSRWFRKLKHGHCRWPGWEMGPPGHWSPRPRVGDARPRAESASGPSEDPSVNFLKNVGE
SVAAALSPLGIEVDIDVEHGGKRSRLTSISPESSSTDDKGSSQPSSCSSEPSKPEGSGKG
IAQSLAEQMRKIALEPTGQPEEQMESDNCSGGDEDWTHLSSKEVDPSTGELQSLQMPESE
ELSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNY
DIGAALDTIQYSKHPPL
NT seq 1314 nt   +upstreamnt  +downstreamnt
atggcgtcgctcaccgtgaaggcctacctactgggcaaggaggaggcggcgcgcgagatc
cgccgcttcagcttcggcttcagccccgagtcgcaggcggaggccgaggaggcggcggcg
gcccccgggccctgcgagcggctgctgaggcgggtggccgccctgttcccgggcctgcgg
cccggcggcttccaggcgcactaccgcgatgaggacggggacttggtggctttttccagt
gatgaggagctgatgatggccatgtcttatgtgaaggacgacatcttccgcatctacatt
aaagagaagaaagagtaccggagggagcaccgcccccactgtgcgcaggaagtgcctcac
cccatggtacaccccaacgtgatctgcgacggctgtgacgggcctgtggtgggaactcgg
tacaagtgcagtgtgtgccccaactacgacctgtgtggcgcctgcgaggggaaaggcatt
cacagggagcacaacaagctcccgctggccagccccctggagcactttgctgagggcttc
gctcacagccgctggttccggaagctgaaacatgggcattgccggtggcctggctgggag
atgggcccaccaggccactggagcccacgtcctcgagtgggagatgcccgccccagggca
gagtcagcttctggcccatcagaggatcccagtgtaaatttcctgaagaacgtaggggag
agtgtggcagctgccctgagccctctgggcattgaagttgacattgacgtggagcacgga
gggaagaggagccgcctgacatccatctccccggagagctccagcacagatgacaagggc
agctcccagccaagcagctgctcttctgaaccaagcaagccagagggcagtggcaagggc
atagcgcagtctctggcagagcagatgagaaagatcgccctggagcccacagggcagccc
gaggagcagatggagtctgacaactgttcgggaggagacgaggactggactcatctgtcc
tcaaaggaagtggacccctccaccggggagcttcagtccctccagatgccagagtcggaa
gagctgagctctctggacccttcccaggaggggcccacagggctgaaggaggctgccttg
tacccgcacctcccaccagaggctgacccccggctgatcgagtcactgtcccagatgctg
tccatgggcttctctgatgaaggcggctggctcacccgcctcctgcagaccaagaactac
gacattggggctgccctggacaccatccagtactccaagcacccgccactgtga

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