KEGG   Hydrogenovibrio marinus: HVMH_0226
Entry
HVMH_0226         CDS       T06677                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
hmar  Hydrogenovibrio marinus
Pathway
hmar00270  Cysteine and methionine metabolism
hmar00450  Selenocompound metabolism
hmar00670  One carbon pool by folate
hmar01100  Metabolic pathways
hmar01110  Biosynthesis of secondary metabolites
hmar01230  Biosynthesis of amino acids
hmar04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:hmar00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    HVMH_0226 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    HVMH_0226 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    HVMH_0226 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    HVMH_0226 (metH)
   04980 Cobalamin transport and metabolism
    HVMH_0226 (metH)
Enzymes [BR:hmar01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     HVMH_0226 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding CdhD
Other DBs
NCBI-ProteinID: BBN58632
LinkDB
Position
complement(253819..257529)
AA seq 1236 aa
MTTRTDRLNLLKTLLNERVVVLDGAMGTMIQGLELTEEEFRGTRFADYHMDIKGNNDILV
MTQPEVIRDIHLQFLRNGVDIIETNSFNGTTIAQADYDMQDYVSELNLAAAKVAREACDI
AEQEDGKPRFVAGVLGPTNRTASISPDVNDPGFRNTSFDELVGAYKQATHALLEGGVDTI
LIETIFDTLNAKAAIFAVKEVEDEVGYEVPIMLSGTITDASGRTLSGQTTEAFYNAVAHA
EPLSVGLNCALGPEELRPYVEELSRVCESYVSIHPNAGLPNEFGEYDETPEQMAAEINVW
AEKGWINIIGGCCGTTPDHVAAMAEVAQKHPRRQLPEVKAACRLSGLEPLNIDESSLFVN
VGERNNVTGSAKFKRLIIEDNYDEAIEIAVKQVEEGAQIIDVNMDEGMLDAKACMTRFLN
LLASEPEASRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISLKEGEEKFIEQARLVKKYGA
AAIVMAFDEVGQADTLERKIEICSRSYKVLTEKVGFLPQDIIFDPNIFAVATGIEEHNNY
GLDFINAVTWIKQNLPHAKVSGGVSNVSFSFRGNNPVREAIHSVFLYYAIKEGMDMGIVN
AGQMAIYDDLPEKLRLAVEDVILNKDPEAGERLLEVAEEFRGDGSAASKVADLSWRENPI
EKRLEYALVKGITDYIEDDTEEARLKLGAPINVIEGPLMDGMNVVGDLFGSGKMFLPQVV
KSARVMKRAVAYLDPFLEAEKSEGQVQGKIVMATVKGDVHDIGKNIVGVVLQCNNFEVID
LGVMVPAEKILDTATEQGANVIGLSGLITPSLEEMVNVAKLMKERGMNLPLLIGGATTSK
AHTAVKIEPQYEHPVVYVKDASRAVGVAQSLISPDLKVDFATKIRAEYEQVREERKARAK
QVKRIPINKARENPSLTTDAWQDYTPGKPSFLGTKVLEDYPLEKLVERFDWSPFFQSWEL
HGLYPRILEDKVVGEEAKKLFADAQAMLQKILDEKWLTAKAVYGFFPANRVGDDIEIYTD
ETRSEVAHKLHHLRQQAEKKRGGANGCLSDFVAPKESGVADYVGLFAVTAGIGIDEHVER
FEKAHDDYNAIMLKALADRFAEAFAEKLHEIVRKEDWGYASDENLDNEDLIKERYQGIRP
AAGYPACPDHTEKGTIWEILQPDAKIGLEITENFAMTPTAAVSGTYFAHPESSYFGVGSL
GRDQVEDYAQRKGWSIEKAETWLAPNLGYDPEDFAN
NT seq 3711 nt   +upstreamnt  +downstreamnt
atgacaacaagaacagacagacttaacctcctcaaaactctacttaacgaacgcgtcgtg
gtgcttgatggcgcaatgggaacaatgatccaaggcctggagttaaccgaagaggagttt
cgcggaacgcgctttgccgactaccacatggatatcaaaggcaacaacgacatccttgtg
atgacccaaccggaagttattcgcgatattcatctacagtttttgcgcaatggcgtcgac
atcatcgagaccaactccttcaacggcaccaccatcgcacaggccgattacgacatgcag
gattacgtctccgagctaaacctagctgccgccaaagtggcgcgagaagcctgcgacatc
gccgaacaggaagatggtaaaccgcgtttcgttgccggggtgcttgggccaacaaaccgt
actgcatcgatttcacctgacgtcaatgatccgggcttccgcaacacgtcttttgatgaa
cttgtcggagcctacaagcaggcaactcacgctttgcttgaaggcggcgtcgacaccatc
ctgattgaaaccatcttcgacacactgaatgccaaagccgcgattttcgccgtcaaagaa
gtggaagacgaagtcggttatgaagtaccgatcatgttgtccggcaccattaccgacgct
tctggtcgtacgctttccggtcaaaccaccgaagcgttttataatgcggtcgcgcatgcc
gaaccattatcggttggtctgaactgtgccttggggccagaagaacttcgcccatatgtc
gaagaattgagccgagtttgcgaaagctatgtgtctatccacccgaatgccggtctgccg
aacgagtttggcgaatatgatgaaaccccggaacaaatggcggctgaaatcaatgtttgg
gcagaaaaaggctggatcaacattatcggtggctgttgcggtactacgccggatcacgtt
gctgccatggcggaagtcgcgcagaaacatcctcgccgtcaactgcctgaagtgaaagca
gcgtgtcgcttgtctggcctcgagccgctaaatattgacgaaagttcactgttcgtcaac
gtcggagagcgtaacaacgtcaccggttctgcaaaattcaaacgcctgattatcgaagac
aactacgacgaagcgattgaaatcgccgttaaacaggtagaagaaggcgcacagattatc
gacgtcaacatggacgaaggcatgttggacgccaaagcttgtatgacccgcttcttaaac
ctgctggcctccgagccggaagcgtcccgcgtaccgattatgatcgactcttccaaatgg
gaagtcattgaagccggcttgaagtgcattcaaggcaaaggcatcgtcaactctatttcc
ttgaaagaaggcgaagaaaagttcattgaacaagccagactggtgaaaaaatatggtgca
gcagccatcgtcatggcattcgacgaagttggtcaggcagacacgctggagcgcaaaata
gaaatctgttctcgctcatacaaagtgctgactgagaaagtcggtttcctgccgcaagac
attattttcgacccgaacattttcgccgtcgccaccgggattgaagaacacaataactac
ggtttagatttcatcaatgccgtgacttggattaaacaaaacctaccacacgcaaaagtg
tccggtggggtgtccaacgtgtccttttccttccgtggtaacaacccggttcgtgaagcg
attcactcggtattcctttactacgccatcaaagaaggcatggacatggggattgtgaat
gctgggcaaatggcgatttatgacgacctaccggaaaaactgcgtttggcggtagaagac
gtcatcctcaacaaagacccggaagccggagaacgcctactggaagtggccgaagaattc
cgtggcgatggttcggcagcgagcaaagttgccgatttatcatggcgtgaaaaccctatc
gaaaaacgtttggaatatgccttggtgaaaggcatcaccgactatatcgaagatgatacc
gaagaagctcgcctcaaacttggtgcgccgattaatgtcattgaaggtccattgatggac
ggcatgaacgtggtcggcgacctgttcggatccgggaaaatgttcctgccacaagtggtt
aaatccgcgcgcgtcatgaaacgcgccgtagcctatcttgacccattcctggaagcagaa
aaatccgaaggccaggtgcaaggcaaaatcgtcatggcgaccgttaaaggtgacgtacat
gatattggtaagaacatcgtcggcgtggtactgcaatgtaataacttcgaggtcattgat
cttggcgtgatggtgcctgcggaaaagattcttgataccgccactgaacaaggcgcgaat
gtcattggtctatccggtttgattaccccttctttggaagagatggtcaatgtcgccaag
ctgatgaaagagcgcggcatgaacctacctctgttgattggtggcgccaccacttccaaa
gcgcatactgcggtaaaaattgaaccacaatatgaacatccggtggtttacgtcaaagac
gcctctcgtgccgtcggtgttgcacaaagcttgatttctccggatttaaaagtcgacttc
gcaacaaaaatccgcgccgaatacgagcaggtgcgtgaagaacgtaaagcacgtgccaag
caggtcaagcgcattccaatcaacaaggcacgtgaaaacccatcacttactacagatgca
tggcaagactacacgccgggcaaaccgagtttcctcggcaccaaagtcctggaagattat
ccattggaaaaactggtcgagcgtttcgactggtcgcctttcttccaatcttgggaatta
cacggcttgtaccctcgcattcttgaggacaaggtcgtcggtgaagaagcgaagaaactc
tttgccgatgcacaagccatgctacaaaaaattctggatgaaaaatggctgaccgcaaaa
gccgtctatggtttcttccctgccaaccgcgtaggtgacgacattgaaatctataccgat
gaaacccgcagtgaagtggcgcataaactgcaccaccttcgccaacaggcagagaaaaag
cgtggtggtgccaacggctgtctatctgatttcgttgcgccaaaagaaagtggcgttgct
gactatgtcggtttgtttgcggtgacagcaggcatcggtatcgacgagcatgtcgagcgt
tttgaaaaagcccacgatgactataacgccatcatgctgaaagcgcttgccgaccgtttt
gccgaagcctttgcagagaagctacacgaaatcgtccgtaaagaagactgggggtatgcc
tcagatgagaacctggataacgaagatttgatcaaagagcgttaccaaggtattcgtcca
gctgctggctatcctgcttgcccagaccatactgaaaaaggcaccatttgggaaatcctg
caacctgatgccaaaatcggcttagagattaccgaaaattttgccatgacgccaactgcg
gcggtttcgggaacttactttgcacaccctgaatcgagctattttggtgttggttcgttg
ggtcgcgatcaagtcgaagactatgcacagcgtaaaggctggagcattgaaaaagctgaa
acctggctggcgccgaacttgggttacgacccggaagacttcgccaattaa

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