KEGG   Haemophilus influenzae 723: NTHI723_00720
Entry
NTHI723_00720     CDS       T03722                                 
Symbol
bepE
Name
(GenBank) Efflux pump membrane transporter BepE
  KO
K18138  multidrug efflux pump
Organism
hix  Haemophilus influenzae 723
Pathway
hix01501  beta-Lactam resistance
hix01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:hix00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    NTHI723_00720 (bepE)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    NTHI723_00720 (bepE)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hix02000]
    NTHI723_00720 (bepE)
   01504 Antimicrobial resistance genes [BR:hix01504]
    NTHI723_00720 (bepE)
Transporters [BR:hix02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   NTHI723_00720 (bepE)
Antimicrobial resistance genes [BR:hix01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    NTHI723_00720 (bepE)
SSDB
Motif
Pfam: ACR_tran MMPL SecD_SecF_C
Other DBs
NCBI-ProteinID: AJO91180
UniProt: A0AAJ8WAH6
LinkDB
Position
complement(743631..746711)
AA seq 1026 aa
MKFTDIFIRRPVLAVSISLLMIILGLQAISKLAVREYPKMTTTVITVSTAYPGADANLIQ
AFVTSKLEESIAQADNIDYMSSTSAPSSSTITIKMKLNTDPAGALADVLAKVNAVKSALP
NGIEDPSVSSSSGGSGIMYISFRSKKLDSSQVTDYINRVVKPQFFTIEGVAEVQVFGAAE
YALRIWLDPQKMAAQNLSVTTVMSALSANNVQTAAGNDNGYYVSYRNKVETTTKSVEQLS
NLIISSNGDDLVRLRDIATVELNKESDNSRATANGAESVVLAINPTSTANPLTVAEKIRP
LYESIKTQLPDSMESDILYDRTIAINSSIHEVIKTIGEATLIVLVVILMFIGSFRAILIP
ILAIPISLIGVLMLLQSFNFSINLMTLLALILAIGLVVDDAIVVLENIDRHIKAGETPFR
AAIIGTREIAVPVISMTIALIAVYSPMALMGGITGTLFKEFALTLAGAVFISGVVALTLS
PMMSSKLLKSNAKPTWMEERVEHTLGKVNRVYEYMLDLVMLNRKSMLAFAVVIFSTLPFL
FNSLSSELTPNEDKGAFIAIGNAPSSVNVDYIQNAMQPYMKNVMETPEVSFGMSIAGAPT
SNSSLNIITLKDWKERSRKQSAIMNEINEKAKSIPEVSVSAFNIPEIDTGEQGAPVSIVL
KTAQDYKSLANTAEKFLSAMKASGKFIYTNLDLTYDTAQMTISVDKEKAGTYGITMQQIS
NTLGSFLSGATVTRVDVDGRAYKVISQVKRDDRLSPESFQNYYLTASNGQSVPLSSVISM
KLETQPTSLPRFSQLNSAEISAVPMPGTSSGDAIAWLQQHATDNLPQGYTFDFKSEARQL
VQEGNALAVTFALAVIIIFLVLAIQFESIRDPMVIMISVPLAVSGALVSLNILSFFSIAG
TTLNIYSQVGLITLVGLITKHGILMCEVAKEEQLNYGKTRIEAITHAAKVRLRPILMTTA
AMVAGLIPLLYATGAGAVSRFSIGIVIVAGLSIGTIFTLFVLPVVYSYVATEHKPLPVFD
ENKTTH
NT seq 3081 nt   +upstreamnt  +downstreamnt
atgaaatttaccgatatatttattcgtcgtcctgttttagcagtttcaattagtttgtta
atgattattttagggttgcaagcaatctcgaaattggcagtgcgtgaataccctaaaatg
actactacagtcattacagtgagtaccgcatatccaggggcagatgcgaatttaatccaa
gcatttgttacgtcaaaattggaagaatctatcgcgcaagccgataatattgattatatg
tcttcgactagtgcgcctagtagttcgactattacaataaaaatgaaattaaataccgat
cctgcaggcgcgttagcagatgtgttagccaaagtgaatgcagtaaagtcagcattacca
aatggtattgaagatcctagtgtatcctcttcttcaggtgggagcggtattatgtatatc
agtttccgatctaaaaaactagattctagtcaggtaactgattacatcaatcgtgtagtc
aaaccacagttttttaccattgagggtgttgccgaagtacaggtatttggtgcagctgaa
tatgcattacgtatttggctagatccacaaaaaatggcagctcaaaatctttctgtgaca
acagtgatgtctgcgctttctgctaataatgtacaaacggctgcggggaacgataatggc
tattatgtgagttatcgtaataaagtggagactacaacgaaatcagtggaacaactcagc
aacttaattatttcatcaaatggcgatgatttagtgcgtttgcgtgatattgcaaccgtt
gaattaaataaagaaagtgataattcgcgtgctacggcaaatggcgcagagtccgttgtg
ttagccatcaatccaacctcgacagcaaaccctttgactgtcgcagaaaaaattcgccct
ttatatgaaagtataaaaacacaactgccagacagtatggaaagcgatattctttatgac
cgcactattgccattaatagttctattcacgaggtcataaaaactattggtgaagccact
ttgatcgttttagtagtaattttaatgtttatcggttcgttccgtgccattttaattcca
atattggctattccaatttctcttattggcgtattaatgctgctacaaagtttcaacttt
tctattaatttaatgaccttgcttgctttaattcttgccataggtttagtcgtagatgat
gctattgtggtgctggagaatattgatcgtcatattaaagcgggagaaactccattccga
gcggcgattattggtacgcgtgaaattgcagtccctgttatttctatgactattgcgttg
atcgcggtttattcgccaatggctttaatgggcggcattaccggcacattgtttaaagag
tttgctttaacccttgctggtgcagtatttatttctggtgttgtggcattaacgttatcg
ccaatgatgagtagtaagttactcaaatccaatgctaaaccaacatggatggaagaacgc
gtagaacataccttaggtaaagtaaatcgtgtttacgaatacatgcttgatctcgttatg
ctcaatcgtaaatcaatgctggcttttgcggtcgtgattttctcaacgctcccatttttg
tttaattcactttctagtgaattaacgccaaatgaagataaaggcgcatttattgcaatt
ggtaacgcgccatctagcgtaaatgtggattacattcaaaatgcaatgcaaccatatatg
aaaaatgtaatggaaacacccgaagtctcttttggtatgagcattgctggcgcgccaact
tctaatagctcgttaaatatcatcacattgaaagattggaaagaacgttcacgtaaacaa
tctgcaataatgaatgaaattaatgaaaaagcaaaatcaattccagaagtgtcagtatca
gcatttaacattcctgaaattgatacaggggaacaaggcgctccagtctctattgtattg
aaaactgcacaagattataaatctttggcaaacaccgcagagaaattcctcagtgcgatg
aaagcctctggcaaatttatttatacaaatttagatttgacctatgacacggcgcaaatg
acaatttcagtagataaagagaaagctggtacttatggcatcacgatgcaacaaatcagt
aatactttagggagtttcttatctggtgcgacagttacgcgtgtggatgtggatggacgc
gcttataaagtcatttcgcaggtaaaacgagatgatcgcttatcgccagaaagtttccaa
aattattatttaactgcatctaatggtcaatcagtgccattaagtagtgttattagtatg
aaattagaaactcagccaacatcattaccgcgtttcagtcagttaaattcggctgaaatc
agtgctgtaccaatgccgggtacatcaagtggtgatgccattgcttggcttcaacaacat
gcaacagacaatttaccgcaaggctatacgtttgattttaaatctgaagcacgtcaatta
gtccaagaaggcaacgcattagccgtcacttttgcattggctgttatcatcatattcttg
gtacttgccattcagtttgaatctatacgtgacccaatggtaattatgatttccgtacca
ttagccgtaagtggtgcattggtgagcttaaatattttatccttctttagcatcgcagga
acaacattaaatatctactctcaagttgggttgattactctcgtgggattaatcaccaaa
cacggtatcttaatgtgcgaagtggcaaaagaagaacagctaaactatggtaaaactcgt
attgaggcaatcactcacgcggcaaaagtgcgtttgcgtccaattctaatgacaactgct
gcaatggtagctggcttaattccattactctatgcaacaggtgcaggagcggtatctcgc
tttagtattgggatagtgattgtagcgggattatccattggtactattttcaccttgttc
gtcttgcctgtggtatatagctatgtcgcaactgaacacaaaccattaccggtttttgat
gaaaataaaacaacccactaa

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