Haemophilus influenzae R2846 (nontypeable): R2846_0760
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Entry
R2846_0760 CDS
T01980
Symbol
aceE
Name
(GenBank) Pyruvate dehydrogenase, E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
hie
Haemophilus influenzae R2846 (nontypeable)
Pathway
hie00010
Glycolysis / Gluconeogenesis
hie00020
Citrate cycle (TCA cycle)
hie00620
Pyruvate metabolism
hie00785
Lipoic acid metabolism
hie01100
Metabolic pathways
hie01110
Biosynthesis of secondary metabolites
hie01120
Microbial metabolism in diverse environments
hie01200
Carbon metabolism
hie01210
2-Oxocarboxylic acid metabolism
Module
hie_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hie00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
R2846_0760 (aceE)
00020 Citrate cycle (TCA cycle)
R2846_0760 (aceE)
00620 Pyruvate metabolism
R2846_0760 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
R2846_0760 (aceE)
Enzymes [BR:
hie01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
R2846_0760 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ADO96172
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Position
complement(789329..791989)
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AA seq
886 aa
AA seq
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MSEILKNDVDPIETQDWLQSLDSLIREEGVERAQYIVEQVIGQARTSGVSLPTGVTTDYV
NTIPVAEQPAYPGDHAIERRIRSAVRWNAIAMVLRSQKKDLDLGGHISTFQSAATMYEVC
YNHFFKATTEKNGGDLIFFQGHAAPGMYARAFLEGRLTEEQMDNFRQEAFTDGLSSYPHP
KLMPEFWQFSTVSMGLGPVNAIYQARFLKYLDNRGLKDTKDQKVYAFLGDGEMDEIESKG
ALTFAAREKLDNLIFTISCNLQRLDGPVNGNGKIVQELEGLFTGAGWEVIKVLWGSDWDK
LFAKDTSGKLTQLMMEVVDGDYLTFKSKDGAYIREHFFGRYPETAALVADMTDDEIWALR
RGAHDSEKLYAAYVKAQNATKPVVILAHQVKGYKIPEAESKNTAHQSKKMSYESLKGFRD
FFELPLTDEQVEKLEYIKFAEGTPEYEYLHGHRKALNGYVPARRTKFDVEYKVPALEEFK
ALLEEQPRGISTTMAFTRALNILLKDKNIGKTIVPMIADEARTFGMEGLFRQVGIYNPHG
QNYVPSDRDLVAYYREAKDGQVLQEGINELGATASWLAAANSYSVNNQPMIPFFIYYSMF
GFQRVGDLMWAAGDQLARGFMVGGTSGRTTLNGEGLQHEDGHSHIQAGVIPNCVTYDPSF
AFEVAVIMQDGINRMYGEKQEDVFYYMTTLNEVMDQPAMPAGAEEGIRKGLYKFETVEGK
KGKGHVQLLGSGAIMRHVREAAQILANDYGVTADVFSAPSFNELAREGHDAARWNLLHPT
ETQRVPYVAQVLADLPTVASTDYVKGYADQIRAFVPSKHYHVLGTDGFGRSDSRANLREH
FEVDARYVVVAALSQLAKEGTVSNQVVADAIAKFGLNVDRINPLYA
NT seq
2661 nt
NT seq
+upstream
nt +downstream
nt
atgtctgagattttaaaaaatgacgttgatccaatcgaaacacaagattggttgcaatca
ttagattcattaattcgtgaagagggcgttgaacgtgctcaatatatcgttgagcaagtt
attggtcaagcacgcacaagtggtgtttcattgccaacaggggtaaccactgattacgtg
aatactattcctgtggctgagcaacctgcttatccaggtgatcacgccatcgaacgtcgt
attcgttcagcagtacgttggaatgcgatcgcaatggttttacgcagtcagaagaaagat
cttgacttaggtggtcatatttccacttttcaatctgctgcaactatgtatgaagtgtgt
tataaccacttcttcaaagctacaacagagaaaaacggtggcgacttaattttcttccaa
ggccatgcagcacctggtatgtatgcgcgtgctttcttagaaggtcgtttaactgaagaa
caaatggataacttccgtcaagaagcctttaccgacggtttatcttcatatccacaccct
aaattaatgcctgaattttggcaattctctacggtttctatgggattaggccctgtgaac
gccatctatcaagcgcgtttcttaaaatacttagataaccgtggcttaaaagataccaaa
gatcaaaaagtttatgctttcttaggcgatggcgagatggatgaaattgagtctaaagga
gcattaactttcgcagcacgtgaaaaattagataacttaatcttcactattagctgtaac
ttacaacgtttagatggccctgtgaatggtaacggtaaaatcgttcaagaattagaagga
ttatttactggtgcgggctgggaagtgattaaagttttatggggcagcgattgggataaa
ttattcgctaaagatacttcaggtaaattaactcagttaatgatggaagtggttgatggc
gactatttaacctttaaatctaaagatggtgcttatattcgtgaacacttcttcggtcgt
tacccagaaactgcggcattagtagcagatatgaccgatgatgaaatttgggcattacgc
cgtggtgcacacgatagcgaaaaattatatgcagcctatgtaaaagcacaaaatgcaacg
aaaccagttgtaattttagctcatcaagttaaaggttataaaattcctgaagcggaaagt
aaaaataccgctcaccaatctaaaaaaatgtcttacgaaagccttaaaggtttccgtgac
ttctttgaactaccattaaccgatgaacaagtcgaaaaattagaatacattaaatttgct
gaaggcacacctgagtatgaatacttacatggccaccgtaaagcattaaacggttatgtt
cctgctcgtcgtactaaatttgatgttgaatataaagtacctgcattagaagaatttaag
gccttattagaagaacaacctcgtggtatttcaaccactatggcgttcactcgtgcatta
aacatcctattaaaagataaaaatattggtaaaactatcgttccaatgattgcggatgaa
gcgcgtacattcggtatggaaggtttattccgtcaagtaggtatttataacccacatggt
caaaactatgttccttcagatcgtgatttagtggcttactatcgtgaagcaaaagatggt
caagttctacaagaaggtatcaatgaattaggtgcaaccgcatcttggttagccgcagca
aattcatattctgtcaataaccaaccaatgatcccattctttatttattactcaatgttt
ggtttccaacgcgtaggcgatttaatgtgggcagcgggagaccaattagcgcgcggcttt
atggtagggggtacttctggtcgtacaaccttaaatggcgaaggtttacaacacgaagat
ggtcacagccatattcaagctggcgttattcctaattgcgttacttacgatccatcattc
gcatttgaagttgctgttattatgcaagatggtatcaaccgtatgtacggcgaaaaacaa
gaagatgtattctattatatgactacattaaatgaagttatggatcaacctgcaatgcct
gctggtgcggaagaaggtatccgtaaaggtttatataaatttgaaacagtggaaggtaaa
aaaggcaaaggtcacgttcaattgttaggttctggtgcgattatgcgccacgtgcgtgaa
gcagcacaaattcttgcaaatgattatggcgtaaccgctgatgtattctctgccccatct
ttcaatgaattggctcgtgaaggtcacgatgcggcacgttggaacttattacacccaaca
gagacacaacgcgtaccatacgttgctcaagtattagctgatttaccaaccgttgcttca
actgactatgtgaaaggttatgctgatcaaatccgtgcatttgtaccaagtaagcactat
catgtattaggtacagacggtttcggtcgttcagatagccgtgcaaacttacgtgaacac
ttcgaagttgatgcacgttatgttgtggttgctgcactttctcaattagcgaaagaaggt
acagtatctaaccaagtggttgcagatgcgattgcgaaattcggtttgaatgtagatcgt
atcaatccgctttatgcgtaa
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