Harpia harpyja (harpy eagle): 128150912
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Entry
128150912 CDS
T10541
Symbol
TPMT
Name
(RefSeq) thiopurine S-methyltransferase isoform X1
KO
K00569
thiopurine S-methyltransferase [EC:
2.1.1.67
]
Organism
hhar Harpia harpyja (harpy eagle)
Pathway
hhar00983
Drug metabolism - other enzymes
Brite
Enzymes [BR:
hhar01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.67 thiopurine S-methyltransferase
128150912 (TPMT)
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Gene cluster
GFIT
Motif
Pfam:
TPMT
Methyltransf_25
Methyltransf_11
Motif
Other DBs
NCBI-GeneID:
128150912
NCBI-ProteinID:
XP_052663680
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Position
1:7298072..7342174
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AA seq
244 aa
AA seq
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MERSADGVLEGSDIGSQKDRVVTEEEWLQKWETGNIGFHKEQGHPLFQKYLDVLLNGRSG
LRLFFPLCGKAVEMKWLADMGHSVVGVEVSEQALKEFFAEHNLPYCEEPVPEISGAKKLQ
SASGNISLYCCSIYDLSSSIVGKFDGVWDRGALVAVNPCDRQRYVSLMITLMEKNSSYLV
VTVSYDPNKHKGPPFYVPESEIKSLFGNHCEIKCLQKVDDFSDRHRQWGLDYFLEVLYVL
KFVA
NT seq
735 nt
NT seq
+upstream
nt +downstream
nt
atggagcgctcggcagatggggtgctggaaggctctgatattgggtcacagaaagacaga
gtggtgaccgaggaggaatggctgcaaaaatgggaaacgggtaacatcgggtttcacaag
gaacaagggcatccgctcttccagaagtatctggatgttcttttaaatggcaggagtgga
ctgaggctatttttcccactttgtggtaaagcagtagagatgaaatggctggcggatatg
ggacacagcgtggttggtgtggaagtcagtgagcaagcactgaaggaattttttgcagaa
cacaatctgccttattgcgaggaaccagtcccggagatttcaggagcaaaaaagttgcag
agtgcctctgggaacatttctctgtactgctgcagtatttatgatttgtccagctcaata
gttggcaagtttgatggggtttgggacagaggagctctagtagctgtgaatccatgcgac
agacaacgctatgtcagtttgatgatcaccctaatggagaaaaattcttcttatctcgtc
gttacggtttcatatgatccaaacaaacacaaaggcccaccgttttatgttcctgaatct
gaaattaaaagcttgtttggcaaccactgtgagattaagtgtcttcaaaaagttgatgac
ttctcagacagacacagacaatggggactagattattttctggaggtgctatatgtacta
aagtttgtagcttga
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