Harpia harpyja (harpy eagle): 128142824
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Entry
128142824 CDS
T10541
Symbol
PLCG1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
KO
K01116
phosphatidylinositol phospholipase C, gamma-1 [EC:
3.1.4.11
]
Organism
hhar Harpia harpyja (harpy eagle)
Pathway
hhar00562
Inositol phosphate metabolism
hhar01100
Metabolic pathways
hhar04012
ErbB signaling pathway
hhar04020
Calcium signaling pathway
hhar04070
Phosphatidylinositol signaling system
hhar04370
VEGF signaling pathway
Module
hhar_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
Enzymes [BR:
hhar01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
128142824 (PLCG1)
Membrane trafficking [BR:
hhar04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
128142824 (PLCG1)
Endocytosis
Macropinocytosis
Phospholipase C
128142824 (PLCG1)
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Ortholog
Paralog
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GFIT
Other DBs
NCBI-GeneID:
128142824
NCBI-ProteinID:
XP_052645369
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Position
1:complement(40998029..41050046)
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AA seq
1283 aa
AA seq
DB search
MAAGPGSGPGAPSEAEAAHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQVTWSRG
SEKIEGAVDIREIKEIRPGKNSRDFDRYQEDPCFRPDQSHCFVVLYGTEFRLKTLSLQAT
SEDEVNMWIKGLNWLVADTLRAATPLQIERWLRKQFYSLDRNREDRISAKDLKNMLSQVN
YRVPNMRFLRERLTDVEQRNGDITYGQFAQLYRSLMFSAQKMMDVPFLERGGERSEHFRV
SLLELQKFLLEYQRELWAADTLQVQEFMFNFLRDPLREIDEPYFSLDEFLTFLFSKENSI
WNSQLDMVCLENMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCW
DGPDGMPVIYHGHTLTTKIKFSDVLVTIKEHAFVTSDFPVILSIEDHCSIAQQRNMAQNF
KKVFGDMLLTKPVDISADGLPSPNQLKRKILIKHKKLAEGSAYEELPTSVMYSENDISNS
IKNGILYLEDPINHEWNPHYFVLTSSKIYYSGETTSDQGNEDEEEQKEVSNSTELHSTEK
WFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCR
IHSRQDAGSPKFFLTDNLVFDSLYDLITHYQEVPLRCNEFEMRLTEPVPQTNAHESKEWY
HANLTRAQAEHMLMRVPRDGAFLVRKRSEPSSYAISFRAEGKIKHCRVQQEGQTVLLGNS
EFESLVDLISYYEKHPLYRKMKLRYPINEETLEKIGTAEPDYGALYEGRHPGFYVEANPM
PTFKCAVKALFDYKAQREDELTFTKNAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEI
TGPSSLEPEREQQLDENSPLGDLLGGVLDVPSCQIAIRPEGKNNRLFVFSISMASVSRLS
LDVAADTHEDLLDWVKKIREAAQTADARLSEGKMMERRKKIALELSELVVYCRPVPFDEE
KIGTERACYRDMSSFPETKAEKYVNKIKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPM
WICGSQLVALNFQTPDKPMQMNQALFMSSGQCGYVLQPANMRDDIFDPFDKSTLRGVEPL
SISIEVLGARHLPKNGRGIVCPFVEVEVSGAEYDNVKQKTEIVADNGLNPLWTPKQFHFQ
VSNPDFAFLRFVVYEEDMFSDENFLAQATFLVKGLKTGFRAVPLKNNYSENLELASLLVK
IDVFPSKQENGEINLFSASALRERAGDASNQLLASRGREGSFESRYQQPFEDFRVSQEQL
ADHFESRERRVLRRTRVNGDNRL
NT seq
3852 nt
NT seq
+upstream
nt +downstream
nt
atggcggccgggccgggcagcggccccggggcgcccagcgaggcggaggcagcgcacctc
tgccgcagcctggaggtgggcaccgtcatgaccctcttctactctaaaaagtcgcagcga
cccgaacggaaaactttccaggtgaagctggagacgcggcaggtcacctggagccgcggc
tccgagaagatcgagggagccgtggatattcgtgaaatcaaagagattcgtccaggaaaa
aactcacgtgattttgaccgataccaggaggatccatgtttccgacctgaccagtcccac
tgctttgttgtcctctatggcacagaattccggctgaagaccctcagcttgcaagccact
tcggaagatgaggtcaatatgtggatcaaggggttgaactggctggtggcagacactcta
agggctgccacccccctgcagattgaaaggtggctccggaagcagttctactcactggat
cgtaaccgggaagacaggatctctgccaaggatctgaagaacatgctgtctcaggtcaac
taccgggtccccaacatgaggttcctgcgggagagactcacggatgtggagcagaggaac
ggggatatcacgtacgggcagtttgcacagctctaccgcagcctgatgttcagcgcacag
aaaatgatggatgtcccgttcctagaaaggggtggagaaaggtccgagcacttcagggtg
tcactgctggagttgcagaagttcttgctggagtaccagagggagctttgggctgcagat
acccttcaggtacaggaattcatgttcaactttctgagagaccctttgagggagattgac
gagccttatttctccctggatgaatttctcaccttcctgttttccaaagagaacagcatc
tggaactcgcaactggacatggtgtgtctggagaatatgaacaacccactctcccattac
tggatctcctcctcacacaacacgtacctgacaggggatcagttctcgagcgagtcctcg
ctggaggcgtacgcccgctgcttgcgcatgggatgccgctgtatcgaattggattgctgg
gacggtcccgatggcatgccggtcatctaccatggacacaccttaaccaccaagatcaag
ttctctgatgtcttggtcactatcaaggaacatgcctttgtcacctccgatttccccgtc
attctgtccattgaggaccactgcagcattgctcagcagaggaacatggctcagaatttc
aagaaggtctttggggacatgctgttgaccaaaccagtagatatttctgctgacggcctt
ccctctccgaaccagctcaagaggaagattctcatcaagcacaagaagctggcagagggc
agtgcttatgaggagttacccacgtccgtaatgtattcagagaatgacatcagcaactcc
atcaagaacgggatcctctacctggaagaccccatcaatcacgagtggaacccacattac
tttgtcctgaccagcagcaagatctattactctggggagacaaccagtgatcaaggaaac
gaggatgaggaagagcaaaaggaggtgagcaacagcactgagctccactccacggagaag
tggtttcacggcaagctgggagcaggacgcgacgggcggcacattgcagagcggcttctg
acagagtactgcatcgagacgggggctcccgacggctctttcctcgtcagagagagcgag
acctttgttggagactacaccctctccttctggcgcaacgggaaggtgcagcactgccgg
atccactcgcggcaggacgccggcagccccaagttcttcctgacggacaacctggtgttc
gacagcctctacgacctcatcacccactaccaggaggtgccgctgaggtgcaacgagttt
gagatgaggctgacggagccagtgccacagaccaacgcccatgagagcaaagagtggtac
cacgccaacctcacccgggcccaagctgagcacatgctgatgagggtgccacgcgacgga
gccttcctggtgcgcaagaggagtgagcccagctcctacgccatctccttcagggcggaa
gggaagatcaaacactgccgagtgcagcaggagggccagaccgtgctgctcggcaactcc
gagttcgagagcctggtggatttgatcagctactatgaaaagcacccactgtaccgcaag
atgaagctgaggtaccccatcaacgaggagacgctggagaagatagggacagcggagccg
gactacggagccctttatgagggacgccaccctgggttctacgtggaagccaaccccatg
cccaccttcaagtgcgcagtcaaagccctgttcgactacaaggcacagcgggaggacgag
ctcaccttcaccaaaaatgccatcatccagaatgtggagaaacaggaaggaggctggtgg
agaggagattatggtggcaagaagcagctgtggttcccttccaactacgtagaggaaatt
actggtcccagcagcctggagccagagcgggagcagcagctggatgagaacagccccctg
ggagacctgctcggaggtgtcctggatgtgccctcctgccagatcgccatccgccccgag
gggaagaacaaccgcctcttcgtcttctccattagcatggcctcagtgtcgcgcttgtcc
cttgatgtggcagccgatacgcatgaggacttgctggactgggtgaagaagatccgggag
gcagcccagacggctgatgcacggctctccgaagggaagatgatggagaggaggaagaag
attgccctggagctttcggagctggtggtctattgccgacctgtgccctttgatgaagag
aagatcggcacagagagggcctgttaccgagatatgtcctccttccccgagaccaaggcg
gaaaagtacgtcaacaagatcaaaggcaagaagttcctgcagtacaaccgcctgcagctc
tcccgcatctaccccaagggccagcgtctcgactcctccaactacgaccccctgcccatg
tggatctgcggcagccagctggtagcactcaacttccagaccccagataagcccatgcag
atgaaccaggccttgttcatgtccagcggccagtgtgggtacgtcttgcagccagccaac
atgcgagatgacatcttcgaccccttcgacaagagcacgctgcggggggttgagccgctc
tccatctccattgaggtcctgggggcccggcaccttcccaaaaatggaagaggaatcgtt
tgtcctttcgtggaggtggaggtgtctggggctgagtatgacaacgttaagcagaaaacc
gagattgtggcggacaatggcctgaaccctctctggaccccgaagcagttccactttcag
gtcagcaaccctgactttgccttcctccgctttgtggtgtacgaggaggacatgttcagc
gatgagaacttcctggctcaggccaccttcctggtgaaaggcttgaagacgggtttccga
gctgtacccctgaagaacaactacagcgagaacctggagctggcttccctgctcgtcaag
atagacgttttcccgagcaagcaggagaatggcgaaataaacctcttcagtgcttcagcc
ctacgggaacgagcaggggatgcttccaatcagctgctggcaagcagaggcagagagggg
tccttcgagtcgcggtaccagcagcccttcgaggacttccgtgtgtcgcaggagcagctg
gctgaccactttgagagccgggagcgaagggtactgcggaggacccgggtcaacggggac
aaccggctgtag
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