Harpia harpyja (harpy eagle): 128145860
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Entry
128145860 CDS
T10541
Symbol
MLKL
Name
(RefSeq) mixed lineage kinase domain-like protein
KO
K08849
mixed lineage kinase domain-like [EC:
2.7.11.1
]
Organism
hhar Harpia harpyja (harpy eagle)
Pathway
hhar04217
Necroptosis
hhar04623
Cytosolic DNA-sensing pathway
hhar05132
Salmonella infection
Brite
KEGG Orthology (KO) [BR:
hhar00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
128145860 (MLKL)
09150 Organismal Systems
09151 Immune system
04623 Cytosolic DNA-sensing pathway
128145860 (MLKL)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
128145860 (MLKL)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hhar01001
]
128145860 (MLKL)
Enzymes [BR:
hhar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
128145860 (MLKL)
Protein kinases [BR:
hhar01001
]
Serine/threonine kinases: TKL group
Other
128145860 (MLKL)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MLKL_N
PK_Tyr_Ser-Thr
Pkinase
DUF7792
RPW8
Ribosomal_S17_N
Motif
Other DBs
NCBI-GeneID:
128145860
NCBI-ProteinID:
XP_052652585
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All DBs
Position
9:21959394..21965160
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AA seq
485 aa
AA seq
DB search
MDIVEKVLSMAQAIHTQFEQVKCCKHQCQRLVERIQILLEPVRILKAQPPKHISHHEKQL
LKKLLWVLGEAQKLVMKYSQTSWIQKFLRAHSTSEEFVWVNESLEDIAQGLSLLLQAEQK
QAFLEVFQAKTCRKQDAEDLRDDRAFLDQVIATTEEPKDASGEIYIDRQCMESKVDWMQN
ELNKIVHVMDCLKKVNVGKREDITEIERDHLTFYRHLQDTESYDLYEGEYLKYPVAIKIF
KRPLTTDPSKVRDIFEKEIQTLKKFESPNILRMYGICIEEKDGSPCFSIVMEYCKHGTLR
DVLTKQQHLSWEVRIRMALGAARGLYRLHQTEEKSRLHGCICSSKFLVAGDYCVKLSGFE
LCETESSIKRKAKKNWKQVSMLAYIAPENLKDINYPYKRPCEIYSFGIVLWEIATSKIPF
EGCTPQEIMEKICNDHYQAPVGEDCPEDLRKVIDQCRAFDPSQRPSAEEIVDSLADLEKS
RNQGS
NT seq
1458 nt
NT seq
+upstream
nt +downstream
nt
atggacatcgtggagaaggtcctctccatggcccaggccatccacacccaatttgagcag
gtgaaatgctgtaagcaccagtgccagcgccttgtggagcgcatccagattctgctggag
cctgtaaggatcctcaaggctcagccgccaaagcacatctcccaccatgaaaagcaactg
ctgaaaaagctgctctgggtgctgggggaagcccagaaactggtgatgaaatacagccag
accagctggatccagaagttcctgagagcccacagcaccagcgaggagttcgtctgggtg
aatgagagcctggaggacatcgcccaggggctctcactcctgctgcaggcagagcagaag
caggctttcctggaggttttccaggcaaagacatgtcgcaagcaggacgctgaggacctg
agggacgacagggctttcttagaccaggtgattgcaactactgaggagcccaaagatgcg
tccggggagatttacattgacaggcaatgtatggagagcaaggtagactggatgcaaaat
gagctgaacaaaattgtgcatgtgatggactgcttgaagaaggtcaatgttggtaaaaga
gaagacatcactgagatcgagcgggaccacctcaccttctacaggcacctgcaggacacc
gagagttatgacctctacgagggcgaatacctcaagtaccctgttgccatcaaaatcttc
aagaggccactgaccaccgacccgtcgaaggtgagagacatctttgagaaggagattcag
accctgaagaagtttgagtctccaaacatcctgcgcatgtatgggatctgcattgaggag
aaagatgggagcccctgcttctccatcgtcatggaatactgtaagcatgggacgctgcgg
gacgtgctgaccaagcaacagcatctctcctgggaggtccgcattcggatggccctggga
gctgccagaggcctttacaggttgcaccagacggaggagaagtcccgactccatggctgc
atctgcagtagcaagttcctggtggccggggattactgtgtgaagctgtcgggatttgag
ctgtgtgaaacagagtcatccatcaagaggaaagccaagaagaactggaaacaagtttct
atgttggcttacattgcccccgagaacctgaaagacatcaactacccctacaagaggccc
tgtgaaatatacagcttcgggattgtgctgtgggagattgcaacctccaaaatcccattt
gaaggctgcactccccaggagatcatggagaaaatctgcaatgaccattaccaggcacct
gttggtgaagattgtcctgaagacctgcggaaagtcattgaccagtgccgggcctttgac
ccttcccaacgcccttctgctgaggagattgtggactcactggctgacctggagaaaagc
agaaaccaaggaagttaa
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