KEGG   Halomonas halophila: QWG60_08485
Entry
QWG60_08485       CDS       T09170                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
hhao  Halomonas halophila
Pathway
hhao00270  Cysteine and methionine metabolism
hhao00450  Selenocompound metabolism
hhao00670  One carbon pool by folate
hhao01100  Metabolic pathways
hhao01110  Biosynthesis of secondary metabolites
hhao01230  Biosynthesis of amino acids
hhao04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:hhao00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    QWG60_08485 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    QWG60_08485 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    QWG60_08485 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    QWG60_08485 (metH)
   04980 Cobalamin transport and metabolism
    QWG60_08485 (metH)
Enzymes [BR:hhao01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     QWG60_08485 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding HemY_N
Other DBs
NCBI-ProteinID: WJY05758
LinkDB
Position
1844490..1848191
AA seq 1233 aa
MAAVPTPLTASLTDSLRHRILMLDGGMGTMLQNAALSEEEFRGERFADWPTDLKGNNDLL
ALTCPDLVTRIHRDYLEAGADIVETNTFNSTRLSQADYGMEDLVAELNRESARLARAVCD
AVAEETGVPRYVAGVLGPTSRTASLSPDVNDPAKRNVTFDELRDNYREAAEALIEGGSDL
ILIETIFDTLNAKAAIYALEELFEDRGERLPVMISGTITDASGRTLSGQTTEAFWNSVRH
AKPISVGLNCALGAEELRPYLQELSDKADTFVSAHPNAGLPNEFGEYDQTPEEMAAIVAD
FAASGLVNIIGGCCGSTPEHIAAIHRAIRDTAPREVPERALACRLSGLEPFNIAHDSLFV
NVGERTNVTGSARFKRLIKEEDYTTALEVALEQVENGAQVIDVNMDEGMLESQEAMVRFL
NLIAGEPDIARVPIMVDSSKWEIVEAGLKCIQGKAVVNSISLKEGEDIFREQATRCMRYG
AAIVVMAFDEEGQADTFARKTEICQRAYRLLVDEIGFPAEDIIFDPNIFAIATGIEEHDN
YAVDFIEATRWIREHLPHAMVSGGVSNVSFSFRGNNPVREAIHSVFLYHAIRAGLTMGIV
NAGQLAVYDDLPEALREAVEDVVLNHRSDSTERLLEIADEYKGDGSGGAKKEDLEWRNEE
VEKRIEHALVKGITAYIEEDTELARQRAARPIEVIEGPLMDGMNVVGDLFGAGKMFLPQV
VKSARVMKQAVAYLLPYIEAEKSEDTQTKGKIVMATVKGDVHDIGKNIVGVVLQCNNYEV
IDLGVMVPAEKILQTAREENADIIGLSGLITPSLDEMVHVAKEMQRQGFELPLLIGGATT
SKAHTAVKIEPGYEHPVIYVTDASRAVGVAGKLLSPALKPEYVAEIRAEYEVVRERNAKR
RPKAADLSYAEARARKPVLDWDGYTPPAPGFTGLKVFEDYDLNELVERIDWTPFFMSWEL
AGKYPKILDDEVVGEAARSLFADAQAMLTKLIDEGLVHARGVIGQWPANAVDDDVIEVYA
DESRSEVIERLHHIRQQTTKNREGVCYSLADFIAPKAPGKPDWIGGFAVTTGHGVEELAN
RYKAAGDDYNAIMVQALADRLAEAFAERMHERVRKEFWGYAADETLDNEALIAEKYQGIR
PAPGYPACPDHTEKATLFRLLEAEANAGLELTDSFAMWPAAAVSGWYFAHPQSKYFSTGK
ITRDQVEALAERKGMTQAEMERWLSPVLSYDPS
NT seq 3702 nt   +upstreamnt  +downstreamnt
atggccgccgttccgactcccctgaccgcttcgctgaccgacagtcttcgccaccgcatc
ctgatgctcgacggcggcatgggcaccatgctgcagaatgccgcgctgtcggaggaagag
ttccgcggggagcgcttcgccgactggcccaccgatctaaagggcaacaacgacctgctg
gcactgacctgcccggacctggtaacgcgcatccaccgcgactatctggaagccggcgcc
gacatcgtcgagaccaacaccttcaacagcacccgcctgtcccaagcagactacggcatg
gaagacctggtcgccgagctcaaccgcgagtcggcccgcctggcccgtgcggtctgcgac
gccgtggccgaggaaaccggcgtgccacgctacgtggccggcgtgctgggcccgacctcg
cgcaccgcctcgctgtcgccggacgtcaatgacccggccaagcgcaacgtcaccttcgac
gagctgcgggacaactatcgcgaggccgccgaggcgctgatcgagggcggcagcgacctg
attctgatcgagaccatcttcgacactctcaacgccaaggccgccatctacgccctggaa
gagctgttcgaggatcgcggcgagcggctgccggtgatgatctccggcaccatcaccgac
gcttccggccgcaccctgtcgggccagaccaccgaggcgttctggaattcggtgcgtcac
gccaagccgatctccgtgggcctgaactgcgcgctgggcgccgaggagctgcgcccctat
ctgcaggagctctccgacaaggccgacaccttcgtctcggcgcaccccaacgccgggctg
cccaacgagttcggcgagtacgaccagacgccggaggagatggccgccatcgtcgccgac
ttcgccgccagcggcctggtcaacatcatcggcggctgctgcggctccacccccgagcac
atcgccgccatccatcgggcgatccgggacaccgcgccccgtgaagtgcccgagcgcgcg
ctggcctgccggctgtccggcctcgagccgttcaacatcgcccacgactcgctgttcgtg
aacgtcggcgagcgcaccaacgtcaccggctcggcgcgcttcaagcgcctgatcaaggaa
gaggactacaccaccgccctggaggtggccctggagcaggtcgagaacggcgcccaggtc
atcgacgtcaacatggacgagggcatgctggagtcccaggaagccatggtgcgattcctc
aacctgatcgccggcgagcccgacatcgcccgggtgccgatcatggtcgactcctccaag
tgggagatcgtcgaggccggcctcaagtgcattcagggcaaggcggtggtcaactcgatc
tcgctgaaggaaggcgaggacatcttccgcgagcaggccacccgctgcatgcgctacggc
gccgccatcgtggtgatggccttcgacgaggaaggccaggccgacaccttcgcgcgcaag
accgagatctgccagcgcgcctatcgcctgctggtcgacgagatcggcttccctgccgaa
gacatcatcttcgaccccaacatcttcgccatcgccaccggcatcgaggagcacgacaac
tacgccgtcgacttcatcgaggccacccgctggatccgcgagcacctgccccacgcgatg
gtctccggcggggtgtcgaacgtgtcgttctcgttccgcggcaacaacccggtgcgcgag
gcgatccactcggtgttcctctaccatgccatccgcgccgggctgaccatgggcatcgtc
aacgccggccagctggcggtctacgacgacctgcccgaggcgctgcgcgaggcggtcgag
gacgtggtgctcaatcaccgcagcgacagcaccgagcgcctgctggagatcgccgacgaa
tacaagggcgacggttccggcggcgccaagaaggaagacctcgagtggcgcaacgaggag
gtcgagaagcgcatcgagcacgccctggtcaagggcatcaccgcctatatcgaggaggat
accgagctcgcccgccagcgggccgcgcgccccatcgaggtgatcgaaggaccgctgatg
gacggcatgaatgtggtcggcgacctgttcggtgccggcaagatgttcctgccccaggtg
gtcaagtcggcgcgggtcatgaagcaggcggtggcctacctgctgccttacatcgaggcg
gaaaagagcgaggatactcaaaccaagggcaagatcgtcatggccacggtcaagggcgac
gtccacgacatcggcaagaacatcgtcggcgtggtcctacagtgcaacaactacgaggtg
atcgacctcggcgtgatggtgccggcggagaagattctgcagaccgccagggaagagaac
gccgacatcatcggcctctccgggctgatcaccccgtcgctggacgagatggtccacgtg
gccaaggagatgcagcgccagggcttcgagctcccgctgctgatcggtggcgccaccacc
tccaaggcccataccgcggtcaagatcgagccgggctacgagcatcccgtgatctacgtc
accgacgcctcgcgggccgtgggcgtggccggcaagctgctgtcgccggcgctgaaaccg
gagtacgtggccgagatccgcgccgagtacgaggtcgtgcgcgagcgcaacgccaagcgt
cgccccaaggcggccgacctcagctacgccgaggcccgtgcgcgcaagccggtcctcgac
tgggacggctacacaccgccggcgcccggcttcaccggcctcaaggtgttcgaggactac
gacctcaacgagctggtcgagcgcatcgactggacgccgttcttcatgagctgggagctg
gccggcaagtatccgaagatcctcgacgacgaggtggtcggcgaagcggcccgcagcctg
ttcgccgacgcccaggcgatgttgaccaagctgatcgacgaggggctggttcatgcccgc
ggcgtgatcggccagtggccggccaacgccgtcgatgacgacgtcatcgaggtctacgcc
gacgagtcgcgcagcgaggtcatcgagcggctgcaccatatccgccagcagaccaccaag
aaccgcgagggcgtctgctacagcctggccgacttcatcgcgcccaaggcacccggcaag
ccggactggatcggcggcttcgccgtcaccaccggccacggcgtcgaggagctcgccaac
cgctacaaggccgccggcgacgactacaacgccatcatggtccaggcgctggccgaccgc
ctcgccgaggccttcgccgagcgcatgcacgagcgggtgcgcaaggagttctggggctac
gccgccgacgagaccctcgacaacgaggcgctgatcgccgagaagtaccagggcatccgc
ccggcgccgggctatccggcctgccccgaccacaccgagaaggcgaccctgttccggctg
ctcgaggccgaggccaacgccggcctcgagctcaccgacagcttcgccatgtggcccgcc
gccgcggtgtccggctggtacttcgcccacccgcagtcgaagtacttctcgaccggcaag
atcacccgcgaccaggtcgaggcgctggccgagcgcaagggcatgacgcaggccgagatg
gagcgttggctgtcgccggtgctttcctacgaccccagctga

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