Harpia harpyja (harpy eagle): 128143239
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Entry
128143239 CDS
T10541
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
hhar Harpia harpyja (harpy eagle)
Pathway
hhar04120
Ubiquitin mediated proteolysis
hhar04144
Endocytosis
hhar04330
Notch signaling pathway
Brite
Enzymes [BR:
hhar01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
128143239 (ITCH)
Membrane trafficking [BR:
hhar04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
128143239 (ITCH)
Ubiquitin system [BR:
hhar04121
]
Ubiquitin ligases (E3)
HECT type E3
128143239 (ITCH)
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Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
128143239
NCBI-ProteinID:
XP_052646223
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Position
1:45096849..45168639
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AA seq
878 aa
AA seq
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MAGSGSRSGPSSGFSMKSQLQITVISAKLKEKNKWFGPSPYVEVSVDGQSKKTEKCNNTN
SPKWKQHLTVIVTPVSKLNFRVWSHQTLKSDVLLGSAALDIHETLKSNSMKLEQVVVTLH
LVGDREPAEVVGDLSVCLDGMQVDPELLTNGDASSTRSPTQNDSSKVKNDARTNSNGLEG
CEDAAPNENKTVNGSDSPLLTNGNCKPSRPPRPSRPPPPTPRRPTSVAASINGPSSTSTE
SDGASAGSLAGTAANTSSEQSPEGATAATTAPATAALTTPPVSRQVQPVNPPPQALATVS
QGPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPLPPSWERRVDNMGRIYYVDHFTRTT
TWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDFSSTQNKEFDPLGPLPHGWE
KRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTT
YIDPRTGKSALDNGPQIAYVRDFKAKVHYFRFWCQQLAMPQHIKITVSRKTLFEDSFQQI
MSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQIN
PASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESVDPEFY
NSLIWVKENDIEECGLEMFFSVDKEILGEIKSHDLKPNGSNILVTEENKEEYIRLVAEWR
LSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHTIYRHYTRT
SRQIVWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWL
PRSHTCFNRLDLPPYKNYEQLKEKLLFAIEETEGFGQE
NT seq
2637 nt
NT seq
+upstream
nt +downstream
nt
atggctggcagtgggtccagatcaggaccatccagtggattttccatgaaatcacagctt
cagatcactgttatttcagcaaagctaaaagaaaaaaataaatggtttggacctagccct
tatgtggaagtctcagtagatggacagtcaaagaagacagaaaaatgcaacaatacaaat
agccccaagtggaaacagcatctaacagtaattgtgactcctgtaagtaaattaaacttt
cgagtctggagccatcaaacattaaaatctgatgtccttctgggaagtgctgctctggat
attcatgagactttgaaatcaaacagtatgaaacttgagcaggtagtggtgacattgcat
cttgttggtgacagagaaccagcagaagtggtaggagatttgtctgtctgtctagatggg
atgcaggtggatcctgagctcctaaccaatggtgatgcctcaagtacaagaagtcctaca
cagaatgatagctccaaagtaaagaatgatgcacggactaactcaaatggccttgaaggc
tgtgaagatgctgctcccaatgaaaacaagactgttaatggcagtgattctccattgctc
acaaatggaaactgcaaaccttctagacctcccaggccttctagaccacctccacctact
ccccgcagacccacttcagtagctgcaagtataaatggtccttcatccacatccacagaa
agtgatggggccagtgcaggatcgctggcaggtacagctgcaaatacatcttcagaacag
agccctgagggggcaacagctgcaacaacagctcctgcaactgctgcactcaccacacct
ccagtatccagacaagtccagccagtaaatcctccacctcaggcgcttgctacagtcagt
caaggtcctcttccacctggttgggagcaaagagtagaccaacatggtcgagtatactat
gtagatcatgttgaaaaaagaacaacgtgggaccggccagagcctcttcctccaagctgg
gagcgacgagttgacaacatggggagaatttattatgttgaccacttcactagaacaaca
acgtggcagagaccaacattagagtctgtccggaattatgagcagtggcagcttcagcgc
agtcagcttcaaggagctatgcagcagtttaatcagagatttatatatgggaaccaggac
ttttcatccacacagaacaaagagtttgatcctcttggccctctgccacatggatgggaa
aagagaactgacagcaatggcagagtgtattttgtcaatcacaatacacgaatcactcag
tgggaagatcccaggagccagggtcaattaaatgagaaacccttaccagaaggctgggaa
atgcgatttactgtggatggtattccatactttgtggatcacaataggagaaccactaca
tatatagatccccgcacgggcaaatctgctctagacaatggacctcagatagcttatgtg
cgcgatttcaaggcaaaggtccattatttcagattctggtgtcagcaactggcaatgcca
caacacataaagattacagtgagcagaaaaacattatttgaggactcatttcaacagata
atgagcttcagccctcaggatctacggagacgcttatgggttattttccctggtgaagaa
ggcttagattatggaggtgttgcaagggaatggttctttctattgtcacatgaagttttg
aacccaatgtattgcctgtttgaatatgcagggaaagataactactgcttacagataaat
ccagcctcttacattaatccagaccatctgaaatacttccgatttattggaagattcatt
gccatggctttgttccatgggaaattcattgacactggtttctctctgccgttctataaa
cgtatcctaaacaagccagtaggactcaaggatttagaatctgttgacccagagttttac
aactctctcatctgggtaaaagagaatgatattgaagaatgtggcttggaaatgtttttc
tcagttgataaagaaattctaggtgaaatcaaaagccatgatttgaagccaaatggtagc
aacattctggtcacagaagaaaacaaagaagaatacattaggctagtagcagaatggaga
ctttcccgaggtgttgaggagcagacacaggctttctttgaaggctttaatgaaattctg
ccacaacagtatttgcagtattttgatgctaaggaactggaggtgcttctgtgtggaatg
caagaaattgatttgaatgactggcagaggcataccatctaccggcactataccaggacc
agcagacagatagtatggttctggcagtttgtgaaagaaatagataatgagaagagaatg
aggctcttgcagtttgttactggaacatgcagattaccagtgggaggatttgctgacctc
atggggagcaatggaccccaaaaattttgtattgaaaaagttggaaaggaaaactggtta
cctagaagtcatacctgtttcaatcgcttagaccttccaccctataagaattacgagcag
ttgaaggaaaagctgttgttcgcaattgaagaaacagaaggatttgggcaagaatag
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