Haemophilus influenzae R2866 (nontypeable): R2866_0822
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Entry
R2866_0822 CDS
T01981
Symbol
aceE
Name
(GenBank) Pyruvate dehydrogenase, E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
hiz
Haemophilus influenzae R2866 (nontypeable)
Pathway
hiz00010
Glycolysis / Gluconeogenesis
hiz00020
Citrate cycle (TCA cycle)
hiz00620
Pyruvate metabolism
hiz00785
Lipoic acid metabolism
hiz01100
Metabolic pathways
hiz01110
Biosynthesis of secondary metabolites
hiz01120
Microbial metabolism in diverse environments
hiz01200
Carbon metabolism
hiz01210
2-Oxocarboxylic acid metabolism
Module
hiz_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hiz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
R2866_0822 (aceE)
00020 Citrate cycle (TCA cycle)
R2866_0822 (aceE)
00620 Pyruvate metabolism
R2866_0822 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
R2866_0822 (aceE)
Enzymes [BR:
hiz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
R2866_0822 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ADO80774
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Position
complement(830689..833349)
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AA seq
886 aa
AA seq
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MSEILKNDVDPIETQDWLQSLDSLIREEGVERAQYIVEQVIGQARTSGVSLPTGVTTDYV
NTIPVAEQPAYPGDHAIERRIRSAVRWNAIAMVLRSQKKDLDLGGHISTFQSAATMYEVC
YNHFFKAATEKNGGDLIFFQGHAAPGMYARAFLEGRLTEEQMDNFRQEAFTDGLSSYPHP
KLMPEFWQFSTVSMGLGPVNAIYQARFLKYLDNRGLKDTKDQKVYAFLGDGEMDEIESKG
ALTFAAREKLDNLIFTISCNLQRLDGPVNGNGKIVQELEGLFTGAGWEVIKVLWGSDWDK
LFAKDTSGKLTQLMMEVVDGDYLTFKSKDGAYIREHFFGRYPETAALVADMTDDEIWALR
RGAHDSEKLYAAYAKAQNATKPVVILAHQVKGYKIPEAESKNTAHQSKKMSYESLKGFRD
FFELPLTDEQVEKLEYIKFAEGTPEYEYLHGHRKALNGYVPARRTKFDVEYKVPALEEFK
ALLEEQPRGISTTMAFTRALNILLKDKNIGKTIVPMIADEARTFGMEGLFRQVGIYNPHG
QNYVPSDRDLVAYYREAKDGQVLQEGINELGATASWLAAANSYSVNNQPMIPFFIYYSMF
GFQRVGDMMWAAGDQLARGFMVGGTSGRTTLNGEGLQHEDGHSHIQAGVIPNCVTYDPSF
AFEVAVIMQDGINRMYGEKQEDVFYYMTTLNEVMDQPAMPAGAEEGIRKGLYKFETVEGK
KGKGHVQLLGSGAIMRHVREAAQILANDYGVTSDVFSAPSFNELAREGHDAARWNLLHPT
ETQRVPYVAQVLADLPTVASTDYVKAYADQIRAFVPSKHYHVLGTDGFGRSDSRANLREH
FEVDARYVVVAALSQLAKEGTVSNQVVADAIAKFGLNVDRINPLYA
NT seq
2661 nt
NT seq
+upstream
nt +downstream
nt
atgtctgagattttaaaaaatgacgttgatccaatcgaaacacaagattggttgcaatca
ttagattcattaattcgtgaagagggcgttgagcgtgctcaatatattgttgagcaagtt
attggtcaagcacgtacaagtggtgtttcattgccaacaggagttaccactgattacgtg
aatactattcctgtggctgagcaacctgcttatccaggtgatcacgccatcgaacgtcgt
attcgttcagcagtacgttggaatgcgatcgcgatggttttacgcagtcagaagaaagat
cttgatttaggtgggcatatttccactttccaatctgcagcaacaatgtatgaagtttgc
tacaaccacttttttaaagctgcaacagagaaaaatggcggcgatttaattttcttccaa
ggccatgcagcaccaggtatgtatgcgcgtgctttcttagaaggtcgtttaactgaagaa
caaatggataacttccgtcaagaagcctttaccgacggtttatcttcatatccacaccct
aaattaatgcctgaattctggcaattctctacggtttctatgggtttaggccctgtgaat
gccatctaccaagcgcgtttcttaaaatatctcgataaccgtggtttaaaagataccaaa
gatcaaaaagtttatgcattcttaggcgatggcgagatggatgaaattgagtctaaaggt
gcattaacttttgcggctcgtgagaagttagataacttaatcttcactatcagctgtaac
ttacaacgtttagatggccctgtgaatggtaatggtaaaatcgttcaagagttagaaggg
ctatttactggtgctggctgggaagtgattaaagttttatggggcagcgattgggataaa
ttattcgcgaaagatacttcaggtaaattaactcagttaatgatggaagtcgttgatgga
gattatttaacctttaaatctaaagatggtgcatatattcgtgaacacttcttcggtcgt
tatccagaaactgctgcattagttgctgatatgaccgatgatgaaatctgggcattacgc
cgtggtgcacatgatagcgaaaaattatatgcagcctatgcaaaagcacaaaatgcaacg
aaaccagttgtgattttagcgcatcaagttaaaggttataaaattcctgaagcggaaagt
aaaaataccgctcaccaatctaaaaaaatgtcttacgaaagccttaaaggtttccgtgac
ttctttgaattaccattaaccgatgaacaagtagaaaaattagaatacattaaatttgct
gaaggcacacctgagtatgaatacttacatggtcaccgtaaagcattaaacggttatgtt
cctgctcgtcgtactaaatttgatgttgaatataaagttcctgcattagaagaatttaaa
gcattattagaagaacaacctcgtggtatttcaaccactatggcgtttactcgtgcatta
aacatcttattaaaagataaaaacatcggtaaaactatcgttccaatgattgcggatgaa
gcgcgtactttcggtatggaaggtttattccgtcaagttggtatttataacccacatggt
caaaactatgtaccttcagaccgtgatttagtggcttactatcgtgaagcaaaagatggt
caagtgctacaagaaggtatcaatgaattaggtgcaaccgcatcttggttagcagcagcg
aactcgtactctgtcaataaccaaccgatgattccattcttcatctattactcaatgttt
ggtttccaacgtgtgggcgatatgatgtgggctgcaggcgaccaattagctcgtggcttt
atggtagggggtacttctggtcgtacaaccttaaatggcgaaggcttacaacacgaagac
ggtcacagccatattcaagcgggcgttattcctaattgcgttacttacgatccatcattt
gcatttgaagtcgctgtaattatgcaagacggtatcaaccgtatgtacggcgaaaaacaa
gaagatgtattctattatatgactacattaaatgaagtgatggatcaacctgcaatgcct
gctggtgcggaagaaggtatccgtaaaggtttatataaatttgaaacagtggaaggtaaa
aaaggcaaaggtcacgttcagttattaggttctggtgcgattatgcgtcacgttcgtgaa
gcggcacaaattcttgcaaatgactacggtgtgacttcagatgtattttctgcgccttca
ttcaatgaattagcacgcgaaggtcatgatgcagcacgttggaacttattacacccaaca
gagacacaacgcgtaccatacgttgctcaagtattagctgatttaccaaccgttgcttca
actgactatgttaaagcatacgcagatcaaatccgtgcatttgtaccaagtaagcactat
catgtattaggtacagacggtttcggtcgttcagatagccgtgcaaacttacgtgaacac
ttcgaagttgatgcacgttatgttgtggttgctgcactttctcaattagcgaaagaaggt
acagtatctaaccaagtggttgcagatgcgattgcgaaattcggtttgaatgtagatcgt
atcaatccgctttatgcgtaa
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