Hyaena hyaena (striped hyena): 120220675 Help Entry 120220675         CDS       T07257                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism hhv  Hyaena hyaena (striped hyena) Pathway hhv01524   Platinum drug resistance hhv04115   p53 signaling pathway hhv04210   Apoptosis hhv04215   Apoptosis - multiple species hhv04217   Necroptosis hhv04620   Toll-like receptor signaling pathway hhv04621   NOD-like receptor signaling pathway hhv04622   RIG-I-like receptor signaling pathway hhv04623   Cytosolic DNA-sensing pathway hhv04625   C-type lectin receptor signaling pathway hhv04657   IL-17 signaling pathway hhv04668   TNF signaling pathway hhv04932   Non-alcoholic fatty liver disease hhv04936   Alcoholic liver disease hhv05010   Alzheimer disease hhv05016   Huntington disease hhv05022   Pathways of neurodegeneration - multiple diseases hhv05132   Salmonella infection hhv05134   Legionellosis hhv05142   Chagas disease hhv05145   Toxoplasmosis hhv05152   Tuberculosis hhv05160   Hepatitis C hhv05161   Hepatitis B hhv05162   Measles hhv05163   Human cytomegalovirus infection hhv05164   Influenza A hhv05165   Human papillomavirus infection hhv05167   Kaposi sarcoma-associated herpesvirus infection hhv05168   Herpes simplex virus 1 infection hhv05169   Epstein-Barr virus infection hhv05170   Human immunodeficiency virus 1 infection hhv05200   Pathways in cancer hhv05203   Viral carcinogenesis hhv05416   Viral myocarditis hhv05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:hhv00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     120220675 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     120220675 (CASP8)    04215 Apoptosis - multiple species     120220675 (CASP8)    04217 Necroptosis     120220675 (CASP8)    04115 p53 signaling pathway     120220675 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     120220675 (CASP8)    04621 NOD-like receptor signaling pathway     120220675 (CASP8)    04622 RIG-I-like receptor signaling pathway     120220675 (CASP8)    04623 Cytosolic DNA-sensing pathway     120220675 (CASP8)    04625 C-type lectin receptor signaling pathway     120220675 (CASP8)    04657 IL-17 signaling pathway     120220675 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     120220675 (CASP8)    05203 Viral carcinogenesis     120220675 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     120220675 (CASP8)    05161 Hepatitis B     120220675 (CASP8)    05160 Hepatitis C     120220675 (CASP8)    05164 Influenza A     120220675 (CASP8)    05162 Measles     120220675 (CASP8)    05168 Herpes simplex virus 1 infection     120220675 (CASP8)    05163 Human cytomegalovirus infection     120220675 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     120220675 (CASP8)    05169 Epstein-Barr virus infection     120220675 (CASP8)    05165 Human papillomavirus infection     120220675 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     120220675 (CASP8)    05134 Legionellosis     120220675 (CASP8)    05152 Tuberculosis     120220675 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     120220675 (CASP8)    05142 Chagas disease     120220675 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     120220675 (CASP8)    05016 Huntington disease     120220675 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     120220675 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     120220675 (CASP8)    05416 Viral myocarditis     120220675 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     120220675 (CASP8)    04932 Non-alcoholic fatty liver disease     120220675 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     120220675 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:hhv01002]     120220675 (CASP8) Enzymes [BR:hhv01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      120220675 (CASP8) Peptidases and inhibitors [BR:hhv01002]  Cysteine peptidases   Family C14: caspase family    120220675 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED Motif Other DBs NCBI-GeneID:  120220675 NCBI-ProteinID:  XP_039073722 LinkDB All DBs Position Unknown AA seq 479 aa AA seqDB search MNFNKCLYNIGEWLGSDDLASLKFLSLDYIPQKKQEPIKDALMLFQRLQEKRMLEESNLS FLKELLFRINRLDLLFKYLHTSKEEMEQELQTPGRAQISPYRVMLFQISEDISKLELRSF KFLLSQDISKCKVDDDMNLLDIFIEMEKRVILGERNLDTLKRICDQINKSLLKKITDYEE LSREGRPSLQRSQDEFSNGVESLEMMALLDSPQEQDSESQTSDKVYRMKSKPRGYCLIFN NYDFSRARKDVPKLQNIKDRNGTEFDAEALSKTFSELHFEIVNFKDSTAKTICEVLKTYQ RMDHNNKDCFICCILSHGDKGIIYGSDGQEAPIYELTSYFTGSKCPSLAGKPKIFFIQAC QGDNFQRGIAVETDSKQKEAYLEIDSSLHKSYIPDEADFLLGMATVNNCVSYRNPMEGTW YIQSLCQSLRERCPRGEDILTILTEVNFEVSNKDDKKNMGKQMPQPTFTLRKKLFFPIN NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atgaatttcaataaatgtctctataatattggggaatggctaggcagcgatgacctggcc tccctcaaattcctgagcctggactacatcccacaaaagaagcaagaacccatcaaagat gccttgatgttattccagagactccaggaaaagagaatgttagaggaaagcaacctgtcc ttcttgaaggagctgcttttccgaattaatagactggacctgctattcaaatacctgcac accagcaaggaagagatggagcaggagcttcagacaccaggcagagctcagatctctccc tacagggtcatgctttttcaaatttcagaagatataagcaaattggaattgaggtcgttt aagtttcttttgagccaggacatctccaaatgtaaagtggatgatgatatgaacttgctt gatattttcatagagatggaaaagagggtcatcctaggggaaagaaatttggacactctg aaaagaatctgtgaccaaatcaacaaaagcctgctgaagaaaatcaccgattatgaagaa ttgagcagagagggaagaccgagccttcaaagaagtcaagatgaattttcaaatggggtg gagtccctggaaatgatggcattgttggactctccacaagaacaggacagtgagtcacag acatcggacaaagtttaccgaatgaaaagcaaacctcgaggatattgtttgatctttaac aattatgattttagcagagcacggaaggatgtgcccaaacttcagaacattaaggatagg aacggaacagaatttgacgcagaggctttgagtaagacctttagtgagcttcattttgag attgtgaatttcaaagactctacagcaaagacaatctgtgaggttctgaaaacctaccaa agaatggaccataataacaaggattgcttcatctgctgcatcctctcccatggagacaag ggcatcatttatggctctgatgggcaggaagcccccatttatgagctgacttcttacttc actggttcaaagtgcccttcccttgcagggaagcccaaaatcttttttattcaggcttgt caaggggataacttccagagaggtatagctgttgagactgactctaaacagaaggaagcc tacttagaaatagactcatcacttcataagagctatattccagatgaagctgactttctg ctggggatggccactgtgaacaactgtgtttcctaccgaaaccccatggaggggacctgg tatatccagtcactttgccagagcctaagagaaagatgtcctaggggtgaagatatcctc accatccttaccgaggtgaactttgaagtgagcaataaggatgacaagaaaaacatgggg aaacaaatgccccaacctactttcacactgaggaaaaaactcttcttccctattaattga

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