Hyaena hyaena (striped hyena): 120239234 Help Entry 120239234         CDS       T07257                                  Symbol JAK3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism hhv  Hyaena hyaena (striped hyena) Pathway hhv04062   Chemokine signaling pathway hhv04151   PI3K-Akt signaling pathway hhv04217   Necroptosis hhv04550   Signaling pathways regulating pluripotency of stem cells hhv04630   JAK-STAT signaling pathway hhv04658   Th1 and Th2 cell differentiation hhv04659   Th17 cell differentiation hhv05161   Hepatitis B hhv05162   Measles hhv05166   Human T-cell leukemia virus 1 infection hhv05169   Epstein-Barr virus infection hhv05200   Pathways in cancer hhv05203   Viral carcinogenesis hhv05223   Non-small cell lung cancer hhv05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:hhv00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     120239234 (JAK3)    04151 PI3K-Akt signaling pathway     120239234 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     120239234 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     120239234 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     120239234 (JAK3)    04659 Th17 cell differentiation     120239234 (JAK3)    04062 Chemokine signaling pathway     120239234 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     120239234 (JAK3)    05203 Viral carcinogenesis     120239234 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     120239234 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     120239234 (JAK3)    05161 Hepatitis B     120239234 (JAK3)    05162 Measles     120239234 (JAK3)    05169 Epstein-Barr virus infection     120239234 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     120239234 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hhv01001]     120239234 (JAK3) Enzymes [BR:hhv01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      120239234 (JAK3) Protein kinases [BR:hhv01001]  Non-receptor tyrosine kinases   JAK family [OT]    120239234 (JAK3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 SH2_1 FERM_F1 Jak1_Phl ABC1 Kdo Kinase-like FERM_C_FAK1 Haspin_kinase Motif Other DBs NCBI-GeneID:  120239234 NCBI-ProteinID:  XP_039099352 LinkDB All DBs Position Unknown AA seq 1104 aa AA seqDB search MAPPSEETPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVWAAKA SGILPVYHSLFALATEDLSYWYPPSHIFSAEDAGTQVLVYRLRFYFPNWFGLEKCHRFGL RKDLASAILDLPVLEHLFAQHRNDLVSGRLAVGLSLKEQGEYLSLAVLDLARMAREQARQ PEELLKTVSYKVCLPPDLRDLIQGLSFVTRKRIRRTVRRALRRVTACQADRHSLMAKYIM DLERLDPARAAETFLVSLPGAAGGQDAPGLLRVAGDSGIHWSPGGDEALQPFCDFPEIVD ISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLTSDSRHFFC KEVAPPRLLQEVAEQCHGPITLDFAINKLKTGGSLPGSYVLRRSPQDFDSFLLTVCVQTP LGPDYKGCLIRCDPMGTFSLAGLGRPHSSLRELLAACWDGGLHVDGVALNLTSCCTPRPK EKSNLIVVRRGCSSLSSSLVQPQAQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR HEAVDGEPRETEVLLKVMDAKHKNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSVMVQ EFVRLGALDTYLRKSGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGA DGNLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS GIPMPISALDPAKKLQFYEERQQLPAPKWMELATLIQQCMVYEPGQRPSFRAIIRDLNSL ITSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR YDPMGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL VMEYLPSGCLRDFLQRHRARLDASRLLLYASQICKGMEYLGSRRCVHRDLAARNILVESE THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL FTYGSKNCSPSAEFLRMMGCERDVPALCCLLELLAEGQRLPAPAACPGEVHELMKLCWAP NPQDRPTFSALGPQLDALWSGSRG NT seq 3315 nt NT seq  +upstreamnt  +downstreamnt atggcgcctcccagtgaggagacgcccctgatccctcagcgttcctgcagcctctcgtct tcagaggctggtgccctgcacgtgctgctgccccctcggggccccggacccccacagcgc ctatccttctcctttggggaccattcagctgaagagctatgtgtctgggctgctaaggcc agtggcatcctgcccgtgtaccactccctctttgctctggccacggaggatctgtcctac tggtaccccccgagccacatcttctccgcggaggatgcaggcacccaagtcctggtctac aggctccgcttttacttccccaactggtttgggttggagaagtgccaccgcttcgggcta cggaaggacctcgccagtgccatccttgacctgcccgtcctggagcacctctttgcccag caccgaaatgacctggtgagcggccgcctcgccgtgggcctcagtctcaaggagcagggt gaatatctcagcctggcggtgctggacctggctcggatggcccgggagcaggcccggcag cctgaggagctgctgaagacggtcagctacaaggtctgcctgccccccgatctgcgcgac ctgatccagggcctgagcttcgtgacgcggaagcgcatccggaggactgtgcgccgggcc ctgcgccgcgtgaccgcctgccaggctgacaggcactcgctcatggccaagtacatcatg gacctggagaggctggacccggccagggccgccgagaccttcctcgtgagcctccccggg gctgctggtggtcaggatgctccggggctgctccgagtggctggtgacagcggcatccac tggagtccaggaggagatgaggccctccagcccttctgtgactttccagaaattgtagac atcagcatcaagcaggctcctcgtgttggcccggctggggagcaccgcctggtcaccgtc accaggacagacaaccagatcctggaggctgagttcccggggctgcctgcggccttgtcc ttcgtggcgctcgtggacggctacttccggctgacctccgactccaggcacttcttctgc aaggaggttgcgccgccgcggctgctgcaggaggtggctgagcagtgccacggtcccatc accttggattttgccatcaacaagctcaagactggaggttcccttcccggctcctatgtt ctccgccgcagcccccaggatttcgacagcttcctcctcactgtctgtgtccagactccc ctgggtcctgattacaagggctgcctcatccggtgcgaccccatgggaaccttctccctg gctggccttggccgtccccacagcagccttcgagagctcttggcagcctgctgggatggt gggctgcatgtggacggggtcgcgctgaacctcacttcctgctgcacccccagacccaaa gaaaagtccaacctgattgtggtgcggagaggttgcagctccctctcatcgtcccttgtc cagccccaagcccaatgccagctgagtcagatgacgtttcacaagatccctgctgacagc ctggagtggcatgagaacctgggtcatgggtccttcaccaagatttaccgaggttgtcgc catgaggctgtggacggggagcccagggagacggaggtgctactcaaagtgatggatgcc aagcacaaaaactgcatggagtcatttctggaagcagcgagtttgatgagccaagtgtca tatcagcatctcgtgttgcttcatggcgtgtgcatggctggagacagtgtcatggtgcaa gaatttgtgcgtctgggagcgctggatacatatctgcgcaagtctggccacctggtgccg gccagctggaaactgcaggtgatcaaacagctggcctatgccctcaactatctggaagac aaaggtctcccccacggcaatgtctcagcccggaaggtgctcttggctcgggagggggct gatgggaacctgcccttcatcaagttgagtgaccctggcgttagccccactgtgctgagc ctggagatgctcactgacaggatcccctgggtggcccccgagtgtctccaagaggcccgg acacttggcttggaagctgacaagtggggttttggtgccacggtctgggaagtgttcagc gggatcccgatgcccatcagtgccctggatcctgccaagaagctccagttttatgaggaa cggcagcaacttcctgcccccaagtggatggagctggccacactgatccaacagtgcatg gtctacgagccaggccagaggccctcattccgcgccatcatccgtgatctgaacagtctc atcacctcagattatgagctcctctcagaccccacgcctggtgccttggcgccccgtgac gggctgtggaatggcgcccagctctatgcgtgccaggaccctacaatttttgaggagaga catctcaagtacatctcacagctgggcaagggcaactttggcagcgtggaactgtgccgc tatgacccaatgggtgacaacacgggcgccctggtggctgtgaagcagcttcagcacagc gggccagaccagcagagggacttccagcgggaaatccagatcctcaaagcgctccacagc gacttcatcgtcaagtaccgcggcgtcagctatggcccgggccgccagagcctgcggctg gtgatggagtacttgcccagcggctgcctgcgcgacttcctgcagcgacaccgcgcgcgc ctcgacgccagccgcctgcttctctacgcctcgcagatctgcaagggcatggagtacctg ggctcccgccgctgcgtgcaccgcgacctggcggctcgtaacatcctggtggagagcgag acgcacgtcaagatcgccgacttcggccttgccaagctgctgccactcgacaaagactac tacgtggtccgcgagcccggccagagccccatcttctggtacgccccagagtccctctcc gacaacatcttctcgcgccagtctgacgtctggagcttcggggtcgtcctgtacgagctt ttcacctacggcagcaagaattgcagcccctcggccgagtttctgcggatgatgggatgt gagcgagatgtccccgccctctgctgcctcctggagctgctggctgagggtcagaggctg cccgcgcctgctgcctgccctggtgaggttcatgagctcatgaagctgtgctgggccccg aacccgcaagaccggccaacattcagtgccctgggcccccagctggatgcactgtggagc ggaagccggggatag

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