Hyphomicrobium sp. MC1: HYPMC_0536
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Entry
HYPMC_0536 CDS
T01557
Symbol
aceE
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
hmc
Hyphomicrobium sp. MC1
Pathway
hmc00010
Glycolysis / Gluconeogenesis
hmc00020
Citrate cycle (TCA cycle)
hmc00620
Pyruvate metabolism
hmc00785
Lipoic acid metabolism
hmc01100
Metabolic pathways
hmc01110
Biosynthesis of secondary metabolites
hmc01120
Microbial metabolism in diverse environments
hmc01200
Carbon metabolism
hmc01210
2-Oxocarboxylic acid metabolism
Module
hmc_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hmc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
HYPMC_0536 (aceE)
00020 Citrate cycle (TCA cycle)
HYPMC_0536 (aceE)
00620 Pyruvate metabolism
HYPMC_0536 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HYPMC_0536 (aceE)
Enzymes [BR:
hmc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
HYPMC_0536 (aceE)
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Paralog
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
CCB63770
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Position
524418..527093
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AA seq
891 aa
AA seq
DB search
MGKEEQKSSKAEDAEIQDWRESISSVIAYEGTERADDILGEVVERARASGAAIPFASSTA
YINTIPVRDEAPLPGDRDLEHRIAAAIRWNAAAMVLRSNKESSELGGHIASYQSAATLYE
TGFNHFWHAPSEEHGGDLVLIQGHSSPGIYARAFLEGRLTEDQLLNFRQEVGGHGLSSYP
HPWLMPDFWQFPTVSMGLGPLMAIYQARFLKYLHARGLADTEGRKVWVFCGDGEMDEPES
LGAISLAGREKLDNLIFVINCNLQRLDGPVRGNGKIIQELERNFRGAGWNVIKVIWGSQW
DELLAKDTTGKLRQLMEECVDGEYQVFKSRDGAFIRKHFFGRYPETAALVEDWSDDKIWR
LTRGGHDPSKVYAAYAEAVAHKNQPTCILAKTVKGYGMGAAGEGTMLAHSSKKMDIDTLR
QFRDRFKIPVSDAEMEKLPFVRLPKGSPEDDYLHAMRDKLGGYLPQRRRKSISLEAPPLS
LFESQLKGSDGREISTTMAFVRILTALMRDKALGRRIVPIVPDESRTFGMEGMFRQFGIF
SQVGQLYVPQDADQLMFYKEDKHGQMLQEGINEAGAMASWIAAATSYATSNVPMVPFYIF
YSMFGFQRVGDLAWAAGDERSRGFLIGGTSGRTTLNGEGLQHEDGHSHLMSATVPNCVSY
DPTFNYEVAVIIQSGLKRMLQDQEDVFFYLTLLNENYEHPPMPEGAEAGIIKGMYLFREA
AKNAKGHKVQLMGSGAILREVIAAADLLRDDWGVEADIWSVTSFTELAREAHDVERWNLL
HPTETPRVPYVTQMVSGRGEGPVIASTDYIKMFAEQIRPSVPNKYSVLGTDGFGRSDYRR
TLRYFFEVDRHFVTIAALKALADENKIPSIKVAEAISKYGIDPEKPNPAHS
NT seq
2676 nt
NT seq
+upstream
nt +downstream
nt
atgggcaaagaggaacaaaagtcttcgaaggccgaggacgccgaaatccaggattggcgc
gagtcgatctcgtccgtcatcgcctacgaaggcaccgagcgggccgacgatattctgggt
gaggtggttgagcgggcgcgtgcaagcggtgcagcgatcccgtttgcatcgagcacggcg
tacatcaacactatccccgttcgcgatgaggcaccgcttccgggcgatcgcgatcttgag
catcggattgccgcggcaatccgatggaacgccgccgcgatggtgcttcgctccaacaag
gagtcgagcgagcttggcgggcacatcgccagttatcagtcggcggcgacgctttatgaa
accggcttcaatcatttctggcacgcgccgtcagaggaacatggcggcgatctcgtgttg
atccaaggccactcttcccccggcatttatgcgcgagcgtttctggaagggcgtcttacc
gaagatcagcttttgaatttccggcaggaagtcggcgggcacgggctgtcatcttacccg
catccatggctgatgccggatttctggcaattcccgacggtctccatgggcctcgggccg
cttatggcaatctatcaggcacgctttctcaaatatctgcacgcacgcgggcttgcggac
accgagggccggaaggtttgggtattttgcggcgacggcgagatggacgagccggaaagt
ctcggcgcgatttcgctggcgggccgagagaagctcgacaacctaattttcgtcatcaat
tgcaacctgcagcgcctggacgggccggtgcgcggcaacggcaagatcatccaggaactc
gaacggaatttccgcggtgccggatggaacgtcatcaaggttatttggggttcgcagtgg
gacgagcttctggcgaaggacacgacgggcaagcttcgccaattgatggaagagtgcgtc
gatggcgaataccaagtcttcaagtcgcgcgacggggctttcattcgtaagcacttcttc
ggacgctatccggagacggcggcgctcgtcgaagattggtcggacgacaagatctggcgg
ctgacgcgcggcggtcacgatccctcgaaagtctatgcggcttatgccgaagcggttgcg
cacaagaaccagccgacgtgcatcctggcgaaaaccgtcaaaggctacggcatgggcgcg
gcgggcgagggcacgatgctcgcgcactcgtccaagaagatggacatcgatacgctgcgt
cagttccgcgatcgcttcaagataccggtgagcgacgcggagatggaaaagctaccgttc
gtccgcctgccgaaagggtcgccggaagacgactatctgcacgcgatgcgcgacaagctc
ggtggttatcttccgcaacggcggcggaagtcgatctcgctcgaagcaccgccgttgtcg
ctgttcgaatcgcaactcaaaggctcggacggacgcgagatttcgacgacaatggcgttc
gtccgcattctgacggcgctgatgcgcgacaaggcgctgggtcgccgcatcgtgccgatc
gtgccggatgaaagccgcacgttcggcatggaaggtatgttccggcagttcggcattttc
agtcaggtcgggcagctctacgtgccgcaagatgccgatcaactgatgttctataaggaa
gacaagcacggtcagatgctgcaggaaggcatcaacgaggctggtgcgatggcgtcgtgg
atcgcggccgcaacgagctacgcgacgtcgaacgtgccgatggtgccgttctatatcttc
tattcgatgttcggattccagcgcgtcggcgatcttgcctgggcggccggtgacgagcgt
tcgcgcggctttctgatcggcggcacgtcggggcggacgacactcaacggcgaaggtttg
cagcatgaagatgggcatagccatctcatgtcggcgacggtgccgaactgcgtgtcctac
gatccgacattcaactacgaggtcgccgtcatcattcaaagcggtctcaagcgcatgctg
caggatcaggaggacgtgttcttctatctgacgctgctgaacgagaactacgagcatccg
ccgatgccggagggtgctgaggccggcatcatcaaggggatgtatctttttcgcgaggcg
gcgaagaatgccaaaggccacaaggtgcagttgatgggctcgggcgctattctgcgcgag
gtcatcgcggccgccgatttgttgcgcgacgattggggtgtggaagccgatatctggagc
gtgacgagcttcaccgagcttgcgcgcgaagcgcacgacgttgagcgctggaacctgctg
cacccgacagagacgccgcgcgtgccctatgtcacgcagatggtttcgggccgcggcgaa
gggccggtgattgcatcgaccgactacatcaagatgtttgcggagcaaatccgtccgtcc
gtgccgaacaaatattcggtgcttggaacggacggctttggccgctcggactatcgccgc
acgctgcggtatttcttcgaggtcgatcgtcatttcgtgacgattgcggcgctgaaggcg
ctggctgatgaaaataagattccgtcgatcaaggtggcggaagccatctcgaaatacggg
attgatcccgaaaagcccaatcccgcgcatagctga
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