Halomonas halophila: QWG60_08485
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Entry
QWG60_08485 CDS
T09170
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
hhao
Halomonas halophila
Pathway
hhao00270
Cysteine and methionine metabolism
hhao00450
Selenocompound metabolism
hhao00670
One carbon pool by folate
hhao01100
Metabolic pathways
hhao01110
Biosynthesis of secondary metabolites
hhao01230
Biosynthesis of amino acids
hhao04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
hhao00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
QWG60_08485 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
QWG60_08485 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
QWG60_08485 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
QWG60_08485 (metH)
04980 Cobalamin transport and metabolism
QWG60_08485 (metH)
Enzymes [BR:
hhao01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
QWG60_08485 (metH)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
HemY_N
Motif
Other DBs
NCBI-ProteinID:
WJY05758
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Position
1844490..1848191
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AA seq
1233 aa
AA seq
DB search
MAAVPTPLTASLTDSLRHRILMLDGGMGTMLQNAALSEEEFRGERFADWPTDLKGNNDLL
ALTCPDLVTRIHRDYLEAGADIVETNTFNSTRLSQADYGMEDLVAELNRESARLARAVCD
AVAEETGVPRYVAGVLGPTSRTASLSPDVNDPAKRNVTFDELRDNYREAAEALIEGGSDL
ILIETIFDTLNAKAAIYALEELFEDRGERLPVMISGTITDASGRTLSGQTTEAFWNSVRH
AKPISVGLNCALGAEELRPYLQELSDKADTFVSAHPNAGLPNEFGEYDQTPEEMAAIVAD
FAASGLVNIIGGCCGSTPEHIAAIHRAIRDTAPREVPERALACRLSGLEPFNIAHDSLFV
NVGERTNVTGSARFKRLIKEEDYTTALEVALEQVENGAQVIDVNMDEGMLESQEAMVRFL
NLIAGEPDIARVPIMVDSSKWEIVEAGLKCIQGKAVVNSISLKEGEDIFREQATRCMRYG
AAIVVMAFDEEGQADTFARKTEICQRAYRLLVDEIGFPAEDIIFDPNIFAIATGIEEHDN
YAVDFIEATRWIREHLPHAMVSGGVSNVSFSFRGNNPVREAIHSVFLYHAIRAGLTMGIV
NAGQLAVYDDLPEALREAVEDVVLNHRSDSTERLLEIADEYKGDGSGGAKKEDLEWRNEE
VEKRIEHALVKGITAYIEEDTELARQRAARPIEVIEGPLMDGMNVVGDLFGAGKMFLPQV
VKSARVMKQAVAYLLPYIEAEKSEDTQTKGKIVMATVKGDVHDIGKNIVGVVLQCNNYEV
IDLGVMVPAEKILQTAREENADIIGLSGLITPSLDEMVHVAKEMQRQGFELPLLIGGATT
SKAHTAVKIEPGYEHPVIYVTDASRAVGVAGKLLSPALKPEYVAEIRAEYEVVRERNAKR
RPKAADLSYAEARARKPVLDWDGYTPPAPGFTGLKVFEDYDLNELVERIDWTPFFMSWEL
AGKYPKILDDEVVGEAARSLFADAQAMLTKLIDEGLVHARGVIGQWPANAVDDDVIEVYA
DESRSEVIERLHHIRQQTTKNREGVCYSLADFIAPKAPGKPDWIGGFAVTTGHGVEELAN
RYKAAGDDYNAIMVQALADRLAEAFAERMHERVRKEFWGYAADETLDNEALIAEKYQGIR
PAPGYPACPDHTEKATLFRLLEAEANAGLELTDSFAMWPAAAVSGWYFAHPQSKYFSTGK
ITRDQVEALAERKGMTQAEMERWLSPVLSYDPS
NT seq
3702 nt
NT seq
+upstream
nt +downstream
nt
atggccgccgttccgactcccctgaccgcttcgctgaccgacagtcttcgccaccgcatc
ctgatgctcgacggcggcatgggcaccatgctgcagaatgccgcgctgtcggaggaagag
ttccgcggggagcgcttcgccgactggcccaccgatctaaagggcaacaacgacctgctg
gcactgacctgcccggacctggtaacgcgcatccaccgcgactatctggaagccggcgcc
gacatcgtcgagaccaacaccttcaacagcacccgcctgtcccaagcagactacggcatg
gaagacctggtcgccgagctcaaccgcgagtcggcccgcctggcccgtgcggtctgcgac
gccgtggccgaggaaaccggcgtgccacgctacgtggccggcgtgctgggcccgacctcg
cgcaccgcctcgctgtcgccggacgtcaatgacccggccaagcgcaacgtcaccttcgac
gagctgcgggacaactatcgcgaggccgccgaggcgctgatcgagggcggcagcgacctg
attctgatcgagaccatcttcgacactctcaacgccaaggccgccatctacgccctggaa
gagctgttcgaggatcgcggcgagcggctgccggtgatgatctccggcaccatcaccgac
gcttccggccgcaccctgtcgggccagaccaccgaggcgttctggaattcggtgcgtcac
gccaagccgatctccgtgggcctgaactgcgcgctgggcgccgaggagctgcgcccctat
ctgcaggagctctccgacaaggccgacaccttcgtctcggcgcaccccaacgccgggctg
cccaacgagttcggcgagtacgaccagacgccggaggagatggccgccatcgtcgccgac
ttcgccgccagcggcctggtcaacatcatcggcggctgctgcggctccacccccgagcac
atcgccgccatccatcgggcgatccgggacaccgcgccccgtgaagtgcccgagcgcgcg
ctggcctgccggctgtccggcctcgagccgttcaacatcgcccacgactcgctgttcgtg
aacgtcggcgagcgcaccaacgtcaccggctcggcgcgcttcaagcgcctgatcaaggaa
gaggactacaccaccgccctggaggtggccctggagcaggtcgagaacggcgcccaggtc
atcgacgtcaacatggacgagggcatgctggagtcccaggaagccatggtgcgattcctc
aacctgatcgccggcgagcccgacatcgcccgggtgccgatcatggtcgactcctccaag
tgggagatcgtcgaggccggcctcaagtgcattcagggcaaggcggtggtcaactcgatc
tcgctgaaggaaggcgaggacatcttccgcgagcaggccacccgctgcatgcgctacggc
gccgccatcgtggtgatggccttcgacgaggaaggccaggccgacaccttcgcgcgcaag
accgagatctgccagcgcgcctatcgcctgctggtcgacgagatcggcttccctgccgaa
gacatcatcttcgaccccaacatcttcgccatcgccaccggcatcgaggagcacgacaac
tacgccgtcgacttcatcgaggccacccgctggatccgcgagcacctgccccacgcgatg
gtctccggcggggtgtcgaacgtgtcgttctcgttccgcggcaacaacccggtgcgcgag
gcgatccactcggtgttcctctaccatgccatccgcgccgggctgaccatgggcatcgtc
aacgccggccagctggcggtctacgacgacctgcccgaggcgctgcgcgaggcggtcgag
gacgtggtgctcaatcaccgcagcgacagcaccgagcgcctgctggagatcgccgacgaa
tacaagggcgacggttccggcggcgccaagaaggaagacctcgagtggcgcaacgaggag
gtcgagaagcgcatcgagcacgccctggtcaagggcatcaccgcctatatcgaggaggat
accgagctcgcccgccagcgggccgcgcgccccatcgaggtgatcgaaggaccgctgatg
gacggcatgaatgtggtcggcgacctgttcggtgccggcaagatgttcctgccccaggtg
gtcaagtcggcgcgggtcatgaagcaggcggtggcctacctgctgccttacatcgaggcg
gaaaagagcgaggatactcaaaccaagggcaagatcgtcatggccacggtcaagggcgac
gtccacgacatcggcaagaacatcgtcggcgtggtcctacagtgcaacaactacgaggtg
atcgacctcggcgtgatggtgccggcggagaagattctgcagaccgccagggaagagaac
gccgacatcatcggcctctccgggctgatcaccccgtcgctggacgagatggtccacgtg
gccaaggagatgcagcgccagggcttcgagctcccgctgctgatcggtggcgccaccacc
tccaaggcccataccgcggtcaagatcgagccgggctacgagcatcccgtgatctacgtc
accgacgcctcgcgggccgtgggcgtggccggcaagctgctgtcgccggcgctgaaaccg
gagtacgtggccgagatccgcgccgagtacgaggtcgtgcgcgagcgcaacgccaagcgt
cgccccaaggcggccgacctcagctacgccgaggcccgtgcgcgcaagccggtcctcgac
tgggacggctacacaccgccggcgcccggcttcaccggcctcaaggtgttcgaggactac
gacctcaacgagctggtcgagcgcatcgactggacgccgttcttcatgagctgggagctg
gccggcaagtatccgaagatcctcgacgacgaggtggtcggcgaagcggcccgcagcctg
ttcgccgacgcccaggcgatgttgaccaagctgatcgacgaggggctggttcatgcccgc
ggcgtgatcggccagtggccggccaacgccgtcgatgacgacgtcatcgaggtctacgcc
gacgagtcgcgcagcgaggtcatcgagcggctgcaccatatccgccagcagaccaccaag
aaccgcgagggcgtctgctacagcctggccgacttcatcgcgcccaaggcacccggcaag
ccggactggatcggcggcttcgccgtcaccaccggccacggcgtcgaggagctcgccaac
cgctacaaggccgccggcgacgactacaacgccatcatggtccaggcgctggccgaccgc
ctcgccgaggccttcgccgagcgcatgcacgagcgggtgcgcaaggagttctggggctac
gccgccgacgagaccctcgacaacgaggcgctgatcgccgagaagtaccagggcatccgc
ccggcgccgggctatccggcctgccccgaccacaccgagaaggcgaccctgttccggctg
ctcgaggccgaggccaacgccggcctcgagctcaccgacagcttcgccatgtggcccgcc
gccgcggtgtccggctggtacttcgcccacccgcagtcgaagtacttctcgaccggcaag
atcacccgcgaccaggtcgaggcgctggccgagcgcaagggcatgacgcaggccgagatg
gagcgttggctgtcgccggtgctttcctacgaccccagctga
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