Harpia harpyja (harpy eagle): 128137906
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Entry
128137906 CDS
T10541
Symbol
HMGCS1
Name
(RefSeq) hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X1
KO
K01641
hydroxymethylglutaryl-CoA synthase [EC:
2.3.3.10
]
Organism
hhar Harpia harpyja (harpy eagle)
Pathway
hhar00280
Valine, leucine and isoleucine degradation
hhar00650
Butanoate metabolism
hhar00900
Terpenoid backbone biosynthesis
hhar01100
Metabolic pathways
hhar03320
PPAR signaling pathway
Module
hhar_M00095
C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
hhar00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
128137906 (HMGCS1)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
128137906 (HMGCS1)
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
128137906 (HMGCS1)
09150 Organismal Systems
09152 Endocrine system
03320 PPAR signaling pathway
128137906 (HMGCS1)
Enzymes [BR:
hhar01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.10 hydroxymethylglutaryl-CoA synthase
128137906 (HMGCS1)
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Motif
Pfam:
HMG_CoA_synt_C
HMG_CoA_synt_N
ACP_syn_III
Lectin_C_term
Cullin
Motif
Other DBs
NCBI-GeneID:
128137906
NCBI-ProteinID:
XP_052635124
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All DBs
Position
Z:100790613..100803780
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AA seq
531 aa
AA seq
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MGFRNVSATMPGSLPVNAESCWPKDVGIVALEIYFPSQYVDQTELEKYDGVDAGKYTIGL
GQSKMGFCSDREDINSLCLTVVQKLMERNSLSYDCIGRLEVGTETIIDKSKSVKTVLMQL
FEESGNTDVEGIDTTNACYGGTAALFNAINWIESSSWDGRYALVVAGDIAVYASGNARPT
GGAGAVAMLVGPNAPLIFERGLRGTHMQHAYDFYKPDMVSEYPVVDGKLSIQCYLSALDR
CYTVYRNKIHAQWQKEGTDRRFTLNDFGFMIFHSPYCKLVQKSVARLLLNDFLSDQNPET
ANGVFSGLEAFRDVKLEDTYFDRDVEKAFMKASAEIFNQKTKDSLLVSNQNGNMYTPSVY
GCLASLLAQYSPEQLAGQRISVFSYGSGFAATLYSIRVTQDATPGSALDKITASLSDLKT
RLDSRKCIAPDVFAENMKIRQETHHLANYIPQCSVEDLFEGTWYLVRVDEKHRRTYARRP
LMGDGPLEAGVEVVHPGIVHEHIPSPAKKVPRIPATTESEGVTVAISNGEH
NT seq
1596 nt
NT seq
+upstream
nt +downstream
nt
atgggattccgcaacgtatctgccacaatgcctgggtctcttccagtgaatgctgaatcc
tgttggcccaaagatgtgggaattgttgcactggaaatatattttccctctcagtatgtt
gaccagacagagctggagaagtatgatggtgtggatgctgggaaatacaccattgggcta
ggccagtcaaagatgggcttctgctctgaccgggaggatatcaattctctctgcttgact
gtggttcagaagctcatggagaggaacagcctttcctatgattgtatcgggagattagaa
gttggaacggagacgataattgataaatcaaaatctgtaaagactgtcctgatgcaactt
tttgaagaatctggtaatacggatgtagaaggaatcgacaccaccaatgcatgctatgga
ggcactgctgctctttttaatgctattaactggattgagtccagttcttgggatggacgc
tatgcacttgttgttgctggagacattgctgtgtatgccagtggaaatgccaggccaaca
ggtggagctggtgctgttgctatgctagttggtccaaatgctccgttaatttttgagaga
gggttgcgtggaacccacatgcagcatgcatatgacttctataaacctgatatggtctct
gaatatcctgtagttgatggcaaactatctatacagtgctacctcagtgcattagatcgc
tgctatactgtctaccgcaacaaaatccatgcccagtggcaaaaggaagggacagacaga
cgtttcaccttgaatgactttggattcatgatcttccattctccctactgtaaactggta
cagaaatctgtggctagactcttgctgaatgactttctcagtgaccagaacccagaaaca
gcaaatggtgttttcagtggtctggaagctttcagggatgtaaaacttgaagatacgtat
tttgacagagatgtggaaaaagcttttatgaaagctagcgcagagatcttcaatcagaaa
accaaagattcattacttgtatccaaccagaatggaaatatgtataccccttcagtctat
ggttgccttgcctctcttctagcccagtactccccagagcagcttgcaggacagagaatc
agtgtgttctcatatggctctggttttgctgctacgctgtattccatcagagttacccag
gatgccactcctggttctgcactggacaaaataactgccagcctttctgatctcaaaaca
agacttgactcaagaaaatgtattgcacctgatgtctttgctgaaaacatgaagattaga
caggaaacacatcatttggccaactatattccgcagtgttcggtagaagatctgttcgag
ggaacatggtaccttgtgcgtgtggatgagaaacacaggagaacttacgcccggcgccca
ctcatgggcgatggacctctggaggcaggagtcgaagttgtccacccaggcattgttcat
gagcacatcccaagccctgctaagaaagtgccaagaatccctgcaacaacagaatctgaa
ggcgttactgttgccatttccaatggggagcattaa
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