Hyaena hyaena (striped hyena): 120242777
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Entry
120242777 CDS
T07257
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv04120
Ubiquitin mediated proteolysis
hhv04144
Endocytosis
hhv04330
Notch signaling pathway
hhv04668
TNF signaling pathway
hhv04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
120242777 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
120242777 (ITCH)
04668 TNF signaling pathway
120242777 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
120242777 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
120242777 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hhv04131
]
120242777 (ITCH)
04121 Ubiquitin system [BR:
hhv04121
]
120242777 (ITCH)
Enzymes [BR:
hhv01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
120242777 (ITCH)
Membrane trafficking [BR:
hhv04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
120242777 (ITCH)
Ubiquitin system [BR:
hhv04121
]
Ubiquitin ligases (E3)
HECT type E3
120242777 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
120242777
NCBI-ProteinID:
XP_039104635
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIFETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLDSEVVTNGETTCSESASQNDDGSRPKDEARTNPNGS
DEPEDSGAGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNINSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagtcacagttgatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttattgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcatcagacactgaaatctgatgttttgttgggaactgcagcatta
gatatctttgaaaccttaaagtcaaacaacatgaaacttgaggaagtagttgtgacctta
cagcttgtaggtgacaaagagccaacagagacaataggagacttgtccgtttgtcttgat
gggctgcagttagactctgaagttgttaccaatggtgaaactacatgttcagaaagtgct
tcacaaaatgatgatggctccagacccaaggatgaagcaagaacaaatccaaatggatca
gatgaacctgaggattcaggggctggtgaaaataggaaggtcaatgggaataactctcca
tcactctcaaatggcggttttaagccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccgtctgccacttctgaaagtgat
ggatccagtacgggctctctgccaccaacaaatataaattcaaatacatctgaaggagca
acatctggattaataattcctcttactatatctggaggctcaggccctaggccattaaat
cctgtacctcaagctcccctaccacctggttgggaacagagagtggaccagcatgggcga
gtttactacgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggagcggcgtgttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacatggcagaggccaacattggaatctgtccggaactatgaacagtggcag
ctccaacgtagtcagcttcaaggagcaatgcagcagtttaaccagagattcatttatggg
aatcaagatttgtttactacatcacaaaataaagaatttgatccccttggtcccctgcca
cctggatgggagaagagaacagacagcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaggaccccagaagtcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagtagatggaattccatattttgtggaccacaataga
agaacaactacctatattgatccccgcactggaaaatctgctctagacaatggaccacag
atagcctacgtacgggacttcaaggcaaaggttcagtatttccggttctggtgtcagcaa
ctggcgatgccacagcacataaagattacagtgacaagaaaaacattatttgaagattcc
tttcagcagataatgagcttcaatccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagagtggttctttcttttgtca
cacgaggtgttgaaccccatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagattaatcctgcttcttatatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgccatggctttgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatattgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctctgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cctaatggtggcaatattcttgtgacagaagaaaataaagaagaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaggaattagaggtcctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcac
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctgcagtttgttacgggaacctgccgattgccagttggagga
tttgctgacctcatggggagcaatggaccacagaaattctgcattgaaaaagttgggaaa
gaaaactggttacccagaagtcatacctgttttaaccgcctggacctgcctccctacaag
agctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaaggatttgga
caagagtaa
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