Harpia harpyja (harpy eagle): 128143239
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Entry
128143239 CDS
T10541
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
hhar Harpia harpyja (harpy eagle)
Pathway
hhar04120
Ubiquitin mediated proteolysis
hhar04144
Endocytosis
hhar04330
Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:
hhar00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
128143239 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
128143239 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
128143239 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hhar04131
]
128143239 (ITCH)
04121 Ubiquitin system [BR:
hhar04121
]
128143239 (ITCH)
Enzymes [BR:
hhar01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
128143239 (ITCH)
Membrane trafficking [BR:
hhar04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
128143239 (ITCH)
Ubiquitin system [BR:
hhar04121
]
Ubiquitin ligases (E3)
HECT type E3
128143239 (ITCH)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
128143239
NCBI-ProteinID:
XP_052646223
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All DBs
Position
1:45096849..45168639
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AA seq
878 aa
AA seq
DB search
MAGSGSRSGPSSGFSMKSQLQITVISAKLKEKNKWFGPSPYVEVSVDGQSKKTEKCNNTN
SPKWKQHLTVIVTPVSKLNFRVWSHQTLKSDVLLGSAALDIHETLKSNSMKLEQVVVTLH
LVGDREPAEVVGDLSVCLDGMQVDPELLTNGDASSTRSPTQNDSSKVKNDARTNSNGLEG
CEDAAPNENKTVNGSDSPLLTNGNCKPSRPPRPSRPPPPTPRRPTSVAASINGPSSTSTE
SDGASAGSLAGTAANTSSEQSPEGATAATTAPATAALTTPPVSRQVQPVNPPPQALATVS
QGPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPLPPSWERRVDNMGRIYYVDHFTRTT
TWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDFSSTQNKEFDPLGPLPHGWE
KRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTT
YIDPRTGKSALDNGPQIAYVRDFKAKVHYFRFWCQQLAMPQHIKITVSRKTLFEDSFQQI
MSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQIN
PASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESVDPEFY
NSLIWVKENDIEECGLEMFFSVDKEILGEIKSHDLKPNGSNILVTEENKEEYIRLVAEWR
LSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHTIYRHYTRT
SRQIVWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWL
PRSHTCFNRLDLPPYKNYEQLKEKLLFAIEETEGFGQE
NT seq
2637 nt
NT seq
+upstream
nt +downstream
nt
atggctggcagtgggtccagatcaggaccatccagtggattttccatgaaatcacagctt
cagatcactgttatttcagcaaagctaaaagaaaaaaataaatggtttggacctagccct
tatgtggaagtctcagtagatggacagtcaaagaagacagaaaaatgcaacaatacaaat
agccccaagtggaaacagcatctaacagtaattgtgactcctgtaagtaaattaaacttt
cgagtctggagccatcaaacattaaaatctgatgtccttctgggaagtgctgctctggat
attcatgagactttgaaatcaaacagtatgaaacttgagcaggtagtggtgacattgcat
cttgttggtgacagagaaccagcagaagtggtaggagatttgtctgtctgtctagatggg
atgcaggtggatcctgagctcctaaccaatggtgatgcctcaagtacaagaagtcctaca
cagaatgatagctccaaagtaaagaatgatgcacggactaactcaaatggccttgaaggc
tgtgaagatgctgctcccaatgaaaacaagactgttaatggcagtgattctccattgctc
acaaatggaaactgcaaaccttctagacctcccaggccttctagaccacctccacctact
ccccgcagacccacttcagtagctgcaagtataaatggtccttcatccacatccacagaa
agtgatggggccagtgcaggatcgctggcaggtacagctgcaaatacatcttcagaacag
agccctgagggggcaacagctgcaacaacagctcctgcaactgctgcactcaccacacct
ccagtatccagacaagtccagccagtaaatcctccacctcaggcgcttgctacagtcagt
caaggtcctcttccacctggttgggagcaaagagtagaccaacatggtcgagtatactat
gtagatcatgttgaaaaaagaacaacgtgggaccggccagagcctcttcctccaagctgg
gagcgacgagttgacaacatggggagaatttattatgttgaccacttcactagaacaaca
acgtggcagagaccaacattagagtctgtccggaattatgagcagtggcagcttcagcgc
agtcagcttcaaggagctatgcagcagtttaatcagagatttatatatgggaaccaggac
ttttcatccacacagaacaaagagtttgatcctcttggccctctgccacatggatgggaa
aagagaactgacagcaatggcagagtgtattttgtcaatcacaatacacgaatcactcag
tgggaagatcccaggagccagggtcaattaaatgagaaacccttaccagaaggctgggaa
atgcgatttactgtggatggtattccatactttgtggatcacaataggagaaccactaca
tatatagatccccgcacgggcaaatctgctctagacaatggacctcagatagcttatgtg
cgcgatttcaaggcaaaggtccattatttcagattctggtgtcagcaactggcaatgcca
caacacataaagattacagtgagcagaaaaacattatttgaggactcatttcaacagata
atgagcttcagccctcaggatctacggagacgcttatgggttattttccctggtgaagaa
ggcttagattatggaggtgttgcaagggaatggttctttctattgtcacatgaagttttg
aacccaatgtattgcctgtttgaatatgcagggaaagataactactgcttacagataaat
ccagcctcttacattaatccagaccatctgaaatacttccgatttattggaagattcatt
gccatggctttgttccatgggaaattcattgacactggtttctctctgccgttctataaa
cgtatcctaaacaagccagtaggactcaaggatttagaatctgttgacccagagttttac
aactctctcatctgggtaaaagagaatgatattgaagaatgtggcttggaaatgtttttc
tcagttgataaagaaattctaggtgaaatcaaaagccatgatttgaagccaaatggtagc
aacattctggtcacagaagaaaacaaagaagaatacattaggctagtagcagaatggaga
ctttcccgaggtgttgaggagcagacacaggctttctttgaaggctttaatgaaattctg
ccacaacagtatttgcagtattttgatgctaaggaactggaggtgcttctgtgtggaatg
caagaaattgatttgaatgactggcagaggcataccatctaccggcactataccaggacc
agcagacagatagtatggttctggcagtttgtgaaagaaatagataatgagaagagaatg
aggctcttgcagtttgttactggaacatgcagattaccagtgggaggatttgctgacctc
atggggagcaatggaccccaaaaattttgtattgaaaaagttggaaaggaaaactggtta
cctagaagtcatacctgtttcaatcgcttagaccttccaccctataagaattacgagcag
ttgaaggaaaagctgttgttcgcaattgaagaaacagaaggatttgggcaagaatag
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