Haliaeetus leucocephalus (bald eagle): 104831735
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Entry
104831735 CDS
T08630
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
hle
Haliaeetus leucocephalus (bald eagle)
Pathway
hle00140
Steroid hormone biosynthesis
hle01100
Metabolic pathways
Module
hle_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
hle_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
hle_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
hle00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
104831735
Enzymes [BR:
hle01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
104831735
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
104831735
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Ortholog
Paralog
GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_4
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
NmrA
KR
Ldh_1_N
DUF5406
Motif
Other DBs
NCBI-GeneID:
104831735
NCBI-ProteinID:
XP_010565816
LinkDB
All DBs
Position
Unknown
AA seq
377 aa
AA seq
DB search
MSLAGVSCLVTGAGGFLGQRIVHLLLEEEEALAEIRLLDKAFSNEALGRFGTFQGKTAVK
ILEGDIRDVTFLHRACQGVSVVIHTASIIDTLGLIEKQLLWEVNVTGTQLLLEACVRCNV
QHFIYTSTIEVTGPNCKGDPIFNGDEDTAYESISKSPYAQSKRLAEDSVLKADGQVLNDG
STLMTCALRSMYIFGEGCPFLQGHLDKCLLNKNVYLRFSRKEAFVNPVYVGNIAWAHVQA
AKALQVPQKAKHIRGQFYYISDDTPHMSYADLNYELTRDLGFGIEPRLPMPLTMLYYFSL
LLEIVSFLLRPFVRYIPSTNRHLVTLLNTPFTFSYRKAQKDFGYVPRYTWEEAKQCTAQW
IASMVPQRREYLKSKAA
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atgtccctggctggagtaagctgcctggtgacaggagcaggaggatttcttggtcagagg
attgtccacttgctgttggaagaagaggaggcgctggctgagatccgactgctagacaaa
gcctttagcaatgaagcacttggcagatttggaacgttccagggtaagacagcggtgaaa
atcctggaaggagacatccgagatgtgacattcctgcaccgtgcctgtcagggggtctcc
gtcgtcatccacacggcttccatcattgacaccttgggcctcatagagaagcagctgctc
tgggaagtcaatgtaacaggtactcagctactgctggaggcatgtgtccgttgtaatgtc
cagcacttcatatataccagtaccatagaagtgacaggcccaaactgcaaaggtgaccca
attttcaatggtgatgaagatacagcttatgagagtatatcaaaatctccttacgcccag
agtaagagactggcagaggattctgtgctgaaagcagatggccaggtgctaaacgatggt
agcacgctgatgacctgcgccctgagatccatgtacatttttggagaaggttgcccgttt
cttcaaggtcatctggataagtgtctgttgaacaaaaatgtctacctgcgcttctccagg
aaggaggcttttgtgaaccccgtgtacgtggggaacatcgcctgggcacatgtgcaggca
gccaaagccctgcaagtcccgcagaaagccaagcacatcagggggcagttctactacatc
tcagatgacactccgcatatgagctatgcagatctaaattacgagctgaccagggacctg
gggtttggaatcgagccccggctccccatgcctctgacaatgttgtattacttctcgctg
ctgctggagatcgtgagcttcttgcttcggccctttgtcagatacatcccctccaccaac
cgtcacctggtcactctattgaacaccccattcaccttctcttatagaaaagcacagaag
gattttggctacgtgcctcgctacacgtgggaagaggccaagcagtgcactgctcagtgg
attgcttccatggtcccacagagaagggagtacttgaaaagcaaggctgcctaa
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