Hyaena hyaena (striped hyena): 120228300 Help Entry 120228300         CDS       T07257                                  Symbol FASN Name (RefSeq) fatty acid synthase   KO K00665   fatty acid synthase, animal type [EC:2.3.1.85] Organism hhv  Hyaena hyaena (striped hyena) Pathway hhv00061   Fatty acid biosynthesis hhv01100   Metabolic pathways hhv01212   Fatty acid metabolism hhv04152   AMPK signaling pathway hhv04910   Insulin signaling pathway hhv04936   Alcoholic liver disease Module hhv_M00082   Fatty acid biosynthesis, initiation hhv_M00083   Fatty acid biosynthesis, elongation Brite KEGG Orthology (KO) [BR:hhv00001]  09100 Metabolism   09103 Lipid metabolism    00061 Fatty acid biosynthesis     120228300 (FASN)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     120228300 (FASN)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     120228300 (FASN)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     120228300 (FASN)  09180 Brite Hierarchies   09181 Protein families: metabolism    01004 Lipid biosynthesis proteins [BR:hhv01004]     120228300 (FASN)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hhv04147]     120228300 (FASN) Enzymes [BR:hhv01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.85  fatty-acid synthase system      120228300 (FASN) Lipid biosynthesis proteins [BR:hhv01004]  Fatty acid synthase   Animal type    120228300 (FASN) Exosome [BR:hhv04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    120228300 (FASN)   Exosomal proteins of breast milk    120228300 (FASN)   Exosomal proteins of colorectal cancer cells    120228300 (FASN)   Exosomal proteins of bladder cancer cells    120228300 (FASN) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Acyl_transf_1 ketoacyl-synt Thioesterase KR Ketoacyl-synt_C KAsynt_C_assoc FAS_pseudo-KR ADH_zinc_N_2 ADH_zinc_N PKS_DH_N PP-binding adh_short Methyltransf_12 Methyltransf_23 PS-DH Methyltransf_31 DUF7080 Thiolase_N Methyltransf_11 AlaDh_PNT_C Motif Other DBs NCBI-GeneID:  120228300 NCBI-ProteinID:  XP_039082547 LinkDB All DBs Position Unknown AA seq 2515 aa AA seqDB search MEEVVIAGMSGKLPESENLEEFWANLIGGVDMVTDDDRRWKAGLYGLPKRTGKLKDLSKF DTSFFGVHPKQAHTMDPQLRLLLEVAYEAILDGGINPASLRGTHTGVWVGVSGSEASEAL SRDPENLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDSACSSSLLALQSAYQAIRNGEC PAAIVGGINILLKPNTSVQFMKLGMLSPEGCCKSFDESGNGYCRSEAVVAVLLTKKSLAR RVYATILNAGTNTDGCKEQGVTFPSGDVQEQLIRSLYEPAGLDPESLEYIEAHGTGTKVG DPQELNSITRALCATRRDPLLIGSTKSNMGHPEPASGLAALAKVLLCLEHGLWAPNLHFH SPNPEIPALLDGRLQVVRQPLPIRGGNVGINSFGFGGSNVHVVLQPNLRPPPAPAPHAAL PRLMLASGRTPEAVQCLLEQGQRHSQDLGLLSMLNDIAASPPTAMSCRGYTVLGGKGHGQ EVQHVPAGERPLWFICSGMGTQWRGMGLSLMRLGSFRDSILRSDKAVRPLGLQVSELLLT TDEAAFDDNVYAFVSLTAIQIALIDLLTSVGLRPDGIIGHSLGEVACGYADGCLSQEEAI LAAYWRGQCIKEANIPPGAMAAVGLSWEECKQRCPAGVVPACHNSEDTVTISGPQAEVAA FVAELKQEGVFAKEVRTGGIAFHSYFMDSIAPTLLQELKKVIREPRPRSARWLSTSIPEA QWQGSLARTFSAEYNVNNLVSPVLFQEALWHVPANAVVVEIAPHALLQAVLKRGLKPSCA ILPLMKKDQSDNLEFFLSSVGKLHLLGFSVNPNGLFPPVEFPVPRGTPLISPHIKWDHSQ TWDVPTADDFPSGPHSSPATICNIDTSPESPDHYLVDHCIDGRILFPAAGYLCLVWKTLA SAFGQIMEQLPVVFEDVTVHQATILPNTGTVSLEVQLLQASRSFEVSDNGSLIVSGKVYQ WEDPDTKLFDRQDSLYRTDPTATFHLSQGDVYKELRLCGYDYGPHFQGILEANLEGTAGR LLWNGNWVTFLDTMLQMSILSMAQHTLRLPTRITSIHIDPATHLRRMYSLQDKAQAVDVV VSSCLHSTVAGGILLSGLHAEVAPRRQQEQFVPILEKFCFTPYTEQGLLAGDPALQEALQ MCRGLALALQTRVAQQGLKMAVPGLDGAPAPAPQEPPQQGLPRLLAAACQLQLNGSLPLE LGQLLKQQRPLLQDDPLLTGLLDSPALKACVDTALENTTSLKMKVVEVLAGDGHLYSRIP ALLNTQPMLQLDYIATDRHTQALEAVQATLQEHGIAQSQWDPLGSAPSHLGMADLLVCNC AVASLGDPATAIGNMRAALKEGGFLLLHVLLKGHPLGETVAFLTCPEPQRGQQSLLSQDQ WESLLARASLCLVAQKRSFYGSVLFLCRRPLLRDSPVFLPVEDTTFQWVDSLKNVLEDSS LRPVWLTAVSGVTSGVVGLVNCLRKEPSRHRIRCILVSNLSSKVHTPSLDPGSSELQKVL QGDLVMNVYRDGAWGSFRHFPLERGLPEEQTEYAFVNVLTRGDLSSIRWVCSSLRHPRLT SPGVQLCSVYYASLNFRDIMLATGKLSADAIPGKRGVHDCVLGMEFSGRDASGRRVMGLV PAEGLATSVLLSQDFLWEVPSSWTLEEAASVPVVYTTAYYSLVVRGRIQPGETVLIHSGS GGVGQAAITIALSLGCRVFTTVGSAEKRAYLQARFPQLSATCFANSRDTSFEQHVLRHTA GKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHLLGMAVFLKNVTFHGILLD SLLDEVNARWQEVAALLKAGIRDGVVQPLKCTVFPKDQVEDAFRFMAQGKHIGKVVVQVR QEEPEAVLREPSPTLMTAVSRTFCSAHKSYVITGGLGGFGLELAQWLVLRGARKLVLTSR SGIRTGYQAKQVREWRREGVQVLVSTSNASSLDGAQRLIDEATQLGPVGGVFNLAVVLKD AMLENQTPELFQDVNKPKFSGTVNLDRVTRAACSELDYFVAFSSVSCGRGNAGQANYGFA NSTMERVCEKRQHDGLPGLAIQWGAIGDVGLIMEGSGSNDVVIGGTLPQRIASCLEVLDL FLNQPHPVLSSFVLAEKATSPSDGTHQQDLMKAVAHILGIRDLATVNLDSSLADLGLDSL MGVEVRQMLERELDLVMSMRDIRHLTLRKLQELSLKTSTADKLAAPAPKEDSPASQQAQP SLSTLLVNPEGPTLTQLNSVQSSERPLFLVHPIEGSITVFRSLASKLSIPTYGLQCTRAA PLDSIQSLAAYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAAQQSPAPTHNSLFL FDGSHSYVLAYTQSYRAKLTPGCEAEAEAEAMFFFVQQFINVEHSRVLEALLPLKGLEER VAATVDLILRSHAGLDRRELSFAAHSFYHKLRAAEQYMPRATYHGNVTLLRAKTGSVYGE GLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESILSIIHSSLAEPRVSVREG NT seq 7548 nt NT seq  +upstreamnt  +downstreamnt atggaggaggttgtgattgctggcatgtctgggaagctgcccgagtcggagaacttggag gagttctgggccaacctcatcggtggcgtggacatggtaacagatgatgacaggaggtgg aaggcaggactctacggcctgcccaagcggaccggcaagctgaaggacttgtccaagttc gacacctccttcttcggggtccacccaaagcaggctcacacgatggacccccaactgcgc ttgctactggaggtcgcctacgaggccatcctggatggaggcatcaacccagcctccctg cgagggacacacacaggcgtctgggtgggtgtgagcggctcagaggcctcagaggctctg agccgagaccccgagaatctcctgggctacagcatggtgggctgccagcgggctatgatg gccaaccgtctttcctttttctttgattttaaaggacccagcatcgctctggactcagcc tgctcctccagcctgctggcgcttcagagcgcctatcaggccatccgcaacggggagtgc ccggcggccatcgtgggcggcatcaacatcttactcaagcccaacacctccgtgcagttc atgaagctcggcatgctgagtcccgaaggctgctgcaagtccttcgacgagtccgggaac ggctactgccgctcagaggcggtggtggccgtcttgctgaccaagaagtccctggcccgg cgtgtgtacgccaccatcctcaatgccggcaccaacacagacggctgcaaggagcaaggt gtgaccttcccctctggggacgtgcaggaacagctcatccgctccttgtacgagccagcc gggctggacccagagtctcttgagtatatcgaagcccacggcacgggcaccaaggtgggg gacccccaggagctgaacagtatcacccgagccctgtgtgccacccgccgggaccccctg ctgatcgggtccaccaagtcaaacatggggcaccccgagcctgcctcggggctcgcggct ctggccaaggtgctgctgtgcctggagcacgggctctgggcccccaacctgcacttccac agcccgaaccctgagatccccgcgcttctggacggacggctgcaggtggtgcgccagccc ctgcccatccgcggaggcaacgtgggcatcaattcctttggcttcggaggctccaacgtg cacgtcgtcctccagcccaacctgcggccgcccccggcgcctgccccgcacgccgccctg ccccgtctgatgctggccagcgggcgcacccctgaggccgtgcagtgcctgctcgaacag ggccagcggcacagccaggacctaggcctcctgagcatgctcaacgacatcgcagccagc ccccccaccgccatgtcctgccgaggctacaccgtgctgggcggcaagggccacgggcag gaggtgcagcacgtgccggctggcgagcggcccctctggttcatctgctccgggatgggc acgcagtggcgcgggatgggcttgagcctcatgcgcctgggcagcttccgagactccatc ctgcgctccgacaaggccgtgaggcccctgggcctgcaggtgtccgagctgctgctgacc acggacgaggccgccttcgacgacaacgtctacgccttcgtgagcctcactgccatccag attgccctcatagacttgctgacctcggtgggtctgcggcctgacggaatcatcgggcac tccctgggcgaggtggcctgcggctacgcagacggctgcctctcgcaggaggaggccatc ctcgctgcctactggaggggccagtgcatcaaggaagccaacatcccgccaggggccatg gcggccgtgggcttgtcctgggaggagtgtaagcagcgctgccctgctggcgtcgtgccc gcctgccacaactccgaggacaccgtgaccatctcaggaccgcaggcggaggtggccgcg ttcgtggcagagctgaagcaggaaggtgtgtttgccaaggaggtgcggacgggcggcata gccttccactcctacttcatggactccatcgcccccacgctgctgcaggagctcaagaag gtgatccgggagccgcggccccgctcggcacgctggctcagcacatccatccctgaggcc cagtggcagggcagcctggcccgcacgttctcggcagagtataatgtcaacaacctggtt agccccgtgctgttccaggaggcgctgtggcacgtgcccgccaacgccgtggtggtggag atcgccccccacgccctgctgcaggccgttctcaagagaggcctcaagcccagctgcgcc atccttcccctgatgaagaaggaccagagtgacaacctggagttcttcctcagcagcgtg ggcaagttgcacctgttaggcttcagcgtcaaccccaacggcctgtttccacctgtggag tttccagttccccgggggacccctctcatctcccctcacatcaagtgggaccatagtcag acctgggacgtgcccaccgccgatgacttccccagcggccctcacagctcccctgccacc atctgcaacattgacaccagccccgagtcccctgaccactacctggtggaccactgcatc gacggccgcatcctcttcccggccgccggctacctgtgcctggtctggaagactctggca agtgcctttggccaaatcatggagcagctgcccgtggtgtttgaggacgtgacggtgcat caggctaccatcctgcccaataccgggaccgtgtccctggaagtgcagcttctacaggct tcccgaagcttcgaggtgtctgacaacggcagcctgatagtgagcgggaaggtttaccag tgggaggaccccgacaccaagctcttcgacagacaggacagcctgtaccgcacggacccc acggctacgttccacctgagccagggggacgtgtacaaagagctgcgtctgtgcggctat gactacggccctcatttccagggcatcctcgaggccaaccttgaaggcaccgcgggccgg ctgctgtggaacggcaattgggtgacgttcctggacaccatgctgcagatgtccatcctg agcatggcccagcacaccctacgcctgcccacacgcatcacctccatccacatcgacccc gccacccacctgcgcaggatgtactcgctgcaggacaaggcccaagcggtcgacgtggtg gtgagcagctgtctgcacagcacggtggccggcggcatcctcctgtcgggcctccacgcc gaggtggccccgaggcggcagcaggagcagttcgtacccatcctggagaagttctgcttc acgccgtacacagagcaggggctcctcgctggagacccagccctgcaggaggcgctacag atgtgcagagggctggcactggcactgcagactagggtggcccagcaggggctgaagatg gcggtacctgggctggacggggccccggccccggccccccaggagccaccgcagcaaggc ctgccccgcctgctggcggctgcctgccagctgcagctcaatgggagcctcccactggag ctgggccagctgctgaagcagcagcgccccctgctgcaggacgaccccctgctcaccggc ctcctcgactccccggcgctcaaggcctgcgtggacaccgccctggagaacacgaccagc ctcaagatgaaggttgtggaggtgctggctggcgacggccacctatattcccgcatccca gcgctgcttaacacccagcccatgctgcagctggactacatagccacggaccgccacact caggccctggaggctgtccaggccacgctgcaggagcacggcatagcccagagccagtgg gaccccttgggctccgcccccagccacctgggcatggctgatctccttgtgtgtaactgt gccgtggccagcctcggtgatccggccacggccatcggcaacatgcgggccgctctcaag gagggtggcttcctacttctgcacgtcctgctcaaaggacaccccctcggagagacggtc gccttcctcacgtgccctgagccgcaacgaggccagcagagcctcctcagccaggaccag tgggagagtctgcttgccagggcgtccctgtgcctagtggcccagaagaggtccttctac ggttctgtgctcttcctgtgccgccggccgctcctgcgggacagccctgtcttcctgcct gtggaggacaccaccttccagtgggtagactccctgaagaacgttctggaagactcctcc ctccggcccgtgtggctgaccgctgtcagtggggtcacctcaggcgtcgtgggcttggtg aactgcctccgcaaggagcccagcaggcaccggatccggtgcatcctggtgtccaacctc agcagcaaggttcacacccccagtttggaccctggctcctcagagctgcagaaggtgctg cagggggaccttgtgatgaacgtctaccgagacggggcctgggggtccttccgccatttc ccactggagcgtggcctgccggaggagcaaaccgagtacgccttcgtgaacgtcctcacc cggggggacctctcctccatccgctgggtctgctcgtctctgcggcacccccggctcacc agccctggcgtccagctctgttctgtctactatgcttcccttaacttccgagatatcatg ctggccacaggcaagctctccgctgatgccatcccagggaaacggggcgtccacgactgt gtgctgggcatggagttctctggccgagacgccagcggcaggcgtgtcatggggctggtg cccgctgaaggcctggctacctctgtcctgctctctcaggacttcctttgggaggtgccc tccagctggaccctagaggaggcagcttcggtgcctgtggtctacaccaccgcctactac tcgctggtggtgcgggggcgcatacagcctggggagacggtgctcatccactcgggctca ggcggcgtgggccaggccgccatcaccatcgcactcagtctgggctgccgcgtcttcacg actgtggggtcggccgagaagcgggcgtacctccaggccaggttcccccagctcagcgcc acctgctttgccaactcccgggacacatcttttgaacagcacgtgctgcggcacacggca gggaagggtgtggacctggtcttgaattctctggcggaagaaaagctgcaggccagcgtg cggtgcctggcccagcacggccggttcctggaaatcggcaaattcgacctttccaacaat cacctgctgggcatggccgttttcctgaagaacgtgaccttccacgggatcctgctggac tcgctcctggacgaggtcaatgccaggtggcaggaggtggcggcgctgctgaaagcaggc atccgggacggcgtggtgcagcccctcaagtgcaccgtcttccccaaggaccaggtggag gacgcattccgcttcatggcccaagggaagcatatcgggaaggtggtcgtccaggtgcgc caggaggagccggaggcggtgctgcgggagccgagtcccaccctgatgaccgccgtgtcc aggaccttctgctcggcccacaagagttacgtcatcaccgggggcctgggcggcttcggc ctggagctggcccagtggcttgtgctgcgaggggcccggaagctcgtgctgacctctcgc tccggaatccgcacaggctaccaggccaagcaggtccgggagtggaggcgtgagggcgtg caggtcctggtgtccaccagcaacgccagttcgctggatggggcccagagactaatcgat gaggccacacagctgggccccgtgggaggcgtcttcaacctggccgtggtcctgaaagat gccatgctggagaaccaaaccccggagctcttccaggacgtcaacaagcccaagttcagc ggcactgtgaaccttgacagggtgacccgagctgcgtgctccgagctggactacttcgtg gctttctcctccgtgagctgcgggcgtggcaatgctggccaggccaactacggcttcgcc aactccaccatggagcgtgtgtgtgagaagcgccagcatgatggcctcccgggcctcgcc attcagtggggcgccatcggcgacgtaggcctcatcatggagggttcaggttccaatgac gtggtcatcggtggaacgctgccccagcggatcgcctcctgcctggaggtgctggacctc ttcctgaaccagccccaccccgtcttgagcagcttcgtgctggccgagaaggccaccagc cccagtgacggcactcaccagcaggatctgatgaaggccgtggcccacatcctgggcatc cgagacttggccaccgtcaacctggacagctccctggcggacttgggcctggactcgctc atgggtgtggaggtgcgccagatgctggagcgggagctcgacctggtgatgtccatgagg gacatccggcatctgacgctgcggaagctacaggaactctccttgaagaccagcacagct gacaagctggcagcccccgcgcccaaggaagacagtcctgccagccagcaggcccagccg agcctgagcaccctgctggtgaatcctgagggcccgaccttgacgcagctcaactcggtg cagagctcggagcgccccctgttcctggtgcatcccatcgaaggctccatcactgtgttc cgcagcctggcgtccaagctcagcatccccacctacggcttacagtgcactcgagctgcg cctctggacagcatccagagtctggccgcctactacatcgagtgcatcaggcaggtgcag ccggaggggccctaccgcatcgctggctattcctacggggcctgcgtggccttcgagatg tgctcgcagctacaggccgcacagcagagccctgcccccacacataacagcctcttcctg ttcgatggctcacactcctacgtgctggcctacacgcagagttaccgcgcaaagctgacc cccggctgtgaggccgaggccgaggccgaggccatgttcttctttgtgcagcagttcatc aacgtggagcacagcagggtgctggaggcgctgctgccccttaagggcctcgaggagcgc gtggcggccaccgtggacctgatcctgcgcagccacgcaggcctggaccgccgcgagctg agcttcgccgctcattccttctaccacaagctgcgagcagccgagcagtacatgccgcgg gccacctaccacggcaacgtgacgctgctgcgcgccaagactggcagcgtgtacggtgag ggcctgggtgccgactacaacctgtcccaggtgtgcgacggcaaggtgtccgtgcacgtg attgagggcgaccaccgcacgctgctagagggcagcggcctggagtccatcctcagcatc atccacagctccctggctgagccacgtgtcagcgtccgggagggctag

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